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Topic Review
Fractional-Order Digital Filters
Fractional-order digital filters have developed to provide an alternative solution to higher-order integer-order filters, with increased design flexibility and better performance.
  • 1.9K
  • 21 Sep 2021
Topic Review
Rainfall Measurement by Commercial Microwave Links
As one of the most critical elements in the hydrological cycle, real-time and accurate rainfall measurement is of great significance to flood and drought disaster risk assessment and early warning. Using commercial microwave links (CMLs) to conduct rainfall measure is a promising solution due to the advantages of high spatial resolution, low implementation cost, near-surface measurement, and so on.
  • 1.9K
  • 29 Jun 2022
Topic Review
Practical Echocardiographic Approach of Regurgitant Mitral Valve Assessment
Mitral regurgitation is the second-most frequent valvular heart disease in Europe after degenerative aortic stenosis. The mitral valve is a complex anatomical structure whose physiological functioning relies on the biomechanical properties and structural integrity of its components. Their compromise can lead to mitral valve dysfunction. Assessing its morphology can reveal various normal and abnormal features, which can be associated with deteriorating clinical outcomes. Transthoracic echocardiography is the first diagnosis approach that should be performed to assess the valve disfunction, giving a complete morphological description of the structures, the regurgitant mechanism, and etiology.
  • 1.9K
  • 22 Aug 2022
Topic Review
List of Intel Pentium M Microprocessors
The Pentium M brand refers to single-core 32-bit mobile CPUs codenamed Banias and Dothan, and targeted at the consumer market of mobile computers.
  • 1.9K
  • 19 Oct 2022
Topic Review
Single Molecule Real Time Sequencing
Single molecule real time sequencing (SMRT) is a parallelized single molecule DNA sequencing method. Single molecule real time sequencing utilizes a zero-mode waveguide (ZMW). A single DNA polymerase enzyme is affixed at the bottom of a ZMW with a single molecule of DNA as a template. The ZMW is a structure that creates an illuminated observation volume that is small enough to observe only a single nucleotide of DNA being incorporated by DNA polymerase. Each of the four DNA bases is attached to one of four different fluorescent dyes. When a nucleotide is incorporated by the DNA polymerase, the fluorescent tag is cleaved off and diffuses out of the observation area of the ZMW where its fluorescence is no longer observable. A detector detects the fluorescent signal of the nucleotide incorporation, and the base call is made according to the corresponding fluorescence of the dye.
  • 1.9K
  • 01 Nov 2022
Topic Review
The Double-Tube Heat Exchanger Performance
The double-tube heat exchanger is one of the most common designs of heat exchangers used in commercial and industrial applications. It is the simplest and one in which hot and cold fluids move in same or opposite directions. Various methods are presented to improve a double-tube heat exchanger.  
  • 1.9K
  • 26 Oct 2022
Topic Review
Antidiabetic Properties of Curcumin I
Type 2 diabetes mellitus (T2DM) is a growing metabolic disease characterized by insulin resistance and hyperglycemia. Current preventative and treatment strategies for T2DM and insulin resistance lack in efficacy resulting in the need for new approaches to prevent and manage/treat the disease better. In recent years, epidemiological studies have suggested that diets rich in fruits and vegetables have beneficial health effects including protection against insulin resistance and T2DM. Curcumin, a polyphenol found in turmeric, and curcuminoids have been reported to have antioxidant, anti-inflammatory, hepatoprotective, nephroprotective, neuroprotective, immunomodulatory and antidiabetic properties. Here we are summarizing the existing in vitro studies examining the antidiabetic effects of curcumin.
