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Topic Review
Self-Congruity of Visitor in Heritage Hotels
Heritage hotels attract a large number of foreign and domestic tourists by offering luxurious experiences while also providing an opportunity to learn about the history, art, culture, tastes, traditions, and sentiments present in various eras in a region’s history. Self-congruity greatly influences the visitor’s emotional experiences; the concept of visitors’ self-congruity should find more attention in heritage tourism. Furthermore, using digital technologies can probably improve the overall tourism experience.
  • 2.0K
  • 09 Jun 2022
Topic Review
Production of Refractory Materials with Silicon Dioxide
Organization of environmentally-friendly production of refractory materials based on the principles of cost-effective use of energy and material resources through use of energy-saving technologies and replacement of natural raw materials with industrial and agricultural waste is gaining relevance. Scientists are increasingly interested in creating high-temperature materials using silica of plant origin. Its source is rice husk, a multi-tonnage waste from rice production. Organo-mineral in its nature, rice husk determines the uniqueness of the structure and properties of the materials obtained from it. Use of this waste allows to produce porous, high-strength silicon carbide refractories with properties corresponding to classical analogs, while benefiting from environmental, economic and technological aspects.
  • 2.0K
  • 05 Sep 2022
Topic Review
Geo-Blocking
Geo-blocking or geoblocking is technology that restricts access to Internet content based upon the user's geographical location. In a geo-blocking scheme, the user's location is determined using Internet geolocation techniques, such as checking the user's IP address against a blacklist or whitelist, GPS queries in the case of a mobile device, accounts, and measuring the end-to-end delay of a network connection to estimate the physical location of the user. The result of this check is used to determine whether the system will approve or deny access to the website or to particular content. The geolocation may also be used to modify the content provided, for example, the currency in which goods are quoted, the price or the range of goods that are available, besides other aspects. The term is most commonly associated with its use to restrict access to premium multimedia content on the Internet, such as films and television shows, primarily for copyright and licensing reasons. There are other uses for geo-blocking, such as blocking malicious traffic or to enforce price discrimination, location-aware authentication, fraud prevention, and online gambling (where gambling laws vary by region).
  • 2.0K
  • 04 Nov 2022
Topic Review
Cross-Race Effect
The cross-race effect (sometimes called cross-race bias, other-race bias or own-race bias) is the tendency to more easily recognize faces that are most familiar. A study was made which examined 271 real court cases. In photographic line-ups, 231 witnesses participated in cross-race versus same-race identification. In cross-race lineups, only 45% were correctly identified versus 60% for same-race identifications. In social psychology, the cross-race effect is described as the "ingroup advantage". In other fields, the effect can be seen as a specific form of the "ingroup advantage" since it is only applied in interracial or inter-ethnic situations, whereas "ingroup advantage" can refer to mono-ethnic situations as well. Deeper study of the cross-race effect has also demonstrated two types of processing for the recognition of faces: featural and holistic. It has been found that holistic processing (which occurs beyond individual parts of the face) is more commonly used in same-race situations, but there is an experience effect, which means that as a person gains more experience with those of a particular race, he or she will begin to use more holistic processing. Featural processing is much more commonly used with an unfamiliar stimulus or face.
  • 2.0K
  • 16 Nov 2022
Topic Review
Concepts of Rural Tourism and Farm Tourism
The analysis of environmental, social, and economic factors as vectors for the sustainable development of farm tourism is introduced.
  • 2.0K
  • 11 Sep 2023
Topic Review
TRPV1
Intracellular calcium (Ca2+) concentration ([Ca2+]i) is a key determinant of cell fate and is implicated in carcinogenesis. Membrane ion channels are structures through which ions enter or exit the cell, depending on the driving forces. The opening of transient receptor potential vanilloid 1 (TRPV1) ligand-gated ion channels facilitates transmembrane Ca2+ and Na+ entry, which modifies the delicate balance between apoptotic and proliferative signaling pathways. Proliferation is upregulated through two mechanisms: (1) ATP binding to the G-protein-coupled receptor P2Y2, commencing a kinase signaling cascade that activates the serine-threonine kinase Akt, and (2) the transactivation of the epidermal growth factor receptor (EGFR), leading to a series of protein signals that activate the extracellular signal-regulated kinases (ERK) 1/2. The TRPV1-apoptosis pathway involves Ca2+ influx and efflux between the cytosol, mitochondria, and endoplasmic reticulum (ER), the release of apoptosis-inducing factor (AIF) and cytochrome c from the mitochondria, caspase activation, and DNA fragmentation and condensation. While proliferative mechanisms are typically upregulated in cancerous tissues, shifting the balance to favor apoptosis could support anti-cancer therapies. TRPV1, through [Ca2+]i signaling, influences cancer cell fate; therefore, the modulation of the TRPV1-enforced proliferation–apoptosis balance is a promising avenue in developing anti-cancer therapies and overcoming cancer drug resistance. 
