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Topic Review
The Chemistry of Reactive Oxygen Species Revisited
Living species are continuously subjected to all extrinsic forms of reactive oxidants and others that are produced endogenously. There is extensive literature on the generation and effects of reactive oxygen species (ROS) in biological processes, both in terms of alteration and their role in cellular signaling and regulatory pathways. Cells produce ROS as a controlled physiological process, but increasing ROS becomes pathological and leads to oxidative stress and disease. The induction of oxidative stress is an imbalance between the production of radical species and the antioxidant defense systems, which can cause damage to cellular biomolecules, including lipids, proteins and DNA. Cellular and biochemical experiments have been complemented in various ways to explain the biological chemistry of ROS oxidants. However, it is often unclear how this translates into chemical reactions involving redox changes. 
  • 1.7K
  • 30 Sep 2022
Topic Review
A Promising Downsampling Alternative in a Neural Network
Downsampling, which aims to improve computational efficiency by reducing the spatial resolution of feature maps, is a critical operation in neural networks. Upsampling also plays an important role in neural networks. It is often used for image super-resolution, segmentation, and generation tasks via the reconstruction of high-resolution feature maps during the decoding stage in the neural network.
  • 1.7K
  • 04 Dec 2023
Topic Review
Three-Dimensional Printing
Additive manufacturing with an emphasis on 3D printing has recently become popular due to its exceptional advantages over conventional manufacturing processes. However, 3D printing process parameters are challenging to optimize, as they influence the properties and usage time of printed parts. Therefore, it is a complex task to develop a correlation between process parameters and printed parts’ properties via traditional optimization methods. A machine-learning technique was recently validated to carry out intricate pattern identification and develop a deterministic relationship, eliminating the need to develop and solve physical models. In machine learning, artificial neural network (ANN) is the most widely utilized model, owing to its capability to solve large datasets and strong computational supremacy.
  • 1.7K
  • 17 Feb 2021
Topic Review
Plant Biotechnology based COVID19-vaccines
Many pathogenic viral pandemics have caused threats to global health; the COVID-19 pandemic is the latest. Its transmission is growing exponentially all around the globe, putting constraints on the health system worldwide. A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causes this pandemic. Many candidate vaccines are available at this time for COVID-19, and there is a massive international race underway to procure as many vaccines as possible for each country. However, due to heavy global demand, there are strains in global vaccine production. The use of a plant biotechnology-based expression system for vaccine production also represents one part of this international effort, which is to develop plant-based heterologous expression systems, virus-like particles (VLPs)-vaccines, antiviral drugs, and a rapid supply of antigen-antibodies for detecting kits and plant origin bioactive compounds that boost the immunity and provide tolerance to fight against the virus infection. This review will look at the plant biotechnology platform that can provide the best fight against this global pandemic.
  • 1.7K
  • 04 Aug 2021
Topic Review
Parthenin
Parthenin, a sesquiterpene lactone of pseudoguaianolide type, is the representative secondary metabolite of the tropical weed Parthenium hysterophorus (Asteraceae). It accounts for a multitude of biological activities, including toxicity, allergenicity, allelopathy, and pharmacological aspects of the plant. Thus far, parthenin and its derivatives have been tested for chemotherapeutic abilities, medicinal properties, and herbicidal/pesticidal activities. However, due to the lack of toxicity-bioactivity relationship studies, the versatile properties of parthenin are relatively less utilised. The possibility of exploiting parthenin in different scientific fields (e.g., chemistry, medicine, and agriculture) makes it a subject of analytical discussion. It is important to highlight that the toxic nature of parthenin can be overcome by thoroughly understanding its structural basis, designing suitable derivatives, and deciding the appropriate doses.
  • 1.7K
  • 09 Oct 2021
Topic Review
Ion Transport of Two-Dimensional Materials
Ion transport is one of the basic principles of the development of various different technologies that can improve the quality of our lives, such as the ever-growing importance of clean and sustainable energy, the reduction of water scarcity and even the improvement of fundamental medical application knowledge. Ion transport can be defined as the movement of charged ions from one position to another in ion electrolyte solutions within both organic (living cells) and inorganic (polymer materials) systems. Ion transport can be encouraged through various mechanisms such as electrochemical diffusion, ion active transport requiring external energy or bulk transport for the conversion of adenosine triphosphate (ATP) and energy consumption in biological functions.
