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Biography
Benjamin Hick
Benjamin Hick (1 August 1790 – 9 September 1842) was a successful English civil and mechanical engineer, art collector and patron;[1] his improvements to the steam engine and invention of scientific tools were held in high esteem by the engineering profession,[2] some of Hick's improvements became public property without claiming the patent rights he was entitled to.[3] He was born at Hudder
  • 3.1K
  • 28 Nov 2022
Topic Review
The Factors Impacting Commuting Time
Commuting time holds a significant role in people’s daily routines, representing the duration spent traveling between home and work in the context of daily time use. In the context of rapid urbanization in developing countries, commuting time is increasing. However, excessive commuting time can have significant economic, social, and environmental consequences. For example, longer commuting time hampers per capita income growth and reduces productivity. It also impedes social interactions among residents, leading to a decline in social and economic vitality. Moreover, commuting accounts for a large proportion of urban transportation demand and is closely linked to urban carbon emissions. Additionally, it has detrimental effects on both physical and mental health, as well as the well-being of individuals. Therefore, it is crucial to investigate the factors that influence commuting time in order to mitigate its continual increase.
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  • 29 Aug 2023
Topic Review
Nepalese Army On Buffer Zone
Recent years have seen various advancements in exploration and the progress of arm forces throughout the world. Nepal is in the buffer zone. The people of Nepal sometimes face unhealthy pressure from India and sometimes from China. Indeed, the founding father of modern Nepal, King Prithvi Narayan Shah's dictum, "Nepal as a yam between two boulders". The people of the Northern part of Nepal are somehow similar cultures with Tibet(China) and they need to adjust with the people of Tibet. Similarly, east, west, and south parts of Nepal has somehow similar culture with India and they need to adjust with the people of India. This article reviews top-cited recent literature and made a compact analytical review on the buffer zone which can be useful for new researchers.
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  • 05 Jan 2021
Topic Review
Syngeneic Tumor Models
Developments in cancer immunotherapy mean that complex cancer animal models which accurately relfect the tumor and its environment are required now more than ever. Mice remain good animals to investigate as they are relatively inexpensive, have short reproductive cycle, exhibit high tumor growth rates, and can be genetically modified. Despite being good models, some drugs which look promising in murine models still fail when trialed in humans. Increasing reliability is essential and the tumor model must reflect the tumor and its microenvironment including immune cells, to which the action of immunotherapeutic drugs are directed. This review investigates discusses the current immunocompetent and immunocompromised mouse models used to evaluate the effectiveness of immunotherapeutic agents, in particular chimeric antigen receptor (CAR) T-cells and immune checkpoint inhibitors.
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  • 09 Nov 2020
Topic Review
Citizen-Centric Smart Cities
The citizen-centric smart city is conceptualised from the citizenship perspective which stressed on the citizen's responsibilities and participatory governance practices in a smart city (Malek, Lim and Yigitcanlar, 2021). This conception argues that instead of the traditional view on fulfilling the citizen's needs, the citizens should co-produce, participate and contribute to building the smart city together with the government and corporates.
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  • 14 Sep 2021
Topic Review
COVID-19 Vaccine
A COVID‑19 vaccine is a hypothetical vaccine in development against coronavirus disease 2019 (COVID‑19). Although no candidate has completed clinical trials to prove its safety and efficacy, there are multiple efforts in progress to develop one. As of July 2020, there are 24 vaccine candidates planned or undergoing clinical trials, with two beginning Phase III and seven in Phase I-II. Previous attempts to develop a vaccine against the coronavirus diseases SARS and MERS established considerable knowledge about the structure and function of coronaviruses – which accelerated rapid development during early 2020 of varied technology platforms for a COVID‑19 vaccine – but all the previous coronavirus vaccine candidates failed in early-stage clinical trials, with none being advanced to licensing. The Coalition for Epidemic Preparedness Innovations (CEPI) – which is organizing a US$2 billion worldwide fund for rapid investment and development of vaccine candidates – indicated in April that a vaccine may be available under emergency use protocols in less than 12 months or by early 2021. On 4 May 2020, the WHO organized a telethon which received US$8.1 billion in pledges from forty countries to support rapid development of vaccines to prevent COVID‑19 infections. At the same time, the WHO also announced deployment of an international "Solidarity trial" for simultaneous evaluation of several vaccine candidates reaching Phase II-III clinical trials.
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  • 09 Nov 2022
Topic Review
Turtles in Malaysia
Approximately 356 species of turtles inhabit saltwater and freshwater habitats globally, except in Antarctica. Twenty-four species of turtles have been reported in Malaysia, four of which are sea turtles. The state of Terengganu harbored the highest number of turtles, with 17 different reported species. 
