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Topic Review
The Effect of Perceptions on Tourism
Today, tourism plays an important role in the economic and financial development of countries, and its impact is greater than ever. Therefore, for sustainable economic and financial growth and well-planned development, public and private investments should be directed to areas of priority tourism development. 
  • 1.8K
  • 12 Jul 2022
Topic Review
Deep and Meaningful E-Learning
Deep and meaningful e-learning should be an essential outcome of quality education.
  • 1.8K
  • 25 Mar 2021
Topic Review
Xanthomonas campestris
Xanthomonas campestris pv. campestris (Xcc) is a Gram-negative, aerobic, vascular, and motile bacterium with a single flagellum, which causes the disease identified as black rot in Brassica crops.
  • 1.8K
  • 30 Aug 2021
Topic Review
Climate-Smart Agriculture of Hungarian Agribusiness
Climate change and agriculture interact with each other in many ways and have a complex impact. The agriculture sector needs to be prepared to adapt to the expected effects of climate change, and emphasis must be placed on prevention to achieve emission reduction targets. The research explores the current situation in the agricultural sector, the risks of climate change, as well as the Climate-Smart Agriculture (CSA) solutions that appear at Hungarian agribusiness. Examining the climate innovation activities of farms shows a coherence of the practical application. The research is based on a questionnaire survey of Hungarian agribusiness and the country directorates of the National Chamber of Agriculture. The investigation confirmed that although farmers are susceptible to Agri-Innovation, they only partly exploit the potential of digitalization. For agriculture, the spread of agricultural digitalization and technology transfer is an excellent opportunity to increase agricultural production, maintain and improve its market position, and increase its digital maturity, which can also enhance the integration of climate innovation and sustainability aspects supporting the green economic development.
  • 1.8K
  • 24 Sep 2021
Topic Review
Inflammatory Bowel Disease Treatments
Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammation of the gastrointestinal tract with a highly heterogeneous presentation. It has a relapsing and remitting clinical course that necessitates lifelong monitoring and treatment. Although the availability of a variety of effective therapeutic options including immunomodulators and biologics (such as TNF, CAM inhibitors) has led to a paradigm shift in the treatment outcomes and clinical management of IBD patients, some patients still either fail to respond or lose their responsiveness to therapy over time.
  • 1.8K
  • 05 Jul 2022
Topic Review
Net Primary Productivity of Forest Ecosystems in Karst
The net primary productivity (NPP) of forest ecosystems is an important factor for understanding the carbon budget of forest ecosystems. There have been many studies on the spatialtemporal characteristics and change trends of the NPP in southwest areas based on observation and remote sensing models. With serious water and soil loss and rocky desertification the environment has become sensitive and fragile, so karst areas have become one of the most vulnerable ecological areas in China. The delicate ecological environment and frequent human activities make it difficult to restore the vegetation in the karst area once it is damaged; the damage affects ecosystem services and other functions and leads to fluctuations in the carbon sequestration and sink enhancement capacity in the area. Therefore, combining, analyzing and summarizing the research regarding forest NPP in karst areas is of great importance for improving the estimation accuracy and assessment of carbon storage and sequestration potential in this area.
  • 1.8K
  • 14 Sep 2022
Topic Review
Millennium Falcon
Template:Infobox fictional spacecraft The Millennium Falcon is a fictional starship in the Star Wars franchise. The modified YT-1300 Corellian light freighter is primarily commanded by Corellian smuggler Han Solo (Harrison Ford) and his Wookiee first mate, Chewbacca (Peter Mayhew). Designed by the Corellian Engineering Corporation (CEC), the highly modified YT-1300 is durable, modular, and is stated as being the second-fastest vessel in the Star Wars canon. The Millennium Falcon first appears in Star Wars (1977), and subsequently in The Empire Strikes Back (1980), Return of the Jedi (1983), Revenge of the Sith (2005), The Force Awakens (2015), The Last Jedi (2017), and Solo: A Star Wars Story (2018). Additionally, the Falcon appears in a variety of Star Wars expanded universe materials, including books, comics, and games; James Luceno's novel Millennium Falcon focuses on the titular ship. It also appears in the 2014 animated film The Lego Movie in Lego form, with Billy Dee Williams and Anthony Daniels reprising their roles of Lando Calrissian and C-3PO, and Keith Ferguson voicing Han Solo.
  • 1.8K
  • 09 Oct 2022
Topic Review
Polyphenols and Muscle Atrophy
Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced protein synthesis/accelerated protein degradation. Various conditions, such as denervation, disuse, ageing, chronic diseases, heart disease, obstructive lung disease, diabetes, renal failure, AIDS, sepsis, cancer, and steroidal medications, can cause muscle atrophy. Mechanistically, inflammation, oxidative stress, and mitochondrial dysfunction are among the major contributors to muscle atrophy, by modulating signalling pathways that regulate muscle homeostasis. To prevent muscle catabolism and enhance muscle anabolism, several natural and synthetic compounds have been investigated. Recently, polyphenols (i.e., natural phytochemicals) have received extensive attention regarding their effect on muscle atrophy because of their potent antioxidant and anti-inflammatory properties. Numerous in vitro and in vivo studies have reported polyphenols as strongly effective bioactive molecules that attenuate muscle atrophy and enhance muscle health. 
