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Topic Review
Urban Land Suitability
Urban land suitability could be evaluated from the aspects such as the imbalance of the existing land-use structure and function distribution, along with the scarcity of land resources, so as to provide people with more a rational use of land service space.
  • 2.2K
  • 26 Nov 2021
Topic Review
Piaget SA
Piaget SA (French pronunciation: ​[pja.ʒɛ]) is a Switzerland luxury watchmaker and jeweller. Founded in 1874 by Georges Piaget in the village of La Côte-aux-Fées, Piaget is currently a subsidiary of the Swiss Richemont group. Piaget was founded as a manufacturer of watch movements but began marketing its own line of watches in the 20th century.
  • 2.2K
  • 01 Dec 2022
Topic Review
Full-Reference Image Quality Assessment
To improve data transmission efficiency, image compression is a commonly used method with the disadvantage of accompanying image distortion. There are many image restoration (IR) algorithms, and one of the most advanced algorithms is the generative adversarial network (GAN)-based method with a high correlation to the human visual system (HVS). Having a metric to quantify the image quality to the HVS is always a tough task. Image quality assessment (IQA) can be subjective or objective.
  • 2.2K
  • 09 Jan 2024
Topic Review Peer Reviewed
The Workplace Dynamic of People-Pleasing: Understanding Its Effects on Productivity and Well-Being
This entry explores the psychological, developmental, and organizational dynamics of people-pleasing behavior, analyzing its roots in childhood conditioning, cultural reinforcement, and evolutionary mechanisms. It highlights how chronic approval-seeking compromises authenticity, mental health, and workplace productivity, while proposing interventions for individuals and organizations to cultivate assertiveness and healthier relational patterns.
  • 2.2K
  • 04 Jul 2025
Topic Review
Activism and Social Media
Given their social nature, human beings have a constant need for interacting, cooperating, and communicating with others to work towards the satisfaction of their multiple needs. In this context, activism can be understood as the diversity of behaviors that people exhibit within society and the aim to make problems of social interest visible. Such actions are developed in-person or in digital environments through the internet. These forms of participation are interrelated, and therefore not independent from each other, giving rise to the term “hybrid activism” characterized by the development of integrated actions in both online and offline platforms.
  • 2.2K
  • 25 Sep 2021
Topic Review
Data Acquisition and Storage for Smart Manufacturing
The evolution of technology and especially the Internet of Things (IoT) has led to a new kind of manufacturing known as Smart Manufacturing. Smart Manufacturing is an application of the IoT that focuses on using inexpensive, small-sized, and smart devices that are all interconnected so that they can increase productivity and improve the health of the machines. Big Data in Smart Manufacturing systems are continuously generated data in high volumes produced by said smart devices and are available in various forms, e.g., log files, signal streams, or sensor data. A Big Data analysis system should be able to use these data in real time, as well as save them for historical analysis and long-term pattern detection.
  • 2.2K
  • 10 Mar 2022
Topic Review
Tools in Measurement of Treatment in Lipoedema
Due to insufficient knowledge of lipoedema, the treatment of Lipoedema is undoubtedly challenging. However, more and more researchers attempt to incorporate the most effective lipoedema treatment methods. When assessing a new therapeutic method, choosing correct, objective tools to measure the therapeutic outcome is very important. The tools used in evaluating the effectiveness of conservative treatment in women with lipoedema are: volume and circumference measurement, waist-to-hip ratio, body fat percentage, ultrasonography, VAS scale, quality of life scales (SF-36, RAND-36), symptom severity questionnaire (QuASiL), Lower Extremity Functional Scale and 6 min walk.
  • 2.2K
  • 20 Jun 2022
Topic Review
Sage
A sage (Ancient Greek:, sophos), in classical philosophy, is someone who has attained wisdom. The term has also been used interchangeably with a 'good person' (Ancient Greek:, agathos), and a 'virtuous person' (Ancient Greek:, spoudaios). Among the earliest accounts of the sage begin with Empedocles' Sphairos. Horace describes the Sphairos as "Completely within itself, well-rounded and spherical, so that nothing extraneous can adhere to it, because of its smooth and polished surface." Alternatively, the sage is one who lives "according to an ideal which transcends the everyday." Several of the schools of Hellenistic philosophy have the sage as a featured figure. Karl Ludwig Michelet wrote that "Greek religion culminated with its true god, the sage"; Pierre Hadot develops this idea, stating that "the moment philosophers achieve a rational conception of God based on the model of the sage, Greece surpasses its mythical representation of its gods." Indeed, the actions of the sage are propounded to be how a god would act in the same situation.
