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Topic Review
Herbalism
Herbalism (also herbal medicine) is the study of botany and use of plants intended for medicinal purposes. Plants have been the basis for medical treatments through much of human history, and such traditional medicine is still widely practiced today. Modern medicine makes use of many plant-derived compounds as the basis for evidence-based pharmaceutical drugs. Although phytotherapy may apply modern standards of effectiveness testing to herbs and medicines derived from natural sources, few high-quality clinical trials and standards for purity or dosage exist. The scope of herbal medicine is sometimes extended to include fungal and bee products, as well as minerals, shells and certain animal parts. The term, phytomedicine, may also refer to the science of pathology and damage to plants, the causes thereof, their manifestations, development, dissemination, methods for maintaining plant health, and measures used to control plant diseases and their causes. Herbal medicine is sometimes also used to refer to paraherbalism or phytotherapy, which is the alternative and pseudoscientific practice of using of extracts of plant or animal origin as supposed medicines or health-promoting agents. Phytotherapy differs from plant-derived medicines in standard pharmacology because it does not isolate and standardize the compounds from a given plant believed to be biologically active. It relies on the false belief that preserving the complexity of substances from a given plant with less processing is safer and potentially more effective. There is no evidence that either condition applies. Herbal dietary supplements most often fall under this category.
  • 4.4K
  • 11 Oct 2022
Topic Review
Guava: nutritional profile and opportunities
Guava (Psidium guajava L.), is a fruit considered native to the American tropics. It is of great economic importance in many countries of the world, due to its high production and diversity of products derived from its fruit. It can be consumed fresh or processed.
  • 4.4K
  • 12 Jul 2021
Topic Review Peer Reviewed
Wooden Additional Floor in Finland
One of the most effective ways to cover real estate development and renovation processes by improving functionality and energy efficiency is wooden additional floor construction. The scattered information is mapped out, organized, and collated on the current state of the art and the benefits of this practice including its different stages, focusing on the case of Finland. The topic is presented in an accessible and understandable discourse for non-technical readers. By highlighting the benefits and opportunities of this sustainable application, it will contribute to increasing the awareness of wooden additional floor construction, which has many advantages, and therefore to gain more widespread use in Finland and other countries.
  • 4.4K
  • 14 Apr 2022
Topic Review
Cocaine
Cocaine is one of the most consumed stimulants throughout the world, as official sources report. It is a naturally occurring sympathomimetic tropane alkaloid derived from the leaves of Erythroxylon coca, which has been used by South American locals for millennia. Cocaine can usually be found in two forms, cocaine hydrochloride, a white powder, or ‘crack’ cocaine, the free base. 
  • 4.4K
  • 27 Apr 2022
Topic Review
Synechocystis sp.: A Model Microorganism
Synechocystis sp. is a unicellular, spherical, non-nitrogen-fixing cyanobacterium with 0.7–8 µm in diameter and no or fine and colorless mucilage layer . The cell envelop of Synechocystis sp. contains the outer membrane, a peptidoglycan layer, and cytoplasmic membrane. The thylakoid membranes, derived from the cytoplasmic membrane, cover the peripheral region of the cell . From cyanobacteria to higher plants, thylakoid membranes are the site of photosynthesis converged near the cytoplasmic membrane. Thylakoid centers, fibrous coated cylindrical structures, 40–50 nm in diameter and 50–1000 nm in length, establish and maintain thylakoid membrane organization
  • 4.4K
  • 15 Apr 2022
Topic Review
Sustainable Consumer Behavior
Sustainable Consumer Behavior, namely a new sustainable consumer model, refers to major shifts in buying and consumption habits. Nevertheless, these shifts were lagging as consumers resisted change in the comfort of old habits. This comfort was shaken up by the COVID-19 outbreak that forced us to rethink every aspect of our lives. Therefore, this crisis context seems the perfect opportunity to shift towards the sustainable consumer model.
  • 4.4K
  • 09 Jun 2021
Topic Review
Anatomy of the Rumen Affecting the Microbiome
The rumen is a complex organ that is critical for its host to convert low-quality feedstuffs into energy. The conversion of lignocellulosic biomass to volatile fatty acids and other end products is primarily driven by the rumen microbiome and its interaction with the host. Importantly, the rumen is demarcated into five distinct rumen sacs as a result of anatomical structure, resulting in variable physiology among the sacs. 
