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Topic Review
Froth Washing in Flotation
Froth flotation is a mineral processing technique that is popular when processing low-grade ores. It involves introducing chemically treated, finely ground ore in the form of a slurry into a flotation cell where the air is also added in the form of bubbles. The cell is agitated resulting in the air bubbles rising to the top and creating a froth, as bubbles rise, hydrophilic particles attach to the rising bubbles creating a froth which is collected in the weir or using launders for further treatment. The froth is washed using various froth-washing techniques to reduce entrainment and improve the grade of the froth. Froth washing can be achieved using froth washing jets or froth washing trays, this can be achieved internally/externally with regards to the position in the froth layer.
  • 3.0K
  • 30 Nov 2022
Topic Review
L-Asparaginase
l-Asparaginase (ASNase, EC 3.5.1.1) is a tetrameric aminohydrolase enzyme that catalyses the hydrolysis of the amino acid L-Asparagine into ammonia and L-aspartic acid. ASNase is present in different organisms such as bacteria, fungi, plant tissues and algae. ASNase is used in the pharmaceutical field as an anticancer drug for the treatment of acute lymphoblastic leukemia (ALL) and other malignant diseases such as Hodgkin’s disease. In the food sector, ASNase is used to prevent the formation of acrylamide, a toxic compound formed when starch-rich foods are cooked at temperatures above 100 °C. ASNase can also be used as a biosensor for the detection of L-asparagine levels.
  • 3.0K
  • 21 Feb 2021
Topic Review
Detecting Lithium Mineralizations from Space
Optical and thermal remote sensing data have been an important tool in geological exploration for certain deposit types. However, the present economic and technological advances demand the adaptation of the remote sensing data and image processing techniques to the exploration of other raw materials like lithium (Li). A review of the application studies and developments in this field was also made. The addressed topics include: (i) achievements made in Li exploration using remote sensing methods; (ii) the main weaknesses of the approaches; (iii) how to overcome these difficulties; and (iv) the expected research perspectives. We expect that the number of studies concerning this topic will increase in the near future and that remote sensing will become an integrated and fundamental tool in Li exploration.
  • 3.0K
  • 30 Oct 2020
Topic Review
Emerging Thermo-Mechanical Energy Storage Technologies
Thermo-mechanical energy storage can be a cost-effective solution to provide flexibility and balance highly renewable energy systems. Thermo-Mechanical Energy Storage (TMES) can be directly compared with pumped hydro storage because they have similar discharge characteristics and capacity (order of 100 s of MW).
  • 3.0K
  • 13 Sep 2022
Topic Review
Thread Block
A thread block is a programming abstraction that represents a group of threads that can be executed serially or in parallel. For better process and data mapping, threads are grouped into thread blocks. The number of threads varies with available shared memory. 'The number of threads in a thread block is also limited by the architecture to a total of 512 threads per block.' The threads in the same thread block run on the same stream processor. Threads in the same block can communicate with each other via shared memory, barrier synchronization or other synchronization primitives such as atomic operations. Multiple blocks are combined to form a grid. All the blocks in the same grid contain the same number of threads. Since the number of threads in a block is limited to 512, grids can be used for computations that require a large number of thread blocks to operate in parallel. CUDA is a parallel computing platform and programming model that higher level languages can use to exploit parallelism. In CUDA, the kernel is executed with the aid of threads. The thread is an abstract entity that represents the execution of the kernel. A kernel is a small program or a function. Multi threaded applications use many such threads that are running at the same time, to organize parallel computation. Every thread has an index, which is used for calculating memory address locations and also for taking control decisions.
