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Topic Review
Camelopardalis
Camelopardalis, recognized by the International Astronomical Union (IAU), is a constellation located in the northern celestial hemisphere. Its name is derived from the Latin word for "giraffe," reflecting its association with this graceful and majestic creature.
  • 2.2K
  • 29 Feb 2024
Topic Review
Properties of Claudin-2
Claudin-2 is a member of the claudin family of epithelial tight junction proteins expressed mostly in the kidneys and gastrointestinal tract. Its role as a cation-selective and water permeable paracellular channel is well studied. In addition, newly emerging strong evidence also shows that it can modulate proliferation, migration, and cell fate determination. These effects appear to be due to its interactions with cytosolic adapters, that connect it to key signaling pathways. A multitude of new data document dysregulated claudin-2 expression in many pathologies including cancer, inflammation, and fibrosis. Thus, changes in claudin-2 expression may contribute to the generation, maintenance, and/or progression of diseases through both permeability-dependent and -independent mechanisms. Based on this, efforts are underway to develop therapies targeting claudin-2 with the hope of benefiting patients with a variety of disease. 
  • 2.2K
  • 30 Oct 2020
Topic Review
Gamified Waste Management Tool
Waste management is an increasingly visible and essential element to functioning civilization. However, while the theory of waste management is studied widely, waste management remains for many a difficult concept to understand. There is an opportunity to create an informative, easy-to-use simulator to help all types of individuals build an understanding of waste management and to evaluate the impact of various changes on waste management performance, particularly in the context of gamified tools. 
  • 2.2K
  • 17 Feb 2022
Topic Review
Ophthalmoscopy
Ophthalmoscopy, also called funduscopy, is a test that allows a health professional to see inside the fundus of the eye and other structures using an ophthalmoscope (or funduscope). It is done as part of an eye examination and may be done as part of a routine physical examination. It is crucial in determining the health of the retina, optic disc, and vitreous humor. The pupil is a hole through which the eye's interior will be viewed. Opening the pupil wider (dilating it) is a simple and effective way to better see the structures behind it. Therefore, dilation of the pupil (mydriasis) is often accomplished with medicated eye drops before funduscopy. However, although dilated fundus examination is ideal, undilated examination is more convenient and is also helpful (albeit not as comprehensive), and it is the most common type in primary care. An alternative or complement to ophthalmoscopy is to perform a fundus photography, where the image can be analysed later by a professional.
  • 2.2K
  • 19 Oct 2022
Topic Review
Project 4.1
Project 4.1 was the designation for a medical study conducted by the United States of those residents of the Marshall Islands exposed to radioactive fallout from the March 1, 1954 Castle Bravo nuclear test at Bikini Atoll, which had an unexpectedly large yield. Government and mainstream historical sources point to the study being organized on March 6 or March 7, 1954, six days after the Bravo shot.
  • 2.2K
  • 07 Nov 2022
Topic Review
Reflection (Computer Programming)
In computer science, reflection is the ability of a process to examine, introspect, and modify its own structure and behavior.
  • 2.2K
  • 11 Oct 2022
Topic Review
Triploid Fish
Over the past decades, evidence is emerging that triploid fish exhibit interesting genetic, anatomical, cellular and biochemical peculiarities with potential growth advantages for the Aquaculture industry are including economic gains and improved feed conversion rate. A review of the current literature indicates that an assessment of the possible advantages and disadvantages of farming triploid sea bass should include the effects of ploidy on flesh quality parameters and in the capacity for aerobic and anaerobic metabolism at different seasonal temperatures. 
  • 2.2K
  • 05 Nov 2020
Topic Review
ADP-Ribosyltransferase Toxin
ADP-ribosyltransferases (ARTs) are a well-known type of bacterial toxin. They transfer an ADP-ribose moiety from nicotinamide adenine dinucleotide (NAD+) onto a target protein to generate an ADP-ribosylated protein and nicotinamide. The bulky and negatively charged ADP-ribose moiety affects the protein function by sterically blocking interactions with partner molecules, inducing conformational changes, or creating docking sites for new interaction partners.
  • 2.2K
  • 25 Jan 2021
Topic Review
Agate
Agate ‒ a spectacular form of SiO2 and a famous gemstone ‒ is commonly characterized as banded chalcedony. In detail, chalcedony layers in agates can be intergrown or intercalated with macro-crystalline quartz, quartzine, opal-C, opal-CT, cristobalite and/or moganite. In addition, agates often contain considerable amounts of mineral inclusions and water as both interstitial molecular H2O and silanol groups.
  • 2.2K
  • 16 Apr 2021
Topic Review
Impact of Rutin on Buckwheat Grain Metabolites
Tartary buckwheat (Fagopyrum tataricum Gaertn.) is grown in eastern and central Asia (the Himalayan regions of China, Nepal, Bhutan and India) and in central and eastern Europe (Luxemburg, Germany, Slovenia and Bosnia and Herzegovina). It is known for its high concentration of rutin and other phenolic metabolites. Besides the grain, the other aboveground parts of Tartary buckwheat contain rutin as well. After the mixing of the milled buckwheat products with water, the flavonoid quercetin is obtained in the flour–water mixture, a result of rutin degradation by rutinosidase. Heating by hot water or steam inactivates the rutin-degrading enzymes in buckwheat flour and dough. The low buckwheat protein digestibility is due to the high content of phenolic substances. Phenolic compounds have low absorption after food intake, so, after ingestion, they remain for some time in the gastrointestinal tract. They can act in an inhibitory manner on enzymes, degrading proteins and other food constituents. In common and Tartary buckwheat, the rutin and quercetin complexation with protein and starch molecules has an impact on the in vitro digestibility and the appearance of resistant starch and slowly digestible proteins. Slowly digestible starch and proteins are important for the functional and health-promoting properties of buckwheat products. 
