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Topic Review
Antimicrobial Stewardship under Global Framework
Antimicrobials are naturally occurring semi-synthetic or synthetic substances that kill or inhibit the replication of microorganisms. Remarkable achievements have been reached in human medicine due to the availability and efficacy of antimicrobials, from the treatment of previously fatal infections to surgical procedures, otherwise impossible. Promoting and supporting antimicrobial stewardship (AMS) at the global, national, and local levels is dependent on building strong supporting pillars. From the Food and Agriculture Organization (FAO) perspective, these pillars are (1) awareness, (2) governance, (3) practices, and (4) surveillance.
  • 515
  • 30 Aug 2022
Topic Review
White Coat in the Domestic Horse
Traits such as shape, size, and color often influence the economic and sentimental value of a horse. Around the world, horses are bred and prized for the colors and markings that make their unique coat patterns stand out from the crowd. The underlying genetic mechanisms determining the color of a horse’s coat can vary greatly in their complexity.
  • 514
  • 05 Mar 2024
Topic Review
Link between Gastrointestinal Microbiome and Neurologic Injury
Communication between the enteric nervous system (ENS) of the gastrointestinal (GI) tract and the central nervous system (CNS) is vital for maintaining systemic homeostasis. Intrinsic and extrinsic neurological inputs of the gut regulate blood flow, peristalsis, hormone release, and immunological function. The health of the gut microbiome plays a vital role in regulating the overall function and well-being of the individual. Microbes release short-chain fatty acids (SCFAs) that regulate G-protein-coupled receptors to mediate hormone release, neurotransmitter release (i.e., serotonin, dopamine, noradrenaline, γ-aminobutyric acid (GABA), acetylcholine, and histamine), and regulate inflammation and mood. Further gaseous factors (i.e., nitric oxide) are important in regulating inflammation and have a response in injury. 
  • 513
  • 04 Mar 2022
Topic Review
Amino Acids Biostimulants and Protein Hydrolysates
The effects of different types of biostimulants on crops include improving the visual quality of the final products, stimulating the immune systems of plants, inducing the biosynthesis of plant defensive biomolecules, removing heavy metals from contaminated soil, improving crop performance, reducing leaching, improving root development and seed germination, inducing tolerance to abiotic and biotic stressors, promoting crop establishment and increasing nutrient-use efficiency. Protein hydrolysates are mixtures of polypeptides and free amino acids resulting from enzymatic and chemical hydrolysis of agro-industrial protein by-products obtained from animal or plant origins, and they are able to alleviate environmental stress effects, improve growth, and promote crop productivity. Amino acids involve various advantages such as increased yield and yield components, increased nutrient assimilation and stress tolerance, and improved yield components and quality characteristics.
  • 513
  • 07 Mar 2024
Topic Review
Lα,25-(OH)2D3 on Osteoclastogenesis
The active form of vitamin D, 1α,25-(OH)2D3, not only promotes intestinal calcium absorption, but also regulates the formation of osteoclasts (OCs) and their capacity for bone mineral dissolution. Gal-3 is a newly discovered bone metabolic regulator involved in the proliferation, differentiation, and apoptosis of various cells.
  • 512
  • 29 Mar 2022
Topic Review
Shoulder Lesions' Influence on Sow Behavior
Some sows are known to develop shoulder lesions after giving birth, yet the pattern of development and healing as well as the welfare implications of these lesions is not well-understood. This study found that the size of the lesion when first noticed was related to the duration that the lesion was present and to the maximum size of the lesion before healing. This information has the potential to help guide the treatment of these animals and reduce the severity of their lesions. We monitored these sows throughout lactation and during gestation and found that the only significant behavioral difference between the sows that did and did not have lesions was that the sows without lesions were more likely to change their posture more frequently. We believe this means that more frequent posture changes may have a protective effect against lesion development. Together, the results of this study have added to our understanding of how long it takes these lesions to heal and reveal insight into the lack of behavioral alterations in sows with such lesions. 
