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Topic Review
Sustainability Requirements of Residential Buildings
The COVID-19 pandemic is bringing about changes, and alongside these, we can alter the way we design our living spaces. The need for a healthy and comfortable living space is essential to mental, physical well-being, and personal comfort. This entry shows how is COVID-19 Experience Transforming Sustainability Requirements of Residential Buildings.
  • 2.0K
  • 27 Jan 2021
Topic Review
Creatine for Exercise/Sports Performance
Creatine is one of the most studied and popular ergogenic aids for athletes and recreational weightlifters seeking to improve sport and exercise performance, augment exercise training adaptations, and mitigate recovery time. Studies consistently reveal that creatine supplementation exerts positive ergogenic effects on single and multiple bouts of short-duration, high-intensity exercise activities, in addition to potentiating exercise training adaptations.
  • 2.0K
  • 16 Jun 2021
Topic Review
CMS-2 (Programming Language)
CMS-2 is an embedded systems programming language used by the United States Navy. It was an early attempt to develop a standardized high-level computer programming language intended to improve code portability and reusability. CMS-2 was developed primarily for the US Navy’s tactical data systems (NTDS). CMS-2 was developed by RAND Corporation in the early 1970s and stands for "Compiler Monitor System". The name "CMS-2" is followed in literature by a letter designating the type of target system. For example, CMS-2M targets Navy 16-bit processors, such as the AN/AYK-14.
  • 2.0K
  • 07 Nov 2022
Topic Review
Lockheed YO-3
The Lockheed YO-3 "Quiet Star" was an United States single-engined, propeller-driven aircraft that was developed for battlefield observation during the Vietnam War. It was designed to be as quiet as possible, and was intended to observe troop movements in near-silence during the hours of darkness.
  • 2.0K
  • 21 Nov 2022
Topic Review
Pathogenesis of Invasive Listeria monocytogenes Infections
Listeria monocytogenes is a foodborne pathogen that is the causative agent of the human disease, listeriosis. It is primarily a ubiquitous environmental saprophyte found in many environmental niches such as water, soil, and vegetation. Contaminated, often ready-to-eat (RTE) foods are the main transmission vehicles for human L. monocytogenes infections.
  • 2.0K
  • 10 Aug 2022
Topic Review
History of Human-Powered Aircraft
HPAs are aircraft belonging to the class of vehicles known as human-powered vehicles. Early attempts at human-powered flight were unsuccessful because of the difficulty of achieving the high power-to-weight ratio. Prototypes often used ornithopter principles which were not only too heavy to meet this requirement but aerodynamically unsatisfactory. Human-powered aircraft have been successfully flown over considerable distances. However, they are still primarily constructed as engineering challenges rather than for any kind of recreational or utilitarian purpose.
  • 2.0K
  • 31 Oct 2022
Topic Review
Mammalian Na+/H+ Exchanger
The mammalian Na+/H+ exchanger (NHE1, isoform 1) is a ubiquitously expressed membrane protein of mammalian cells. It removes one intracellular proton in exchange for a single extracellular sodium ion. NHE1 has several important physiological functions. It maintains intracellular pH (pHi) while protecting cells from acidification as a result of metabolism. It also regulates cell volume in response to osmotic challenge. There are ten isoforms of NHE that are different gene products. In human pathology, NHE1 is critical in several diseases, including myocardial heart hypertrophy and ischemia reperfusion damage . NHE1 is also important in breast cancer, where it acts as a trigger for metastasis.
  • 2.0K
  • 09 Nov 2020
Topic Review
DNA Damage/Repair Management in Cancers
DNA damage is well recognized as a critical factor in cancer development and progression. DNA lesions create an abnormal nucleotide or nucleotide fragment, causing a break in one or both chains of the DNA strand. When DNA damage occurs, the possibility of generated mutations increases. Genomic instability is one of the most important factors that lead to cancer development. DNA repair pathways perform the essential role of correcting the DNA lesions that occur from DNA damaging agents or carcinogens, thus maintaining genomic stability. Inefficient DNA repair is a critical driving force behind cancer establishment, progression and evolution. A thorough understanding of DNA repair mechanisms in cancer will allow for better therapeutic intervention.
