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Topic Review
The Surface of the Eye
Drug delivery to the internal ocular structures remains an important and relevant topic owing to the unique immune privileges of the eye which limit the success of systemic injections. The need to prevent and/or treat several common conditions, including age-related macular degeneration, endophthalmitis, retinal degeneration, diabetic retinopathy, and cataracts, has motivated the development of pharmaceuticals that require entry into the eye and extended residency to be most effective. The ocular surface is a surprisingly diverse portion of the eye, consisting of multiple tissues and glands. From a diagnostic standpoint, ocular surface disease may appear on the inside of the eyelid, on the cornea, on the conjunctiva, and in any of the associated glands. The ocular surface also offers an attractive option for drug delivery due to its relative ease of application and minimally invasive approach.
  • 2.5K
  • 24 May 2022
Topic Review
Solid Waste Management
Disposal of municipal solid waste (MSW) is one of the significant global issues that is more evident in developing nations. One of the key methods for disposing of the MSW is locating, assessing, and planning for landfill sites.  Due to rapidly expanding global urbanization, associated lack of resources, and inadequate urban waste management, MSW issues and management concerns are on the rise. Over a third of total municipal waste out of two billion tons generated remains uncollected worldwide. MSW is collected and disposed of at certain locations or burnt down in most developing nations. Landfill sites for solid waste must be inspected in terms of all requirements to reduce economic and environmental expenses.
  • 2.5K
  • 17 Jun 2022
Topic Review
Raj`a
Raj`a (Arabic: الرجعة) (alternatively rjaa, raja'a, raj'at) in Islamic terminology, refers to the Second Coming, or the return to life of a given past historical figure after that person's physical death. While primarily used in Shia Muslim terminology, variations on the doctrine exist in Sunni Islam and the Bahá'í Faith, and raj`a is used to describe certain Christian doctrines in Arabic.
  • 2.5K
  • 06 Oct 2022
Topic Review
Inflammation of the Lips (Cheilitis) and Perioral Skin
Lip inflammation may manifest as mainly reversible cheilitis, mainly irreversible, or cheilitis connected to dermatoses or systemic diseases. Therefore, knowing a patient’s medical history is important, especially whether their lip lesions are temporary, recurrent, or persistent. Sometimes temporary contributing factors, such as climate and weather conditions, can be identified and avoided—exposure to extreme weather conditions (e.g., dry, hot, or windy climates) may cause or trigger lip inflammation. Emotional and psychological stress are also mentioned in the etiology of some lip inflammations (e.g., exfoliative cheilitis) and may be associated with nervous habits such as lip licking. 
  • 2.5K
  • 12 Jan 2023
Topic Review
Ultrasonic and UWB Technology for Indoor Localization
Evaluations of different technologies and solutions for indoor localization exist but only a few are aimed at the industrial context. It's showed that an acceptable accuracy required for tracking people or objects and could serve as a guideline for the least achievable accuracy when applied for mobile robotics in conjunction with other elements of a robotic navigation stack. 
  • 2.5K
  • 12 Jun 2022
Topic Review
Eye Diseases Associated with Oral Pathogens
Even before the advancement of sophisticated molecular biology techniques, eye diseases were regarded as manifestations of infections in the mouth. A few of the ancient studies interrelated the resolution of the given disease upon elimination of oral sepsis by extraction of the infected teeth. In this context, bacteria and or their toxic metabolites and reflex nervous irritation were considered to be the crucial factors. In successive years, the concept of “oral foci of infection” lost its attention. Nonetheless, there are many studies successively acknowledged periodontitis as a risk factor in the pathogenesis of assorted inflammatory eye diseases including scleritis, iritis, glaucoma, diabetic retinopathy (DR), uveitis, retinitis pigmentosa (RP), and Sjogren syndrome (SS).
  • 2.5K
  • 27 Jun 2022
Topic Review
WEC with Linear Generator-Based Direct Electric-Drive PTO System
The traditional wave energy converters (WECs) use hydraulic or turbine-type power take-off (PTO) mechanisms which consist of many moving parts, creating mechanical complexity and increasing the installation and maintenance costs. Linear generator-based direct-drive WECs could be a solution to overcome this problem. 