  • 511
  • 20 Jan 2022
Topic Review
Asian Form of Huanglongbing
The Asian citrus psyllid (ACP), Diaphorina citri Kuwayama, transmits ‘Candidatus Liberibacter asiaticus’ (CLas), a phloem-limited bacterium associated with the severe Asian form of huanglongbing (HLB), and the most destructive disease of citrus. The pathogen and the psyllid, both of South Asian origin, are now widespread in citrus regions of Asia and the Americas. There is no cure for the disease. Application of synthetic pesticides, in some instances more frequently than fortnightly, to minimize incidence of ACP in citrus orchards, has not prevented inevitable impacts of the disease in regions of Asia where CLas is present. Despite the inevitable spread of the disease, significant progress has been made in Sarawak since the mid-1990s towards effectively implementing integrated pest management (IPM) programs for stemming the impact of the disease and detrimental consequences of over-reliance on synthetic pesticides. Growers are encouraged to plant pathogen-free trees, remove diseased trees, monitor incidence of the psyllid, and to use pesticides judiciously to reduce their detrimental impacts on natural enemies. Knowledge has been enhanced through research on seasonal incidence of the psyllid, use of mineral oils, development of protocols and iodine–starch test kits for detecting infected trees, PCR for confirming the presence of CLas in symptomatic leaves, methods for monitoring incidence the psyllid, and training extension staff and growers. However, major impediments to increasing the average longevity of trees beyond <5 years in poorly managed orchards, based on marcotting (air layering), and >12 years in well-managed orchards, based on pathogen-free trees, still need to be addressed. These include grower knowledge, marcotting, aggressive marketing of synthetic pesticides, high prices of mineral oils, spray application procedures, and better reliance on natural enemies of the psyllid.
  • 511
  • 15 Nov 2022
Topic Review
Treatment for Itch in Atopic Dermatitis
This entry briefly describes the recent drugs for the treatment of atopic itch.
  • 510
  • 25 Nov 2021
Topic Review
Types and Applications of Unconventional Feed
Unconventional feed, which is abundant in China, contains anti-nutritional factors and toxins; however, these can be greatly reduced with microbial fermentation, thus improving the nutrient content of the feed, enhancing animal appetites, and ultimately significantly improving the intestinal health and growth performance of animals. When oxidative stress occurs, fermented feed can effectively reduce the damage caused by stress to the gastrointestinal tract, accelerate the removal of gastrointestinal abnormalities, improve the ability to resist intestinal stress, and ensure the efficient production of animals. 
  • 510
  • 11 Mar 2024
Topic Review
VGLUT3+ Neurons in Hippocampal Activity and Behaviour
Neurons using glutamate as a neurotransmitter can be characterised by vesicular glutamate transporters (VGLUTs). Among the three subtypes, VGLUT3 is often co-localise with other “classical” neurotransmitters and can modulate their release. Its contribution to sensory processes (including seeing, hearing, and mechanosensation) is well characterised. However, its involvement in learning and memory can only be assumed based on its prominent hippocampal presence. Beside local VGLUT3 positive network hippocampus gets innervation from the median raphe. This hippocampal glutamatergic network plays a pivotal role in several important processes (e.g., learning and memory, emotions, epilepsy, cardiovascular regulation). 
  • 509
  • 24 Feb 2022
Topic Review
Global Navigation Satellite Systems in Precision Agriculture
Global Navigation Satellite Systems (GNSS) in precision agriculture (PA) represent a cornerstone for field mapping, machinery guidance, and variable rate technology.
  • 509
  • 26 Jul 2023
Topic Review
Nitrogen Management
Nitrogen (N) management remains a global challenge for the sustainability of diversified farming systems. Field crops are often over-supplied with nitrogen by farmers aiming to high productivity. Although the increase of nitrogen rates leads in many instances to high yields, degree of effectiveness for nitrogen use remains low. Urease and nitrification inhibitors are technologies which have been present in the fertilizers market at least 50 years. Inhibitors exploitation ensures long-term nitrogen release and improved N-uptake by plants and N-storage in seeds and silage. Avail of inhibitors, such as the decline of nitrogen leaching in form of NO3−, reduction of emissions in NH3 form, and rise of yield, are some of the desirable attributes that are derived from their integration in fertilization schedules. This review reports the evaluation of applied nitrogen, with inhibitors, and field crops based on nitrogen indices. The examined N-indicators include Nitrogen use efficiency (NUE), Nitrogen Utilization Efficiency (NUtE,) Nitrogen Agronomic Efficiency (NAE), Nitrogen Harvest Index (NHI), and N uptake.
  • 508
  • 01 Apr 2021
Topic Review
Role of Extracellular Vesicles in Osteoporosis
As an insidious metabolic bone disease, osteoporosis plagues the world, with high incidence rates. Patients with osteoporosis are prone to falls and becoming disabled, and their cone fractures and hip fractures are very serious, so the diagnosis and treatment of osteoporosis is very urgent. Extracellular vesicles (EVs) are particles secreted from cells to the outside of the cell and they are wrapped in a bilayer of phospholipids. According to the size of the particles, they can be divided into three categories, namely exosomes, microvesicles, and apoptotic bodies. The diameter of exosomes is 30–150 nm, the diameter of microvesicles is 100–1000 nm, and the diameter of apoptotic bodies is about 50–5000 nm. EVs play an important role in various biological process and diseases including osteoporosis.
