Topic Review
Generations of Glucose Biosensors
Electrochemical glucose biosensors are widely applied for glucose monitoring due to their unbeatable sensitivity, selectivity, and simplicity. In general, there are four primary generations of glucose biosensor, which are classified according to the electron transfer mechanism. Three generations represent the enzymatic glucose biosensor, and one generation represents the non-enzymatic glucose biosensor.
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  • 14 Dec 2022
Topic Review
Rice Bran
Rice (Oryza sativa) bran is the main commercial by-product of rice grain milling. It is a multilayer fraction composed by the most external tissues of the rice caryopsis. It is produced in large quantities worldwide and its composition is mainly related to insoluble dietary fibres, lipids and other nutrients and bioactive compounds with significant health-related properties.
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  • 09 Feb 2021
Topic Review
Meat Extenders
Meat extenders are non-meat substances with high protein contents used to partially substitue (or extend) the meat content in meat products. Initially devised to reduce costs (as meat is the most expensive ingredient in meat products) they can become now a useful strategy to develop more sustainable and healthier meat products.
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  • 28 Aug 2020
Topic Review
Brilliant Blue FCF
Brilliant Blue FCF (Blue 1) is a synthetic organic compound used primarily as a blue colorant for processed foods, medications, dietary supplements, and cosmetics. It is classified as a triarylmethane dye and is known under various names, such as FD&C Blue No. 1 or Acid Blue 9. It is denoted by E number E133 and has a color index of 42090. It has the appearance of a blue powder and is soluble in water and glycerol, with a maximum absorption at about 628 nanometers. It is one of the oldest FDA-approved color additives and is generally considered nontoxic and safe.
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  • 17 Nov 2022
Topic Review
Risk-Acceptance Criteria
The utilization of risk acceptance criteria (RAC) can help a business to judge whether the risk level concerning any process involved in its working environment is acceptable or not, especially when the risk has a significant societal impact.
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  • 28 Mar 2022
Topic Review
ICO (File Format)
The ICO file format is an image file format for computer icons in Microsoft Windows. ICO files contain one or more small images at multiple sizes and color depths, such that they may be scaled appropriately. In Windows, all executables that display an icon to the user, on the desktop, in the Start Menu, or in Windows Explorer, must carry the icon in ICO format. The CUR file format is an almost identical image file format for non-animated cursors in Microsoft Windows. The only differences between these two file formats are the bytes used to identify them and the addition of a hotspot in the CUR format header; the hotspot is defined as the pixel offset (in x,y coordinates) from the top-left corner of the cursor image where the user is actually pointing the mouse.
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  • 04 Nov 2022
Topic Review
Insulin Signaling
The insulin signaling pathway begins with the binding of the peptide hormone insulin to its corresponding receptor, the insulin receptor. The insulin receptor is a receptor tyrosine kinase (RTK) that conformationally consists of two alpha and two beta subunit tetramers. The insulin receptor exhibiting kinase activity is responsible for its autophosphorylation at the tyrosine residue site upon insulin binding.
  • 6.7K
  • 28 Sep 2021
Topic Review
Hot Dry Rock Geothermal Energy
Hot dry rock (HDR) is an extremely abundant source of geothermal energy that is difficult to access. A vast store of thermal energy is contained within hot – but essentially dry and impervious crystalline basement rocks found almost everywhere deep beneath Earth's surface. A concept for the extraction of useful amounts of geothermal energy from HDR originated at the Los Alamos National Laboratory in 1970, and Laboratory researchers were awarded a U.S. patent covering it. This technology has been tested extensively with multiple deep wells drilled in several field areas around world including the USA, Japan, Australia, France, and the UK and investment of billions of research funds. It continues to be the focus along with a related technique called EGS for sizable government-led research studies involving costly deep drilling and rock studies. Thermal energy has been recovered in reasonably sustainable tests over periods of years and in some cases electrical power generation was also achieved. However no commercial projects are ongoing or likely due to the high cost and limited capacity of the engineered reservoirs, associated wells, and pumping systems. Commonly tests have opened just one or more fractures such that the reservoir surface heat exchange areas are limited. For this technology to successfully compete with other energy sources, drilling costs would have to drop drastically or new approaches that result in much more extensive, complex, and higher rate flow paths through actual fracture networks would have to be established. The enthusiasim evident here on Wikipedia and in the research community is justified by the vast extent of the energy supply and the low environmental impact of the method however significant breakthroughs will be required to make this a commercial energy resource.