  • 1.9K
  • 29 Oct 2020
Topic Review
Rural Livelihood Climate Vulnerability
Rural livelihood vulnerability to climate change impacts is one of the major policy challenges for sustainable development. Rural socio-economic systems are different from urban and peri-urban systems because of high dependence on climate sensitive natural resources for livelihood practices, access to which is significantly influenced by context-specific socio-cultural and political properties. Rural livelihood vulnerability, therefore, needs to be understood considering both climatic and non-climatic factors. By articulating the Vulnerability Assessment (VA) Framework and the Sustainable Rural Livelihoods (SRL) Framework into a shared conceptual framing, this entry defines the rural livelihood vulnerability and outlines its assessment process. In so doing, the framing borrows three vulnerability components (i.e., exposure, sensitivity and adaptive capacity) for its structural outline and derives analytical variables from the SRL framework.
  • 1.9K
  • 21 Aug 2020
Topic Review
Osteocyte
Osteocytes are the most abundant bone cells, entrapped inside the mineralized bone matrix. They derive from osteoblasts through a complex series of morpho-functional modifications; such modifications not only concern the cell shape (from prismatic to dendritic) and location (along the vascular bone surfaces or enclosed inside the lacuno-canalicular cavities, respectively) but also their role in bone processes (secretion/mineralization of preosseous matrix and/or regulation of bone remodeling). Osteocytes are connected with each other by means of different types of junctions, among which the gap junctions enable osteocytes inside the matrix to act in a neuronal-like manner, as a functional syncytium together with the cells placed on the vascular bone surfaces (osteoblasts or bone lining cells), the stromal cells and the endothelial cells, i.e., the bone basic cellular system (BBCS). Within the BBCS, osteocytes can communicate in two ways: by means of volume transmission and wiring transmission, depending on the type of signals (metabolic or mechanical, respectively) received and/or to be forwarded. The capability of osteocytes in maintaining skeletal and mineral homeostasis is due to the fact that it acts as a mechano-sensor, able to transduce mechanical strains into biological signals and to trigger/modulate the bone remodeling, also because of the relevant role of sclerostin secreted by osteocytes, thus regulating different bone cell signaling pathways.
  • 1.9K
  • 09 Apr 2021
Topic Review
Environmental Management Strategies in Mining Industry in Chile
Sustainable development in the mining industry is a critical concern for companies because it covers multiple environmental, social, and economic approaches. The principal aim of sustainable development is to find the equilibrium between environmental, social, and economic aspects to maintain the system’s stability. In this sense, defining mining sustainability is a complex task because of the multidimensional definition of sustainability. However, the primary concern of the environmental sustainability of the mining industry is to avoid and reduce environmental impact at different stages of the mining life cycle, where the mining industry needs to anticipate possible negative effects that its operations may generate. The mining industry faces diverse challenges to maintain sustainable production, particularly regarding critical water and energy supplies. As a significant player in the copper mining industry, Chile has become a global reference. The most prevailing strategies involved implementing Environmental Management Systems, which allow organisations to define, implement, and track their specific goals and standards.
  • 1.9K
  • 28 Apr 2022
Topic Review
The Golden Verses of Pythagoras
The Golden Verses of Pythagoras (Greek: Χρύσεα Ἔπη, Chrysea Epê; Latin: Aurea Carmina) are a collection of moral exhortations. They comprise 71 lines written in dactylic hexameter verse and are traditionally attributed to Pythagoras. The exact origins of the Golden Verses are unknown and there are varying opinions regarding their dating. It appears that the verses may have been known as early as the third century BCE but their existence as we know them cannot be confirmed prior to the fifth century CE. The Golden Verses enjoyed great popularity and were widely distributed in late antiquity, being often quoted. Their renown persisted during the medieval ages and into the Renaissance. In 1494 the Neoplatonic Greek scholar Constantine Lascaris published in a famous printed edition of his Grammatica, deliberately, the Golden Verses translated into Latin, thereby bringing them to a widespread audience. The Neoplatonists used the Golden Verses as part of their preparatory program of moral instruction, and a number of Neoplatonic commentaries on the verses are extant. The commentary of the Neoplatonist Hierocles of Alexandria on the Golden Verses was first translated into French by André Dacier (1706) and then into English by Nicholas Rowe (1707); a recent English translation is by Schibli (2002). The most recent scholarly edition of the Golden Verses is by Thom (1994), who supplies a new English translation.
