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Topic Review
Small Molecules for Corneal Neovascularization
Multiple natural-source and synthetic small molecules have been tested preclinical for treating corneal neovascularization. Such small molecules include synthetic inhibitors of the vascular endothelial growth factor (VEGF) receptor and other tyrosine kinases, plus repurposed antimicrobials, as well as natural source-derived flavonoid and non-flavonoid phytochemicals, immunosuppressants, vitamins, and histone deacetylase inhibitors.
  • 2.2K
  • 17 Aug 2020
Topic Review
Ultrasound of Small Bowel Obstruction
Ultrasound is an excellent initial imaging modality for assisting physicians in the rapid and accurate diagnosis of small bowel occlusion.
  • 2.2K
  • 22 Apr 2021
Topic Review
Photocatalysis for Air Purification
Photocatalysis since a long time has been recognized  as a eco-technology to fight air pollution. It is focused  on the generation of reactive oxygen species (ROSs) under light on the surface of a photocatalytic material. It could be applied in different manners such as for the purification of industrial polluted air, photoconversion of toxic gas into valuable products, self-cleaning systems, photocatalytic filters, etc. However, it faces some technological issues limiting its wide application in real-world.  
  • 2.2K
  • 17 May 2021
Topic Review
Ambidextrous Organization
Organizational ambidexterity refers to an organization's ability to be efficient in its management of today's business and also adaptable for coping with tomorrow's changing demand. Just as being ambidextrous means being able to use both the left and right hand equally, organizational ambidexterity requires the organizations to use both exploration and exploitation techniques to be successful.
  • 2.2K
  • 07 Nov 2022
Topic Review
Humus
Etymologically the word "humus" means ground, dirt; the meaning of "homo" or "human" is near to earthling or being of the earth, earth here referring to the ground, or dirt (https://sites.psu.edu/josephvadella/2017/09/08/origins-of-human/). Essentially the words humus and human mean "connected to the earth", earth understood as dust, soil, dirt. The best way to express such a concept comes from an ancient religious Latin sentence: "pulvis est et pulvis reverteris", solemnly pronounced by priests as they deposited a pinch of ash on the believers' heads. Consider that earth has also become the name of the whole planet Earth, and that the Lovelock's Gaia hypothesis assigns the planet the functioning of a quasi-organism (https://en.wikipedia.org/wiki/Gaia_hypothesis). The notion of humus contains and makes explicit the very concept of all existing matter. What is matter (living or not), if always, at a given cyclical moment, matter is forced to disappear by a principle which founds the future of this same matter? Understanding even partially this principle is useful for every single individual and for the whole of the co-evolving society.
  • 2.2K
  • 01 Aug 2022
Topic Review
Non-Viral Vectors in Gene Therapy
Efficient delivery of genetic material into cells is a critical process to translate gene therapy into clinical practice. In this sense, the increased knowledge acquired during past years in the molecular biology and nanotechnology fields has contributed to the development of different kinds of non-viral vector systems as a promising alternative to virus-based gene delivery counterparts. 
  • 2.2K
  • 28 Jul 2021
Topic Review
Corvids in Urban Environments
With regard to their high adaptability to human settlements and global distribution, corvid birds (crows, ravens, jays, etc.) are good models to understand the impacts of urbanization on wildlife. At least 30 corvid species have become successfully accustomed or adapted to urbanized environments. The availability of easily accessible food and artificial nesting sites, coupled with low levels of predation, were found as the most important factors benefitting corvids in cities around the world. 
  • 2.2K
  • 13 Dec 2021
Topic Review
Northern Sea Cucumber
Sea cucumber (Cucumaria frondosa) is the most abundant and widely distributed species in the cold waters of North Atlantic Ocean. C. frondosa contains a wide range of bioactive compounds, mainly collagen, cerebrosides, glycosaminoglycan, chondroitin sulfate, saponins, phenols, and mucopolysaccharides, which demonstrate unique biological and pharmacological properties. In particular, the body wall of this marine invertebrate is the major edible part and contains most of the active constituents, mainly polysaccharides and collagen, which exhibit numerous biological activities, including anticancer, anti-hypertensive, anti-angiogenic, anti-inflammatory, antidiabetic, anti-coagulation, antimicrobial, antioxidation, and anti- osteoclastogenic properties.