  • 1.7K
  • 27 Oct 2021
Topic Review
Metabolism and Bioconversion of PET Monomers
Polyethylene terephthalate (PET) is a widely used plastic that is polymerized by terephthalic acid (TPA) and ethylene glycol (EG). Pseudomonas sp., and E. coli have ability to utilize EG. In A. woodii, EG can be utilized by an acetaldehyde/ethanol pathway while it is consumed by a glyoxylic acid pathway in Pseudomonas sp. and E. coli. 
  • 1.7K
  • 19 Apr 2022
Topic Review
Graphene-Based Nanocomposites
Graphene is an allotrope of carbon consisting of a single layer of atoms arranged in a two-dimensional honeycomb lattice. Carbon atoms are bonded with a covalent sp2bond with a single free electron, which accounts for the conductivity of graphene. Graphene is attracting great interests from the physical, chemical, and biomedical fields as a novel nanomaterial with exceptional physical properties, including extremely high thermal conductivity, excellent electrical conductivity, high surface-to-volume ratio, remarkable mechanical strength, and biocompatibility.
  • 1.7K
  • 27 Jan 2022
Topic Review
Renoprotective Effects of Mangiferin
Both acute and chronic kidney diseases substantially contribute to the morbidities and mortality of patients worldwide. The existing therapeutics, which are mostly developed from synthetic sources, present some unexpected effects in patients, provoking researchers to explore potential novel alternatives. Natural products that have protective effects against various renal pathologies could be potential drug candidates for kidney diseases. Mangiferin is a natural polyphenol predominantly isolated from Mangifera indica and possesses multiple health benefits against various human ailments, including kidney disease. 
  • 1.7K
  • 21 Feb 2022
Topic Review
Application of Encapsulated Limonene in Agri-Food Industry
Limonene or 4-isopropenyl-1-methylcyclohexene (C10H16) is a monocyclic monoterpene hydrocarbon naturally synthesized in many plants through the cyclisation of geranyl pyrophosphate by a monoterpene synthase. It constitutes one of the most abundant monocyclic monoterpenes in the plant kingdom, being found in more tan 300 essential oils and principally in Citrus spp. (30-98%). The high availability in nature together with its proved safety, make it widely exploitable in health, as flavoring agent and adjuvant in food and beverage industries, as well as in cosmetic’s for the formulation of perfumes and other personal hygiene products. In particular, this compound has been proven to possess a valuable potential as sustainable replacement to synthetic pesticides and food preservatives. To successfully use limonene in a greener agri-food industry, its preservation has become a top concern for manufacturers. In general, encapsulation conserves and protects limonene from outside aggressions, but also allows its controlled release as well as enchances its low water solubility, which can be critical for the target applications, together with other parameters, such as scalability, low cost and availability.
  • 1.7K
  • 24 Feb 2022
Topic Review
Ferromagnetic
Ferromagnetism is a phenomenon whereby a substance can become a permanent magnet or strongly reacts to a magnetic field. 
  • 1.7K
  • 27 Apr 2022
Topic Review
Tiny-YOLO-Based CNN Architecture for Applications in Human Detection
Human detection is a special application of object recognition and is considered one of the greatest challenges in computer vision. It is the starting point of a number of applications, including public safety and security surveillance around the world. Human detection technologies have advanced significantly due to the rapid development of deep learning techniques. Convolutional neural networks (CNNs) have become quite popular for tackling various problems, among which includes object detection.
  • 1.7K
  • 14 Oct 2022
Topic Review
Balloon Satellite
A balloon satellite (also occasionally referred to as a "satelloon", which is a trademarked name owned by Gilmore Schjeldahl's G.T. Schjeldahl Company) is a satellite that is inflated with gas after it has been put into orbit.
