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Topic Review
The Effect of Menopause on Antipsychotic Response
Whenever estrogen levels decline, psychosis symptoms in women increase. At menopause, this can happen in two main ways: (a) the loss of estrogen (mainly estradiol) can directly affect central neurotransmission, leading to increase in schizophrenia-related symptoms, and (b) the loss of estrogen can decrease the synthesis of enzymes that metabolize antipsychotic drugs, thus weakening their efficacy.
  • 1.6K
  • 04 Nov 2022
Topic Review
Biofilm Lifestyle in Urinary Tract Infections
Urinary tract infections (UTIs) represent one of the most common infections that are frequently encountered in health care facilities. One of the main mechanisms used by bacteria that allows them to survive hostile environments is biofilm formation. Biofilms are closed bacterial communities that offer protection and safe hiding, allowing bacteria to evade host defenses and hide from the reach of antibiotics. Inside biofilm communities, bacteria show an increased rate of horizontal gene transfer and exchange of resistance and virulence genes.
  • 1.6K
  • 16 Jan 2023
Topic Review
Atypical Positional Vertigo
Benign paroxysmal positional vertigo is the most frequent cause of vertigo. As its name indicates, it is characterized by vertigo episodes of sudden onset and end, triggered by changes in head’s position with regard to gravity. It is located in the labyrinth, and its cause is mechanical. However, this is an etiologic diagnosis, reached after questioning and examining the patient. Based on what patients report, the duration of symptoms lasts seconds; however, many overestimate the duration of the vertiginous sensation. The trigger effect of positional changes is a key issue to be addressed. A great variability of autonomic symptoms, including nausea and vomiting, can accompany BPPV. Gait instability, headache, and additional neurologic complaints are potential red flags in the differential diagnosis. With a defined position trigger effect, it is the neurologist’s job to perform an examination to confirm the diagnosis of paroxysmal positional vertigo (PPV), and by virtue of the vertigo duration and nystagmus characteristics, to determine lesion localization (peripheral versus central) and to design a management plan.
  • 1.6K
  • 26 May 2022
Topic Review
Technological Breakthroughs in Sport
We are currently witnessing an unprecedented era of digital transformation in sports, driven by the revolutions in Artificial Intelligence (AI), Virtual Reality (VR), Augmented Reality (AR), and Data Visualization (DV). These technologies hold the promise of redefining sports performance analysis, automating data collection, creating immersive training environments, and enhancing decision-making processes. Traditionally, performance analysis in sports relied on manual data collection, subjective observations, and standard statistical models. These methods, while effective, had limitations in terms of time and subjectivity.
  • 1.6K
  • 26 Sep 2025
Topic Review
Atrial Fibrillation Diagnosis Measurements
Atrial Fibrillation (AF) is a heart rhythm disorder. Hence, AF diagnosis is based on measurements which reflect the activity of the heart. Detectable symptoms of the disease might not be present all the time. Therefore, the measurement duration is positively correlated with the AF detection rate. Suitable measurements include photoplethysmogram, electrocardiogram, and heart rate. The data volume, produced through long term measurement, mandates computer support to automate the AF detection task.
  • 1.6K
  • 30 Oct 2020
Topic Review
AI&ML for Medical Sector
This work represents a comprehensive analysis of the potential AI, ML, and IoT technologies for defending against the COVID-19 pandemic. The existing and potential applications of AI, ML, and IoT, along with a detailed analysis of the enabling tools and techniques are outlined. A critical discussion on the risks and limitations of the aforementioned technologies are also included.
  • 1.6K
  • 21 Jan 2021
Topic Review
MFN2 Gene
mitofusin 2
  • 1.6K
  • 22 Dec 2020
Topic Review
Fabrication and Biomedical Applications of Functional Nanoporous Materials
Functional nanoporous materials are categorized as an important class of nanostructured materials because of their tunable porosity and pore geometry (size, shape, and distribution) and their unique chemical and physical properties as compared with other nanostructures and bulk counterparts. Progress in developing a broad spectrum of nanoporous materials has accelerated their use for extensive applications in catalysis, sensing, separation, and environmental, energy, and biomedical areas. 
  • 1.6K
  • 16 Mar 2022
Topic Review
Chemical Alternatives for Fixing Carbon Dioxide
Carbon is the most important element of organic matter, forming the major part of its dry weight. Elemental carbon exists in the atmosphere as carbon dioxide (CO2) and is dissolved in water, rocks, and soils as carbonic acid (H2CO3), bicarbonates, and carbonates. In fossil fuels, it exists as carbon rings or chains and in biomolecules such as nucleic acids, carbohydrates, proteins, and lipids. Atmospheric CO2 is the major cause for global warming through the greenhouse effect; hence, carbon dioxide emissions must be strictly regulated to minimize the greenhouse effect.