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  • 19 Sep 2022
Topic Review
Acacia spp.
The genus Acacia belongs to the subfamily Mimosoideae of the family Fabaceae. It comprises a large group of more than 1350 species, widely distributed throughout tropical and warm temperate areas of the world. Most of the species are native to Australia but are spread all over the world because of their wide variety of uses and economic importance such as for ornamental purposes, for sand and dune stabilization, as a fuel through the production of woodfuel and charcoal, as an important source of fodder, tannins for the leather industry, gums, and essences for perfumes.
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  • 10 Feb 2021
Topic Review
Influencer Marketing
Influencer marketing (also known as influence marketing) is a form of social media marketing involving endorsements and product placement from influencers, people and organizations who have a purported expert level of knowledge or social influence in their field. Influencers are someone (or something) with the power to affect the buying habits or quantifiable actions of others by uploading some form of original—often sponsored—content to social media platforms like Instagram, YouTube, Snapchat or other online channels. Influencer marketing is when a brand enrolls influencers who have an established credibility and audience on social media platforms to discuss or mention the brand in a social media post. Influencer content may be framed as testimonial advertising.
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  • 14 Oct 2022
Topic Review
Lingua Geographica
Geographic tongue, also known by several other terms,[note 1] is a condition of the mucous membrane of the tongue, usually on the dorsal surface. It is a common condition, affecting approximately 2–3% of the general population. It is characterized by areas of smooth, red depapillation (loss of lingual papillae) which migrate over time. The name comes from the map-like appearance of the tongue, with the patches resembling the islands of an archipelago. The cause is unknown, but the condition is entirely benign (importantly, it does not represent oral cancer), and there is no curative treatment. Uncommonly, geographic tongue may cause a burning sensation on the tongue, for which various treatments have been described with little formal evidence of efficacy.
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  • 26 Oct 2022
Topic Review
Deep Reinforcement Learning Approaches for Smart Manufacturing
AI and, in particular, the Deep Reinforcement Learning (DRL) algorithms, which are a perfect response to the unpredictability and volatility of modern demand, are studied in detail. Through the introduction of RL concepts and the development of those with ANNs towards DRL, the potential and variety of these kinds of algorithms are highlighted. Moreover, because these algorithms are data based, their modification to meet the requirements of industry operations is also included. Digital twins are a technology that is increasingly important in I.40 and I.5.0, which seems to be crucial to the development of smart manufacturing. 
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  • 13 Jan 2023
Topic Review
Bambara Groundnut for Food Security
Bambara groundnut is one such imperative and neglected legume crop that contributes positively to improving global food and nutrient safety. As a “complete food”, this crop has recently been treated as a new millennium crop, and furthermore, it is more adjusted to poor soil and climatic conditions than other dominant crops. Bambara groundnut is a repository of vital nutrients that provides carbohydrates, crucial amino acids, proteins, and energy as well as minerals and vitamins to developed and low-income countries where animal proteins are not readily available. 
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  • 28 May 2021
Topic Review
Applications of Biomimetic Propulsion for Underwater Vehicles
Biomimetics and bio-inspiration, distinct yet complementary, both derive insights from nature’s ingenuity in science and engineering. Biomimetics, specifically for underwater vehicles, studies and emulates the efficient shapes and behaviors of aquatic creatures like fishes, dolphins, and whales, leading to innovative underwater vehicle designs with enhanced speed, thrust, maneuverability, and reduced water drag.
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  • 04 Feb 2024
Topic Review
Removal of Inorganic Nitrogen from Wastewater
Water contamination due to various nitrogenous pollutants generated from wastewater treatment plants is a crucial and ubiquitous environmental problem nowadays. Nitrogen contaminated water has manifold detrimental effects on human health as well as aquatic life. Consequently, various biological and bioelectrochemical treatment processes are employed to transform the undesirable forms of nitrogen in wastewater to safer ones for subsequent discharge.
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  • 27 May 2022
Topic Review Peer Reviewed
SARS, MERS and COVID-19-Associated Renal Pathology
Coronaviruses are a large group of RNA viruses, the most notable representatives of which are SARS-CoV, MERS-CoV and SARS-CoV-2. Human coronavirus infections were first documented in the 1960s, when members causing seasonal common colds were successfully replicated in human embryonal trachea and kidney cell cultures and classified based on electron microscopy. The history of coronaviruses stretched far back to that point, however, with some representatives causing disease in animals identified several decades prior and evolutionary data pointing towards the origin of this viral group more than 55 million years ago. In the short time period of research since they were discovered, coronaviruses have shown significant diversity, genetic peculiarities and varying tropism, resulting in the three identified causative agents of severe disease in humans—SARS, MERS and the most recent one, COVID-19, which has surpassed the previous two due to causing a pandemic resulting in significant healthcare, social and political consequences. Coronaviruses are likely to have caused pandemics long before, such as the so-called Asian or Russian influenza. Despite being epitheliotropic viruses and predominantly affecting the respiratory system, these entities affect multiple systems and organs, including the kidneys. In the kidneys, they actively replicate in glomerular podocytes and epithelial cells of the tubules, resulting in acute kidney injury, seen in a significant percentage of severe and fatal cases. Furthermore, the endothelial affinity of the viruses, resulting in endotheliitis, increases the likelihood of thrombotic microangiopathy, damaging the kidneys in a two-hit mechanism. As such, recently, COVAN has been a suggested nomenclature change indicating renal involvement in coronavirus infections and its long-lasting consequences. 
