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Topic Review Peer Reviewed
Exsolution Catalysts—Increasing Metal Efficiency
Exsolution catalysts are perovskite oxide-based materials that can exsolve catalytically active dopant elements as nanoparticles covering the surface, while the perovskite backbone can act as a stable support material. Thus, under proper conditions, a highly catalytically active and stable catalyst surface can be achieved. For many catalytic materials, precious metals or non-abundant elements play a key role in high catalytic activity. As these elements are often expensive or their supply is ecologically and ethically problematic, the replacement, or at the least reduction in the necessary amount used, is a common aim of current research. One strategy to do so is utilizing exsolution catalysts, as the active elements can be very selectively exsolved, and hence only very small doping amounts are sufficient for excellent results. This approach enables catalyst design with very high active metal efficiency.
  • 1.6K
  • 13 Apr 2022
Topic Review
Edible Flowers
Edible flowers have been widely consumed for ages until now. The attractive colors and shapes, exotic aroma, and delightful taste make edible flowers very easy to attain. Moreover, they also provide health benefits for consumers due to the unique composition and concentration of antioxidant compounds in the matrices. Knowing the bioactive compounds and their functional properties from edible flowers is necessary to diversify the usage and reach broader consumers.
  • 1.6K
  • 01 Jun 2021
Topic Review
Mixed-Matrix Membranes for Gas Separation
Nanocomposite membranes, obtained by dispersing solid particles within a polymeric matrix, are referred to as mixed-matrix membranes (MMMs) and are potentially capable to exceed the trade-off restrictions between membrane permeability and selectivity, that is an intrinsic trait for polymeric membranes applied to gas separation. Making the most appropriate combination of filler and polymer is an exciting challenge for materials scientists.
  • 1.6K
  • 28 Jan 2022
Topic Review
Inclusive EFL Teaching for Young Students
The Ministry of Education emphasizes that school principals should attempt to train teachers in special education and in assisting students with special education needs (SEN) in regular classes via supportive services. However, EFL teachers usually have insufficient training and do not know how to adjust their teaching methods for students with SEN in regular classes. 
  • 1.6K
  • 31 May 2022
Topic Review
Vision-Based Autonomous Vehicle Systems
Autonomous vehicle systems (AVS) have advanced at an exponential rate, particularly due to improvements in artificial intelligence, which have had a significant impact on social as well as road safety and the future of transportation systems. Deep learning is fast becoming a successful alternative approach for perception-based AVS as it reduces both cost and dependency on sensor fusion.
  • 1.6K
  • 12 Jul 2022
Topic Review
Earth Rainfall Climatology
Earth rainfall climatology Is the study of rainfall, a sub-field of meteorology. Formally, a wider study includes water falling as ice crystals, i.e. hail, sleet, snow (parts of the hydrological cycle known as precipitation). The aim of rainfall climatology is to measure, understand and predict rain distribution across different regions of planet Earth, a factor of air pressure, humidity, topography, cloud type and raindrop size, via direct measurement and remote sensing data acquisition. Current technologies accurately predict rainfall 3–4 days in advance using numerical weather prediction. Geostationary orbiting satellites gather IR and visual wavelength data to measure realtime localised rainfall by estimating cloud albedo, water content, and the corresponding probability of rain. Geographic distribution of rain is largely governed by climate type, topography and habitat humidity. In mountainous areas, heavy precipitation is possible where upslope flow is maximized within windward sides of the terrain at elevation. On the leeward side of mountains, desert climates can exist due to the dry air caused by compressional heating. The movement of the monsoon trough, or intertropical convergence zone, brings rainy seasons to savannah climes. The urban heat island effect leads to increased rainfall, both in amounts and intensity, downwind of cities. Warming may also cause changes in the precipitation pattern globally, including wetter conditions at high latitudes and in some wet tropical areas. Precipitation is a major component of the water cycle, and is responsible for depositing most of the fresh water on the planet. Approximately 505,000 cubic kilometres (121,000 cu mi) of water falls as precipitation