  • 4.3K
  • 23 Mar 2023
Topic Review
International Harvester Metro Van
International Harvester's Metro Van is a step van, also known as walk-in or multi-stop delivery truck. This vehicle type was one of the earlier, mass-produced forward control vehicles, once commonly used for milk or bakery delivery, as well as ambulance services, mobile offices, and radio transmitter vans. Typically, they were 1/2-, 3/4-, or 1-ton panel trucks that allowed the driver to stand or sit while driving the vehicle. Variations included a passenger bus called a Metro Coach, a Metro partial cab-chassis with front-end sections (for end-user customization), and a cab-over truck called a "walk-in cab". The truck (also called a chassis cab) variation could be configured with a separate box or container for cargo transport or left open to be fitted with other equipment such as a compactor for a garbage truck or a stake bed.
  • 4.3K
  • 05 Dec 2022
Topic Review
Tudor Rose
The Tudor rose (sometimes called the Union rose) is the traditional floral heraldic emblem of England and takes its name and origins from the House of Tudor, which united the House of Lancaster and the House of York. The Tudor rose consists of five white inner petals, representing the House of York, and five red outer petals to represent the House of Lancaster.
  • 4.3K
  • 16 Nov 2022
Topic Review
Methanol
Methanol, an alcohol with an odor similar to that of ethanol, has been described to exist in low concentrations in the human organism and occurs naturally at a low level in most spirits, without conferring health risk if it exists within the legal limits. 
  • 4.3K
  • 20 Jan 2021
Topic Review
A Certain Magical Index
A Certain Magical Index (Japanese: とある魔術の禁書目録 (インデックス), Hepburn: Toaru Majutsu no Indekkusu)[lower-alpha 1] is a Japanese light novel series written by Kazuma Kamachi and illustrated by Kiyotaka Haimura, which has been published by ASCII Media Works under their Dengeki Bunko imprint since April 2004. The plot is set in a world where supernatural abilities exist. The light novels focus on Toma Kamijo, a young high school student in Academy City who has an unusual ability, as he encounters an English nun named Index. His ability and relationship with Index proves dangerous to other sorcerers and Espers who want to discover the secrets behind him and Index, as well as the city. Yen Press have licensed the novels in North America. A manga adaptation by Chuya Kogino began serialization in Monthly Shōnen Gangan from May 2007. J.C.Staff produced two 24-episode anime series between 2008 and 2011. An animated film was released in February 2013. The anime adaptations are licensed in North America by Funimation. A 26-episode third season aired between 2018 and 2019, licensed by Funimation. The side-story manga series, A Certain Scientific Railgun, began serialization in Dengeki Daioh in February 2007. A second side-story manga series, A Certain Scientific Accelerator, began serialization in Dengeki Daioh in December 2013.
  • 4.3K
  • 19 Oct 2022
Topic Review
Weather Radar
The history of Weather Radar (abbreviation of RAdio Detecting And Ranging) begins during World War II, when military radar operators noticed extraneous echoes showing up on their display. David Atlas was one of the pioneers of radar meteorology, along with John Stewart Marshall, Walter Palmer and Richard Doviak. Weather radars send pulses of electromagnetic energy into the atmosphere, a microsecond of long microwave radiation to identify the presence of hydrometeors.
  • 4.3K
  • 17 Feb 2022
Topic Review
Vocabulary Development
Vocabulary development is a process by which people acquire words. Babbling shifts towards meaningful speech as infants grow and produce their first words around the age of one year. In early word learning, infants build their vocabulary slowly. By the age of 18 months, infants can typically produce about 50 words and begin to make word combinations. In order to build their vocabularies, infants must learn about the meanings that words carry. The mapping problem asks how infants correctly learn to attach words to referents. Constraints theories, domain-general views, social-pragmatic accounts, and an emergentist coalition model have been proposed to account for the mapping problem... From an early age, infants use language to communicate. Caregivers and other family members use language to teach children how to act in society. In their interactions with peers, children have the opportunity to learn about unique conversational roles. Through pragmatic directions, adults often offer children cues for understanding the meaning of words. Throughout their school years, children continue to build their vocabulary. In particular, children begin to learn abstract words. Beginning around age 3–5, word learning takes place both in conversation and through reading. Word learning often involves physical context, builds on prior knowledge, takes place in social context, and includes semantic support. The phonological loop and serial order short-term memory may both play an important role in vocabulary development.