  • 2.2K
  • 05 Nov 2022
Topic Review
PARP Inhibitor-Induced Synthetic Lethality
The advanced development of synthetic lethality has opened the doors for specific anti-cancer medications of personalized medicine and efficient therapies against cancers. One of the most popular approaches being investigated is targeting DNA repair pathways as the implementation of the poly-ADP ribose polymerase 1 (PARP) inhibitor (PARPi) into individual or combinational therapeutic schemes. Such treatment has been effectively employed against homologous recombination-defective solid tumors as well as hematopoietic malignancies. In the most common aspect of precision medicine, PARPi triggers synthetic lethality in cancer cells harboring BRCA1/2 mutations/deficiencies. 
  • 2.2K
  • 05 Dec 2022
Topic Review
Hypoxia-Inducible Factor in the Development of Pulmonary Hypertension
Pulmonary hypertension (PH) is a severe progressive lung disorder characterized by pulmonary vasoconstriction and vascular remodeling, culminating in right-sided heart failure and increased mortality.
  • 2.2K
  • 19 Sep 2022
Topic Review
Aries
Aries, recognized by the International Astronomical Union (IAU), is a constellation in the northern celestial hemisphere. Representing the ram from ancient Greek mythology, Aries is one of the twelve zodiac constellations and holds significance in astrology and astronomy alike. Its celestial prominence and position along the ecliptic make it a notable feature in the night sky, marking the vernal equinox and heralding the beginning of spring in the northern hemisphere.
  • 2.2K
  • 29 Feb 2024
Topic Review
Foot-and-Mouth Disease Virus
Foot-and-mouth disease (FMD) is an acute and highly contagious disease affecting the cloven-hoofed animals, such as pigs and cattle. The pathogen that causes FMD is known as FMD virus (FMDV), a single-stranded positive-sense RNA virus that is classified into the genus Aphthovirus in the family Picornaviridae.
  • 2.2K
  • 15 Sep 2020
Topic Review
MDPI English Writing Prize 2020
The MDPI Writing Prize is an annual award supported by MDPI Author Services, which provides services including language editing, reformatting, plagiarism checks. The winners of the 2020 MDPI Writing Prize about the theme “My work and the United Nations Sustainable Development Goals” are posted on Encyclopedia. In this competition, we received many excellent submissions from entrants who shared their inspirational and thought-provoking work.
  • 2.2K
  • 01 Mar 2021
Topic Review
High-Density Lipoprotein
High-density lipoprotein (HDL), the smallest and most dense lipoprotein, is composed of a central hydrophobic non-polar lipid core, consisting of primarily triacylglycerols and cholesterol esters.
  • 2.2K
  • 29 Jan 2022
Topic Review
Groundwater Remediation Technologies
Groundwater contamination is one of the most concerning issues from uranium mining activities. Radionuclides cannot be destroyed or degraded, unlike some organic contaminants (and similar to metals). Besides, sites, where radionuclides may be found, are mainly radioactive and mixed waste disposal areas, and therefore many other contaminants may also be present in groundwater.
  • 2.2K
  • 05 Jul 2021
Topic Review
Thermosensitive Gelling Rectal Systems
Thermosensitive gelling system is drug delivery system that becomes a gel at physiological temperature.  The transition sol-gel temperature (Tsol-gel) is below body temperature (<37◦C), making it possible to prepare liquid preparations, which gel back at body temperature. Thermosensitive gelling system could be used to rectal administration. Rectal drug delivery is an effective alternative to oral and parenteral treatments. This route allows for both local and systemic drug therapy. Traditional rectal dosage formulations have historically been used for localised treatments, including laxatives, hemorrhoid therapy and antipyretics. However, this form of drug dosage often feels alien and uncomfortable to a patient, encouraging refusal. Thermosensitive liquid suppositories are easier to administer to the anus as they remain liquid at lower temperatures. In addition, this rectal gel minimize the feeling of a foreign body compared with solid suppositories, does not cause any harm on mucosal layers and act as mucoadhesive to the rectal tissues preventing leakage after administration.