  • 508
  • 22 Mar 2022
Topic Review
Pain Relief for Livestock Husbandry Procedures
A livestock pain relief innovation in Australia in 2005 that led to an awakening of on-farm pain welfare management, was the development of a ‘spray and stay’ topical anaesthesia and antiseptic wound formulation (topical anaesthetic formulation (TAF); Tri-Solfen®, Medical Ethics, Australia) for use during mulesing in sheep. This product, when applied to wounds, rapidly alleviates pain through blockage of nociception, ablates hyperalgesia, minimises bleeding and provides antisepsis with reduced need for antimicrobial cover during healing. With a rapid onset and prolonged duration, the readily observable clinical efficacy commenced a transformational ‘welfare revolution’ in Australian livestock agricultural attitudes and practices with over 120million animals now treated. On application, the TAF forms a long-lasting bio-compatible barrier over the wound, creating its own intrinsic analgesic properties and diminishing the risk of biofilm formation. The TAF acts as a slow-release carrier for the actives, including the two local anaesthetics, lidocaine hydrochloride (5% w/w) and bupivacaine hydrochloride (0.5% w/w), the antiseptic cetrimide (0.5% w/w), in addition to the vasoconstrictor adrenaline acid tartrate (0.00451% w/w) that minimise vasodilation and bleeding, preventing systemic absorption and risk of toxicity. The TAF keeps the actives in contact with the wound tissue, creating synergies that prolong the analgesia well beyond the expected duration of action of actives (at least 24 h) and hastening both healing of husbandry wounds and other lesions, especially those induced by epidermal viral infections including Foot-and-Mouth Disease virus.
  • 508
  • 11 Oct 2022
Topic Review
Steller Sea Lion
The Steller Sea Lion (Eumetopias jubatus) is a charismatic marine mammal found along the coastlines of the North Pacific Ocean. Renowned for its impressive size and distinctive appearance, including thick fur and prominent whiskers, the Steller Sea Lion holds a prominent place in marine ecosystems as a top predator. Despite facing conservation challenges such as habitat degradation and competition with fisheries, these social and intelligent creatures continue to capture the fascination of researchers and wildlife enthusiasts alike.
  • 508
  • 08 Mar 2024
Topic Review
Potential of Flow Cytometric Approaches in Food Industry
Microbial contamination, including the carryover of infectious microbes, is a global public health concern. An alternative technique that serves as a powerful, rapid, and highly sensitive method for the specific and non-specific detection, monitoring, enumeration, and characterization of microorganisms is flow cytometry (FCM).
  • 507
  • 12 Jan 2022
Topic Review
Antimutagenic Plants of Saudi Arabia
Mutagenic complications can cause disease in both present as well as future generations. The disorders are caused by exogenous and endogenous agents that damage DNA beyond the normal repair mechanism. Rapid industrialization and the population explosion have contributed immensely to changes in the environment, leading to unavoidable exposure to mutagens in our daily life. 
  • 506
  • 30 Sep 2021
Topic Review
Organellar Evolution
Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original beneficial function. The organellar function essential for cell survival is, in the end, the result of organellar evolution, particularly losses of redundant metabolic pathways present in both the host and endosymbiont, followed by a gradual distribution of metabolic functions between the organelle and host.
  • 506
  • 19 Jan 2022
Topic Review
Reversible Methylation of N6-Methyladenosine in Plant Virus Infection
N6-methyladenosine (m6A) is the most prevalent modification in the mRNAs of many eukaryotic species. The abundance and effects of m6A are determined by dynamic interactions between its methyltransferases (“writers”), demethylases (“erasers”), and binding proteins (“readers”). It has been indicated that there is a strong correlation between m6A and virus infection in mammals. In the case of plant virus infection, it appears that m6A plays a dual role. On the one hand, m6A acts as a plant immune response induced by virus infection, inhibiting viral replication or translation through methylation of viral genome RNAs. On the other hand, m6A acts as part of an infection strategy employed by plant viruses to overcome the host immune system by interacting with m6A-related proteins. 
  • 506
  • 25 Feb 2022
Topic Review
Quantitative Vitamin A Analysis Approaches
Ensuring that animals receive a well-balanced diet and appropriate feed formulation can significantly enhance animal productivity, improve the quality of their products, and promote better animal welfare. Vitamin A, also known as retinol, is a vital micronutrient crucial for maintaining optimal health and well-being in livestock. It plays a central role in various physiological functions, including immune response regulation, vision maintenance, and cellular differentiation. Consequently, the accurate determination of vitamin A levels in animal feed and premixes is essential for ensuring animal health and production. Beyond preventing deficiencies and associated health issues, it forms the foundation for their overall growth and performance.
  • 506
  • 18 Feb 2024
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