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  • 30 Oct 2022
Topic Review
Marriageable Age
Marriageable age (or marriage age) is the minimum age at which a person is allowed by law to marry, either as a right or subject to parental, judicial or other forms of approval. Age and other prerequisites to marriage vary between jurisdictions, but in the vast majority of jurisdictions, the marriage age as a right is set at the age of majority. Nevertheless, most jurisdictions allow marriage at a younger age with parental or judicial approval, and some also allow younger people to marry if the female is pregnant. Until recently, the marriageable age for girls was lower in many jurisdictions than for boys, on the premise that girls mature at an earlier age than boys. This law has been viewed to be discriminatory, so that in many countries the marriageable age of girls has been raised to equal that of boys. That age is most commonly 18, but there are variations, some higher and some lower. The marriageable age should not be confused with the age of maturity or the age of consent, though, they may be the same in many places. In many developing countries, the official age prescriptions stand as mere guidelines. International organizations, such as UNICEF, regard a marriage by a person below the age of 18 as a child marriage and a violation of human rights. The 55 parties to the 1962 Convention on Consent to Marriage, Minimum Age for Marriage, and Registration of Marriages have agreed to specify a minimum marriage age by statute law‚ to override customary, religious, and tribal laws and traditions. When the marriageable age under a law of a religious community is lower than that under the law of the land, the state law prevails. However, some religious communities do not accept the supremacy of state law in this respect, which may lead to child marriage or forced marriage. The 123 parties to the 1956 Supplementary Convention on the Abolition of Slavery have agreed to adopt a prescribed “suitable” minimum age for marriage.
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  • 21 Nov 2022
Topic Review
Mitsubishi Challenger
The Mitsubishi Challenger is a mid-size SUV produced by the Japanese manufacturer Mitsubishi Motors since 1996, spanning over three generations. Since 2015, for the third generation model, Mitsubishi has no longer used the Challenger name, but using the Pajero Sport/Montero Sport/Shogun Sport name instead.
  • 6.7K
  • 10 Oct 2022
Topic Review
Parental Involvement
Parental involvement is seen as an important strategy for the advancement of the quality of education. The ultimate objective of this is to expand the academic and social capacities of students, especially those of disadvantaged backgrounds determined by ethnic minority origin and low socio-economic status. In this contribution, various forms of both parental and school-initiated involvement will be described. In addition, results of studies into the effectiveness of parental involvement will be presented.
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  • 15 Nov 2021
Topic Review
Agorism
Agorism is a libertarian social philosophy that advocates creating a society in which all relations between people are voluntary exchanges by means of counter-economics, thus engaging with aspects of peaceful revolution. It was first proposed by libertarian philosopher Samuel Edward Konkin III at two conferences, CounterCon I in October 1974 and CounterCon II in May 1975, both conferences organized by J. Neil Schulman.
