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Topic Review
Application of Citric Acid in the Food Industry
Citric acid finds broad applications in various industrial sectors, such as the pharmaceutical, food, chemical, and cosmetic industries. The bioproduction of citric acid uses various microorganisms, but the most commonly employed ones are filamentous fungi such as Aspergillus niger and yeast Yarrowia lipolytica.
  • 3.8K
  • 10 Jan 2024
Topic Review
Acinar Cells for Pancreatic Cancer
The carcinogenesis of pancreatic ductal adenocarcinoma (PDA) progresses according to multi-step evolution, whereby the disease acquires increasingly aggressive pathological features. Lineage-tracing experiments demonstrated that pancreatic cancerous lesions originate from acinar cells, a highly specialized cell type in the pancreatic epithelium. Acinar cells are polarized, pyramidal-shaped cells containing numerous acidophilic granules near the apical side. Those granules contain inactive proteases, which are activated and released into the tubular network upon activation. Primary acinar cells can survive in vitro as organoid-like 3D spheroids, which can transdifferentiate into cells with a clear ductal morphology in response to different cell- and non-cell-autonomous stimuli.This event, termed acinar-to-ductal metaplasia, recapitulates the histological and molecular features of disease initiation.
  • 3.8K
  • 24 Sep 2020
Topic Review
105×617mm
The 105×617mm (4.1 inch) also known as 105 × 617 R is a common, NATO-standard, tank gun cartridge used in 105mm guns such as those derived from the Royal Ordnance L7. The 105 × 617 R cartridge was originally developed from the 84 mm (3.3 in) calibre Ordnance QF 20-pounder 84 × 618R cartridge as part of the development of the L7 105 mm rifled gun.
  • 3.8K
  • 03 Nov 2022
Topic Review
'Phags-Pa Script
The ‘Phags-pa script (Mongolian: дөрвөлжин үсэг "Square script") is an alphabet designed by the Tibetan monk and State Preceptor (later Imperial Preceptor) Drogön Chögyal Phagpa for Kublai Khan, the founder of the Yuan dynasty, as a unified script for the written languages within the Yuan. The actual use of this script was limited to about a hundred years during the Mongol Yuan dynasty, and it fell out of use with the advent of the Ming dynasty. The documentation of its use provides clues about the changes in the varieties of Chinese, the Tibetic languages, Mongolian and other neighboring languages during the Yuan era.
  • 3.8K
  • 09 Nov 2022
Topic Review
Types of Supercapacitors
Supercapacitors are mainly divided into three types: electrical double layer (EDL) capacitors, pseudocapacitors, and hybrid supercapacitors based on their energy storage mechanisms. 
  • 3.8K
  • 27 Apr 2023
Topic Review
Canis Major
Canis Major, Latin for "Greater Dog," is one of the most prominent constellations in the southern celestial hemisphere. Often depicted as one of Orion's hunting dogs in Greek mythology, Canis Major is best known for its brightest star, Sirius, also called the Dog Star, which is the brightest star in the night sky. With its distinctive shape and rich cultural significance, Canis Major has fascinated astronomers and storytellers throughout history.
  • 3.8K
  • 29 Feb 2024
Topic Review
Synthesis and Characteristics of PEDOT:PSS and PEDOT:Carrageenan
Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) has been mostly used as a counter electrode to give a high performance of dye-sensitized solar cell (DSSC). PEDOT doped by carrageenan, namely PEDOT:Carrageenan, was introduced as a new material to be applied on DSSC as an electrolyte. PEDOT:Carrageenan has a similar synthesis process as PEDOT:PSS, owing to their similar ester sulphate (-SO3H) groups in both PSS and carrageenan. 
