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Topic Review
Lightweight Aggregate Concrete
Lightweight aggregate concrete (LWAC) exhibits the advantages of thermal insulation, reduces energy consumption building costs, improves building efficiency and easy construction. Furthermore, the utilization of industrial wastes in concrete is advantageous in terms of environmental sustainability.
  • 2.3K
  • 28 Mar 2022
Topic Review
Numerically Controlled Oscillator
A numerically controlled oscillator (NCO) is a digital signal generator which creates a synchronous (i.e. clocked), discrete-time, discrete-valued representation of a waveform, usually sinusoidal. NCOs are often used in conjunction with a digital-to-analog converter (DAC) at the output to create a direct digital synthesizer (DDS). Numerically controlled oscillators offer several advantages over other types of oscillators in terms of agility, accuracy, stability and reliability. NCOs are used in many communications systems including digital up/down converters used in 3G wireless and software radio systems, digital PLLs, radar systems, drivers for optical or acoustic transmissions, and multilevel FSK/PSK modulators/demodulators.
  • 2.3K
  • 11 Oct 2022
Topic Review
Chalicotherium
Chalicotherium (Ancient Greek χαλιξ/khalix, khalik-: pebble/gravel + θηρίον/thērion, diminutive of θηρ/thēr : beast) is a genus of extinct odd-toed ungulates of the order Perissodactyla and family Chalicotheriidae, found in Europe, Africa, Asia, and North America from the Late Oligocene to Early Pliocene, 28.4–3.6 million years ago, existing for approximately 24.8 million years. This animal would look much like other chalicotheriid species: an odd-looking herbivore with long clawed forelimbs and stouter weight-bearing hindlimbs. The type species, Chalicotherium goldfussi, from Miocene and Pliocene Europe, was described by Johann Jakob Kaup in 1833.
  • 2.3K
  • 22 Nov 2022
Topic Review
Eyelash Extensions
Eyelash extensions are used to enhance the length, curliness, fullness, and thickness of natural eyelashes. The extensions may be made from several materials including mink, synthetic, or horse hair. The main method of applying the extensions is by using an adhesive glue to individually stick the extensions to the eyelash line. False eyelashes and eyelash extensions are not the same.
  • 2.3K
  • 28 Nov 2022
Topic Review
MED13L Syndrome
MED13L syndrome is a developmental disorder characterized by developmental delay, intellectual disability, and minor differences in facial features. Additionally, some people with this condition have recurrent seizures (epilepsy) or heart abnormalities that are present from birth (congenital heart defects).
  • 2.3K
  • 24 Dec 2020
Topic Review
Peroxisomal Stress Response and Inter-Organelle Communication
Peroxisomes are single membrane-bound organelles found in all eukaryotic cells and organisms, from yeast to plants and mammals. They are key regulators of cellular and metabolic homeostasis. These organelles play important roles in redox metabolism, the oxidation of very-long-chain fatty acids (VLCFAs), and the biosynthesis of ether phospholipids. Given the essential role of peroxisomes in cellular homeostasis, peroxisomal dysfunction has been linked to various pathological conditions, tissue functional decline, and aging. In the past few decades, a variety of cellular signaling and metabolic changes have been reported to be associated with defective peroxisomes, suggesting that many cellular processes and functions depend on peroxisomes. Peroxisomes communicate with other subcellular organelles, such as the nucleus, mitochondria, endoplasmic reticulum (ER), and lysosomes. These inter-organelle communications are highly linked to the key mechanisms by which cells surveil defective peroxisomes and mount adaptive responses to protect them from damages. 
  • 2.3K
  • 15 Feb 2022
Topic Review
Computer Emergency Response Team
A computer emergency response team (CERT) is an expert group that handles computer security incidents. Alternative names for such groups include computer emergency readiness team and computer security incident response team (CSIRT).
  • 2.3K
  • 31 Oct 2022
Topic Review
Synthesis and Properties of Deep Eutectic Solvents
The use of deep eutectic solvents (DES) is on the rise worldwide because of the astounding properties they offer, such as simplicity of synthesis and utilization, low-cost, and environmental friendliness, which can, without a doubt, replace conventional solvents used in heaps.