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  • 10 Oct 2022
Topic Review
Localization of a Ring
In commutative algebra, localization is a systematic method of adding multiplicative inverses to a ring. Given a ring R and a subset S, one wants to construct some ring R* and ring homomorphism from R to R*, such that the image of S consists of units (invertible elements) in R*. Further one wants R* to be the 'best possible' or 'most general' way to do this—in the usual fashion this should be expressed by a universal property. The localization of R by S is usually denoted by S −1R; however other notations are used in some important special cases. If S is the set of the non zero elements of an integral domain, then the localization is the field of fractions and thus usually denoted Frac(R). If S is the complement of a prime ideal I the localization is denoted by RI, and Rf is used to denote the localization by the powers of an element f. The two latter cases are fundamental in algebraic geometry and scheme theory. In particular the definition of an affine scheme is based on the properties of these two kinds of localizations.
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  • 26 Oct 2022
Topic Review
Australian Raven
The Australian raven (Corvus coronoides) is a passerine bird in the genus Corvus native to much of southern and northeastern Australia. Measuring 46–53 centimetres (18–21 in) in length, it has all-black plumage, beak and mouth, as well as strong grey-black legs and feet. The upperparts are glossy, with a purple, blue, or green sheen, and its black feathers have grey bases. The Australian raven is distinguished from the Australian crow species by its throat hackles, which are prominent in adult birds. Older adult individuals have white irises, younger adults have white irises with an inner blue rim, while younger birds have dark brown irises until fifteen months of age, and hazel irises with an inner blue rim around each pupil until age two years and ten months. Nicholas Aylward Vigors and Thomas Horsfield described the Australian raven in 1827, its species name (coronoides) highlighting its similarity with the carrion crow (C. corone). Two subspecies are recognized, which differ slightly in calls and are quite divergent genetically. The preferred habitat is open woodland and transitional zones. It has adapted well to urban environments and is a common city bird in Sydney, Canberra, and Perth. An omnivorous and opportunistic feeder, it eats a wide variety of plant and animal material, as well as food waste from urban areas. In eastern Australia, its range is strongly correlated with the presence of sheep, and it has been blamed for killing lambs. However, this is very rare, and the raven most often scavenges for afterbirth and stillborn animals as well as newborn lamb faeces. The Australian raven is territorial, with pairs generally bonding for life. Breeding takes place between July and September, with almost no variation across its range. The nest is a bowl-shaped structure of sticks sited high in a tree, or occasionally in a man-made structure such as a windmill or other building. File:An audio recording of an Australian Raven (Corvus coronoides).wav
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  • 21 Nov 2022
Topic Review
BFlix UK: Revolutionizing the British Streaming Industry
BFlix UK has made a significant impact on the British streaming industry in a relatively short period. With its focus on local content, user-centric technology, and strategic partnerships, it has managed to stand out in a crowded market. As it continues to innovate and expand, BFlix UK has the potential to become a major player not just in the UK, but in the global streaming arena.
  • 3.1K
  • 31 Oct 2024
Topic Review
List of Minerals Approved by IMA (T)
This list includes those recognised minerals beginning with the letter T. The International Mineralogical Association is the international group that recognises new minerals and new mineral names, however minerals discovered before 1959 did not go through the official naming procedure, although some minerals published previously have been either confirmed or discredited since that date. This list contains a mixture of mineral names that have been approved since 1959 and those mineral names believed to still refer to valid mineral species (these are called "grandfathered" species). The data was exported from mindat.org on 29 April 2005; updated up to 'IMA2018'. The minerals are sorted by name, followed by the structural group (rruff.info/ima and ima-cnmnc by mineralienatlas.de, mainly) or chemical class (mindat.org and basics), the year of publication (if it's before of an IMA approval procedure), the IMA approval and the Nickel–Strunz code.
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  • 09 Oct 2022
Topic Review
Literature
This is a list of encyclopedias as well as encyclopedic and biographical dictionaries published on the subject of literature in any language.
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  • 28 Apr 2023
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