each year; 398,000 cubic kilometres (95,000 cu mi) of it over the oceans. Given the Earth's surface area, that means the globally averaged annual precipitation is 990 millimetres (39 in). Climate classification systems such as the Köppen climate classification system use average annual rainfall to help differentiate between differing climate regimes. Most of Australia is semi-arid or desert, making it the world's driest continent. Australia's rainfall is mainly regulated by the movement of the alien monsoon trough during the summer rainy season, with lesser amounts falling during the winter and spring in its southernmost sections. Almost whole North Africa is semi-arid, arid or hyper-arid, containing the Sahara Desert which is the largest hot desert in the world, while central Africa (known as Sub-Saharan Africa) sees an annual rainy season regulated by the movement of the intertropical convergence zone or monsoon trough, though the Sahel Belt located at the south of the Sahara Desert knows an extremely intense and a nearly permanent dry season and only receives minimum summer rainfall. Across Asia, a large annual rainfall minimum, composed primarily of deserts, stretches from the Gobi Desert in Mongolia west-southwest through Pakistan and Iran into the Arabian Desert in Saudi Arabia. In Asia, rainfall is favored across its southern portion from India east and northeast across the Philippines and southern China into Japan due to the monsoon advecting moisture primarily from the Indian Ocean into the region. Similar, but weaker, monsoon circulations are present over North America and Australia . In Europe, the wettest regions are in the Alps and downwind of bodies of water, particularly the Atlantic west coasts. Within North America, the drier areas of the United States are the Desert Southwest, Great Basin, valleys of northeast Arizona, eastern Utah, central Wyoming, and the Columbia Basin. Other dry regions within the continent are far northern Canada and the Sonoran Desert of northwest Mexico. The Pacific Northwest United States, the Rockies of British Columbia, and the coastal ranges of Alaska are the wettest locations in North America. The equatorial region near the Intertropical Convergence Zone (ITCZ), or monsoon trough, is the wettest portion of the world's continents. Annually, the rain belt within the tropics marches northward by August, then moves back southward into the Southern Hemisphere by February and March.
  • 1.6K
  • 18 Oct 2022
Topic Review
History of Automated Electrocardiogram Interpretation
The most recent development in the field of automated electrocardiogram (ECG) analysis has been the use of artificial intelligence (AI), including a variety of machine learning techniques to aid interpretation. One of the authors (PWM) was involved in the use of neural networks in the early 1990s but at that time, use of a simple neural network did not prove to be of any great advantage in ECG interpretation compared to the use of more basic, straightforward diagnostic criteria.  This entry describes the development of automated ECG interpretation since its beginnings in Washington DC around 1960 up until the present.
  • 1.6K
  • 15 Feb 2023
Topic Review
SARS-CoV-2 and HIV Surface Envelope Glycoproteins
Although very different, in terms of their genomic organization, their enzymatic proteins, and their structural proteins, HIV and SARS-CoV-2 have an extraordinary evolutionary potential in common. Faced with various selection pressures that may be generated by treatments or immune responses, these RNA viruses demonstrate very high adaptive capacities, which result in the continuous emergence of variants and quasi-species. HIV and SARS-CoV-2 first recognize a lipid raft microdomain that acts as a landing strip for viral particles on the host cell surface. In the case of mucosal cells, which are the primary targets of both viruses, these microdomains are enriched in anionic glycolipids (gangliosides) forming a global electronegative field. Both viruses use lipid rafts to surf on the cell surface in search of a protein receptor able to trigger the fusion process. This implies that viral envelope proteins are both geometrically and electrically compatible to the biomolecules they select to invade host cells.
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  • 23 Apr 2023
Topic Review
Jackfruit Waste Utilizd in Sustainable Energy and Biochemicals
Jackfruit (Artocarpus heterophyllus L.) trees are known to produce huge fruits from their stems and are unique in terms of food utilization as vegetables and fruits. Jackfruit trees are cultivated throughout the lowlands in south and southeast Asian countries. In addition, it is found in east Africa, as well as throughout Brazil and Caribbean nations such as Jamaica.