  • 2.3K
  • 04 Jul 2023
Topic Review
Class Imbalance Problem in Credit Risk Prediction
Credit, as defined by financial institutions such as banks and lending companies, represents a vital loan certificate issued to individuals or businesses. This certification mechanism plays a pivotal role in ensuring the smooth functioning of the financial sector, contingent upon comprehensive evaluations of creditworthiness.
  • 2.3K
  • 18 Mar 2024
Topic Review
Fusarium graminearum Pigments and Compounds
Fusarium graminearum (teleomorph: Gibberella zeae) is a pathogen of maize, wheat, rice, and barley responsible for the disease known as Fusarium head blight (FHB) and mycotoxin contamination. Several studies have explored in depth the biochemistry and genetics of the pigments present in Fusarium graminearum. Still, there is a need to discuss their relationship with the mold’s observable surface color pattern variation throughout its lifecycle. 
  • 2.3K
  • 07 Jul 2021
Topic Review
Renewable Energy in Iran
Despite Iran’s diverse potentials in the field of renewable energy, wind energy has a higher priority than other cases in terms of economic justification and market competition, and domestic production rates. Other renewable energy sources for power generation and grid connection are less of a priority for short- or medium-term investment. However, for non-grid use in the country, they can also be very useful in the short term. In general, Iran can be a hub for renewable energy.
  • 2.3K
  • 22 Feb 2022
Topic Review
Mechanisms of Synaptic Vesicle Exo- and Endocytosis
Within 1 millisecond of action potential arrival at presynaptic terminals voltage–gated Ca2+ channels open. The Ca2+ channels are linked to synaptic vesicles which are tethered by active zone proteins. Ca2+ entrance into the active zone triggers: (1) the fusion of the vesicle and exocytosis, (2) the replenishment of the active zone with vesicles for incoming exocytosis, and (3) various types of endocytosis for vesicle reuse, dependent on the pattern of firing. These time-dependent vesicle dynamics are controlled by presynaptic Ca2+ sensor proteins, regulating active zone scaffold proteins, fusion machinery proteins, motor proteins, endocytic proteins, several enzymes, and even Ca2+ channels, following the decay of Ca2+ concentration after the action potential. 
  • 2.3K
  • 13 Jul 2022
Topic Review
The Microbiota–Gut–Brain Axis in Psychiatric Disorders
The microbiota is a group of microorganisms that colonize the human body, and the composition of this group is not accidental; in turn, the term microbiome covers the genomes of all microorganisms in a particular environment. This complex ecosystem is characterized by a complicated network of positive and negative interrelationships that significantly impact the host’s health. Notably, the microbiota currently depends not only on the interdependencies occurring in this specific ecosystem but also on the cells of the macroorganism. Microorganisms inhabit various areas of the human body, ranging from the skin, through the mouth, the upper respiratory tract, the ear canal, and the vagina. However, 90% of all microorganisms colonize the initial sections of the small and large intestines. Many data indicate that the number of microorganisms that inhabit a macroorganism exceeds ten times the number of its cells.
  • 2.3K
  • 13 Oct 2022
Topic Review
APT
Advanced package tool, or APT, is a free-software user interface that works with core libraries to handle the installation and removal of software on Debian, and Debian-based Linux distributions. APT simplifies the process of managing software on Unix-like computer systems by automating the retrieval, configuration and installation of software packages, either from precompiled files or by compiling source code.
  • 2.3K
  • 21 Oct 2022
Topic Review
ArchiCAD
ARCHICAD is an architectural BIM CAD software for Macintosh and Windows developed by the Hungarian company Graphisoft. ARCHICAD offers computer aided solutions for handling all common aspects of aesthetics and engineering during the whole design process of the built environment — buildings, interiors, urban areas, etc. Development of ARCHICAD started in 1982 for the Apple Lisa, the predecessor of the original Apple Macintosh. Following its launch in 1987, with Graphisoft's "Virtual Building" concept, ARCHICAD became regarded by some as the first implementation of BIM. ARCHICAD has been recognized as the first CAD product on a personal computer able to create both 2D and 3D geometry, as well as the first commercial BIM product for personal computers and considered "revolutionary" for the ability to store large amounts of information within the 3D model. Today, it has over 120,000 users.