  • 2.5K
  • 01 Sep 2022
Topic Review Peer Reviewed
COVID-19’s Financial Impact on UK Football Clubs
This entry explores the financial impact of the COVID-19 pandemic on the football industry, highlighting the challenges, adaptations, and long-term implications for clubs across all levels. It examines the industry’s financial fragility, particularly for clubs reliant on matchday revenue, while showcasing adaptive strategies such as digital engagement, government support, and revenue diversification that sustained operations during the crisis. The pandemic exposed structural vulnerabilities within football, from elite clubs to grassroots teams, through revenue shortfalls caused by closed stadiums, cancelled matches, and reduced sponsorships. This study provides a comprehensive analysis of the pandemic’s effects on revenue streams, fixed costs, player contracts, and stakeholder roles, offering insights into strategies that promote financial resilience. Case studies illustrate how elite, semi-professional, and grassroots clubs responded to financial and operational challenges, emphasising the importance of diversified income sources, proactive financial planning, and community support. By identifying lessons from the pandemic, the entry underscores the critical need for sustainable practises and resilient models to prepare the football industry for future disruptions.
  • 2.5K
  • 06 Feb 2025
Topic Review
Human Emotion Recognition
Automated emotion recognition (AEE) is important issue in the various field of activities, which uses human emotional reaction as a signal for marketing, technical equipment or human-robot interaction. Paper analyzes vast layer of scientific research and technical papers for sensor use analysis, where various methods implemented or researched. Paper cover few classes of sensors, using contactless methods, contact and skin-penetrating electrodes with for human emotion detection and measurement of their intensity. Result of performed analysis in this paper presented applicable methods for each type of emotions or their intensity and proposed their classification. Provided classification of emotion sensors revealed area of application and expected outcome from each method as well as noticed limitation of them. This paper should be interested for researchers, needed to use of human emotion evaluation and analysis, when there is a need to choose proper method for their purposes or find alternative decision.
  • 2.5K
  • 27 Jan 2021
Topic Review
Nonsense-Mediated mRNA Decay
Nonsense-mediated messenger RNA (mRNA) decay (NMD) is a surveillance pathway used by cells to control the quality mRNAs and to fine-tune transcript abundance. NMD plays an important role in cell cycle regulation, cell viability, DNA damage response, while also serving as a barrier to virus infection. Disturbance of this control mechanism caused by genetic mutations or dys-regulation of the NMD pathway can lead to pathologies, including neurological disorders, immune diseases and cancers. The role of NMD in cancer development is complex, acting as both a promoter and a barrier to tumour progression. Cancer cells can exploit NMD for the downregulation of key tumour suppressor genes, or tumours adjust NMD activity to adapt to an aggressive immune microenvironment.
  • 2.5K
  • 22 Sep 2021
Topic Review
Renewable Energy Policies in Iran
The National Renewable Energy Policy can be introduced as an important step in increasing the investment and extraction of renewable energy in the total energy mix. Furthermore, to increase the use of local renewable energy sources, increasing the share of renewable energy in the composition of electricity generation can be achieved through facilitating the growth of the renewable industry, ensuring the reasonable cost of renewable energy production and creating public awareness of the importance of sustainable energy and clean technology.
  • 2.5K
  • 26 Jul 2021
Topic Review
Climate of the Alps
The climate of the Alps is the climate, or average weather conditions over a long period of time, of the exact middle Alpine region of Europe. As air rises from sea level to the upper regions of the atmosphere the temperature decreases. The effect of mountain topography on prevailing winds is to force warm air from the lower region into an upper zone where it expands in volume at the cost of a proportionate loss of heat, often accompanied by the precipitation of moisture in the form of snow, rain or hail. The position of the Alps in the central European continent profoundly affects the climate of all the surrounding regions. The accumulation of vast masses of snow, which have gradually been converted into permanent glaciers, maintains a gradation of very different climates within the narrow space that intervenes between the foot of the mountains and their upper ridges; it cools breezes that waft to the plains on either side, but its most important function is to regulate the water supply of the large region which is traversed by the streams of the Alps. Nearly all the moisture that is precipitated during fall, winter, and spring is stored in the form of snow and gradually diffused in the course of the succeeding summer; even in the hottest and driest seasons the reserves accumulated during a long preceding period of years in the form of glaciers are available to maintain the regular flow of the greater streams. Nor is this all; the lakes that fill several of the main valleys on the southern side of the Alps are somewhat above the level of the plains of Lombardy and Venetia, and afford an inexhaustible supply of water, which, from a remote period, has been used for that system of irrigation to which they owe their proverbial fertility. Six regions or zones, which are best distinguished by their characteristic vegetation, are found in the Alps. It is an error to suppose that these are indicated by absolute height above sea level. Local conditions of exposure to the Sun, protection from cold winds, or the reverse, are of primary importance in determining the climate and the corresponding vegetation.