  • 1.9K
  • 20 Oct 2022
Topic Review
The Cancer Imaging Archive (TCIA)
The Cancer Imaging Archive (TCIA) is an open-access database of medical images for cancer research. The site is funded by the National Cancer Institute's (NCI) Cancer Imaging Program, and the contract is operated by the University of Arkansas for Medical Sciences. Data within the archive is organized into collections which typically share a common cancer type and/or anatomical site. The majority of the data consists of CT, MRI, and nuclear medicine (e.g. PET) images stored in DICOM format, but many other types of supporting data are also provided or linked to, in order to enhance research utility. All data are de-identified in order to comply with the Health Insurance Portability and Accountability Act and National Institutes of Health data sharing policies. TCIA resources are intended to support: TCIA is recognized as a recommended repository for Nature Scientific Data, PLOS One, and F1000Research. It is also listed in the Registry of Research Data Repositories.
  • 1.9K
  • 02 Dec 2022
Topic Review
Vetiver Grass (Chrysopogon zizanoides L.) in Phytoremediation
The increase of the global population and the requirement of food production and agricultural development, combined with a lack of water resources, have led to human attention being drawn to unconventional water sources, including saline water and wastewater. Most unconventional water treatment methods are not cost-effective; however, researchers have become interested in the phytoremediation method due to its cost-efficient and eco-friendly removal of many pollutants. Research showed that due to its unique characteristics, vetiver grass can be useful in phytoremediation. 
  • 1.9K
  • 02 Mar 2023
Topic Review
Secondary Metabolites of Endophytic Fungi
Plant–microbe interactions range from symbiotic to pathogenic; in the symbiotic relationship, microbes are called ‘endophytes’. Endophytes are conventionally known as microbes existing in all plant endospheric tissues (roots, shoots, fruits, leaves, flowers, seeds, etc.) without causing harmful consequences to the host plant. These microorganisms are usually more abundant in roots and they can be transferred horizontally and vertically. Particularly, endophytic fungi constitute an extremely large community, reaching up to three million species worldwide. These eukaryotic organisms are known to harbor a large variety of secondary metabolites valuable to mankind, plants and the environment. They constitute an excellent substitute for exploring whole plants, thereby gaining time, facilitating the process of isolation and protecting the ecosystem. The scientific community has approved the excellent roles of the fungal bioactive compounds in several vital fields including medicine, pharmacy, agriculture, industry and bioremediation.
  • 1.9K
  • 23 Jan 2022
Topic Review
Features of Clay Minerals Supporting Carbon Dioxide Capture
Carbon capture is among the most sustainable strategies to limit carbon dioxide emissions, which account for a large share of human impact on climate change and ecosystem destruction. This growing threat calls for novel solutions to reduce emissions on an industrial level. Carbon capture by amorphous solids is among the most reasonable options as it requires less energy when compared to other techniques and has comparatively lower development and maintenance costs. In this respect, the method of carbon dioxide adsorption by solids can be used in the long-term and on an industrial scale. Furthermore, certain sorbents are reusable, which makes their use for carbon capture economically justified and acquisition of natural resources full and sustainable. Clay minerals, which are a universally available and versatile material, are amidst such sorbents. These materials are capable of interlayer and surface adsorption of carbon dioxide.
  • 1.9K
  • 13 Apr 2022
Topic Review
List of Autodidacts
This is a list of notable autodidacts which includes people who have been partially or wholly self-taught.
  • 1.9K
  • 25 Nov 2022
Topic Review
Biological Actions of Curcumin
Curcumin (CCM) is one of the most frequently explored plant compounds with various biological actions such as antibacterial, antiviral, antifungal, antineoplastic, and antioxidant/anti-inflammatory properties. The laboratory data and clinical trials have demonstrated that the bioavailability and bioactivity of curcumin are influenced by the feature of the curcumin molecular complex types. Curcumin has a high capacity to form molecular complexes with proteins (such as whey proteins, bovine serum albumin, β-lactoglobulin), carbohydrates, lipids, and natural compounds (e.g., resveratrol, piperine, quercetin).
