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HandWiki. Brilliant Blue FCF. Encyclopedia. Available online: https://encyclopedia.pub/entry/35057 (accessed on 23 September 2026).
HandWiki. Brilliant Blue FCF. Encyclopedia. Available at: https://encyclopedia.pub/entry/35057. Accessed September 23, 2026.
HandWiki. "Brilliant Blue FCF" Encyclopedia, https://encyclopedia.pub/entry/35057 (accessed September 23, 2026).
HandWiki. (2022, November 17). Brilliant Blue FCF. In Encyclopedia. https://encyclopedia.pub/entry/35057
HandWiki. "Brilliant Blue FCF." Encyclopedia. Web. 17 November, 2022.
Brilliant Blue FCF
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The content is sourced from: https://handwiki.org/wiki/Chemistry:Brilliant_Blue_FCF

Brilliant Blue FCF (Blue 1) is a synthetic organic compound used primarily as a blue colorant for processed foods, medications, dietary supplements, and cosmetics. It is classified as a triarylmethane dye and is known under various names, such as FD&C Blue No. 1 or Acid Blue 9. It is denoted by E number E133 and has a color index of 42090. It has the appearance of a blue powder and is soluble in water and glycerol, with a maximum absorption at about 628 nanometers. It is one of the oldest FDA-approved color additives and is generally considered nontoxic and safe.

glycerol triarylmethane color

References

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  2. Gessner, Thomas; Mayer, Udo (2002). "Triarylmethane and Diarylmethane Dyes". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a27_179. ISBN 3527306730.  https://dx.doi.org/10.1002%2F14356007.a27_179
  3. Newsome, Andrew G.; Culver, Catherine A.; van Breemen, Richard B. (2014-07-16). "Nature's Palette: The Search for Natural Blue Colorants". Journal of Agricultural and Food Chemistry 62 (28): 6498–6511. doi:10.1021/jf501419q. ISSN 0021-8561. PMID 24930897.  https://dx.doi.org/10.1021%2Fjf501419q
  4. Nutrition, Center for Food Safety and Applied (2019-04-14). "Overview of Food Ingredients, Additives & Colors" (in en). FDA. https://www.fda.gov/food/food-ingredients-packaging/overview-food-ingredients-additives-colors. 
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  8. "Quantifying preferential flow in soils: A review of different techniques". Journal of Hydrology 378 (1): 179–204. 2009-11-15. doi:10.1016/j.jhydrol.2009.08.013. Bibcode: 2009JHyd..378..179A.  https://dx.doi.org/10.1016%2Fj.jhydrol.2009.08.013
  9. "Variations on the "Blue-Bottle" Demonstration Using Food Items That Contain FD&C Blue #1". Journal of Chemical Education 92 (10): 1684–1686. 2015-10-13. doi:10.1021/acs.jchemed.5b00190. Bibcode: 2015JChEd..92.1684S.  https://dx.doi.org/10.1021%2Facs.jchemed.5b00190
  10. "Absorption of triphenylmethane dyes Brilliant Blue and Patent Blue through intact skin, shaven skin and lingual mucosa from daily life products". Food and Chemical Toxicology 52: 19–27. February 2013. doi:10.1016/j.fct.2012.10.027. PMID 23127598. "porcine tongue dorsum was exposed to human saliva with 15,000 ng/cm2 of dye for 20 min. 24-h diffusion resulted in 34 ng/cm2 of BB and 86 ng/cm2 of PB which can be directly absorbed into the blood system.".  https://dx.doi.org/10.1016%2Fj.fct.2012.10.027
  11. "An innovative brilliant blue FCF method for fluorescent staining of fungi and bacteria". Biotechnic & Histochemistry 86 (4): 280–7. August 2011. doi:10.3109/10520295.2010.492733. PMID 20560873.  https://dx.doi.org/10.3109%2F10520295.2010.492733
  12. "Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)" (in en). Medical Devices: Evidence and Research 9: 1–10. 2015-12-22. doi:10.2147/mder.s90591. PMID 26730213.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4694675
  13. "Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics". The Journal of Allergy and Clinical Immunology 64 (1): 32–7. July 1979. doi:10.1016/0091-6749(79)90080-0. PMID 447949. https://www.jacionline.org/article/0091-6749(79)90080-0/pdf. 
  14. "FD&C Blue No. 1.". Drugs.com. https://www.drugs.com/inactive/fd-c-blue-no-1-244.html. 
  15. "E133". zusatzstoffe-online.de. http://www.zusatzstoffe-online.de/zusatzstoffe/20.e133_brillantblau_fcf.html. 
  16. "Brilliant Blue Dyes in Daily Food: How Could Purinergic System Be Affected?". International Journal of Food Science 2016: 7548498. 2016. doi:10.1155/2016/7548498. PMID 27833914.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5090090
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  18. "Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation". Journal of Visualized Experiments (122). April 2017. doi:10.3791/55525. PMID 28448011.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5564473
  19. "Use of Brilliant Blue FCF during vein graft preparation inhibits intimal hyperplasia". Journal of Vascular Surgery 64 (2): 471–478. August 2016. doi:10.1016/j.jvs.2015.02.028. PMID 27763268.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5480606
  20. Voskresensky, Igor V.; Wise, Eric S.; Hocking, Kyle M.; Li, Fan Dong; Osgood, Michael J.; Komalavilas, Padmini; Brophy, Colleen; Cheung-Flynn, Joyce (2014-11-01). "Brilliant Blue FCF as an Alternative Dye for Saphenous Vein Graft Marking: Effect on Conduit Function". JAMA Surgery 149 (11): 1176–81. doi:10.1001/jamasurg.2014.2029. ISSN 2168-6254. PMID 25251505.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4237645
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