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Topic Review
Hydrogels Classification
Hydrogels are attractive biomaterials with favorable characteristics due to their water uptake capacity. However, hydrogel properties are determined by the cross-linking degree and nature, the tacticity, and the crystallinity of the polymer. 
  • 2.3K
  • 08 Dec 2021
Topic Review
Plant Extract-Mediated Synthesis and Characterization of Nanoparticles
Eucalyptus globulus (EG) is an endemic plant in Australia that is widely found throughout the world. It is the main source of botanical essential oils and is well-recognized in pharmacopeia around the globe. In the plant-assisted fabrication of nanoparticles, the salt solution and extract are simply mixed at room temperature or slightly high temperature, resulting in the synthesis of nanoparticles (NPs) within minutes.
  • 2.3K
  • 13 Jul 2023
Topic Review
Applications of Ellagic Acid and Its Derivatives
Ellagitannins (ETs), characterized by their diversity and chemical complexity, belong to the class of hydrolysable tannins that, via hydrolysis under acidic or alkaline conditions, can yield ellagic acid (EA). They are mostly found as a part of extractives in angiosperms. As known antioxidants and chelators, EA and EA derivatives are drawing an increasing interest towards extensive technical and biomedical applications. 
  • 2.3K
  • 29 Mar 2022
Topic Review
Subcritical-Water Extraction of Natural Products
Subcritical water refers to high-temperature and high-pressure water, but below water's critical point of 374 °C and 218 atm. A unique and useful characteristic of subcritical water is that its polarity can be dramatically decreased with increasing temperature. Therefore, subcritical water can behave similarly to methanol or ethanol. This makes subcritical water a green extraction fluid used for a variety of organic species. 
  • 2.2K
  • 09 Jul 2021
Topic Review
Shugoshin
Shugoshin (meaning “guardian spirit” in Japanese) is a homo-dimeric phospho-protein belonging to the shugoshin protein family. Shugoshin is conserved from single-celled yeast to multicellular mammals including humans. Shugoshin shares several structural features with other members of the shugoshin family, including a basic region at the C-terminus that is essential for centromere binding, chromosome localization, and an N-terminal coiled-coil domain that may regulate its dimerization and interaction with other proteins.
  • 2.2K
  • 27 Jul 2021
Topic Review
DMF as CO Surrogate in Carbonylation Reactions
Transition metal-catalyzed carbonylation reactions have emerged as one of the most relevant synthetic approaches for the preparation of carbonyl-containing molecules. The most commonly used protocol for the insertion of a carbonyl moiety is the use of carbon monoxide (CO) but, due to its toxic and explosive nature, this process is not suitable at an industrial scale. The chemistry of CO surrogates has received large attention as a way to use less expensive and more environmentally friendly methods. Among the various CO surrogates, N,N-dimethylformamide (DMF) has been paid greater attention due to its low cost and easy availability.
  • 2.1K
  • 21 Dec 2021
Topic Review
Natural and Synthetic Halogenated Amino Acids
The 3D structure and surface characteristics of proteins and peptides are crucial for interactions with receptors or ligands and can be modified to some extent to modulate their biological roles and pharmacological activities. The introduction of halogen atoms on the side-chains of amino acids is a powerful tool for effecting this type of tuning, influencing both the physico-chemical and structural properties of the modified polypeptides, helping to first dissect and then rationally modify features that affect their mode of action.
  • 2.1K
  • 16 Dec 2021
Topic Review
Structure of Humic Substances
Humic substances (HS) are dominant components of soil organic matter and are recognized as natural, effective growth promoters to be used in sustainable agriculture. In recent years, many efforts have been made to get insights on the relationship between HS chemical structure and their biological activity in plants using combinatory approaches. Relevant results highlight the existence of key functional groups in HS that might trigger positive local and systemic physiological responses via a complex network of hormone-like signaling pathways. The biological activity of HS finely relies on their dosage, origin, molecular size, degree of hydrophobicity and aromaticity, and spatial distribution of hydrophilic and hydrophobic domains. The molecular size of HS also impacts their mode of action in plants, as low molecular size HS can enter the root cells and directly elicit intracellular signals, while high molecular size HS bind to external cell receptors to induce molecular responses. Main targets of HS in plants are nutrient transporters, plasma membrane H+-ATPases, hormone routes, genes/enzymes involved in nitrogen assimilation, cell division, and development. 
  • 2.1K
  • 08 May 2021
Topic Review
Hyaluronic Acid Hydrogels
Hyaluronic acid (HA) hydrogels display a wide variety of biomedical applications ranging from tissue engineering to drug vehiculization and controlled release. This entry compiles the currently used approaches for the development of hyaluronic acid hydrogels under physiological/mild conditions.
  • 2.1K
  • 15 Sep 2021
Topic Review
Biological Properties of Anthocyanin Pigments in Blood Oranges
Anthocyanins are natural pigments that give a red, purple, and blue color to many plant, flower, fruit, and vegetable species. Their presence within the genus Citrus was first reported in 1916, and it is well-known that the red color of the flesh and rind of blood (red or pigmented) oranges (Citrus sinensis L. Osbeck) is due to the presence of anthocyanins. They are also present in the young shoots, flowers, and peel of lemon (Citrus limon (L.) Burm. f.), citron (Citrus medica L.), and other citrus species. 
  • 2.1K
  • 22 Dec 2022
Topic Review
Modified Nb-Si-Based Multi-Element Alloys
Nb-Si-based superalloys are considered as the most promising high-temperature structural material to replace the Ni-based superalloys. Unfortunately, the poor oxidation resistance is still a major obstacle to the application of Nb-Si-based alloys. Alloying is a promising method to overcome this problem.