  • 3.8K
  • 17 Jul 2023
Topic Review
Opal
Opal is a hydrated amorphous form of silica (SiO2·nH2O); its water content may range from 3 to 21% by weight, but is usually between 6 and 10%. Because of its amorphous character, it is classed as a mineraloid, unlike crystalline forms of silica, which are classed as minerals. It is deposited at a relatively low temperature and may occur in the fissures of almost any kind of rock, being most commonly found with limonite, sandstone, rhyolite, marl, and basalt. The name opal is believed to be derived from the Sanskrit word upala (उपल), which means 'jewel', and later the Greek derivative opállios (ὀπάλλιος), which means 'to see a change in color'. There are two broad classes of opal: precious and common. Precious opal displays play-of-color (iridescence); common opal does not. Play-of-color is defined as "a pseudo chromatic optical effect resulting in flashes of colored light from certain minerals, as they are turned in white light." The internal structure of precious opal causes it to diffract light, resulting in play-of-color. Depending on the conditions in which it formed, opal may be transparent, translucent, or opaque, and the background color may be white, black, or nearly any color of the visual spectrum. Black opal is considered the rarest, while white, gray, and green opals are the most common.
  • 3.8K
  • 24 Oct 2022
Topic Review
Energy Piles
Energy piles are a relatively new technology that have dual function as heat transferring and load bearing. Due to the influence of temperature cycles, additional thermal stress and relative displacement of the pile will be generated; this is different from the load transferring mechanism of the conventional pile. In order to study the thermodynamic characteristics of the energy pipe pile under dual working conditions and temperature cycles, field tests were carried out on the PHC (prestressed high-strength concrete) energy pipe pile without constraining on the top of the piles. Displacement gauges were arranged on the top of the pile, and concrete strain gauges (temperature, strain) were embedded in the pile.
  • 3.8K
  • 31 Jul 2021
Topic Review
Power Quality Measurement
The use of power networks can induce harmonic pollution, disturbances, and power quality events within a power grid, leading to abnormal operating conditions of equipment and materials. It is, therefore, mandatory to characterize power quality disturbances in order to enhance the power system’s efficiency and reliability.
  • 3.7K
  • 19 Nov 2021
Topic Review
Chitosan and Chitosan Modified by Functionalization
The biomedical and therapeutic importance of chitosan and chitosan derivatives is the subject of interdisciplinary research. In this entry, researchers intended to consolidate some of the recent discoveries regarding the potential of chitosan and its derivatives to be used for biomedical and other purposes. Why chitosan? Because chitosan is a natural biopolymer that can be obtained from one of the most abundant polysaccharides in nature, which is chitin. Compared to other biopolymers, chitosan presents some advantages, such as accessibility, biocompatibility, biodegradability, and no toxicity, expressing significant antibacterial potential. In addition, through chemical processes, a high number of chitosan derivatives can be obtained with many possibilities for use. 
  • 3.7K
  • 02 Apr 2022
Topic Review Peer Reviewed
Metal Nanoparticles as Free-Floating Electrodes
Colloidal metal nanoparticles in an electrolyte environment are not only electrically charged but also electrochemically active objects. They have the typical character of metal electrodes with ongoing charge transfer processes on the metal/liquid interface. This picture is valid for the equilibrium state and also during the formation, growth, aggregation or dissolution of nanoparticles. This behavior can be understood in analogy to macroscopic mixed-electrode systems with a free-floating potential, which is determined by the competition between anodic and cathodic partial processes. In contrast to macroscopic electrodes, the small size of nanoparticles is responsible for significant effects of low numbers of elementary charges and for self-polarization effects as they are known from molecular systems, for example. The electrical properties of nanoparticles can be estimated by basic electrochemical equations. Reconsidering these fundamentals, the assembly behavior, the formation of nonspherical assemblies of nanoparticles and the growth and the corrosion behavior of metal nanoparticles, as well as the formation of core/shell particles, branched structures and particle networks, can be understood. The consequences of electrochemical behavior, charging and self-polarization for particle growth, shape formation and particle/particle interaction are discussed.
  • 3.7K
  • 13 Apr 2022
Topic Review
Chemical and Physical Properties of Solid Salt Fluxes
Solid salt fluxes are inorganic compounds that are added during the treatment of molten aluminum to improve the final quality. An understanding of the chemical composition of the flux is essential for the assessment of the physical and chemical behavior of the flux. The chemical composition of the flux can be tailored to adjust properties such as density, viscosity, reactivity, and wettability. Such properties, in turn, will impart different functions to the flux. 
  • 3.7K
  • 05 May 2023
Topic Review
Technical Lignin
Lignin, the term commonly used in literature, represents a group of heterogeneous aromatic compounds of plant origin. 
