Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Hydrogel-Forming Microneedles
Controlled drug delivery in the oral cavity poses challenges such as bacterial contamination, saliva dilution, and inactivation by salivary enzymes upon ingestion. Microneedles offer a location-specific, minimally invasive, and retentive approach. Hydrogel-forming microneedles (HFMs) have emerged for dental diagnostics and therapeutics. HFMs penetrate the stratum corneum, undergo swelling upon contact, secure attachment, and enable sustained transdermal or transmucosal drug delivery. Commonly employed polymers such as polyvinyl alcohol (PVA) and polyvinyl pyrrolidone are crosslinked with tartaric acid or its derivatives while incorporating therapeutic agents. Microneedle patches provide suture-free and painless drug delivery to keratinized or non-keratinized mucosa, facilitating site-specific treatment and patient compliance. 
  • 1.9K
  • 24 Aug 2023
Topic Review
Cloud Vendor Lock-In
Cloud computing has become an integral part of businesses and personal lives due to its scalability, cost-effectiveness, accessibility, and user-friendliness. Its popularity has led to widespread adoption by people and businesses alike, resulting in significant market growth.
  • 1.9K
  • 05 Feb 2024
Topic Review
Redefining Precision Management of r/r Large B-Cell Lymphoma
The treatment paradigms for patients with relapsed large B-cell lymphoma are expanding. Chimeric antigen receptor technology (CAR-T) has revolutionized the management of these patients. Novel bispecific antibodies and antibody–drug conjugates, used as chemotherapy-free single agents or in combination with other novel therapeutics, have been quickly introduced into the real-world setting. With such a paradigm shift, patients have an improved chance of better outcomes with unpredictable complete remission rates. 
  • 1.9K
  • 21 Jul 2023
Topic Review
Antagonistic Yeasts
Antagonistic yeasts (also known as biocontrol yeasts) are promising substitutes for chemical fungicides in the control of postharvest decay owing to their widespread distribution, antagonistic ability, environmentally friendly nature, and safety for humans.
  • 1.9K
  • 26 Oct 2020
Topic Review
Granulocyte Colony-Stimulating Factor
Granulocyte colony-stimulating factor (G-CSF) is a hematopoetic growth factor that is released in response to infection or inflammation to stimulate hematopoetic stem cells to proliferate and generate colonies of differentiated neutrophils. In the therapeutic setting major applications of administration of recombinant G-CSG include: 1) treatment of cyclic and chronic neutropenias; 2) attenuation of the magnitude and duration of chemotherapy-induced neutropenia in cancer patients and 3) mobilization of hematopoetic progenitor cells into peripheral blood to be harvested for stem cell transplantation.
  • 1.9K
  • 02 Dec 2020
Topic Review
Primary Hyperoxalurias
Primary hyperoxalurias (PHs) are a group of inherited alterations of the hepatic glyoxylate metabolism. PHs classification based on gene mutations parallel a variety of enzymatic defects, and all involve the harmful accumulation of calcium oxalate crystals that produce systemic damage.
  • 1.9K
  • 18 Feb 2021
Topic Review
ICTs for Education during COVID-19
The educational field has experienced a significant variation with the inclusion of information and communication technologies (ICTs), applying a wide range of tools, from drones, for the explanation of theoretical ideas, to virtual learning environments and virtual realities. These tools and multidisciplinary structures have given more flexibility, adaptability, and dynamics to the education system. The educational structures tend to include ICTs with a higher compliance capacity, accessibility, and end-user attractiveness. Additionally, the utilization of virtual realities via mobile devices and headsets is increasing, as they allow the immersion and acquiring of theoretical or practical skills. In mid-2020, the pandemic of COVID-19 forced the higher institutions (HEIs) to include several ICTs and to move to online teaching, trying to guarantee the continuity and quality in their teaching process.
  • 1.9K
  • 22 Jun 2021
Topic Review
Vasopressor-Sparing and Patients with Shock
Vasopressor therapy is to restore organ perfusion so as to limit the risk of multiple organ failure and death.
  • 1.9K
  • 11 Nov 2021
Topic Review
Metal-Organic Frameworks-Based Sensors for Food Safety
Metal-organic frameworks (MOFs) are a class of crystalline porous materials systems structured by using metals linked together by organic bridging ligands.
  • 1.9K
  • 09 Feb 2022
Topic Review
Phenotype Variations in Oculocutaneous Albinism
Oculocutaneous albinism (OCA) is an autosomal recessive syndromic and non-syndromic defect with deficient or a complete lack of the melanin pigment. The characteristics of OCA appears in skin, hair, and eyes with variable degree of pigmentation. Clinical manifestations of OCA include nystagmus, photophobia, reduced visual acuity, hypo-plastic macula, and iris trans-illumination. There are eight OCA types (OCA1–8) documented with non-syndromic characteristics.
  • 1.9K
  • 30 Jun 2022
Topic Review
Chasmataspidid
Chasmataspidids, sometime referred to as chasmataspids, are a group of extinct chelicerate arthropods that form the order Chasmataspidida. Chasmataspidids are probably related to horseshoe crabs (Xiphosura) and/or sea scorpions (Eurypterida), with more recent studies suggest that they form a clade (Dekatriata) with Eurypterida and Arachnida. Chasmataspidids are known sporadically in the fossil record through to the mid-Devonian, with possible evidence suggest that they also present during the late Cambrian. Chasmataspidids are most easily recognised by having an abdomen divided into a short forepart (preabdomen or mesosoma) and a longer hindpart (postabdomen or metasoma) each comprising 4 and 9 segments respectively. There is some debate about whether they form a natural (i.e. monophyletic) group.