  • 2.2K
  • 29 Jul 2021
Topic Review
Argument Technology
Argument technology is a sub-field of artificial intelligence that focuses on applying computational techniques to the creation, identification, analysis, navigation, evaluation and visualisation of arguments and debates. In the 1980s and 1990s, philosophical theories of arguments in general, and argumentation theory in particular, were leveraged to handle key computational challenges, such as modeling non-monotonic and defeasible reasoning and designing robust coordination protocols for multi-agent systems. At the same time, mechanisms for computing semantics of Argumentation frameworks were introduced as a way of providing a calculus of opposition for computing what it is reasonable to believe in the context of conflicting arguments. With these foundations in place, the area was kick-started by a workshop held in the Scottish Highlands in 2000, the result of which was a book coauthored by philosophers of argument, rhetoricians, legal scholars and AI researchers. Since then, the area has been supported by various dedicated events such as the International Workshop on Computational Models of Natural Argument (CMNA) which has run annually since 2001; the International Workshop on Argument in Multi Agent Systems (ArgMAS) annually since 2004; the Workshop on Argument Mining, annually since 2014, and the Conference on Computational Models of Argument (COMMA), biennially since 2006. Since 2010, the field has also had its own journal, Argument & Computation, which was published by Taylor & Francis until 2016 and since then by IOS Press. One of the challenges that argument technology faced was a lack of standardisation in the representation and underlying conception of argument in machine readable terms. Many different software tools for manual argument analysis, in particular, developed idiosyncratic and ad hoc ways of representing arguments which reflected differing underlying ways of conceiving of argumentative structure. This lack of standardisation also meant that there was no interchange between tools or between research projects, and little re-use of data resources that were often expensive to create. To tackle this problem, the Argument Interchange Format set out to establish a common standard that captured the minimal common features of argumentation which could then be extended in different settings. Since about 2018, argument technology has been growing rapidly, with, for example, IBM's Grand Challenge, Project Debater, results for which were published in Nature in March 2021; German research funder, DFG's nationwide research programme on Robust Argumentation Machines, RATIO, begun in 2019; and UK nationwide deployment of The Evidence Toolkit by the BBC in 2019. A 2021 video narrated by Stephen Fry provides a summary of the societal motivations for work in argument technology. Argument technology has applications in a variety of domains, including education, healthcare, policy making, political science, intelligence analysis and risk management and has a variety of sub-fields, methodologies and technologies.
  • 2.2K
  • 08 Oct 2022
Topic Review
Peroxyacetic Acid Pretreatment in Lignocellulose Biorefinery
The stubborn and complex structure of lignocellulose hinders the valorization of each component of cellulose, hemicellulose, and lignin in the biorefinery industries. Therefore, efficient pretreatment is an essential and prerequisite step for lignocellulose biorefinery. A considerable number of studies have focused on peroxyacetic acid (PAA) pretreatment in lignocellulose fractionation and some breakthroughs have been achieved in recent decades. 
  • 2.2K
  • 12 Oct 2022
Topic Review
Hooker with a Heart of Gold
The hooker with a heart of gold (also the whore with a heart of gold or the tart with a heart) is a stock character involving a courtesan or prostitute with a hidden integrity and kindness. The character, traditionally female, is usually an example of irony: an allegedly immoral woman who demonstrates virtues absent in woman morally correct for the role.
  • 2.2K
  • 20 Oct 2022
Topic Review
Hypoactive Sexual Desire Disorder
Hypoactive sexual desire disorder (HSDD), hyposexuality or inhibited sexual desire (ISD) is considered a sexual dysfunction in some jurisdictions and is characterized as a lack or absence of sexual fantasies and desire for sexual activity, as judged by a clinician. For this to be regarded as a disorder, it must cause marked distress or interpersonal difficulties and not be better accounted for by another mental disorder, a drug (legal or illegal), or some other medical condition. A person with ISD will not start, or respond to their partner's desire for, sexual activity. HSDD affects approximately 10% of all pre-menopausal women in the United States, or about 6 million women. There are various subtypes. HSDD can be general (general lack of sexual desire) or situational (still has sexual desire, but lacks sexual desire for current partner), and it can be acquired (HSDD started after a period of normal sexual functioning) or lifelong (the person has always had no/low sexual desire.) In the DSM-5, HSDD was split into male hypoactive sexual desire disorder and female sexual interest/arousal disorder. It was first included in the DSM-III under the name inhibited sexual desire disorder, but the name was changed in the DSM-III-R. Other terms used to describe the phenomenon include sexual aversion and sexual apathy. More informal or colloquial terms are frigidity and frigidness.
  • 2.2K
  • 31 Oct 2022
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