  • 2.0K
  • 27 Oct 2020
Topic Review
Panniculitis in Children
Panniculitides comprise a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. In children, these disorders are rare but can be difficult to diagnose.
  • 2.0K
  • 22 Sep 2021
Topic Review
Timeline of Hepatitis
This is a Timeline of hepatitis, describing major events such as epidemics and medical developments, related to hepatitis A, B, C, D and E.
  • 2.0K
  • 08 Oct 2022
Topic Review
Queensland Lungfish
The Queensland lungfish (Neoceratodus forsteri), also known as the Australian lungfish, Burnett salmon and barramunda, is a surviving member of the family Neoceratodontidae and order Ceratodontiformes. It is one of only six extant lungfish species in the world. Endemic to Australia , the Neoceratodontidae are an ancient family belonging to the class Sarcopterygii, or lobe-finned fishes. Fossil records of this group date back 380 million years, around the time when the higher vertebrate classes were beginning to evolve. Fossils of lungfish almost identical to this species have been uncovered in northern New South Wales, indicating that Neoceratodus has remained virtually unchanged for well over 100 million years, making it a living fossil and one of the oldest living vertebrate genera on the planet. It is one of six extant representatives of the ancient air-breathing Dipnoi (lungfishes) that flourished during the Devonian period (about 413–365 million years ago) and is the outgroup to all other members of this lineage. The five other freshwater lungfish species, four in Africa and one in South America, are very different morphologically from N. forsteri. The Queensland lungfish can live for several days out of the water, if it is kept moist, but will not survive total water depletion, unlike its African counterparts. The small settlement of Ceratodus, Queensland derives its name from that of the Queensland lungfish. The species was named in honour of the squatter and politician William Forster.
  • 2.0K
  • 28 Nov 2022
Topic Review
Sulfur Compounds in Garlic for Asthma Treatment
Asthma is a chronic inflammatory disease in the airways with a multifactorial origin but with inflammation and oxidative stress as related pathogenic mechanisms. Garlic (Allium sativum) is a nutraceutical with different biological properties due to sulfur-containing natural compounds. Studies have shown that several compounds in garlic may have beneficial effects on cardiovascular diseases, including those related to the lungs. Therefore, it is possible to take advantage of the compounds from garlic as nutraceuticals for treating lung diseases.
  • 2.0K
  • 14 Dec 2022
Topic Review
The Tubulin Code in Mitosis
Mitosis relies on the critical contribution of microtubules, as well as several microtubule-associated proteins (MAPs) and motors, to regulate several key mechanisms underlying the faithful segregation of the genetic material during cell division. The mitotic spindle is an anisotropic and highly heterogeneous structure, with dynamic astral microtubules essentially tyrosinated, in contrast with more stable microtubule subpopulations, such as kinetochore and a fraction of interpolar microtubules, which accumulate detyrosinated, Δ2, acetylated and polyglutamylated tubulin.
  • 2.0K
  • 06 Jan 2023
Topic Review
Droid Fonts
Droid is a font family first released in 2007 and created by Ascender Corporation for use by the Open Handset Alliance platform Android and licensed under the Apache License. The fonts are intended for use on the small screens of mobile handsets and were designed by Steve Matteson of Ascender Corporation. The name was derived from the Open Handset Alliance platform named Android.
  • 2.0K
  • 02 Nov 2022
Topic Review
Christian Psychology
Christian psychology is a merger of theology and psychology. It is an aspect of psychology adhering to the religion of Christianity and its teachings of Jesus Christ to explain the human mind and behavior. Christian psychology is a term typically used in reference to Protestant Christian psychotherapists who strive to fully embrace both their religious beliefs and their psychological training in their professional practice. However, a practitioner in Christian psychology would not accept all psychological ideas, especially those that contradicted or defied the existence of God and the scriptures of the Bible. In the United States, American Psychological Association approved courses in Christian psychology are available at undergraduate and graduate levels based on applied science, Christian philosophy and a Christian understanding of psychology. In modern psychological practices, Christianity is incorporated through various therapies. The main choice of practice is Christian counseling. It allows aspects of psychology, such as emotion, to be partially explained by Christian beliefs. The understanding of the human mind is thought of as both psychological and spiritual. G. C. Dilsaver is considered "the father of Christian psychology" according to the Catholic University of America, but the authors of Psychology and the Church: Critical Questions/Crucial Answers suggest that Norman Vincent Peale pioneered the merger of the two fields. Clyde M. Narramore had a major impact on the field of Christian psychology. He was the founding president of the Rosemead School of Psychology, now affiliated with Biola University., and which has published the Journal of Psychology & Theology since 1973. The Russian Journal Konsultativnaya Psikhologiya i Psikhoterapiya publishes a special issue on Christian Psychology every year.