  • 3.0K
  • 29 Nov 2022
Topic Review
Myeloid-Derived Suppressor Cells in Cancer
The emergence of immunotherapy has been an astounding breakthrough in cancer treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have shown remarkable therapeutic outcomes. However, response rates from immunotherapy have been reported to be varied, with some having pronounced success and others with minimal to no clinical benefit. An important aspect associated with this discrepancy in patient response is the immune-suppressive effects elicited by the tumour microenvironment (TME). Immune suppression plays a pivotal role in regulating cancer progression, metastasis, and reducing immunotherapy success. Most notably, myeloid-derived suppressor cells (MDSC), a heterogeneous population of immature myeloid cells, have potent mechanisms to inhibit T-cell and NK-cell activity to promote tumour growth, development of the pre-metastatic niche, and contribute to resistance to immunotherapy. Accumulating research indicates that MDSC can be a therapeutic target to alleviate their pro-tumourigenic functions and immunosuppressive activities to bolster the efficacy of checkpoint inhibitors.
  • 3.0K
  • 25 May 2021
Topic Review
Associations between Population Density and Health Outcomes
Both density of population and proximity to man-made activities, as well as the natural environment, concentrate risk for humans. Population density is therefore a measure of “the degree of pressure on natural resources” as well as an indicator reflecting the level of human activity within a specific bounded landscape. Exposure to contaminants from soil, water or air coupled with social or economic vulnerability and population density may increase potential harm to health at a subclinical or clinical level.
  • 3.0K
  • 14 Mar 2022
Topic Review
Knowledge Graph
The Google Knowledge Graph is a knowledge base used by Google and its services to enhance its search engine's results with information gathered from a variety of sources. The information is presented to users in an infobox next to the search results. Knowledge Graph infoboxes were added to Google's search engine in May 2012, starting in the United States, with international expansion by the end of the year. The information covered by Google's Knowledge Graph grew quickly after launch, tripling its size within seven months (covering 570 million entities and 18 billion facts) and answering "roughly one-third" of the 100 billion monthly searches Google processed in May 2016. It has been criticized for providing answers without source attribution or citation. Information from the Knowledge Graph is presented as a box, which Google has referred to as the "knowledge panel", to the right (top on mobile) of search results. According to Google, this information is retrieved from many sources, including the CIA World Factbook, Wikidata, and Wikipedia. In October 2016, Google announced that the Knowledge Graph held over 70 billion facts; by May 2020, this had grown to 500 billion facts on 5 billion entities. There is no official documentation of how the Knowledge Graph is implemented. It is used to answer direct spoken questions in Google Assistant and Google Home voice queries.
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  • 02 Dec 2022
Topic Review
Tannylated Calcium Carbonate Materials
Calcium carbonate (CaCO3)-based materials have received notable attention for biomedical applications owing to their safety and beneficial characteristics, such as pH sensitivity, carbon dioxide (CO2) gas generation, and antacid properties. Herein, to additionally incorporate antioxidant and anti-inflammatory functions, we prepared tannylated CaCO3 (TA-CaCO3) materials using a simple reaction between tannic acid (TA), calcium (Ca2+), and carbonate (CO32−) ions. TA-CaCO3 synthesized at a molar ratio of 1:75 (TA:calcium chloride (CaCl2)/sodium carbonate (Na2CO3)) showed 3–6 μm particles, comprising small nanoparticles in a size range of 17–41 nm. The TA-CaCO3 materials could efficiently neutralize the acid solution and scavenge free radicals. 
  • 3.0K
  • 12 May 2021
Topic Review
Aqueous Soluble Drug
The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with low solubility convey a higher risk of failure for drug innovation and development. Pharmacokinetics, pharmacodynamics, and several other parameters, such as drug distribution, protein binding and absorption, are majorly affected by their solubility.
  • 3.0K
  • 20 Sep 2022
Topic Review
Heat Recovery from Wastewater
Wastewater from domestic, industrial and commercial developments maintains considerable amounts of thermal energy after discharging into the sewer system. 
  • 3.0K
  • 29 Jun 2021
Topic Review
Innovations and Emerging Cooling Technologies for Greenhouses
The climate control inside the greenhouse constitutes an efficient methodology for maintaining a satisfactory environment that fulfills the requirements of high-yield crops and reduced energy and water resource consumption. In hot climates, the cooling systems, which are assisted by an effective control technique, constitute a suitable path for maintaining an appropriate climate inside the greenhouse, where the required temperature and humidity distribution is maintained.