  • 2.2K
  • 19 Apr 2022
Topic Review
West Timorese Farmers in Land Management
Facing the marginal land conditions of West Timor, adaptation efforts by farmers related to food production and planting activities have led to various local knowledge and practices, including the existence of agricultural commodities that are derived from natural selection, which have been ongoing for quite some time. 
  • 2.2K
  • 02 Jun 2022
Topic Review
Crustacean Waste-Derived Chitosan
Chitosan is obtained from chitin that in turn is recovered from marine crustacean wastes. The recovery methods and their varying types and the advantages of the recovery methods are briefly discussed. Chitin is the major component of cuticles of insects (cockroach, beetle, true fly, and worm), fungal cell walls (Aspergillus niger, Mucor rouxii, Penicillum notatum, yeast) and green algae. The recovery methods and their varying types and the advantages of the recovery methods are briefly discussed. 
  • 2.2K
  • 09 Jun 2022
Topic Review
Indonesian Car
Indonesian national car is the categorization of a Low Cost Green Car (LCGC) in Indonesia with the following initial specifications: Priced between 50,000,000 Indonesian rupiah for villagers to Rp 85,000,000 for the general public[1]; Fuel efficiency of at least 20 km/l (56 mpg‑imp; 47 mpg‑US); Made up from at least 60% domestic components.
  • 2.2K
  • 16 Nov 2022
Topic Review
Soil Constraints in an Arid Environment
Arid environments are characterized by a higher evaporation than precipitation, as well as persistent water shortages, frequent droughts, high climate variability, and high wind velocity. These soil constraints can be ameliorated and the crop yields increased through case-specific optimization of irrigation and drainage management, enhancing the native beneficial soil microbes, and combinations of soil amendments, conditioners, and residue management.
  • 2.2K
  • 18 Jan 2023
Topic Review
Cymbidium Orchids
Cymbidium is an economically important genus in the orchid family (Orchidaceae) that has a pronounced medicinal and ornamental value. Medicinally, the plant is employed as a tonic to treat weakness in chronic diseases, dizziness, eye problems, burns, and wounds, etc. Cymbidiums are highly prized for their graceful flowers and sweet fragrance and are among the top ten most popular cut flowers. They are one of the most important commercial orchid groups and account for 3% of cut flowers in floriculture. Some orchid species in this genus are particularly threatened by excessive harvesting, so conservation measures are needed.
  • 2.2K
  • 26 Jun 2023
Topic Review
Enzymatic Activity
Enzymatic Activity is a sensitive indicator of changes in soil environment, and it changes depending on the farming system. 
  • 2.2K
  • 30 Oct 2020
Topic Review
Endocannabinoid System (ECS)
The endocannabinoid system (ECS) is an essential signaling system in mammal physiology regulating several biological and disease conditions. ECS’s three main components are (i) cannabinoids receptors (CBR) CBR-1 and CBR-2; (ii) signaling molecules that are lipid-based termed the “endocannabinoids” (EC), endogenous ligands of the CBRs; and (iii) enzymes responsible for synthesizing and degrading ECs. ECS regulates multiple physiological processes, such as brain plasticity and neuronal development, cell death, inflammation, sleep, appetite, pain, and anxiety.
  • 2.2K
  • 24 Mar 2022
Topic Review
Bilingualism, Culture, and Executive Functions
Much research to date exploring whether bilinguals have an advantage over monolinguals in terms of executive functions (EF) often conflates bilingualism with bi/multiculturalism. Here, the researchers review the evidence for why culture should be carefully scrutinised as a critical variable that could mediate bilinguals' EF.
  • 2.2K
  • 30 Nov 2022
Topic Review
Red Wood Ants
The consequences of anthropogenic climate change are one of the major concerns of conservation biology. A cascade of negative effects is expected to affect various ecosystems, one of which is Central European coniferous forests and their unique biota. These coniferous forests are the primary habitat of many forest specialist species such as red wood ants. Climate change-induced rising of temperature allows trees to skip winter hibernation, making them more vulnerable to storms that cause wind felling, and in turn, promotes bark beetle infestations that results in unscheduled clear-cuttings. Red wood ants can also be exposed to such habitat changes. We investigated the effects of bark beetle-induced clear-cutting and the absence of coniferous trees on colonies of Formica polyctena, including a mixed-coniferous forest as a reference. Our aim was to investigate how these habitat features affect the nest characteristics and nesting habits of F. polyctena. Our results indicate that, in the absence of conifers, F. polyctena tend to use different alternatives for nest material, colony structure, and food sources. However, the vitality of F. polyctena colonies significantly decreased (smaller nest mound volumes). Our study highlights the ecological flexibility of this forest specialist and its potential to survive under extreme conditions.
  • 2.2K
  • 30 Sep 2020
Topic Review
β-butyrolactone
Over 35 years ago, researchers originally reported on the anionic ring-opening polymerization (ROP) of β-butyrolactone (BBL) into poly(β-butyrolactone) (poly(BBL)), which is an amorphous, atactic analogue of isotactic poly([R]-β-hydroxybutyrate) (PHB), a promising and widely used natural biodegradable polyester. 
  • 2.2K
  • 30 Dec 2021
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