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  • 18 Sep 2023
Topic Review
Applications of Biodegradable Poly Blends/Composites
Biodegradable poly(ɛ-caprolactone) (PCL) and its composites or blends have received a lot of attention in the past because of their potential applications in human life and environmental remediation. Greater efforts have been made to develop biodegradable chemical materials as adsorbents that do not pollute the environment in order to replace traditional materials. 
  • 1.6K
  • 09 Nov 2023
Topic Review
Intrusion Detection and Datasets
With the significant increase in cyber-attacks and attempts to gain unauthorised access to systems and information, Network Intrusion-Detection Systems (NIDSs) have become essential detection tools. Anomaly-based systems use machine learning techniques to distinguish between normal and anomalous traffic. They do this by using training datasets that have been previously gathered and labelled, allowing them to learn to detect anomalies in future data. However, such datasets can be accidentally or deliberately contaminated, compromising the performance of NIDS.
  • 1.6K
  • 30 Jan 2024
Topic Review
Hydroxyapatite Nanoparticles in Drug Delivery
A biomaterial is a synthetic material used to replace part of a living system or a material meant to be in contact with living tissue. In this sense, biomaterials can be categorized into polymers, liposomes, micelles, dendrimers, and calcium phosphate (CaP) nanoparticles, where each will show a different type of bioactivity. Hydroxyapatite (HAP) has been the gold standard in the biomedical field due to its composition and similarity to human bone. HAP nanoparticles have been used as vehicles for delivery due to their affinity to DNA, proteins, several drugs, and proper release activity.
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  • 02 Nov 2021
Topic Review
Membrane Technologies in Dairy Industry
Membrane technologies can be used in the dairy industry for many applications, such as milk clarification or fractioning and a concentration increase in specific components or the separation of them, since they cover a huge range of pore sizes (from 0 to 2 μm) and MWCOs (from 1 to 100,000 Da). For instance, MF can be used for fat globule (10 μm) fractionation as well as bacteria and spore (1 μm) removal. UF can be used for casein micelles (100 nm) or serum protein (10 nm) separation, whereas NF and RO can be used for lactose (1 nm), salt (0.1 nm) and water recovery.
  • 1.6K
  • 18 Nov 2021
Topic Review
Non-alcoholic Fatty Liver Disease Pathogenesis and Oxidative Stress
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple factors, which may partly explain why it still remains an orphan of adequate therapies. It highlights the interaction between oxidative stress (OS) and disturbed lipid metabolism. Several reactive oxygen species generators, including those produced in the gastrointestinal tract, contribute to the lipotoxic hepatic (and extrahepatic) damage by fatty acids and a great variety of their biologically active metabolites in a “multiple parallel-hit model”. This leads to inflammation and fibrogenesis and contributes to NAFLD progression. The alterations of the oxidant/antioxidant balance affect also metabolism-related organelles, leading to lipid peroxidation, mitochondrial dysfunction, and endoplasmic reticulum stress. This OS-induced damage is at least partially counteracted by the physiological antioxidant response. Therefore, modulation of this defense system emerges as an interesting target to prevent NAFLD development and progression. For instance, probiotics, prebiotics, diet, and fecal microbiota transplantation represent new therapeutic approaches targeting the gut microbiota dysbiosis. The OS and its counter-regulation are under the influence of individual genetic and epigenetic factors as well.
  • 1.6K
  • 14 Feb 2022
Topic Review
Protein Phase Separation
Phase separation is a process by which a well-mixed solution of macromolecules such as proteins or nucleic acids spontaneously separates into two phases: a dense phase and a dilute phase.
  • 1.6K
  • 06 Dec 2022
Topic Review
Short Bowel Syndrome (SBS)
Short bowel syndrome (SBS) is a malabsorptive condition that is most often caused by a massive resection of the small intestine. Its prevalence is 3–4 per million and occurs in about 15% of adult patients undergoing an intestinal resection, either massive (3/4) or from multiple sequential resections (1/4). SBS and intestinal failure (IF) are not necessarily synonymous. Intestinal failure describes the state when an individual’s gastrointestinal function is inadequate to maintain his or her nutrient and hydration status without intravenous or enteral supplementation. 