  • 1.9K
  • 14 Oct 2022
Topic Review
Organizational Health
Organizations are perceived as having a unique identity by their employees, and this new identity has the potential to influence employee behavior. According to the concept of organizational health, employees are dedicated to their organizations, their roles are defined and valuable, and they experience exceptional performance and a sense of belonging to their work. To build a healthy society, health organizations must be established that are defined by continuity, survival in their environment, adaptation, and upgrading and growing their adaptive potential.
  • 1.9K
  • 07 Oct 2023
Topic Review
Freeze-Drying
 Freeze-dried materials are especially recommended for the production of spices, coffee, dried snacks from fruits and vegetables and food for military or space shuttles, as well as for the preparation of food powders and microencapsulation of food ingredients.
  • 1.9K
  • 14 Jan 2021
Topic Review
Brain Lateralization and Cognitive Capacity
One way to increase cognitive capacity is to avoid duplication of functions on the left and right sides of the brain. There is a convincing body of evidence showing that such asymmetry, or lateralization, occurs in a wide range of both vertebrate and invertebrate species. Each hemisphere of the brain can attend to different types of stimuli or to different aspects of the same stimulus and each hemisphere analyses information using different neural processes. A brain can engage in more than one task at the same time, as in monitoring for predators (right hemisphere) while searching for food (left hemisphere). Increased cognitive capacity is achieved if individuals are lateralized in one direction or the other. The advantages and disadvantages of individual lateralization are discussed. Directional, or population-level, lateralization, which occurs when most individuals in a species have the same direction of lateralization, provides no additional increase in cognitive capacity compared to individual lateralization although directional lateralization is advantageous in social interactions. Strength of lateralization is considered, including the disadvantage of being very strongly lateralized. The role of brain commissures is also discussed with consideration of cognitive capacity. 
  • 1.9K
  • 08 Jul 2021
Topic Review
List of Programs for Point Cloud Processing
This is an overview of programs for processing 3D point clouds from appropriate photos or surveys with laser scanners.
  • 1.9K
  • 17 Nov 2022
Topic Review
Microglia Activation and Noradrenergic System
The nervous system requires immune cells to fight foreign body invasion including the pathogenic infection. This function is accomplished by microglia, which also play many other roles in the central nervous system including elimination of apoptotic cells, synaptic pruning, supporting neuronal survival, clearing debris, etc. Under healthy conditions, cyto-morphologically, microglia possess long thin processes and a small cell body, useful for debris clearance. However, upon exposure to inflammation, it becomes “activated” to function as immune cells of the central nervous system and develop short, thick processes and a larger cell body. They phagocytose the pathogens, release inflammatory mediators, and regulate T-cell activity. A variety of neurotransmitter receptors are expressed on the microglia which facilitate bidirectional communication between neurons and microglia. It has been shown that withdrawal of noradrenaline (NA) is a necessity for generation of rapid eye movement sleep (REMS). It has been proposed that REMS has evolved to maintain NA level in the brain. Further, NA exerts neuromodulatory action on microglia and facilitates immune function of the brain. Thus, REMS modulates immune functions of the brain.
  • 1.9K
  • 29 Dec 2022
Topic Review
Hydrogels for Oral Tissue Engineering
Oral health is crucial to daily life, yet many people worldwide suffer from oral diseases. With the development of oral tissue engineering, there is a growing demand for dental biomaterials. Addressing oral diseases often requires a two-fold approach: fighting bacterial infections and promoting tissue growth. Hydrogels are promising tissue engineering biomaterials that show great potential for oral tissue regeneration and drug delivery.
  • 1.9K
  • 10 May 2023
Topic Review
Microneedle Production
Microneedles (MNs) represent one of the most promising concepts for effective transdermal drug delivery that penetrate the protective skin barrier in a minimally invasive and painless manner. Therefore, different manufacturing methods, not only for MNs but also MN molds, are introduced, which allows for the cost-effective production of MNs for drug and vaccine delivery and even diagnostic/monitoring purposes.
  • 1.9K
  • 25 Oct 2022
Topic Review
Polycystic Ovary Syndrome
The application of metabolomics in searching for the mechanisms of the polycystic ovary syndrome (PCOS) pathophysiology gives a promising insight into the research on PCOS. There is a need to investigate the metabolic pathways, which could be involved in the pathophysiology of PCOS and to find the metabolic markers of this disorder. Metabolomics is a valuable and rapidly expanding tool, enabling the discovery of novel metabolites, which may be the potential biomarkers of metabolic and endocrine disorders. 
  • 1.9K
  • 25 Dec 2020
Topic Review
Artificial Intelligence and Firm Performance
Developments in computer science, robotics, machine learning, and data accumulation have facilitated the application of advanced technologies in businesses. Among the cutting-edge technologies, Artificial Intelligence (AI) has gained growing attention in different sectors of society, industry, and business. The unprecedented novel coronavirus (COVID-19) pandemic has brought massive uncertainty and has negatively impacted health care, economy, population mobility, and numerous industries, including tourism, aviation, manufacturing, education, and other business sectors. The halted production, supply chain disruption, and shrinking customer activity led to a decline in company revenues and negatively affected corporate performance and the world economy.
  • 1.9K
  • 02 Aug 2022
  • Page
  • of
  • 2728
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback