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Topic Review
Evidence of Disaster Planning by Home Care Providers
The increasing risk of disasters worldwide poses challenges both to health care infrastructures and to home care providers, who must maintain decentralised services for those in need of long-term care for as long as possible, even under adverse circumstances. However, both the kind of organisational precautions that home care providers consider in preparation for disasters and the available evidence on the effectiveness of these precautions remain largely unclear.
  • 625
  • 22 May 2023
Topic Review
Self-Attachment to Treat Chronic Anxiety and/or Depression
Anxiety and depression are debilitating conditions which, together with substance abuse, are considered globally to represent the most common psychological disorders; they are correlated with each other and are also common features of many severe psychological disorders. Attachment theory was introduced by John Bowlby in the 1960s and 1970s and has since developed into a main paradigm in developmental psychology with wide impact in many related areas including psychotherapy.
  • 624
  • 28 Jun 2022
Topic Review
Research Trends of Physical Activity during Pregnancy
Physical activity (PA) during pregnancy has been proven beneficial to pregnant women, with a significant effect on ameliorating many severe gestational complications. Improvement of sedentary behaviour, lifestyle intervention through leisure-time PA, and preterm care are major research frontiers and have received extensive attention. 
  • 623
  • 21 Nov 2022
Topic Review
Lifestyle and Pain following Cancer
Cancer Survivor (CS), the most widely used definition is: “being a CS, starts on the day of diagnosis and continues until the end of life. Three cancer survivorship phases can be distinguished: “acute survivorship” (i.e., early-stage or time during curative treatment), “permanent survivorship” (i.e., living with cancer or also called the palliative stage), and “extended survivorship” (i.e., cured but not free of suffering). Chronic pain is one of these and occurs in 40% of CSs. Chronic pain is defined by the International Association for the Study of Pain (IASP) as pain that persists or recurs for longer than three month. Unrelieved pain can have considerable adverse consequences on a CSs’ quality of life.
  • 619
  • 07 Jan 2022
Topic Review
Forest Therapy Programs for Stress Reduction
Forest therapy programs were effective at relieving stress, particularly on a psychological level. Forest therapy programs could be used as a part of stress reduction projects. 
  • 617
  • 23 Oct 2023
Topic Review
Mechanism of Monkeypox Disease
The past have witnessed an appalling rise in several emerging and re-emerging viral and zoonotic outbreaks. Such outbreaks are a lesson to learn from and seek insight into better disease monitoring and surveillance, thus preventing future outbreaks. Monkeypox, a viral zoonotic illness caused by the monkeypox virus, may no longer be endemic to the tropical rainforests of Central and West Africa. However, the monkeypox outbreak in nonendemic countries is most likely due to failure to curb the disease dissemination in endemic African regions despite constant outbreaks. The clinical manifestations are typified by a prodromal phase (fever, myalgia, malaise, and lymphadenopathy) followed by maculopapular or vesicular, or pustular cutaneous eruptions that eventually form encrustations and peel off. Children and the elderly, pregnant females, and individuals living with comorbidities (diabetes, HIV/AIDS, and lymphoproliferative ailments) are at a high risk of severe disease. Monkeypox is a self-limiting disorder, but its complications and pandemic potential signify its immense public health relevance. The ongoing monkeypox outbreak in nonendemic nations areas was identified with increased propensity in men who have sex with men (MSMs) with no travel history to endemic regions, emphasizing the changing trends in disease transmission. 
  • 616
  • 24 Nov 2022
Topic Review
Artificial Intelligence in Breast Cancer Medical Imaging
The heavy global burden and mortality of breast cancer emphasize the importance of early diagnosis and treatment. Imaging detection is one of the main tools used in clinical practice for screening, diagnosis, and treatment efficacy evaluation, and can visualize changes in tumor size and texture before and after treatment. The overwhelming number of images, which lead to a heavy workload for radiologists and a sluggish reporting period, suggests the need for computer-aid detection techniques and platform. In addition, complex and changeable image features, heterogeneous quality of images, and inconsistent interpretation by different radiologists and medical institutions constitute the primary difficulties in breast cancer screening and imaging diagnosis. The advancement of imaging-based artificial intelligence (AI)-assisted tumor diagnosis is an ideal strategy for improving imaging diagnosis efficient and accuracy. By learning from image data input and constructing algorithm models, AI is able to recognize, segment, and diagnose tumor lesion automatically, showing promising application prospects. Furthermore, the rapid advancement of “omics” promotes a deeper and more comprehensive recognition of the nature of cancer.
  • 610
  • 03 Feb 2023
Topic Review
Regulation of Dietary Energy Intake
Obesity is one of the most important factors responsible for the marked increase in both the incidence and prevalence of type 2 diabetes mellitus (T2DM) in recent decades. Addressing the lifestyle factors associated with the progression to T2DM would present a potential rational early prevention strategy. 
  • 602
  • 28 Feb 2023
Topic Review
Theoretical Rationale of Fall Prevention Exercise Program
Falls are a major concern in the elderly and walking is an important daily activity in which falls occur, with tripping and slipping being the most frequent causes. Gait biomechanical parameters have been related to the occurrence of falls in the elderly. Moreover, there is evidence that falls can be prevented through exercise programs, which have been shown to be also effective in improving gait biomechanical parameters.