  • 4.3K
  • 14 Nov 2022
Topic Review
Runx2 and Osteoblasts
Runx2 is essential for osteoblast differentiation, chondrocyte maturation, and transdifferentiation of terminally differentiated chondrocytes into osteoblasts. During osteoblast differentiation, Runx2 is weakly expressed in uncommitted mesenchymal cells, and its expression is upregulated in preosteoblasts, reaches the maximal level in immature osteoblasts, and is down-regulated in mature osteoblasts. Runx2 enhances the proliferation of osteoblast progenitors by directly regulating Fgfr2 and Fgfr3. Runx2 enhances the proliferation of suture mesenchymal cells and induces their commitment into osteoblast lineage cells through the direct regulation of hedgehog (Ihh, Gli1, and Ptch1), Fgf (Fgfr2 and Fgfr3), Wnt (Tcf7, Wnt10b, and Wnt1), and Pthlh (Pthr1) signaling pathway genes, and Dlx5. Runx2 heterozygous mutation causes open fontanelle and sutures because more than half of the Runx2 gene dosage is required for the induction of these genes in suture mesenchymal cells. Runx2 induces the proliferation of osteoblast progenitors and their differentiation into osteoblasts through reciprocal regulation via major signaling pathways, including Fgf, hedgehog, Wnt, and Pthlh, and transcription factors, including Sp7 and Dlx5. Runx2 also regulates the expression of bone matrix protein genes, including Col1a1, Col1a2, Spp1, and Bglap/Bglap2. Bglap/Bglap2 (osteocalcin) aligns biological apatite parallel to the collagen fibrils, which is important for bone strength, but osteocalcin does not play a role as a hormone in the pancreas, testis, and muscle. 
  • 4.3K
  • 22 Apr 2021
Topic Review
DKK1 in Hair Regeneration
Dickkopf-related protein 1 (DKK1) is distinctly identified as an inhibitor of canonical Wnt/β-catenin signaling.
  • 4.3K
  • 22 Nov 2021
Topic Review
Polymer-Derived Ceramics
Ceramics derived from organic polymer precursors, which have exceptional mechanical and chemical properties that are stable up to temperatures slightly below 2000 °C, are referred to as polymer-derived ceramics (PDCs).
  • 4.3K
  • 09 Feb 2021
Topic Review
Intraretinal Fluid Pattern Characterization
The accumulation of fluids in the retinal layers is one of the main causes of blindness in developed countries. The main strategy for its study and diagnosis is through the use of Optical Coherence Tomography (OCT) images. This allows experts to observe the layers of the retina in a cross-sectional view. Commonly, for the analysis of these accumulations by means of computer diagnostic support systems, precise segmentation strategies are employed.
  • 4.3K
  • 22 Apr 2021
Topic Review
Causes and Risk Factors of Alzheimer’s Disease
Alzheimer’s disease (AD) is a disorder that causes degeneration of the cells in the brain and it is the main cause of dementia, which is characterized by a decline in thinking and independence in personal daily activities. AD is considered a multifactorial disease: two main hypotheses were proposed as a cause for AD, cholinergic and amyloid hypotheses. Additionally, several risk factors such as increasing age, genetic factors, head injuries, vascular diseases, infections, and environmental factors play a role in the disease.
  • 4.3K
  • 29 Feb 2024
Topic Review
Plagioclase
Plagioclase is a series of tectosilicate (framework silicate) minerals within the feldspar group. Rather than referring to a particular mineral with a specific chemical composition, plagioclase is a continuous solid solution series, more properly known as the plagioclase feldspar series. This was first shown by the German mineralogist Johann Friedrich Christian Hessel (1796–1872) in 1826. The series ranges from albite to anorthite endmembers (with respective compositions NaAlSi3O8 to CaAl2Si2O8), where sodium and calcium atoms can substitute for each other in the mineral's crystal lattice structure. Plagioclase in hand samples is often identified by its polysynthetic crystal twinning or 'record-groove' effect. Plagioclase is a major constituent mineral in the Earth's crust, and is consequently an important diagnostic tool in petrology for identifying the composition, origin and evolution of igneous rocks. Plagioclase is also a major constituent of rock in the highlands of the Moon. Analysis of thermal emission spectra from the surface of Mars suggests that plagioclase is the most abundant mineral in the crust of Mars. Its name comes from Ancient Greek plágios (πλάγιος 'oblique') + klásis ((κλάσις 'fracture'), in reference to its two cleavage angles.
  • 4.3K
  • 25 Nov 2022
Topic Review
List of Intel Core I7 Microprocessors
The following is a list of Intel Core i7 brand microprocessors. Introduced in 2008, the Core i7 line of microprocessors are intended to be used by high-end users.
  • 4.3K
  • 24 Nov 2022
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