  • 2.1K
  • 22 Nov 2021
Topic Review
Amazonian Bacuri (Platonia insignis Mart.)
Bacuri (Platonia insignis Mart) is a species from the Clusiaceae genus. Its fruit pulp is commonly used in South America in several food products, such as beverages, ice cream and candies. Only the pulp of the fruit is used, and the peels and seeds are considered waste from these industries.
  • 2.0K
  • 29 Mar 2022
Topic Review
Environmental Impact and Sustainability of Calcium Aluminate Cements
This investigation presents a critical analysis of calcium aluminate cements (CAC), specifically associated with sustainability and environmental impact, and the potential of these cements to help solve certain worldwide problems. Areas of research include cements as recycling holding materials, sustainability, circular economy, production costs, and energy. Here summarizes the current trends, perspectives, and the main concerns regarding CAC. Detailed information about the materials and processes involved in CAC is also presented. First, a general search was made using the Carrot2 Workbench metasearch engine to identify possible thematic groups correlated with CAC, then a more in-depth and specialized search was done using the Scopus database.
  • 2.0K
  • 22 Mar 2022
Topic Review
Tetrazine-Based Fluorogenic Probes
Various bioorthogonal chemistries have been used for fluorescent imaging owing to the advantageous reactions they employ. Recent advances in bioorthogonal chemistry have revolutionized labeling strategies for fluorescence imaging, with inverse electron demand Diels–Alder (iEDDA) reactions in particular attracting recent attention owing to their fast kinetics and excellent specificity. One of the most interesting features of the iEDDA labeling strategy is that tetrazine-functionalized dyes are known to act as fluorogenic probes.
  • 2.0K
  • 13 Apr 2021
Topic Review
Perspective for High-Value C2 Chemicals
The oxidative coupling of methane (OCM) to C2 hydrocarbons (C2H4 and C2H6) has aroused worldwide interest over the past decade due to the rise of vast new shale gas resources. However, obtaining higher C2 selectivity can be very challenging in a typical OCM process in the presence of easily oxidized products such as C2H4 and C2H6. Regarding this, different types of catalysts have been studied to achieve desirable C2 yields.
  • 2.0K
  • 29 Nov 2021
Topic Review
Sorbent-Based Microextraction of Natural Toxins from Food Samples
Natural toxins are chemical substances that are not toxic to the organisms that produce them, but which can be a potential risk to human health when ingested through food. Thus, it is of high interest to develop advanced analytical methodologies to control the occurrence of these compounds in food products. Current trends in sample preparation involve moving towards “greener” approaches by scaling down analytical operations, miniaturizing the instruments and integrating new advanced materials as sorbents. The combination of these new materials with sorbent-based microextraction technologies enables the development of high-throughput sample preparation methods, which improve conventional extraction and clean-up procedures.
  • 2.0K
  • 05 Nov 2021
Topic Review
Bioremediation of Heavy Metals by the Genus Bacillus
Bioremediation agents include bacteria of the genus Bacillus, among others. The best-described species in terms of the bioremediation potential of Bacillus spp. Are B. subtilis, B. cereus, or B. thuringiensis. This bacterial genus has several bioremediation strategies, including biosorption, extracellular polymeric substance (EPS)-mediated biosorption, bioaccumulation, or bioprecipitation. Due to the above-mentioned strategies, Bacillus spp. strains can reduce the amounts of metals such as lead, cadmium, mercury, chromium, arsenic or nickel in the environment. 
  • 2.0K
  • 27 Sep 2023
Topic Review
Synthesis of Quantum Dots, Polymer, and Nanocomposites
Owing to the nanometer size range, Quantum Dots (QDs) have exhibited unique physical and chemical properties which are favourable for different applications. Especially, due to their quantum confinement effect, excellent optoelectronic characteristics is been observed. This considerable progress has not only uplifted the singular usage of QDs, but also encouraged to prepare various hybrid materials to achieve superior efficiency by eliminating certain shortcomings. Such issues can be overcome by compositing QDs with polymers. 
  • 2.0K
  • 14 Apr 2022
Topic Review
Shade Covers in Water Reservoirs
Shade objects are small plastic spheres, squares or even hexagons floating on top of a water reserve for environmental reasons. The creator of shade balls in California originally used them to prevent chemical treatments in the reservoir from reacting with sunlight creating bromate, which is a carcinogen regulated by many institutions worldwide (chlorine plus sunlight turns bromine into bromate that is a potentially cancer-causing agent; because shady objects stop bromate from forming below, less chlorine is required to treat the water than without them). More recently, other environmental issues have been associated to the use of shade objects: slowing down water evaporation, preventing algae blooms, avoiding birds landing on bodies of water and promote water heating.
  • 1.9K
  • 21 Oct 2021
Topic Review
Nanomaterial-Based Biosensors for N-Terminal Pro-B-Type Natriuretic Peptide Detection
N-terminal pro-B-type natriuretic peptide (NT-proBNP), a prominent cardiac biomarker, has gained significant recognition for its role in the diagnosis and prognosis of heart failure (HF). This biomarker is synthesized as a response to ventricular volume expansion and pressure overload, conditions often indicative of cardiac stress and dysfunction. The detection of NT-ProBNP, a crucial biomarker for cardiovascular diseases, has been significantly enhanced by the integration of nanomaterials into biosensor designs. These advancements leverage the unique properties of nanomaterials to achieve high sensitivity and specificity in NT-ProBNP detection. 
  • 1.9K
  • 29 Jan 2024
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