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Topic Review
Obstructive Sleep Apnea(OSA)
Obstructive sleep apnea (OSA) is a common sleep disorder that affects all age groups and is associated with many co-morbid diseases (especially cardiovascular diseases). Continuous positive airway pressure (CPAP) is the gold standard for treating OSA. However, and with increasing prevalence of CPAP non-adherence, other therapeutic interventions have emerged. Hypoglossal nerve stimulation is a novel modality of treating patients with moderate to severe OSA who are not adherent to CPAP.
  • 758
  • 02 Mar 2021
Topic Review
Factors Associated with HIV and Syphilis Co-Infection
Human immunodeficiency virus (HIV)–syphilis co-infection poses a threat to certain populations, and patients may have considerably poorer health outcomes due to these infections. Males—particularly men who have sex with men—compose the overwhelming majority of co-infected cases. Additional risk factors include a low CD4 cell count, current or past sexually transmitted infections, and a high number of sexual partners. 
  • 753
  • 27 May 2022
Topic Review
Polyfluoroalkyl Substances (PFAS) Ban
The proposal by the European Chemicals Agency (ECHA) to ban over 12,000 per- and polyfluoroalkyl substances (PFAS) has sparked a debate about potential consequences for the economy, industry, and the environment. Although some PFAS are known to be harmful, a blanket ban may lead to significant problems in attempting to replace PFAS-based materials for environmental transition, as well as in medical devices and everyday products.
  • 753
  • 10 Nov 2023
Topic Review
Brucella melitensis Vaccines
Brucella melitensis is recognized as one of the predominant zoonotic pathogens globally. Live-attenuated vaccine Rev 1 is currently the most effective vaccine for controlling B. melitensis in small ruminants. While Brucella inactivated, nanoparticle, and subunit vaccines are less effective and require multiple doses, live-attenuated vaccines are less expensive and more efficacious. Several drawbacks are associated with the administration of current attenuated B. melitensis vaccines, including interference with serological diagnostic tests, inducing abortion in pregnant animals, shedding in milk, and zoonotic infections in humans. 
  • 753
  • 06 Dec 2023
Topic Review
Cervical Cancer Screening
In Southeast Asia, cervical cancer is the second most common cancer in women. Low coverage for cervical cancer screening (CCS) becomes a roadblock to disease detection and treatment. Herein, we identified the barriers to and facilitators of cervical cancer screening among women living in SEA.
  • 752
  • 17 May 2021
Topic Review
Benefits of Exercise for Lowering Cardiovascular Stress Reactivity
Exaggerated cardiovascular reactivity to and delayed recovery from stress increase the risk of cardiovascular diseases in the future. It is evident that exercise training and aerobic fitness are associated with reduced cardiovascular reactivity and enhanced recovery from stress, but the effects with acute exercise are less characterized. This research sought to explore the range and variety of available studies using acute exercise to lower stress-induced cardiovascular reactivity and recovery. In general, acute exercise particularly of the moderate-intensity, aerobic type effectively reduced stress-induced Blood pressure (BP) reactivity in the healthy population and in those with high blood pressure. This shows that with just a single bout of exercise can help to lower cardiovascular reactivity in response to stress without having to undergo extensive exercise training. Further research would be recommended to establish if other forms of exercise intensity or type are equally beneficial to lower exaggerated cardiovascular responses to stress.
  • 751
  • 15 Apr 2022
Topic Review
Microbiota in Shaping Women’s Health
A properly colonized human microbiota contributes to the proper functioning of the body. The composition of the natural flora changes depending on age, health, living conditions, and the use of antimicrobial agents: antibiotics, disinfectants, and some cosmetics. The human body is diversely populated with microorganisms and undergoes constant changes under the influence of various factors, and its proper composition is extremely important for the proper functioning of the body.
  • 751
  • 09 Jan 2023
Topic Review
Students’ Negative Emotional Symptoms during COVID-19
The impact of the coronavirus pandemic on negative emotional symptoms has been serious with studies reporting high prevalence rates for these. Isolation, reduced social contact, duration of quarantine and restrictions, which are the characteristics of a lockdown, played an important role in increased negative emotional symptoms for students.
  • 750
  • 04 Jan 2022
Topic Review
Epidemiological Investigations on Health Effects in Toner-Manufacturing Workers
Adverse health effects can occur in occupational engagements in various industries, and there have been several reports on the contamination of work environments by long-term exposure to chemicals such as heavy metals and organic solvents. Dust has long caused serious health problems at workplaces such as coal mines, tunnel construction, arc welding, metal grinding, foundries, and quarries.
  • 746
  • 22 Nov 2022
Topic Review
LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae
Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require sophisticated computational analyses. In particular, the regulatory roles of lncRNAs in circadian clocks are far from being completely understood.