  • 3.0K
  • 11 Mar 2022
Topic Review
Balloon (Aeronautics)
In aeronautics, a balloon is an unpowered aerostat, which remains aloft or floats due to its buoyancy. A balloon may be free, moving with the wind, or tethered to a fixed point. It is distinct from an airship, which is a powered aerostat that can propel itself through the air in a controlled manner. Many balloons have a basket, gondola, or capsule suspended beneath the main envelope for carrying people or equipment (including cameras and telescopes, and flight-control mechanisms).
  • 3.0K
  • 27 Oct 2022
Topic Review
Absenteeism
Absenteeism is a habitual pattern of absence from a duty or obligation without good reason. Generally, absenteeism is unplanned absences. Absenteeism has been viewed as an indicator of poor individual performance, as well as a breach of an implicit contract between employee and employer. It is seen as a management problem, and framed in economic or quasi-economic terms. More recent scholarship seeks to understand absenteeism as an indicator of psychological, medical, or social adjustment to work.
  • 3.0K
  • 23 Nov 2022
Topic Review Peer Reviewed
Need for Widely Applicable Cultural Competencies in the Healthcare of Humans and Animals
This entry discusses the importance of cultural competence in the healthcare of humans and animals, its challenges, its mixed research results, and the need for widely applicable competencies. Although there is research evidence showing that cultural competence is linked with patient satisfaction, better doctor–patient relationships, adherence to therapy, and to some extent, better health outcomes, there is a huge variety of models and competencies in the literature, which has sometimes resulted in inclusive outcomes, confusion as to what constitutes the necessary competencies, and patchy implementation. In spite of the development of cultural competence in human healthcare, its implementation in veterinary medicine remains poor. On this note, the aims of this entry are to provide a brief overview of the cultural competence in healthcare and veterinary medicine and education, to outline the important facts, and to highlight the need for more standardisation in implementing and testing widely applicable cultural competencies for both human and veterinary healthcare.
  • 3.0K
  • 07 Aug 2023
Topic Review
Pathophysiology of the Metabolic Syndrome
Metabolic syndrome (MetS) is a disease that has a complex etiology. It is defined as the co-occurrence of several pathophysiological disorders, including obesity, hyperglycemia, hypertension, and dyslipidemia.
  • 3.0K
  • 22 Apr 2022
Topic Review
Blue Gene
Blue Gene is an IBM project aimed at designing supercomputers that can reach operating speeds in the PFLOPS (petaFLOPS) range, with low power consumption. The project created three generations of supercomputers, Blue Gene/L, Blue Gene/P, and Blue Gene/Q. Blue Gene systems have often led the TOP500 and Green500 rankings of the most powerful and most power efficient supercomputers, respectively. Blue Gene systems have also consistently scored top positions in the Graph500 list. The project was awarded the 2009 National Medal of Technology and Innovation. As of 2015, IBM seems to have ended the development of the Blue Gene family though no public announcement has been made. IBM's continuing efforts of the supercomputer scene seems to be concentrated around OpenPower, using accelerators such as FPGAs and GPUs to battle the end of Moore's law.