  • 1.8K
  • 08 Sep 2021
Topic Review
The Role of EREG/EGFR Pathway in Tumor Progression
Aberrant activation of the epidermal growth factor receptor (EGFR/ERBB1) by erythroblastic leukemia viral oncogene homolog (ERBB) ligands contributes to various tumor malignancies, including lung cancer and colorectal cancer (CRC). Epiregulin (EREG) is one of the EGFR ligands and is low expressed in most normal tissues. Elevated EREG in various cancers mainly activates EGFR signaling pathways and promotes cancer progression.
  • 1.8K
  • 13 Dec 2021
Topic Review
Iron Deficiency in Heart Failure
Iron is an essential micronutrient for a myriad of physiological processes in the body beyond erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure (HF), with a prevalence reaching up to 59% even in non-anaemic patients. ID impairs exercise capacity, reduces the quality of life, increases hospitalisation rate and mortality risk regardless of anaemia. Intravenously correcting ID has emerged as a promising treatment in HF as it has been shown to alleviate symptoms, improve quality of life and exercise capacity and reduce hospitalisations. However, the pathophysiology of ID in HF remains poorly characterised. Recognition of ID in HF triggered more research with the aim to explain how correcting ID improves HF status as well as the underlying causes of ID in the first place. In the past few years, significant progress has been made in understanding iron homeostasis by characterising the role of the iron-regulating hormone hepcidin, the effects of ID on skeletal and cardiac myocytes, kidneys and the immune system.
  • 1.8K
  • 11 Apr 2022
Topic Review
China Automotive Firms' Efficiency Evaluation
DEA (Data Envelopment Analysis), as a methodology for the efficiency evaluation of Decision-Making Units (DMUs) with multiple inputs and outputs, is widely used in various areas. The basic idea of DEA is to fit a non-parametric efficient production frontier with DMUs and measure the efficiency relative to the best-performance observations in the sample. In this paper, the China’s listed firms in the automotive industry are seen as the DMUs, and our goal is to measure the efficiency of each DMU and identity the ones that use the inputs more efficiently than the others that have resources over-utilized, namely, the firms can reduce the inputs while the outputs remains constant (input-oriented) rather than the firms can increase the outputs while their inputs remains constant (output-oriented). Therefore, the input-oriented model of DEA is appropriate for our research.
  • 1.8K
  • 06 Mar 2021
Topic Review
Homocysteine and Mitochondria
Elevated concentration of homocysteine (Hcy) in the blood plasma, hyperhomocysteinemia (HHcy), has been implicated in various disorders, including cardiovascular and neurodegenerative diseases. Accumulating evidence indicates that pathophysiology of these diseases is linked with mitochondrial dysfunction. Mitochondria are essential for maintaining cellular homeostasis and function. The interaction between Hcy and mitochondria is complex and reactive oxygen species (ROS) seem to be important mediators of Hcy effects. Although oxidative damage to mitochondria is frequently demonstrated under HHcy, Hcy may have also beneficial effects on mitochondrial function and cell viability.
  • 1.8K
  • 11 Nov 2020
Topic Review
Biostimulants in Plant
Adverse environmental conditions due to climate change, combined with declining soil fertility, threaten food security. Modern agriculture is facing a pressing situation where novel strategies must be developed for sustainable food production and security. Biostimulants, conceptually defined as non-nutrient substances or microorganisms with the ability to promote plant growth and health, represent the potential to provide sustainable and economically favorable solutions that could introduce novel approaches to improve agricultural practices and crop productivity. Current knowledge and phenotypic observations suggest that biostimulants potentially function in regulating and modifying physiological processes in plants to promote growth, alleviate stresses, and improve quality and yield. 
  • 1.8K
  • 23 Jan 2021
Topic Review
Polyhydroxyalkanoates (PHAs)
Polyhydroxyalkanoates (PHAs) are promising biodegradable and biocompatible polymers that can be obtained through microbial fermentation of agro-industrial byproducts, e.g., milk and cheese whey by using both microbial consortia and pure bacterial cultures.
  • 1.8K
  • 02 Dec 2021
Topic Review
Design of Sustainable Flexible Pavement
The conventional methodologies for the design of flexible pavements are not adequate in providing solutions that meet the diverse sustainability challenges. Therefore, developing new methodologies and frameworks for the design of flexible pavement has become a priority for most highway agencies. On the other hand, there is no sound sustainable flexible pavement framework at the design phase that considers the key engineering performance, environmental impact, and economic benefits of sustainability metrics. Hence, premature failure of flexible pavements has become a common problem leading to a growing demand for sustainable pavement. Pavement engineers need to have access to tools that permit them to design flexible pavements capable of providing sustainable solutions under various complex scenarios and uncertainties.