  • 1.7K
  • 17 Oct 2022
Topic Review
Miscarriage and Grief
Miscarriage and grief are both an event and subsequent process of grieving that develops in response to a miscarriage. Almost all those experiencing a miscarriage experience grief. This event is often considered to be identical to the loss of a child and has been described as traumatic. But the vast majority of those who have suffered both will tell you they are nothing alike. Losing a child is in a category of its own when it comes to grief. "Devastation" is another descriptor of miscarriage. Grief differs from the emotion sadness. Sadness is an emotion along with grief, on the other hand, is a response to the loss of the bond or affection was formed and is a process rather than one single emotional response. Grief is not equivalent to depression. Grief also has physical, cognitive, behavioral, social, cultural, and philosophical dimensions. Bereavement and mourning refer to the ongoing state of loss, and grief is the reaction to that loss. Emotional responses may be bitterness, anxiety, anger, surprise, fear, and disgust and blaming others; these responses may persist for months. Self-esteem can be diminished as another response to miscarriage. Not only does miscarriage tend to be a traumatic event, women describe their treatment afterwards to be worse than the miscarriage itself. A miscarriage can often be "heart-breaking". A miscarriage can affect the women, husband, partner, siblings, grandparents, the whole family system and friends. Almost all those experiencing a miscarriage go through a grieving process. Serious emotional impact is usually experienced immediately after the miscarriage. Some may go through the same loss when an ectopic pregnancy is terminated. In some, the realization of the loss can take weeks. Providing family support to those experiencing the loss can be challenging because some find comfort in talking about the miscarriage while others may find the event painful to discuss. The father of the baby can have the same sense of loss. Expressing feelings of grief and loss can sometimes be harder for men. Some women are able to begin planning their next pregnancy after a few weeks of having the miscarriage. For others, planning another pregnancy can be difficult. Organizations exist that provide information and counselling to help those who have had a miscarriage. Some women have a higher risk of developing prolonged grief and complicated grief than others. A factor that can affect grief for men is finding help in an environment that is traditionally women-focused for maternity care and support.
  • 1.7K
  • 25 Oct 2022
Topic Review
Conservative Democracy
Conservative democracy (Turkish: muhafazakâr demokrasi) is a label coined by the ruling Justice and Development Party (AKP) of Turkey to describe Islamic democracy. Forming as a modernist breakaway party from former Islamist movements, the AKP's conservative democratic ideology has been described as a departure from or moderation of Islamic democracy and the endorsement of more secular and democratic values. The electoral success and the neo-Ottoman foreign policy of the AKP that aims to broaden Turkey's regional influence has led to the party's conservative democratic ideals to be mirrored in other countries, such as by the Justice and Development Party in Morocco and the Ennahda Movement in Tunisia. In its broadest sense, the term conservative democracy highlights the compatibility of Islam with democracy, a Western-oriented foreign policy, neoliberal economics and secularism within government. Since the view has been reflected in several economic, foreign, domestic and social policy initiatives, the term conservative democracy has been referred to as a floating signifier that encompasses a broad coalition of ideas. In contrast, and because of its broad definition, the term has also been accused of being a red herring designed to conceal a hidden Islamist agenda but maintain public support. The main ideals of conservative democracy are best identified when they are compared to the Islamist ideology advocated by the AKP's preceding parties. A substantial contrast between the two exist, for example, on their position regarding the European Union, Israel, the United States , economic policy, and to a lesser extent social policy.
  • 1.7K
  • 31 Oct 2022
Topic Review
DNA Cryptography
Encryption, also known as cryptography, is the most widely used approach to achieve confidentiality and verify integrity. It is also the main way to secure governments, social data and personal transactions, since all of these entities require a great amount of protection against known/unknown attacks and threats.