  • 2.0K
  • 01 Dec 2022
Topic Review
Gadolinium-Based Oxide and Oxysulfide Particles
Gadolinium-Based Oxide and Oxysulfide Particles in the biomedical field
  • 2.0K
  • 14 Oct 2021
Topic Review
Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin
Naringin is a nutritional flavanone glycoside that has been shown to be effective in the treatment of a few chronic disorders associated with ageing. Citrus fruits contain a common flavone glycoside that has specific pharmacological and biological properties. Naringin, a flavone glycoside with a range of intriguing characteristics, is abundant in citrus fruits. Naringin has been shown to have a variety of biological, medicinal, and pharmacological effects. Naringin is hydrolyzed into rhamnose and prunin by the naringinase, which also possesses l-rhamnosidase activity. D-glucosidase subsequently catalyzes the hydrolysis of prunin into glucose and naringenin. Naringin is known for having anti-inflammatory, antioxidant, and tumor-fighting effects. Numerous test animals and cell lines have been used to correlate naringin exposure to asthma, hyperlipidemia, diabetes, cancer, hyperthyroidism, and osteoporosis.
  • 2.0K
  • 03 Aug 2023
Topic Review
Food safety and quality analysis at the point of care
Food safety remains a critical issue today. According to the World Health Organization (WHO), approximately two billion people worldwide die from food poisoning caused by bacteria, viruses and parasites annually. These incidences have led to the efforts to develop analytical devices for food safety and quality control. Conventional food safety analytical technologies, including high performance liquid chromatography (HPLC), gas chromatography (GC), quantitative real time polymerase chain reaction (qPCR) and enzyme-linked immunosorbent assay (ELISA), are not only labor intensive and time-consuming, but also high-cost. In addition, most of the diagnostic tests are performed at well-established laboratories. However, resources in central laboratories are limited in developing countries where foodborne diseases are prevalent. Therefore, there seems to be an urgent need to create cost-effective and robust analytical devices for healthcare applications. Recent technological advances have made it possible to develop point-of-care (POC) devices, including chip-based and paper-based devices to rapidly diagnose diseases for providing lifesaving treatment in a timely manner.
  • 2.0K
  • 28 Jan 2022
Topic Review
Daylight Photodynamic Therapy
Daylight photodynamic therapy (dPDT) uses sunlight as a light source to treat superficial skin cancer. Using sunlight as a therapeutic device has been present for centuries, forming the basis of photodynamic therapy in the 20th century. Compared to conventional PDT, dPDT can be a less painful, more convenient and an effective alternative. The first clinical uses of dPDT on skin cancers began in Copenhagen in 2008. Currently, aminolevulinic acid-mediated dPDT has been approved to treat actinic keratosis patients in Europe.
  • 2.0K
  • 13 Dec 2020
Topic Review
Synthetic Biology towards Flavonoid Pharmacokinetics
Flavonoids are a structurally diverse class of natural products that have been found to have a range of beneficial activities in humans. However, the clinical utilisation of these molecules has been limited due to their low solubility, chemical stability, bioavailability and extensive intestinal metabolism in vivo. Recently, the view has been formed that site-specific modification of flavonoids by methylation and/or glycosylation, processes that occur in plants endogenously, can be used to improve and adapt their biophysical and pharmacokinetic properties. The traditional source of flavonoids and their modified forms is from plants and is limited due to the low amounts present in biomass, intrinsic to the nature of secondary metabolite biosynthesis. Access to greater amounts of flavonoids, and understanding of the impact of modifications, requires a rethink in terms of production, more specifically towards the adoption of plant biosynthetic pathways into ex planta synthesis approaches. Advances in synthetic biology and metabolic engineering, aided by protein engineering and machine learning methods, offer attractive and exciting avenues for ex planta flavonoid synthesis.
  • 2.0K
  • 04 Jun 2021
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