  • 3.7K
  • 16 Feb 2021
Topic Review
Land Surface Model
Land Surface Models (LSMs) are important components of the climate models, which help to capture the water, energy, and momentum exchange between the land surface and the atmosphere, providing lower boundary conditions to the atmospheric models.
  • 3.7K
  • 02 Apr 2021
Topic Review
Honey and Propolis in Ocular Disease Treatment
Honey and propolis have recently become the key target of attention for treating certain diseases and promoting overall health and well-being. A high content of flavonoids and phenolic acids found in both honey and propolis contributes to the antioxidant properties to scavenge free radicals. Honey and propolis also exhibited antibacterial effects where they act in two ways, namely the production of hydrogen peroxide (H2O2) and gluconic acids following the enzymatic activities of glucose oxidase, which exerts oxidative damage on the bacteria. Additionally, the anti-inflammatory effects of honey and propolis are mainly by reducing proinflammatory factors such as interleukins and tumor necrosis factor alpha (TNF-α). Their effects on pain were discovered through modulation at a peripheral nociceptive neuron or binding to an opioid receptor in the higher center. The aforementioned properties of honey have been reported to possess potential therapeutic topical application on the exterior parts of the eyes, particularly in treating conjunctivitis, keratitis, blepharitis, and corneal injury. In contrast, most of the medicinal values of propolis are beneficial in the internal ocular area, such as the retina, optic nerve, and uvea. 
  • 3.7K
  • 02 Feb 2023
Topic Review Video Peer Reviewed
Unraveling Neurodiversity: Insights from Neuroscientific Perspectives
Neurodiversity is a concept and a social movement that addresses and normalizes human neurocognitive heterogeneity to promote acceptance and inclusion of neuro-minorities (e.g., learning disabilities, attention disorders, psychiatric disorders, and more) in contemporary society. Neurodiversity is attributed to nature and nurture factors, and about a fifth of the human population is considered neurodivergent. What does neurodiversity mean neuroscientifically? This question forms the foundation of the present entry, which focuses on existing scientific evidence on neurodiversity including neurodiversity between and within individuals, and the evolutional perspective of neurodiversity. Furthermore, the neuroscientific view will be synergistically integrated with social approaches, particularly in the context of the normalization of neurodiversity and its association with the medical and social models of disability. This multidimensional analysis offers a cohesive and comprehensive understanding of neurodiversity, drawing insights from various vantage points, such as social, psychological, clinical, and neuroscientific viewpoints. This integrated approach fosters a nuanced and holistic discussion on the topic of human diversity.
  • 3.7K
  • 10 Aug 2023
Topic Review
Peptide for Bone and Cartilage Regeneration
The healing of osteochondral defects (OCDs) that result from injury, osteochondritis, or osteoarthritis and bear lesions in the cartilage and bone, pain, and loss of joint function in middle- and old-age individuals presents challenges to clinical practitioners because of non-regenerative cartilage and the limitations of current therapies. Bioactive peptide-based osteochondral (OC) tissue regeneration is becoming more popular because it does not have the immunogenicity, misfolding, or denaturation problems associated with original proteins. 
  • 3.7K
  • 19 Mar 2024
Topic Review
Terma (Religion)
Terma (Tibetan: གཏེར་མ་, Wylie: gter ma; "hidden treasure") are various forms of hidden teachings that are key to Vajrayana or Tibetan Buddhist and Bon religious traditions. The belief is that these teachings were originally esoterically hidden by various adepts such as Padmasambhava and dakini such as Yeshe Tsogyal (consorts) during the 8th century, for future discovery at auspicious times by other adepts, who are known as tertöns. As such, terma represent a tradition of continuous revelation in Vajrayana or Tibetan Buddhism. Termas are a part of tantric literature.
  • 3.7K
  • 26 Oct 2022
Topic Review
TI MSP430
The MSP430 is a mixed-signal microcontroller family from Texas Instruments, first introduced on 14 February 1992. Built around a 16-bit CPU, the MSP430 is designed for low cost and, specifically, low power consumption embedded applications.
  • 3.7K
  • 16 Nov 2022
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