  • 1.6K
  • 13 Apr 2022
Topic Review
Paracetamol
Paracetamol (acetaminophen) is one of the most commonly prescribed drugs worldwide. Synthetized over 150 years ago, paracetamol is highly efficient as analgesic and antipyretic and is on the list of the World Health Organization’s essential medicines. Paracetamol is also a hypothermic agent.
  • 1.6K
  • 28 Apr 2022
Topic Review
State of Fear
State of Fear is a 2004 techno-thriller novel by Michael Crichton, in which eco-terrorists plot mass murder to publicize the danger of global warming. Despite being a work of fiction, the book contains many graphs and footnotes, two appendices, and a 20-page bibliography in support of Crichton's beliefs about global warming. Many climate scientists, science journalists, environmental groups, and science advocacy organisations dispute Crichton's views on the science as being error-filled and distorted. The novel had an initial print run of 1.5 million copies and reached the #1 bestseller position at Amazon and #2 on The New York Times Best Seller list for one week in January 2005. The novel itself has garnered mixed reviews, with some literary reviewers stating that the book's presentation of facts and stance on the global warming debate detracted from the book's plot.
  • 1.6K
  • 19 Oct 2022
Topic Review
Intestinal Enteroendocrine Cells in Parkinson’s Disease
Intestinal epithelial enteroendocrine cells (EECs) residing in the epithelium throughout intestine are the key regulators orchestrating the communication along the brain-gut-microbiota axis. On one hand, EECs sense changes in luminal microorganisms via microbial metabolites; on the other hand, they communicate with host body systems via neuroendocrine molecules. Therefore, EECs are believed to play important roles in neurological and psychiatric disorders.
  • 1.6K
  • 28 Oct 2022
Topic Review
Lane Marking Detection Using Deep Neural Networks
Lane marking recognition is one of the most crucial features for automotive vehicles as it is one of the most fundamental requirements of all the autonomy features of Advanced Driver Assistance Systems (ADAS).
  • 1.6K
  • 27 Oct 2022
Topic Review
The Approaches Used in China Civic-Moral Education
Civic-moral education is a topic that has been widely discussed globally. In China, civic-moral education has a long history and presents different characteristics and methods from other countries due to political, economic, and cultural factors. 
  • 1.6K
  • 19 Oct 2023
Topic Review
Interventional Management of Nutcracker and Wilkie Syndromes
Nutcracker and Wilkie syndromes are rare mesoaortic compression entities, and their association is even less common. Data on interventional treatment of these pathologies are still scarce, but results from limited case series are encouraging. 
  • 1.6K
  • 20 Sep 2022
Topic Review
Superficial Spindle Cell Mesenchymal Tumors
Superficial spindle cell mesenchymal tumors form a diverse group of lesions with benign and malignant entities that are often very similar clinically and/or histologically. In children, the patient’s age; the lesion site; the presentation as a mass, nodule, or plaque; and the location in the dermis or subcutis are important features that will guide the dermatologist and the pathologist.
  • 1.6K
  • 02 Oct 2021
Topic Review
Inheriting Genetic Conditions
It is not always easy to determine whether a condition in a family is inherited. A genetics professional can use a person's family history (a record of health information about a person's immediate and extended family) to help determine whether a disorder has a genetic component.
  • 1.6K
  • 24 Dec 2020
Topic Review
Combining Experimental and Computational Methods
The integration of experimental and computational methods can assist and enrich the interpretation of the experimental results, providing new detailed molecular understanding of the systems.
  • 1.6K
  • 14 Jan 2021
Topic Review
MiRNA-7
MicroRNAs (miRNAs, miRs) are small non-coding RNA (ncRNA) molecules capable of regulating post-transcriptional gene expression. Imbalances in the miRNA network have been associated with the development of many pathological conditions and diseases, including cancer. Recently, miRNAs have also been linked to the phenomenon of multidrug resistance (MDR). MiR-7 is one of the extensively studied miRNAs and its role in cancer progression and MDR modulation has been highlighted. MiR-7 is engaged in multiple cellular pathways and acts as a tumor suppressor in the majority of human neoplasia. Its depletion limits the effectiveness of anti-cancer therapies, while its restoration sensitizes cells to the administered drugs.
  • 1.6K
  • 25 Feb 2021
Topic Review
Clinical Trials of Parkinson’s Disease
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that currently has no cure, but treatments are available to improve PD symptoms and maintain quality of life.
  • 1.6K
  • 03 Aug 2021
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