  • 2.2K
  • 17 Jan 2022
Topic Review
A Thousand Miles
"A Thousand Miles" (originally titled "Interlude") is the debut single written and recorded by American pop singer Vanessa Carlton. Produced by Curtis Schweitzer and Ron Fair, the song was released as the lead single for Carlton's album Be Not Nobody (2002). Her signature song, it became Carlton's breakthrough hit and one of the most popular songs of the year. To date, it remains Carlton's biggest hit in the United States, and her only single to reach the top ten of the Billboard Hot 100. The song had widespread success worldwide, reaching number one in Australia, where it was most successful, the top five in Ireland, and the top ten in the United Kingdom, France, Italy, and the Netherlands. The song has been covered by numerous artists, including Icarus the Owl, Victoria Justice, David Archuleta, and the Glee Cast. It has also been sampled by T.I., Cheryl Cole, and Cam’ron. It has also become a popular internet meme.
  • 2.2K
  • 20 Oct 2022
Topic Review
Volcanology of Venus
The surface of Venus is dominated by volcanic features and has more volcanoes than any other planet in the Solar System. It has a surface that is 90% basalt, and about 65% of the planet consists of a mosaic of volcanic lava plains, indicating that volcanism played a major role in shaping its surface. There are more than 1,000 volcanic structures and possible periodic resurfacing of Venus by floods of lava. The planet may have had a major global resurfacing event about 500 million years ago, from what scientists can tell from the density of impact craters on the surface. Venus has an atmosphere rich in carbon dioxide, with a density that is 90 times greater than Earth's atmosphere. Even though there are over 1,600 major volcanoes on Venus, none are known to be erupting at present and most are probably long extinct. However, radar sounding by the Magellan probe revealed evidence for comparatively recent volcanic activity at Venus's highest volcano Maat Mons, in the form of ash flows near the summit and on the northern flank. Although many lines of evidence suggest that Venus is likely to be volcanically active, present-day eruptions at Maat Mons have not been confirmed. Nevertheless, other more recent studies, in January 2020, suggests Venus is currently volcanically active.
  • 2.2K
  • 22 Nov 2022
Topic Review
Behavioral Neuroscience
Behavioral neuroscience, also known as biological psychology, biopsychology, or psychobiology, is the application of the principles of biology to the study of physiological, genetic, and developmental mechanisms of behavior in humans and other animals.
  • 2.2K
  • 23 Nov 2022
Topic Review
Environmental Data Visualization Tools
The visualization of environmental data is important for the assessment of processes taking place in the environment. Visualization of collected data includes plotting charts or drawing maps with values of the variables collected by monitoring system or predicted by modelling software. There are many tools used by environmental scientists developed for the purpose of data visualization.
  • 2.2K
  • 15 Jul 2022
Topic Review
Room Temperature Sodium Sulfur Batteries
Lithium metal batteries have achieved large-scale application, but still have limitations such as poor safety performance and high cost, and limited lithium resources limit the production of lithium batteries. The construction of these devices is also hampered by limited lithium supplies. Therefore, it is particularly important to find alternative metals for lithium replacement. Sodium has the properties of rich in content, low cost and ability to provide high voltage, which makes it an ideal substitute for lithium. Sulfur-based materials have attributes of high energy density, high theoretical specific capacity and are easily oxidized. They may be used as cathodes matched with sodium anodes to form a sodium-sulfur battery. Traditional sodium-sulfur batteries are used at a temperature of about 300 °C. In order to solve problems associated with flammability, explosiveness and energy loss caused by high-temperature use conditions, most research is now focused on the development of room temperature sodium-sulfur batteries. Regardless of safety performance or energy storage performance, room temperature sodium-sulfur batteries have great potential as next-generation secondary batteries. This article summarizes the working principle and existing problems for room temperature sodium-sulfur battery, and summarizes the methods necessary to solve key scientific problems to improve the comprehensive energy storage performance of sodium-sulfur battery from four aspects: cathode, anode, electrolyte and separator.
