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Topic Review
Deep Learning Applications for Optical Coherence Tomography
With non-invasive and high-resolution properties, optical coherence tomography (OCT) has been widely used as a retinal imaging modality for the effective diagnosis of ophthalmic diseases. The retinal fluid is often segmented by medical experts as a pivotal biomarker to assist in the clinical diagnosis of age-related macular diseases, diabetic macular edema, and retinal vein occlusion. In recent years, the advanced machine learning methods, such as deep learning paradigms, have attracted more and more attention from academia in the retinal fluid segmentation applications. The automatic retinal fluid segmentation based on deep learning can improve the semantic segmentation accuracy and efficiency of macular change analysis, which has potential clinical implications for ophthalmic pathology detection.
  • 2.4K
  • 07 May 2022
Topic Review
1978–79 Boston College Basketball Point Shaving Scandal
The 1978–79 Boston College basketball point shaving scandal involved a scheme in which members of the American Mafia recruited and bribed several Boston College Eagles men's basketball players to ensure the team would not win by the required margin (not cover the point spread), allowing the gamblers in the know to place wagers against that team and win.
  • 2.4K
  • 08 Nov 2022
Topic Review
Economic Policy of the Indira Gandhi Premiership
The economic policy of the Indira Gandhi premiership was characterized by moderate tax increases on higher income Indians, bank nationalisation, green revolution. Gandhi presided over three Five-Year Plans as Prime Minister, two of which succeeded in meeting the targeted growth. There is considerable debate regarding whether Gandhi was a socialist on principle or out of political expediency. Sunanda K. Datta-Ray described her as "a master of rhetoric...often more posture than policy", while The Times journalist, Peter Hazelhurst, famously quipped that Gandhi's socialism was "slightly left of self-interest." Critics have focused on the contradictions in the evolution of her stance towards communism; Gandhi being known for her anti-communist stance in the 1950s with Meghnad Desai even describing her as "the scourge of [India's] Communist Party." Yet, she later forged close relations with Indian communists even while using the army to break the Naxalites. In this context, Gandhi was accused of formulating populist policies to suit her political needs; being seemingly against the rich and big business while preserving the status quo in order to manipulate the support of the left at times of political insecurity, such as the late 1960s. Although Gandhi came to be viewed in time as the scourge of the right-wing and reactionary political elements of India, leftist opposition to her policies emerged. As early as 1969, critics had begun accusing her of insincerity and machiavellianism. The Indian Libertarian wrote that: "it would be difficult to find a more machiavellian leftist than Mrs Indira Gandhi...for here is Machiavelli at its best in the person of a suave, charming and astute politician." Rosser wrote that "some have even seen the declaration of emergency rule in 1975 as a move to suppress [leftist] dissent against Gandhi's policy shift to the right." In the 1980s, Gandhi was accused of "betraying socialism" after the beginning of Operation Forward, an attempt at economic reform. Nevertheless, others were more convinced of Gandhi's sincerity and devotion to socialism. Pankaj Vohra noted that "even the late prime minister's critics would concede that the maximum number of legislations of social significance was brought about during her tenure...[and that] she lives in the hearts of millions of Indians who shared her concern for the poor and weaker sections and who supported her politics." In summarizing the biographical works on Gandhi, Blema S. Steinberg concluded she was decidedly non-ideological. Only 7.4% (24) of the total 330 biographical extractions posit ideology as a reason for her policy choices. Steinberg noted Gandhi's association with socialism was superficial; only having a general and traditional commitment to the ideology, by way of her political and family ties. Gandhi personally had a fuzzy concept of socialism. In one of the early interviews she had given as Prime Minister, Gandhi had ruminated: "I suppose you could call me a socialist, but you have understand what we mean by that term...we used the word [socialism] because it came closest to what we wanted to do here – which is to eradicate poverty. You can call it socialism; but if by using that word we arouse controversy, I don't see why we should use it. I don't believe in words at all." Regardless of the debate over her ideology or lack of thereof, Gandhi remains a left-wing icon. She has been described by Hindustan Times columnist, Pankaj Vohra as "arguably the greatest mass leader of the last century." Her campaign slogan, Garibi Hatao ('Remove Poverty'), has become the iconic motto of the Indian National Congress. To the rural and urban poor, untouchables, minorities and women in India, Gandhi was "Indira Amma or Mother Indira."