  • 2.5K
  • 28 Nov 2022
Topic Review
Tithonia Diversifolia
Tithonia diversifolia　（Hemsl.） A. Gray　(Asteraceae) is native to Mexico and Central America. The species is spreading quickly and has naturalized in more than 70 countries. It has often been recorded as a harmful invasive plant which disturbs native plant communities. Phytotoxic chemical interactions such as allelopathy between invasive plants and native plants have been reported to play an important role in the invasion. Evidence for allelopathy of T. diversifolia has accumulated in the literature over 30 years. Thus, the objective of this review was to discuss the possible involvement of allelopathy in the invasive potential of T. diversifolia. The extracts, root exudates and plant residues of T. diversifolia inhibited the germination and growth of other plant species. The soil-water and soil collected from T. diversifolia fields also shown growth inhibitory effects. The decomposition rate of T. diversifolia residues in soil was reported to be high. Phytotoxic substances such as sesquiterpene lactones were isolated and identified in the extracts of T. diversifolia. Some of phytotoxic substances in T. diversifolia may be released into the soil through the decomposition of the plant residues and the exudation from living tissues of T. diversifolia including its root exudates, and act as allelopathic substances. Those allelopathic substances can inhibit the germination and growth of neighboring plants, and may enhance the competitive ability of the plants and make the plants invasive.
  • 2.5K
  • 27 Oct 2020
Topic Review
In-Vitro Gas Production Technique
The in vitro gas production technique, either based on volume or pressure measurements, was initially set up for the evaluation of the rate and extent of fermentation of feeds for ruminants. Since it is carried out under pH conditions simulating a well-bu ered medium (from pH 6.5 to 6.8), it has been generally focused to evaluation of forages and fibrous by-products, or by estimating fermentation of concentrate feeds (cereals, protein sources) for extrapolation of their use in mixed diets. However, it has also been used for determination of the nutritive value of feeds in all-concentrate diets, without taking into account that in such cases pH may range between 6.5 and 5.8, and often below this range, creating unfavourable conditions for bacterial fermentation. Modifying the concentration of bicarbonate ion in the incubation solution allows to adjust the incubation pH to conditions that simulate the in vitro fermentation conditions to those occurring under high-concentrate feeding. This highlights the importance of the incubation pH for the estimation of fermentation of feeds.
  • 2.5K
  • 24 Nov 2020
Topic Review
Clavulanic Acid
Clavulanic acid is an irreversible β-lactamase enzyme inhibitor with a weak antibacterial activity produced by the filamentous actinomycete Streptomyces clavuligerus (S. clavuligerus) and, in a lesser extent, by other streptomyces species. Clavulanic acid is typically co-formulated with broad-spectrum β‑lactam antibiotics such as amoxicillin and ticarcillin, conferring them high potential to treat infectious diseases caused by β‑lactam-resistant bacteria like Escherichia coli, Staphylococcus aureus, Neisseria gonorrhoeae and Streptococcus pneumonia.
  • 2.5K
  • 22 Sep 2021
Topic Review
Pet Ownership and Quality of Life
Pet ownership is the most common form of human–animal interaction, and anecdotally, pet ownership can lead to improved physical and mental health for owners. The entry summarizes the literature to determine the evidence for the role pets play in quality of life for their owners. 
  • 2.5K
  • 21 Jan 2022
Topic Review
Television Network
A television network or broadcaster is a telecommunications network for distribution of television program content, whereby a central operation provides programming to many television stations or pay television providers. Until the mid-1980s, television programming in most countries of the world was dominated by a small number of terrestrial networks. Many early television networks (such as the BBC, NBC or CBC) evolved from earlier radio networks.
  • 2.5K
  • 01 Nov 2022
Topic Review
Protection of Iron by Corrosion Inhibitors
Iron is a widely used metal due to its low cost and availability, but it is susceptible to corrosion in many circumstances. This corrosion can result in economic and environmental losses, and negatively affect the physical and chemical properties of the metal.
  • 2.5K
  • 24 Mar 2023
Topic Review
Polyphenol-Rich Dry Common Beans and Their Health Benefits
Polyphenols are plant metabolites with potent anti-oxidant properties, which help to reduce the effects of oxidative stress-induced dreaded diseases. The evidence demonstrated that dietary polyphenols are of emerging increasing scientific interest due to their role in the prevention of degenerative diseases in humans. Possible health beneficial effects of polyphenols are based on the human consumption and their bioavailability. Common beans (Phaseolus vulgaris L.) are a greater source of polyphenolic compounds with numerous health promoting properties. Polyphenol-rich dry common beans have potential effects on human health, and possess anti-oxidant, anti-diabetic, anti-obesity, anti-inflammatory and anti-mutagenic and anti-carcinogenic properties.
  • 2.5K
  • 07 Oct 2023
Topic Review
Wheat Gluten and Gluten-Free Alternatives
Gluten is the nitrogen storage protein matrix found in wheat and cereals belonging to the Triticeae tribe, and it is composed of two proteins: gliadin and glutenin.
  • 2.5K
  • 28 Jan 2021
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