  • 1.6K
  • 22 Jan 2024
Topic Review
Evapotranspiration
Accurate evapotranspiration (ET) estimation is important in understanding the hydrological cycle and improving water resource management. The operational simplified surface energy balance (SSEBop) model can be set up quickly for the routine monitoring of ET. Several studies have suggested that the SSEBop model that simulated ET has performed inconsistently across the United States. There are few detailed studies on the evaluation of ET simulated by SSEBop in other regions. To explore the potential and application scope of the SSEBop model, more evaluation of the ET simulated by SSEBop is clearly needed. We calculated the SSEBop model-based ET (ETSSEBopYRB) with the input of MOD11A2 and climate variables in the Yellow River Basin (YRB), China. We also compared the ETSSEBopYRB with eight coarse resolution ET products, including China ETMTE produced by the upscaling energy flux method, China ETCR generated by the nonlinear complementary relationship model, three global products based on the logic of Penman-Monteith (ETPMLv2, ETMODIS and ETBESS), two global ET products based on the surface energy balance (ETSEBS, ETSSEBopGlo), and integrated ET products based on the Bayesian model averaging method (ETGLASS), by the annual ET derived from the water balance method (WB-ET) in fourteen catchments. We found that ETSSEBopYRB and the other eight ET products were able to explain 23 to 52% variability in water balance ET of fourteen small catchments in YRB. ETSSEBopYRB has better agreement with WB-ET than ETSEBS, ETMODIS, ETCR and ETGLASS, with a lower RMSE (88.3 mm yr-1 vs 121.7 mm yr-1), higher R2 (0.49 VS 0.43) and lower absolute RPE (–3.3% VS –19.9%) during the years 2003–2015. We also found that the uncertainties of the spatial pattern of the average annual ET and the ET trend are still large in different ET products. Third, we found that the free global ET product derived from the SSEBop model (ETSSEBopGlo) highly underestimated the annual total ET trend of the YRB. Poor performance of the land surface temperature product of MOD11A2 in 2015 caused the large ETSSEBopYRB uncertainty at eight-day scale and monthly scale. Further evaluation of the ET based on the SSEBop model in site measurements is needed.
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  • 14 Jan 2022
Topic Review
Respiratory System and its Microbiome
Several studies suggest the importance of preserving the micro-ecosystem of commensal, symbiotic and pathogenic microbes of the respiratory system, and, more recently, its relationship with the intestinal microbiome. However, recent studies investigate how it leads to the maintenance of human health, also in relation to some factors such as the effect of age, diet and others, making its composition and stability better understood.  
  • 1.6K
  • 09 Nov 2020
Topic Review
RBUD
RBUD, read-based metagenomics profiling for unestablished database, is a new functional potential analysis approach for whole microbial genome shotgun sequencing. Based on whole metagenome shotgun sequencing data, it can be used to analysis microbial species and functions, especially for the study without relevant reference database. RBUD method is optimized by omitting the steps of contigs assembly and ORF prediction which improves the utilization of sequencing data and shortens the time of data analysis. In addition, RBUD method includes the steps of establishing databases of microorganisms from different sources to expand its application, which is a great help for small-sample research and can avoid the lack of reference database. By compared RBUD with the existing methods in practical applications, RBUD has great advantages in both species and functional analysis.
  • 1.6K
  • 21 Oct 2020
Topic Review
Photodynamic Therapy
Photodynamic therapy (PDT) is a promising therapeutic strategy for cancers where surgery and radiotherapy cannot be effective. PDT relies on the photoactivation of photosensitizers, most of the time by lasers to produced reactive oxygen species and notably singlet oxygen. The major drawback of this strategy is the weak light penetration in the tissues. To overcome this issue, recent studies proposed to generate visible light in situ with radioactive isotopes emitting charged particles able to produce Cerenkov radiation. In vitro and preclinical results are appealing, but the existence of a true, lethal phototherapeutic effect is still controversial.
  • 1.6K
  • 15 Dec 2020
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