  • 2.0K
  • 09 Nov 2020
Topic Review
Götz Prosthesis Reconstructions
In this entry, the 3D CAD reconstructions and 3D multi-material polymer replica printings of knight Götz von Berlichingen´s first "Iron Hand", which were developed in the last few years at Offenburg University, are presented. Even by today's standards, the first “Iron Hand”–as could be shown in the replicas–demonstrates sophisticated mechanics and well thought-out functionality and still offers inspiration and food for discussion when it comes to the question of an artificial prosthetic replacement for a hand. 
  • 2.0K
  • 14 Jan 2021
Topic Review
Conservation of Crop Genetic Resources
The conservation of crop genetic resources, including their wild relatives, is of utmost importance for the future of mankind. Most crops produce orthodox seeds and can, therefore, be stored in seed genebanks. However, this is not an option for crops and species that produce recalcitrant (non-storable) seeds such as cacao, coffee and avocado, for crops that do not produce seeds at all; therefore, they are inevitably vegetatively propagated such as bananas, or crops that are predominantly clonally propagated as their seeds are not true to type, such as potato, cassava and many fruit trees. Field, in vitro and cryopreserved collections provide an alternative in such cases.
  • 2.0K
  • 11 Sep 2021
Topic Review
Opto-Electronic Oscillators
An opto-electronic oscillator (OEO) is one of the most popular types of oscillators for generating micro- and millimeter wave signals.
  • 2.0K
  • 08 May 2021
Topic Review
Fluorescence Microscopy to Aanalyze Lignin
Lignin is one of the most studied and analyzed materials due to its importance in cell structure and in lignocellulosic biomass. Because lignin exhibits autofluorescence, fluorescence microscopy methods have been developed that allow it to be analyzed and characterized directly in plant tissue and in samples of lignocellulose fibers. Compared to destructive and costly analytical techniques, fluorescence microscopy presents suitable alternatives for the analysis of lignin autofluorescence. The existing qualitative methods are Epifluorescence and Confocal Laser Scanning Microscopy; however, other semi-qualitative methods have been developed that allow fluorescence measurements and to quantify the differences in the structural composition of lignin. The methods are fluorescence lifetime spectroscopy, two-photon microscopy, Föster resonance energy transfer, fluorescence recovery after photobleaching, total internal reflection fluorescence, and stimulated emission depletion. With these methods, it is possible to analyze the transport and polymerization of lignin monomers, distribution of lignin of the syringyl or guaiacyl type in the tissues of various plant species, and changes in the degradation of wood by pulping and biopulping treatments as well as identify the purity of cellulose nanofibers through lignocellulosic biomass.
  • 2.0K
  • 21 Mar 2022
Topic Review
Muslim Heritage in Medicine
Many Greco Arabic Muslim scientists have contributed to the medicine field.
  • 2.0K
  • 17 Aug 2022
Topic Review
Industry 4.0 Concept in Railway Transportation
Industry 4.0 is a concept applied to many different industries and enterprises to make them more intelligent, dynamic, and flexible to meet the challenges of the highly dynamic global market.
  • 2.0K
  • 23 Nov 2023
Topic Review
Extracellular Vesicle
Extracellular vesicles (EVs) are constituted by a group of heterogeneous membrane vesicles secreted by most cell types that play a crucial role in cell–cell communication.