  • 3.0K
  • 29 Sep 2022
Topic Review
2017 Catalan Independence Referendum
The Catalan independence referendum of 2017, also known by the numeronym 1-O (for "1 October") in Spanish media, was an independence referendum held on 1 October 2017 in the Spanish autonomous community of Catalonia, passed by the Parliament of Catalonia as the Law on the Referendum on Self-determination of Catalonia and called by the Generalitat de Catalunya. It was declared unconstitutional on 7 September 2017 and suspended by the Constitutional Court of Spain after a request from the Spanish government, who declared it a breach of the Spanish Constitution. Additionally, in early September the High Court of Justice of Catalonia had issued orders to the police to try to prevent it, including the detention of various persons responsible for its preparation. Due to alleged irregularities during the voting process as well as to the use of force by the National Police Corps and Civil Guard, international observers invited by the Generalitat declared that the referendum failed to meet the minimum international standards for elections. The referendum was approved by the Catalan parliament in a session in which only nationalist parliamentarians participated on 6 September 2017 along with the Law of juridical transition and foundation of the Republic of Catalonia the following day 7 September, which stated that independence would be binding with a simple majority, without requiring a minimum turnout. After being suspended, the law was finally declared void on 17 October, being also unconstitutional according to the Statute of Autonomy of Catalonia which requires a two-thirds majority, 90 seats, in the Catalan parliament for any change to Catalonia's status. The referendum question, which voters answered with "Yes" or "No", was "Do you want Catalonia to become an independent state in the form of a republic?". The "Yes" side won, with 2,044,038 (92.01%) voting for independence and 177,547 (7.99%) voting against, on a turnout of 43.03%. The Catalan government estimated that up to 770,000 votes were not cast due to polling stations being closed off during the police crackdown, although the "universal census" system introduced earlier in the day allowed electors to vote at any given polling station. Catalan government officials have argued that the turnout would have been higher were it not for Spanish and Catalan police suppression of the vote. On the other hand, most voters who did not support Catalan independence did not turn out, as the constitutional political parties asked citizens not to participate in what they considered an illegal referendum. Additionally, numerous cases of voters casting their votes several times or with lack of identification were reported, and the counting process and the revision of the census were not performed with quality standards ensuring impartiality. In the days leading to the referendum, the High Court of Justice of Catalonia ordered police forces to impede the use of public premises for the imminent voting. However, on the day of the referendum, the inaction of part of the autonomous police force of Catalonia, the Mossos d'Esquadra, allowed many polling stations to open. The National Police Corps and the Guardia Civil intervened and raided several polling stations after they opened. 893 civilians and 111 agents of the National Police and the Guardia Civil were reported to have been injured. According to various sources these previously reported figures may have been exaggerated. According to the judge from Barcelona who is currently investigating the accusations of police violence, there were 218 persons injured on that day in the city of Barcelona alone, 20 of whom were agents. According to the official final report by the Catalan Health Service (CatSalut) of the Generalitat 1066 civilians, 11 agents of the National Police and the Guardia Civil and 1 agent of the regional police, the Mossos d'Esquadra, were injured. The United Nations High Commissioner for Human Rights, Zeid Ra'ad Al Hussein, urged the Spanish government to prove all acts of violence that took place to prevent the referendum. The police action also received criticism from Amnesty International and Human Rights Watch which defined it as an "excessive and unnecessary use of force". Spanish Supreme Court judge Pablo Llarena stated Puigdemont ignored the repeated warnings he received about the escalation of violence if the referendum was held. Mossos d'Esquadra are being investigated for disobedience, for allegedly not having complied with the orders of the High Court of Justice of Catalonia. Including Josep Lluís Trapero Álvarez, the Mossos d'Esquadra major, who is being investigated for sedition by the Spanish National Court. Mossos d'Esquadra deny those accusations and allege they obeyed the orders but applied the principle of proportionality, which is required by Spanish law in all police operations.
  • 3.0K
  • 07 Nov 2022
Topic Review
Agricultural Electrostatic Spraying
Agricultural electrostatic spraying technology is superior to non-electrostatic spraying technology. Electrostatic droplets have better “adhesion, penetration, and encircling ability” in crops. Electrostatic spraying technology is used to charge droplets to induce an electric field on the surface of the crop leaves, thus adsorbing electrostatic droplets and achieving directional movement of the charged droplets.
  • 3.0K
  • 03 Dec 2021
Topic Review
Bacterial Biofilm Formation and Pathogenesis
Biofilm formation is an integral part of the microbial life cycle in nature. In food processing environments, bacterial transmissions occur primarily through raw or undercooked foods and by cross-contamination during unsanitary food preparation practices. Foodborne pathogens form biofilms as a survival strategy in various unfavorable environments, which also become a frequent source of recurrent contamination and outbreaks of foodborne illness.
  • 3.0K
  • 23 Sep 2021
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