  • 2.4K
  • 24 Nov 2022
Topic Review
Unix Philosophy
The Unix philosophy, originated by Ken Thompson, is a set of cultural norms and philosophical approaches to minimalist, modular software development. It is based on the experience of leading developers of the Unix operating system. Early Unix developers were important in bringing the concepts of modularity and reusability into software engineering practice, spawning a "software tools" movement. Over time, the leading developers of Unix (and programs that ran on it) established a set of cultural norms for developing software; these norms became as important and influential as the technology of Unix itself; this has been termed the "Unix philosophy." The Unix philosophy emphasizes building simple, short, clear, modular, and extensible code that can be easily maintained and repurposed by developers other than its creators. The Unix philosophy favors composability as opposed to monolithic design.
  • 2.4K
  • 08 Oct 2022
Topic Review
Hydrogen Energy in Russian
Solving production problems in the field of hydrogen energy, as well as ensuring the transportation of hydrogen raw materials with minimal losses, will allow in the foreseeable future to overcome the local scale of its capabilities and bring hydrogen energy to the international level, including replacing traditional gas or using it as a resource. In line with global trends, the development of hydrogen energy in the Russian Federation is taking place.
  • 2.4K
  • 06 Dec 2022
Topic Review
YOLO-Based Unmanned Aerial Vehicle Technology
YOLO-based unmanned aerial vehicle (UAV) technology is proposed in the context of interdisciplinary or multi-disciplinary collaborative research, by the cross-fertilization of You Only Look Once (YOLO) target detection algorithms and UAV technology. In this YOLO-based UAV technology, the UAV can provide more application scenarios for the YOLO algorithm, while the YOLO algorithm can assist the UAV with more novel tasks. The two can complement each other to further facilitate people's daily lives while contributing to the productivity of their respective industries.
  • 2.4K
  • 06 Apr 2023
Topic Review
Shear Thickening Mechanism
Shear thickening fluid (STF) is a dense colloidal suspension of nanoparticles in a carrier fluid in which the viscosity increases dramatically with a rise in shear rate. Due to the excellent energy absorption and energy dissipation of STF, there is a desire to employ STFs in a variety of impact applications.
  • 2.4K
  • 05 Jun 2023
Topic Review
Intelligent Buildings in Smart Grids
During the last decade, the smart grid (SG) concept has started to become a reality, mainly thanks to the technical progress achieved in telecommunications, informatics and power electronics, among other domains, leading to an evolution of the traditional electrical grid into an intelligent one. Nowadays, the SG can be seen as a system of smart systems that include cyber and physical parts from different technologies that interact with each other. In this context, intelligent buildings (IBs) constitute a paradigm in which such smart systems are able to guarantee the comfort of residents while ensuring an appropriate tradeoff of energy production and consumption by means of an energy management system (EMS).
  • 2.4K
  • 08 Jun 2021
Topic Review
Laccase
Enzymes play an important role in numerous natural processes and are increasingly being utilized as environmentally friendly substitutes and alternatives to many common catalysts. Both horseradish peroxidase (HRP) and laccase are most often utilized for the formation of enzyme aggregates due to their ability to rapidly oxidize phenols, generating phenoxy radicals which undergo radical coupling to form biphenyl or phenyl ether linkages. 
  • 2.4K
  • 07 Mar 2024
Topic Review
Spondylocostal Dysostosis (SCDO)
Spondylocostal dysostosis (SCDO) is a rare heritable congenital condition, characterized by multiple severe malformations of the vertebrae and ribs.