  • 2.0K
  • 25 Mar 2021
Topic Review
Prebiotic Synthesis of Ribose
Prebiotic reactions describe how biomolecules such as ribose, was synthesized and protected from degradation, nucleobases generated from HCN oligomers and other derivatives including prebiotic RNA (preRNA) were formed at the given circumstances. Prebiotic conditions remained a subject of debate, but a reasonable aspect to consider is that tetrahedral structure shaping biomolecules consisted almost exclusively of elements belonging to the CHNOPS group in the periodic table, where capital letters correspond to the elements of carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur. Intermediary steps in the formose reaction network contain aldol condensation, aldose-ketose isomerizations, producing C3 - C6 carbohydrates including pentoses. The generation of genetic material could have developed from the formose reaction to ribose and further to non-genetic prebiotic  RNA (preRNA) [1-9]. Consecutive reactions of this pathway are not known. Those known abiotic chemical reactions were selected that could have resulted in preRNA and genetic RNA (genRNA).  Processes generating primitive life on Earth consisted of three successive stages: i) abiotic reactions generating organic molecules, ii) formation of molecular aggregates showing primitive metabolism, iii) development of primitive cells and organisms resembling those that exist today. Only cellular life is known that adapted in every aspect to conditions that exist only on Earth. Here only the 1st stage, the abiotic phase is dealt with. Prebiotic conditions remained subjects of debate ranging from a strong reductive to a strong oxidative climate. Our theory is based on a mildly reductive atmosphere that could have existed at the beginning of life some 4.3 -4.5 billion years ago, much before the Great Oxidation Event that took place much later 2.3 - 2.5 billion years ago. During the abiotic synthesis of organic molecules, ribose was selected as the precursor to life. .
  • 2.0K
  • 15 Jun 2021
Topic Review
Digital Transformation(DX): Implications for Business
The origin and development of the term “digital transformation” can be examined based on Germany’s Industry 4.0, the Fourth Industrial Revolution, and the development of the digital economy. First, Industry 4.0 was a policy adopted in November 2011 as a strategy for information and communications as a part of Germany’s High-Tech Strategy 2020. Its goal is to achieve innovation in the manufacturing business [6], and according to Deloitte, the goal of this policy encompasses not only the development of specific technology but also a paradigm shift in the manufacturing business.
  • 2.0K
  • 23 Sep 2021
Topic Review
Effects of Extracellular Polymeric Substances on Sludge Properties
Extracellular polymeric substances (EPS) represent the complex high-molecular-weight mixture of polymers excreted by microorganisms generated from cell lysis as well as adsorbed inorganic and organic matter from wastewater. EPS exhibit a three-dimensional, gel-like, highly hydrated matrix that facilitates microbial attachment, embedding, and immobilization. EPS play multiple roles in containments removal, and the main components of EPS crucially influence the properties of microbial aggregates, such as adsorption ability, stability, and formation capacity. Moreover, EPS are important to sludge bioflocculation, settleability, and dewatering properties and could be used as carbon and energy sources in wastewater treatment. 
  • 2.0K
  • 11 Oct 2022
Topic Review
Iodine Deficiency
Iodine deficiency is a global issue and affects around 2 billion people worldwide, with pregnant women as a high-risk group. Iodine-deficiency prevention began in the 20th century and started with global salt iodination programmes, which aimed to improve the iodine intake status globally.
  • 2.0K
  • 19 Feb 2021
Topic Review
Fibroblast Growth Factor-23
Fibroblast growth factor-23 (FGF23) appears to be one of the most promising biomarkers and predictors of cardiovascular risk in patients with heart disease and normal kidney function, but moreover in those with chronic kidney disease (CKD).
  • 2.0K
  • 31 May 2021
Topic Review
Two-Dimensional MoTe2 Hetero-Phase Homojunctions
Two-dimensional (2D) hetero-phase homojunctions comprise a semiconducting phase of a material as the channel and a metallic phase of the material as electrodes. In particular, MoTe2 exhibits intriguing properties and its phase is easily altered from semiconducting 2H to metallic 1T′ and vice versa, owing to the extremely small energy barrier between these two phases. MoTe2 thus finds potential applications in electronics as a representative 2D material with multiple phases. 
  • 2.0K
  • 19 Jan 2022
Topic Review
Soil and Mushrooms
Mushrooms, like other fungi, have a strong impact on soil, both positive and negative. The compost that forms from spent mushroom substrate could be applied to soil as an organic fertilizer, which could increase soil microbial activity and the content of amino acid metabolites in studied orchard. Mushroom also could be used as a bioindicator for soil pollution, such as soil polluted with heavy metals, toxic elements, organic pollutants, radioactives, or isotopes, as well as for health risk indices. The green synthesis of nanoparticles using mushrooms and the potential of bio-nanoremediation for polluted soils. The distinguished roles of mushrooms of soil improvement are considered a crucial dimension for sustainable soil management, which may include controlling soil erosion, improving soil aggregates, increasing soil organic matter content, enhancing the bioavailability of soil nutrients, and resorting to damaged and/or polluted soils. The field of bio-nanoremediation using mushrooms still requires further investigation, particularly regarding the sustainable management of soils.
  • 2.0K
  • 13 Apr 2022
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