  • 2.2K
  • 06 Apr 2021
Topic Review Video
Blockchain Acceptance Models
Blockchain is a promising breakthrough technology that is highly applicable in manifold sectors. The adoption of blockchain technology is accompanied by a range of issues and challenges that make its implementation complicated. To facilitate the successful implementation of blockchain technology, several blockchain adoption frameworks have been developed. However, selecting the appropriate framework based on the conformity of its features with the business sector may be challenging for decision-makers. 
  • 2.2K
  • 18 Feb 2022
Topic Review
National Herald Scam
The National Herald scam is an ongoing case in a Delhi court filed by Indian economist and politician Subramanian Swamy against politicians Sonia Gandhi and Rahul Gandhi, their companies and associated persons. As per the complaint filed in the court of the Metropolitan Magistrate, Associated Journals Limited (AJL) took an interest-free loan of ₹90.25 crore (US$13 million) from Indian National Congress. It is alleged that the loan was not repaid. A closely held company, Young Indian, was incorporated in November 2010 with a capital of ₹50 lakh (US$70,000) and it acquired almost all the shareholding of AJL and all its properties (alleged to be worth ₹5,000 crore (US$700 million)). Swamy alleged criminal misappropriation by both Sonia Gandhi and Rahul Gandhi. The courts have determined that a prima face case has been established in the matter.
  • 2.2K
  • 19 Oct 2022
Topic Review
Obesity as A Cause of Cancer
Obesity is defined as the accumulation of an excessive amount of body fat. The correlation of obesity with increased cancer incidence and death has been well established. 
  • 2.2K
  • 03 Nov 2022
Topic Review
High-Performance Liquid Chromatography Analysis of Coffee-Based Products
Coffee is a very popular beverage worldwide. However, its composition and characteristics are affected by a number of factors, such as geographical and botanical origin, harvesting and roasting conditions, and brewing method used. As coffee consumption rises, the demands on its high quality and authenticity naturally grows as well. Unfortunately, at the same time, various tricks of coffee adulteration occur more frequently, with the intention of quick economic profit. Many analytical methods have already been developed to verify the coffee authenticity, in which the high-performance liquid chromatography (HPLC) plays a crucial role, especially thanks to its high selectivity and sensitivity. 
  • 2.2K
  • 14 Nov 2022
Topic Review
Innovative and Competitive in Tourism Destinations
New tourism destinations and product supply are increasingly popular strategies among industry players to create competitiveness and sustaining the tourism industry. The tourism industry has become more vibrant since globalization emerged with technological changes, thus influencing human travel movements, life-styles, and current trends. 
  • 2.2K
  • 06 Feb 2023
Topic Review
Limb Development
The function of retinoic acid (RA) during limb development is still debated, as loss and gain of function studies led to opposite conclusions. With regard to limb initiation, genetic studies demonstrated that activation of FGF10 signaling is required for the emergence of limb buds from the trunk, with Tbx5 and RA signaling acting upstream in the forelimb field, whereas Tbx4 and Pitx1 act upstream in the hindlimb field. Early studies in chick embryos suggested that RA as well as Meis1 and Meis2 (Meis1/2) are required for subsequent proximodistal patterning of both forelimbs and hindlimbs, with RA diffusing from the trunk, functioning to activate Meis1/2 specifically in the proximal limb bud mesoderm. However, genetic loss of RA signaling does not result in loss of limb Meis1/2 expression and limb patterning is normal, although Meis1/2 expression is reduced in trunk somitic mesoderm. More recent studies demonstrated that global genetic loss of Meis1/2 results in a somite defect and failure of limb bud initiation. Other new studies reported that conditional genetic loss of Meis1/2 in the limb results in proximodistal patterning defects, and distal FGF8 signaling represses Meis1/2 to constrain its expression to the proximal limb.
  • 2.2K
  • 19 Jan 2021
Topic Review
Deep Learning in SOC Estimation for Li-Ion Batteries
As one of the critical state parameters of the battery management system, the state of charge (SOC) of lithium batteries can provide an essential reference for battery safety management, charge/discharge control, and the energy management of electric vehicles (EVs). The SOC estimation of a Li-ion battery in the deep learning method uses deep learning theory of computer science to build a model that builds the approximate relationship between input data (voltage, current, temperature, power, capacity, etc.) and output data (SOC) by available data. According to different neural network structures, it can be classified as a single, hybrid, or trans structure. 
  • 2.2K
  • 02 Nov 2022
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