  • 1.7K
  • 05 Jan 2023
Topic Review
Visual Dysfunction in Parkinson’s Disease
Non-motor symptoms in Parkinson’s disease (PD) include ocular, visuoperceptive, and visuospatial impairments, which can occur as a result of the underlying neurodegenerative process. Ocular impairments can affect various aspects of vision and eye movement. Thus, patients can show dry eyes, blepharospasm, reduced blink rate, saccadic eye movement abnormalities, smooth pursuit deficits, and impaired voluntary and reflexive eye movements. Furthermore, visuoperceptive impairments affect the ability to perceive and recognize visual stimuli accurately, including impaired contrast sensitivity and reduced visual acuity, color discrimination, and object recognition. Visuospatial impairments are also remarkable, including difficulties perceiving and interpreting spatial relationships between objects and difficulties judging distances or navigating through the environment. Moreover, PD patients can present visuospatial attention problems, with difficulties attending to visual stimuli in a spatially organized manner. Moreover, PD patients also show perceptual disturbances affecting their ability to interpret and determine meaning from visual stimuli. And, for instance, visual hallucinations are common in PD patients.
  • 1.7K
  • 15 Aug 2023
Topic Review
Large-Scale CFB Boiler Engineering Tests and Measurement Methods
Circulating fluidized bed (CFB) boilers offer a technically viable and environmentally friendly means for the clean and efficient utilization of solid fuels. However, the complex gas–solid two-phase flow processes within them have hindered a thorough resolution of prediction issues related to coupled combustion, heat transfer, and pollutant generation characteristics. To address the deficiencies in scientific research, meet the practical operational needs of CFB boilers, and comply with new carbon emission policies, conducting full-scale field tests on large-scale CFB boilers is needed, so that the complex gas–solid flow, combustion, and heat transfer mechanisms in the furnace can be comprehended.
  • 1.7K
  • 28 Feb 2024
Topic Review Peer Reviewed
The Health Impact of Fast Fashion: Exploring Toxic Chemicals in Clothing and Textiles
The fashion industry is widely recognized for its environmental challenges, but the health impacts related to textile toxicity remain significantly underexplored. Beyond the well-known issues of pollution and resource depletion, modern clothing often harbors a hidden threat: hazardous chemicals embedded within fabrics. These include dyes containing heavy metals, antimicrobial agents that foster bacterial resistance, and synthetic fibers that release microplastics. Unlike environmental discussions, the dialogue around the direct and long-term health effects of these substances is still limited. This entry addresses critical yet often-overlooked concerns, such as how chemicals in textiles contribute to chronic skin conditions, hormonal disruptions, and even carcinogenic risks. It also examines the proliferation of bacteria in synthetic garments, leading to dermatological infections and rapid fabric degradation. Furthermore, the globalized nature of production masks the contamination risks transferred from producer to consumer countries. Through an interdisciplinary approach, this entry highlights the urgent need for integrating scientific innovation, stringent regulation, and consumer awareness to mitigate health hazards in fashion. It calls for the adoption of safer textile technologies, sustainable materials, and transparent production practices, paving the way for a fashion future that prioritizes human health as much as environmental sustainability.
  • 1.7K
  • 19 Jun 2025
Topic Review
Enhancement of Anaerobic Digestion Process with Biochar
Anaerobic digestion (AD) process is usually limited by factors such as process inefficiencies from substrate-induced instability, poor quality digestate, and poor management of effluent and emissions. Biochar, which is a highly porous carbonaceous material produced from the pyrolysis of biomass is an affordable accelerant that can be used to improve the efficiency of the AD process. Biochar has large specific surface area (SSA), high porosity, and abundant surface functional groups which allows for adsorption and ion exchange thereby removes free ammonia and ions and curbs their deleterious effect on the AD process. The performance of biochar in the AD process usually depends on its properties which are a function of pyrolysis conditions and the type of feedstock used in its production. However, these conditions/properties are not well understood. Additionally, the various mechanisms through which biochar enhances the performance of anaerobic digestion process. Accordingly, this research provides valuable insights into the utilization of biochar as an accelerator to enhance the AD process, addressing crucial factors such as optimal pyrolysis conditions, biochar dosage, and feedstock selection. Additionally, it delves into the mechanisms through which biochar positively influences the AD process, particularly by influencing microbial communities, reducing VFA levels, and mitigating the negative effects of ammonia. The research also highlights areas for further research in applying biochar for anaerobic digestion.
  • 1.7K
  • 24 May 2023
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