  • 2.3K
  • 11 Nov 2022
Topic Review
R1234yf in Organic Rankine Cycle
ORC technology is one of the most promising technologies for the use of residual energy in the generation of electrical energy, offering simple and environmentally friendly alternatives. In this field, the selection of working fluids plays an important role in the operation of the cycle, whether in terms of the energy efficiency or the minimization of environmental impacts. 
  • 2.3K
  • 09 Jun 2021
Topic Review
Blood Neurofilament Light Chain
Neurofilament light chain (NfL) is a neuron specific structural protein which can be detected in the blood (serum and plasma). Elevate blood levels may serve as an important surrogate neuro-axonal injury in a variety of neurological conditions, already showing promising associations with outcomes of interest.
  • 2.3K
  • 26 Nov 2020
Topic Review
Value-Free Analysis of Values
The Culture-Based Development (CBD) approach suggests that the value-free analysis of values needs: (i) to use positive methods to classify a value as local or universal; (ii) to examine the existence of what is termed the Aristotelian Kuznets curve of values (i.e., to test for the presence of an inflection point in the economic impact from the particular value) and (iii) to account for Platonian cultural relativity (i.e., the cultural embeddedness expressed in the geographic nestedness of the empirical data about values). In short, the value-free analysis of values is a novel methodological protocol that ensures an accurate and precise analysis of the impact from a particular cultural value on a specific socio-economic outcome of interest.  
  • 2.3K
  • 21 Dec 2020
Topic Review
Strategies to Cope with Late Wilt of Maize
Zea mays L. (maize, corn) is one of the world’s leading crops for food, feed, and fuel and as a raw material for different industrial products. Control of maize late wilt disease (LWD) has been at the forefront of research efforts since the discovery of the disease in the 1960s. The disease has become a major economic restraint in highly affected areas such as Egypt and Israel and is of constant concern in other counties. LWD causes dehydration and collapsing at a late stage of maize cultivation, starting from the male flowering phase. The disease causal agent, Magnaporthiopsis maydis, is a seed- and soil-borne phytoparasitic fungus, penetrating the roots at sprouting, colonizing the vascular system without aboveground symptoms, and spreading upwards in the xylem, eventually blocking the water supply to the plant’s upperparts. Nowadays, the disease’s control relies mostly on identifying and developing resistant maize cultivars. Still, host resistance can be limited because M. maydis undergoes pathogenic variations, and virulent strains can eventually overcome the host immunity. This alarming situation is driving researchers to continue to seek other control methods. The current entry will summarize the various strategies tested over the years to minimize the disease damage. These options include agricultural (crop rotation, cover crop, no-till, flooding the land before sowing, and balanced soil fertility), physical (solar heating), allelochemical, biological, and chemical interventions. Some of these methods have shown promising success, while others have contributed to our understanding of the disease development and the environmental and host-related factors that have shaped its outcome. The most updated global knowledge about LWD control will be presented, and knowledge gaps and future aims will be discussed.
  • 2.3K
  • 10 Jan 2022
Topic Review
Measuring the Sustainability of the Orange Economy
Creative and cultural activities, more recently encompassed in the Orange economy, have been the subject of great interest in recent decades. They have been attributed great potential as engines of economic growth and sustainable development, a role that has been encouraged by various international organizations. There has been much commentary on the important capacity of the creative and cultural sector to generate sustainable growth from the triple economic, social, and environmental perspective. Accepting this premise, there is a commitment to the creative and the cultural economy that is manifested in the proposal and the implementation of various economic policy measures.
  • 2.3K
  • 25 Mar 2022
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