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  • 23 Nov 2022
Topic Review
State Within a State
A state within a state or a deep state is a political situation in a country when an internal organ, such as the armed forces or public authorities (intelligence agencies, police, secret police, administrative agencies, and branches of government bureaucracy), does not respond to the civilian political leadership. Although the state within a state can be conspiratorial in nature, the deep state can also take the form of entrenched unelected career civil servants acting in a non-conspiratorial manner, to further their own interests (e.g. continuity of the state as distinct from the administration, job security, enhanced power and authority, pursuit of ideological goals and objectives, and the general growth of their agency) and in opposition to the policies of elected officials, by obstructing, resisting, and subverting the policies, conditions and directives of elected officials. The term, like many in politics, derives from the Greek language (κράτος εν κράτει, kratos en kratei, later adopted into Latin as imperium in imperio or status in statu). Sometimes the term refers to state companies that, though formally under the command of the government, act 'de facto' like private corporations. Sometimes the term refers to companies that, though formally private, act de facto like "states within a state". Political debate surrounding the separation of church and state previously revolved around the perception that if left unchecked the Church might turn into a kind of State within a State, an illegitimate outgrowth of the State's natural civil power. In the field of political science, this pop culture concept is studied within the literature on the state. Current literature on the state generally traces a lineage to Bringing the State Back In (1985) and remains an active body of scholarly research to this day. Within this literature, the state is understood as both venue (a set of rules under which others act and interact) as well as actor (with its own agenda). An example of a non-conspiratorial version of the 'state as actor' from the empirical scholarly literature would be "doing truth to power" (as a play on speaking truth to power, which is what journalists often aspire to do) as studied by Todd La Porte. Under this dual understanding, the conspiratorial version of the deep state concept would be one version of the 'state as actor' while the non-conspiratorial version would be another version of the 'state as venue.' The fundamental takeaway from the scholarly literature on the dual nature of the state is that the 'state as actor' (deep state) is a characteristic of all states which can have both good and bad effects and should not be seen as bad by default.
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  • 10 Oct 2022
Topic Review
Chalk
Chalk is a soft, white, porous, sedimentary carbonate rock, a form of limestone composed of the mineral calcite. Calcite is an ionic salt called calcium carbonate or CaCO3. It forms under reasonably deep marine conditions from the gradual accumulation of minute calcite shells (coccoliths) shed from micro-organisms called coccolithophores. Flint (a type of chert) is very common as bands parallel to the bedding or as nodules embedded in chalk. It is probably derived from sponge spicules or other siliceous organisms as water is expelled upwards during compaction. Flint is often deposited around larger fossils such as Echinoidea which may be silicified (i.e. replaced molecule by molecule by flint). Chalk, as seen in Cretaceous deposits of Western Europe, is unusual among sedimentary limestones in the thickness of the beds. Most cliffs of chalk have very few obvious bedding planes unlike most thick sequences of limestone such as the Carboniferous Limestone or the Jurassic oolitic limestones. This may indicate very stable conditions over tens of millions of years. Chalk has greater resistance to weathering and slumping than the clays with which it is usually associated, thus forming tall, steep cliffs where chalk ridges meet the sea. Chalk hills, known as chalk downland, usually form where bands of chalk reach the surface at an angle, so forming a scarp slope. Because chalk is well jointed it can hold a large volume of ground water, providing a natural reservoir that releases water slowly through dry seasons.
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  • 29 Nov 2022
Topic Review
Leucaena leucocephala as Protein Source
White leadtree or Leucaena (Leucaena leucocephala) (), also known as ipil-ipil, is native to Central America and has spread and/or naturalized all over the World at a latitude between 30° N and 30° S due to a shrub variety used as a shade tree for coffee, cocoa, hemp plantations, pepper, vanilla, and other essences.
  • 6.6K
  • 04 Aug 2021
Topic Review
Segmentation
Segmentation in biology is the division of some animal and plant body plans into a series of repetitive segments. This article focuses on the segmentation of animal body plans, specifically using the examples of the taxa Arthropoda, Chordata, and Annelida. These three groups form segments by using a "growth zone" to direct and define the segments. While all three have a generally segmented body plan and use a growth zone, they use different mechanisms for generating this patterning. Even within these groups, different organisms have different mechanisms for segmenting the body. Segmentation of the body plan is important for allowing free movement and development of certain body parts. It also allows for regeneration in specific individuals.
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  • 29 Sep 2022
Topic Review
Secular Humanism
Secular humanism, often simply called humanism, is a philosophy or life stance that embraces human reason, secular ethics, and philosophical naturalism while specifically rejecting religious dogma, supernaturalism, and superstition as the basis of morality and decision making. Secular humanism posits that human beings are capable of being ethical and moral without religion or belief in a deity. It does not, however, assume that humans are either inherently good or evil, nor does it present humans as being superior to nature. Rather, the humanist life stance emphasizes the unique responsibility facing humanity and the ethical consequences of human decisions. Fundamental to the concept of secular humanism is the strongly held viewpoint that ideology—be it religious or political—must be thoroughly examined by each individual and not simply accepted or rejected on faith. Along with this, an essential part of secular humanism is a continually adapting search for truth, primarily through science and philosophy. Many secular humanists derive their moral codes from a philosophy of utilitarianism, ethical naturalism, or evolutionary ethics, and some advocate a science of morality. Humanists International is the world union of more than one hundred humanist, rationalist, irreligious, atheist, Bright, secular, Ethical Culture, and freethought organizations in more than 40 countries. The "Happy Human" is recognized as the official symbol of humanism internationally, used by secular humanist organizations in every part of the world. Those who call themselves humanists are estimated to number between four and five million people worldwide.
  • 6.6K
  • 14 Oct 2022
Topic Review
History of Geography
This article explores the history of geography.
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  • 20 Oct 2022
Topic Review
Ge'ez
Ge'ez (/ˈɡiːɛz/; ግዕዝ, Gəʿəz Template:IPA-gez; also transliterated Gi'iz) is an ancient South Semitic language of the Ethiosemitic branch. The language originates from the region encompassing northern Ethiopia and southern Eritrea in the Horn of Africa. Today, Ge'ez is used only as the main language of liturgy of the Ethiopian Orthodox Tewahedo and Eritrean Orthodox Tewahedo churches, the Ethiopian and Eritrean Catholic churches, and the Beta Israel Jewish community. However, in Ethiopia, Amharic or other local languages, and in Eritrea and Ethiopia's Tigray Region, Tigrinya may be used for sermons. Amharic, Tigrinya, and Tigre are closely related to Ge'ez. The closest living languages to Ge'ez are Tigre and Tigrinya with lexical similarity at 71% and 68%, respectively. Some linguists do not believe that Ge'ez constitutes a common ancestor of modern Ethiosemitic languages, but that Ge'ez became a separate language early on from another hypothetical unattested language, which can be seen as an extinct sister language of Amharic, Tigre and Tigrinya. The foremost Ethiopian experts such as Amsalu Aklilu point to the vast proportion of inherited nouns that are unchanged, and even spelled identically in both Ge'ez and Amharic (and to a lesser degree, Tigrinya).
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  • 17 Nov 2022
Topic Review
Preterism
Preterism, a Christian eschatological view, interprets some (partial preterism) or all (full preterism) prophecies of the Bible as events which have already happened. This school of thought interprets the Book of Daniel as referring to events that happened from the 7th century BC until the first century AD, while seeing the prophecies of the Book of Revelation as events that happened in the first century AD. Preterism holds that Ancient Israel finds its continuation or fulfillment in the Christian church at the destruction of Jerusalem in AD 70. The term preterism comes from the Latin praeter, which is a prefix denoting that something is "past" or "beyond". Adherents of preterism are known as preterists. Preterism teaches that either all (full preterism) or a majority (partial preterism) of the Olivet discourse had come to pass by AD 70. Historically, preterists and non-preterists have generally agreed that the Jesuit Luis de Alcasar (1554–1613) wrote the first systematic preterist exposition of prophecy Vestigatio arcani sensus in Apocalypsi (published in 1614) during the Counter-Reformation.
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  • 11 Oct 2022
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