  • 1.8K
  • 10 Jan 2022
Topic Review
Laxogenin C
Laxogenin C (LGC) is a natural spirostanol deriving from plant hormone which has shown anti-inflammatory, antibacterial, and growth-regulating activities.
  • 1.8K
  • 12 Apr 2022
Topic Review
PGPR Augmentation in Plants under Drought Stress
Drought stress is a major abiotic stress that significantly affects agricultural productivity every year as the plants undergo several morphological, biochemical, and physiological modifications, such as repressed root and shoot growth, reduced photosynthesis and transpiration rate, excessive production of reactive oxygen species (ROS), osmotic adjustments, and modified leaf senescence regulating and stress signaling pathways. Such modifications may permanently damage the plants; therefore, mitigation strategies must be developed. The use of drought-resistant crop cultivars is more expensive and labor-intensive with few advantages. However, exploiting plant growth promoting rhizobacteria (PGPR) is a proven alternative with numerous direct and indirect advantages.
  • 1.8K
  • 21 Sep 2022
Topic Review
Individual and Political Action on Climate Change
Individual and political action on climate change can take many forms. Many actions aim to build social and political support to limit, and subsequently reduce, the concentration of greenhouse gases (GHGs) in the atmosphere, with the goal of mitigating climate change. Other actions seek to address the ethical and moral aspects of climate justice, especially with regard to the anticipated unequal impacts of climate change adaptation.
  • 1.8K
  • 31 Oct 2022
Topic Review
Photometry
Photometry, from Greek photo- ("light") and -metry ("measure"), is a technique used in astronomy that is concerned with measuring the flux or intensity of light radiated by astronomical objects. This light is measured through a telescope using a photometer, often made using electronic devices such as a CCD photometer or a photoelectric photometer that converts light into an electric current by the photoelectric effect. When calibrated against standard stars (or other light sources) of known intensity and colour, photometers can measure the brightness or apparent magnitude of celestial objects. The methods used to perform photometry depend on the wavelength region under study. At its most basic, photometry is conducted by gathering light and passing it through specialized photometric optical bandpass filters, and then capturing and recording the light energy with a photosensitive instrument. Standard sets of passbands (called a photometric system) are defined to allow accurate comparison of observations. A more advanced technique is spectrophotometry that is measured with a spectrophotometer and observes both the amount of radiation and its detailed spectral distribution. Photometry is also used in the observation of variable stars, by various techniques such as, differential photometry that simultaneously measures the brightness of a target object and nearby stars in the starfield or relative photometry by comparing the brightness of the target object to stars with known fixed magnitudes. Using multiple bandpass filters with relative photometry is termed absolute photometry. A plot of magnitude against time produces a light curve, yielding considerable information about the physical process causing the brightness changes. Precision photoelectric photometers can measure starlight around 0.001 magnitude. The technique of surface photometry can also be used with extended objects like planets, comets, nebulae or galaxies that measures the apparent magnitude in terms of magnitudes per square arcsecond. Knowing the area of the object and the average intensity of light across the astronomical object determines the surface brightness in terms of magnitudes per square arcsecond, while integrating the total light of the extended object can then calculate brightness in terms of its total magnitude, energy output or luminosity per unit surface area.
  • 1.8K
  • 11 Nov 2022
Topic Review
Agro-Industrial Food Waste for Production of Industrial Enzymes
The grave environmental, social, and economic concerns over the unprecedented exploitation of non-renewable energy resources have drawn the attention of policy makers and research organizations towards the sustainable use of agro-industrial food and crop wastes. Enzymes are versatile biocatalysts with immense potential to transform the food industry and lignocellulosic biorefineries. Microbial enzymes offer cleaner and greener solutions to produce fine chemicals and compounds. The production of industrially important enzymes from abundantly present agro-industrial food waste offers economic solutions for the commercial production of value-added chemicals. The recent developments in biocatalytic systems are designed to either increase the catalytic capability of the commercial enzymes or create new enzymes with distinctive properties. The limitations of low catalytic efficiency and enzyme denaturation in ambient conditions can be mitigated by employing diverse and inexpensive immobilization carriers, such as agro-food based materials, biopolymers, and nanomaterials. Moreover, revolutionary protein engineering tools help in designing and constructing tailored enzymes with improved substrate specificity, catalytic activity, stability, and reaction product inhibition. This review discusses the recent developments in the production of essential industrial enzymes from agro-industrial food trash and the application of low-cost immobilization and enzyme engineering approaches for sustainable development.
  • 1.8K
  • 21 Nov 2022
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