  • 600
  • 29 Jan 2024
Topic Review
Rehabilitation of Motor Impairment in Stroke
Stroke is categorized as one of the most concerning global health issues as it is a serious and common disabling factor worldwide. Ageing and urbanization are two powerful drivers of stroke. The elderly population is at higher risk of experiencing a stroke, but stroke can be prevented to some extent by dealing with the modifiable menace factors such as physical inactivity, drugs, unhealthy diet, and tobacco so that problems such as hypertension, high blood pressure, and diabetes, which are the root causes of the epidemic, may be managed. Different therapies are described, such as functional electric stimulation (FES), noninvasive brain stimulation (NIBS) including transcranial direct current stimulation (t-DCS) and transcranial magnetic stimulation (t-MS), invasive epidural cortical stimulation, virtual reality (VR) rehabilitation, task-oriented therapy, robot-assisted training, tele rehabilitation, and cerebral plasticity for the rehabilitation of upper extremity motor impairment. New therapeutic rehabilitation techniques are also being investigated, such as VR. 
  • 599
  • 11 Feb 2022
Topic Review
Gender Differences in the Diagnosis of Dyslipidemia
Evidence shows that objectives for detecting and controlling dyslipidemia are not being effectively met, and outcomes differ between men and women.
  • 596
  • 10 Dec 2021
Topic Review
Urgent Threat of Infections by Antimicrobial Resistant Bacteria
Infectious disease outbreaks have caused thousands of deaths and hospitalizations, along with severe negative global economic impacts. Among these, infections caused by antimicrobial-resistant microorganisms are a major growing concern. The misuse and overuse of antimicrobials have resulted in the emergence of antimicrobial resistance (AMR) worldwide. Carbapenem-resistant Enterobacterales (CRE) are among the bacteria that need urgent attention globally. The emergence and spread of carbapenem-resistant bacteria are mainly due to the rapid dissemination of genes that encode carbapenemases through horizontal gene transfer (HGT). The rapid dissemination enables the development of host colonization and infection cases in humans who do not use the antibiotic (carbapenem) or those who are hospitalized but interacting with environments and hosts colonized with carbapenemase-producing (CP) bacteria. There are continuing efforts to characterize and differentiate carbapenem-resistant bacteria from susceptible bacteria to allow for the appropriate diagnosis, treatment, prevention, and control of infections.
  • 596
  • 04 Jul 2023
Topic Review
AI for Biomarker Analysis in Early Cancer Detection
Governments worldwide have prioritized multicancer early detection (MCED) for the better management of cancers. Artificial intelligence (AI) is a promising technology to enhance the performance of MCED. In the field of MCED, applying AI has also proven to be efficient in improving diagnostic performance. Harnessing AI has become a must-use technology in analyzing MCED data because MCED tools typically target tens of analytical targets. 
  • 592
  • 29 Feb 2024
Topic Review
Decrease Death Rate of Neonates
Neglected diseases still kill and disable too many, but no age group has in this regard received less attention than newborns. A newborn or neonate is a human from age 0 to 28 days. Worldwide, their contribution to death and disease is overwhelming and unequaled by any condition, while at the same time, its prevention and treatments are simple, relatively cheap, and efficient. 
  • 589
  • 12 May 2022
Topic Review
Life of Palliative Care Professionals during the COVID-19
The display of compassionate care by palliative care professionals is of the utmost importance to the patients, their families, and even to their own professional well-being. Lately and, especially due to the emergence of the COVID-19 pandemic, palliative care professionals have been subjected to greater pressures stemming from their work environment, organizational standpoint, and emotional sense of view. Not only have these factors made it harder for professionals to deliver compassionate care to their patients, but they have also decreased their overall well-being.
  • 589
  • 09 Jan 2024
Topic Review
Associations between Childhood Abuse and Adult Psychopathology
Research consistently shows that abuse during childhood is related to adult psychopathology. Adverse childhood experiences, including emotional, physical, and sexual abuse, have been consistently linked to mental health problems in children and adults.
  • 588
  • 05 Mar 2024
Topic Review
Radon and Non-Pulmonary Neoplasm Risk
Although Radon (Rn) is a known agent for lung cancer, the link between Rn exposure and other non-pulmonary neoplasms remains unclear. The aim of this review is to investigate the role of Rn in the development of tumors other than lung cancer in both occupational and environmental exposure.  
  • 586
  • 22 Oct 2021
Topic Review
Displacement-Based Approaches for Protein-Bound Uremic Toxins Removal
End-stage renal disease (ESRD) patients rely on renal replacement therapies to survive. Hemodialysis (HD), the most widely applied treatment, is responsible for the removal of excess fluid and uremic toxins (UTs) from blood, particularly those with low molecular weight (MW < 500 Da). The development of high-flux membranes and more efficient treatment modes, such as hemodiafiltration, have resulted in improved removal rates of UTs in the middle molecular weight range. However, the concentrations of protein-bound uremic toxins (PBUTs) remain essentially untouched. Due to the high binding affinity to large proteins, such as albumin, PBUTs form large complexes (MW > 66 kDa) which are not removed during HD and their accumulation has been strongly associated with the increased morbidity and mortality of patients with ESRD. 
  • 585
  • 22 May 2023
Topic Review
Cervical Cancer Detection
Cervical cancer is a common and preventable disease that poses a significant threat to women’s health and well-being. It is the fourth most prevalent cancer among women worldwide, with approximately 604,000 new cases and 342,000 deaths in 2020, according to the World Health Organization. 
  • 585
  • 08 Oct 2023
Topic Review
Fitness Costs Antibiotic Resistance in the Gut
The acquisition of antibiotic resistance by horizontal gene transfer and by mutational changes in the chromosome or genes located in mobile genetic elements, followed by antibiotic resistance phenotype expression, implies modification of the cellular physiological status, including homeostatic adaptations of the previously susceptible cell.
  • 583
  • 26 Feb 2024
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