  • 741
  • 07 Dec 2021
Topic Review
Hand Sanitizer Gels
Hand hygiene is a crucial measure in the prevention and control of infections, and there is a growing awareness among individuals who are making a conscious effort to maintain hand cleanliness. With the advent of the SARS-CoV-2 outbreak, the demand for hand hygiene products has also gradually shifted towards those with antimicrobial properties. Among these products, hand sanitizer gels (HSGs) have gained considerable popularity as an efficient method of hand cleaning, due to their rapid drying and sustained antimicrobial efficacy. 
  • 736
  • 23 Aug 2023
Topic Review
Source of Discomfort in Police Officers
The importance of improving working conditions for the health and psychological health of police officers creates added value in terms of organizational performance and the quality of life of those in the organization. Protecting the psychological health of police officers could have a positive impact not only on the private lives of employees but also on the quality of the relations between police officers and the users of police services, which, in turn, may lead to an improvement in the services offered to citizens. It is therefore desirable that all police organizations become aware of the importance of psychosocial risk assessment for not only the protection of police officers’ health but also for the optimization of their responses to citizens’ requests.
  • 733
  • 27 May 2022
Topic Review
Anticancer Strategies Targeting JWA
JWA is a microtubule-associated protein and an environmental response gene. JWA has been identified as a potential therapeutic target for several cancers. 
  • 733
  • 08 Oct 2022
Topic Review
Fundamental/Longitudinal Life History Trade-Offs on Delay Discounting
Delay discounting (DD) was a product of two distinct life history trade-offs, reflecting both the trait-like quality and age-related development.  
  • 731
  • 05 May 2022
Topic Review
Syndromic Surveillance Systems for Mass Gatherings
As defined by the Centers for Disease Control and Prevention (CDC), public health surveillance is the “ongoing systematic collection, analysis, and interpretation of outcome-specific data for use in the planning, implementation, and evaluation of public health practice,” which has been instrumental in the reduction in mortality from exposure to infectious diseases and environmental toxins. The arm of public health surveillance that deals specifically with the early detection of disease outbreaks or clusters of adverse health emergencies is referred to as syndromic surveillance and can be defined as “an investigational approach where health department staff, assisted by automated data acquisition and generation of statistical alerts, monitor disease indicators in real-time or near-real-time to detect outbreaks of disease earlier than would otherwise be possible with traditional public health methods”.
  • 729
  • 22 Apr 2022
Topic Review
High-Polyphenol-Content Waters Using Biotechnological Approaches
Polyphenols and their intermediate metabolites are natural compounds that are spread worldwide. Polyphenols are antioxidant agents beneficial for human health, but exposure to some of these compounds can be harmful to humans and the environment. A number of industries produce and discharge polyphenols in water effluents. These emissions pose serious environmental issues, causing the pollution of surface or groundwater (which are used to provide drinking water) or harming wildlife in the receiving ecosystems. The treatment of high-polyphenol-content waters is mandatory for many industries.
  • 729
  • 16 Jan 2023
Topic Review
Children Health and Air Pollution
The developmental origins of health and disease (DOHaD) hypothesis links adverse fetal exposures with developmental mal-adaptations and morbidity later in life. Short- and long-term exposures to air pollutants are known contributors to health outcomes. Air pollution is an established risk factor for morbidity and mortality that affects the general population. The developmental origins of health and disease (DOHaD) hypothesis states that adverse fetal, infant, and childhood growth patterns are causally linked to disease development in adulthood. The literature on cardiovascular and metabolic, respiratory, allergic, and neuropsychological health outcomes, from prenatal development through early childhood, associated with early-life exposures to outdoor air pollutants, including traffic-related and wildfire-generated air pollutants are summarized.
  • 727
  • 26 Aug 2022
Topic Review
Corporate Climate Change Impacts and Due Diligence
Climate change has been described as one of the greatest threats to people and the planet. Its impacts affect virtually the entire spectrum of internationally recognised human rights as well as the environment in and of itself. In relation to human rights, there is a growing consensus that companies should exercise human rights due diligence in order to identify and prevent their actual and potential adverse impacts.
  • 727
  • 27 Sep 2023
Topic Review
Cardiometabolic Risk and Chronobiology
Cardiovascular disease (CVD) poses a serious health and economic burden worldwide. Modifiable lifestyle factors are a focus of research into reducing the burden of CVD, with diet as one of the most investigated factors. Specifically, the timing and regularity of food intake is an emerging research area, with approaches such as time-restricted eating (TRE) receiving much attention. 
  • 721
  • 09 Feb 2022
Topic Review
Promoting Physical Activity among Workers
Insufficient physical activity (PA) has been identified as a leading risk factor for premature and all-cause death, as well as non-communicable diseases. Employees, especially those with low occupational PA, are more vulnerable to physical inactivity, and studies in this population are scarce. However, employees may receive benefits for both health and work productivity from PA. Therefore, well-designed behavior change studies to promote PA in employees are urgently needed, especially during the COVID-19 pandemic. Intervention mapping (IM) was a useful tool to develop, implement, and evaluate behavior change interventions. 
  • 721
  • 08 Nov 2022
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