  • 2.4K
  • 18 Mar 2021
Topic Review
Cytotoxicity and Phagocytosis in Immunity
The immune system has evolved to protect organisms from infections caused by bacteria, viruses, and parasitic pathogens. In addition, it provides regenerative capacities, tissue maintenance, and self/non-self recognition of foreign tissues. In general, innate immunity is a fast and non-specific response associated with the presence of humoral and cellular elements. By contrast, adaptive immunity uses the induction of specialized cells such as B and T lymphocytes and molecules including the major histocompatibility complex (MHC), B-cell receptors (BCR), T-cell receptors (TCR), immunoglobulins (Ig), and antibodies to confer immunological memory and very high specificity thus fighting against a previously recognized infection. Both kinds of immune responses rely on two main cellular activities which are phagocytosis and cytotoxicity. These cellular immune mechanisms have been found at the earliest evolutionary stages of multicellular animals and diversified into a wide heterogeneous repertoire of effector cells through evolution.
  • 2.4K
  • 04 Aug 2021
Topic Review
Industry 4.0 Manufacturing Systems
Manufacturing systems are generally “physical” systems in a physical world. The internet is a cyber-world. The internet has allowed for global connectedness. At the same time, infused with this connectedness, is a “dark web.” The dark web constitutes malware, viruses, “ransomware-as-a-service,” and other divisive instruments. Industry 4.0 brings together in the form of “cyber-physical” systems a new range of opportunities for additive manufacturing. While the opportunity of connectedness maps, at the same time, the challenges of the “dark web” also maps into this world of manufacturing. On a growing basis, measures to improve cybersecurity continue to develop. These measures include the lever of machine and deep learning. In this entry, the authors use engineering control systems and other relevant theories, including augmented artificial intelligence, as a way of making more secure cyber-physical systems and thereby making practical the considerations for Industry 4.0.
  • 2.4K
  • 14 Apr 2021
Topic Review
Ag2O–MnO2/Graphene Oxide Nanocomposite
Catalytic oxidation of alcohol to their analogous carbonyls is one of the key organic reactions in both scientific and industrial applications, with universal production of 10,000 million tons/year of carbonyls in the 20th century. Such as, aldehyde and ketone derivatives are extensively employed as precursors in insecticide, flame-retardant, cosmetic, confectionery, flavoring, pharmaceutical, and beverage industries. 
  • 2.4K
  • 27 Oct 2020
Topic Review
Crop Management with the IoT
IoT is becoming a bearing technology for next generation crop management. Cheap networked devices can sense crop fields at a finer grain to give timeliness warnings on the presence of stress conditions and diseases, while on-board devices will monitor field and machine status. Cloud computing allows integrating collected information in a new  generation of FMIS to make decisions and automate field practices by actuators and robot fleets.
  • 2.4K
  • 02 Feb 2021
Topic Review
Deformation (Mechanics)
Deformation in continuum mechanics is the transformation of a body from a reference configuration to a current configuration. A configuration is a set containing the positions of all particles of the body. A deformation may be caused by external loads, body forces (such as gravity or electromagnetic forces), or changes in temperature, moisture content, or chemical reactions, etc. Strain is a description of deformation in terms of relative displacement of particles in the body that excludes rigid-body motions. Different equivalent choices may be made for the expression of a strain field depending on whether it is defined with respect to the initial or the final configuration of the body and on whether the metric tensor or its dual is considered. In a continuous body, a deformation field results from a stress field induced by applied forces or is due to changes in the temperature field inside the body. The relation between stresses and induced strains is expressed by constitutive equations, e.g., Hooke's law for linear elastic materials. Deformations which are recovered after the stress field has been removed are called elastic deformations. In this case, the continuum completely recovers its original configuration. On the other hand, irreversible deformations remain even after stresses have been removed. One type of irreversible deformation is plastic deformation, which occurs in material bodies after stresses have attained a certain threshold value known as the elastic limit or yield stress, and are the result of slip, or dislocation mechanisms at the atomic level. Another type of irreversible deformation is viscous deformation, which is the irreversible part of viscoelastic deformation. In the case of elastic deformations, the response function linking strain to the deforming stress is the compliance tensor of the material.