  • 1.9K
  • 02 Feb 2023
Topic Review
Technicolor
Technicolor theories are models of physics beyond the Standard Model that address electroweak gauge symmetry breaking, the mechanism through which W and Z bosons acquire masses. Early technicolor theories were modelled on quantum chromodynamics (QCD), the "color" theory of the strong nuclear force, which inspired their name. Instead of introducing elementary Higgs bosons to explain observed phenomena, technicolor models were introduced to dynamically generate masses for the W and Z bosons through new gauge interactions. Although asymptotically free at very high energies, these interactions must become strong and confining (and hence unobservable) at lower energies that have been experimentally probed. This dynamical approach is natural and avoids issues of Quantum triviality and the hierarchy problem of the Standard Model. However, since the Higgs boson discovery at the CERN LHC in 2012, the original models are largely ruled out. Nonetheless, it remains a possibility that the Higgs boson is a composite state. In order to produce quark and lepton masses, technicolor or composite Higgs models have to be "extended" by additional gauge interactions. Particularly when modelled on QCD, extended technicolor was challenged by experimental constraints on flavor-changing neutral current and precision electroweak measurements. The specific extensions of particle dynamics for technicolor or composite Higgs bosons are unknown. Much technicolor research focuses on exploring strongly interacting gauge theories other than QCD, in order to evade some of these challenges. A particularly active framework is "walking" technicolor, which exhibits nearly conformal behavior caused by an infrared fixed point with strength just above that necessary for spontaneous chiral symmetry breaking. Whether walking can occur and lead to agreement with precision electroweak measurements is being studied through non-perturbative lattice simulations. Experiments at the Large Hadron Collider have discovered the mechanism responsible for electroweak symmetry breaking, i.e., the Higgs boson, with mass approximately 125 GeV/c2; such a particle is not generically predicted by technicolor models. However, the Higgs boson may be a composite state, e.g., built of top and anti-top quarks as in the Bardeen–Hill–Lindner theory. Composite Higgs models are generally solved by the top quark infrared fixed point, and may require a new dynamics at extremely high energies such as topcolor.
  • 1.9K
  • 28 Sep 2022
Topic Review
DNA Damage Response in Autoimmunity
The DNA damage response and repair (DDR/R) network, a sum of hierarchically structured signaling pathways that recognize and repair DNA damage, and the immune response to endogenous and/or exogenous threats, act synergistically to enhance cellular defence. On the other hand, a deregulated interplay between these systems underlines inflammatory diseases including malignancies and chronic systemic autoimmune diseases, such as systemic lupus erythematosus, systemic sclerosis, and rheumatoid arthritis. Recent data demonstrate accumulation of endogenous DNA damage in peripheral blood mononuclear cells from these patients, which is related to augmented formation of DNA damage and epigenetically regulated functional abnormalities of fundamental DNA repair mechanisms. Since endogenous DNA damage accumulation has serious consequences for cellular health, including genomic instability and enhancement of an aberrant immune response, these results can be exploited for understanding pathogenesis and progression of systemic autoimmune diseases, as well as for the development of new treatments.
  • 1.9K
  • 03 Nov 2020
Topic Review
Natural Clinoptilolite
Zeolites are ionic conductors and the cation electrical mobility in zeolites depends on their hydration state; consequently, the water adsorption/desorption process can be simply investigated by measuring the temporal evolution of current intensity in samples exposed to an environment with constant humidity or dry air, respectively. According to this kinetic analysis, a mechanism has been formulated for the water adsorption process able to justify the Lagergren pseudo-first-order kinetics observed for adsorption and the first-order kinetics observed for desorption. In this mechanism water molecules are first attract by the electric field of the cations and then they move at cation-framework interface to maximize the hydrogen bond interactions.
  • 1.9K
  • 28 Oct 2020
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