  • 2.4K
  • 20 Oct 2022
Topic Review
Thousand-Year Rose
The Thousand-year Rose (German: Tausendjähriger Rosenstock, literally: Thousand-year-old Rosebush) is also known as the Rose of Hildesheim. It grows on the apse of the Hildesheim Cathedral, a Catholic cathedral in Hildesheim, Germany, that is dedicated to the Assumption of Mary. The cathedral and the adjacent St. Michael's Church have been on the UNESCO list of World Heritage Sites since 1985. The rose that climbs on the wall of the cathedral's apse is believed to be the oldest living rose in the world. A Rosa canina, commonly known as a wild dog rose, grows against the eastern apse of the cathedral, which is around 21 metres (69 ft) high and 9 metres (30 ft) wide. The rose bush reaches a height of around 10 metres (33 ft) and documentation verifies its age at approximately 700 years. Slight variations arise in the tale of the establishment of the diocese by King Louis the Pious at Hildesheim in 815 but the rose bush is a common theme in all versions. The cathedral was destroyed by Allied bombers in 1945 during the Second World War, but the roots of the rose bush survived and it blossomed again among the ruins. According to legend, while the rose bush flourishes, Hildesheim will prosper. A poem about the rose was published in 1896. In the early twentieth century, after visiting the cathedral and seeing the rose, author Mabel Wagnalls was inspired to write a book, which went on to form the basis of a silent film.
  • 2.4K
  • 08 Nov 2022
Topic Review
Modes of Nanofertilizer Application
There are three primary methods of nanofertilizer application: foliar, seed nanopriming, and soil treatment. The appropriate method of nanofertilizer application is crucial for optimal plant growth, as it varies depending on the soil and climate type. The choice depends on soil quality, nutrient availability, and climate, which affect nutrient uptake and utilization. Understanding these factors and selecting the appropriate method can improve crop yield, reduce environmental impact, and create more sustainable agricultural practices.
  • 2.4K
  • 30 Jun 2023
Topic Review
RNA-Targeting CRISPR–Cas Systems
Many CRISPR–Cas systems have been used as a backbone for the development of potent research tools, with Cas9 being the most widespread. While most of the utilized systems are DNA-targeting, recently more and more attention is being gained by those that target RNA. Their ability to specifically recognize a given RNA sequence in an easily programmable way makes them ideal candidates for developing new research tools. 
  • 2.4K
  • 23 Dec 2020
Topic Review
Classification of Wine Phenolic Compounds
Phenolic compounds are secondary metabolites present in grapes and wine that can be formed and transformed during the winemaking process. Phenolics can be classified as flavonoids (e.g., anthocyanins, flavan-3-ols, flavonols) and non-flavonoids (e.g., phenolic acids, stilbenes).
  • 2.4K
  • 12 Apr 2021
Topic Review
Hybrid Electric Vehicles
According to the Society of Automotive Engineers, a hybrid vehicle can be defined as that vehicle with two or more energy storage systems which must provide power to the propellant system either together or independently. Similarly, the heavy duty hybrid vehicles group indicates that a hybrid vehicle must have at least two energy storage systems and energy converters. In practice, a hybrid electric vehicle (HEV) combines the great autonomy of conventional vehicles with spark ignition engines, compression ignition engines, fuel cells and solar panels with the speed, performance and environmental advantages of electric vehicles, obtaining an automobile with lower fossil fuel consumption and lower pollutant emissions to the atmosphere.
  • 2.4K
  • 10 Aug 2021
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