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Topic Review
Therapeutic Implications of Splanchnic Vein Thrombosis
Splanchnic vein thrombosis (SVT) includes portal (portal vein thrombosis, PVT), mesenteric (mesenteric vein thrombosis, MVT) and splenic vein thrombosis, and Budd-Chiari syndrome (BCS). SVT is generally classified as secondary to an identified risk factor or primitive, unprovoked, when causative factors cannot be identified. While much rarer than common venous thromboembolism (VTE), SVT is often challenging to clinicians for both the identification of the causal disorder and for its therapeutic management. The therapeutic approach of SVT is a clinical challenge and considers the manifestations and the site of thrombosis, the risk of SVT progression, recurrence and bleeding. The decision regarding when to start, as well as the type and the duration of anticoagulant therapy is often made empirically.
  • 1.2K
  • 09 May 2023
Topic Review
Foodborne Disease Caused by Salmonella
Foodborne disease caused by Salmonella is an important public health concern worldwide. Animal-based food, especially poultry meat, is the main source of human salmonellosis.
  • 1.2K
  • 22 Nov 2021
Topic Review
Assistive Technologies for Supporting Older Adults' Wellbeing
As people age, they are more likely to develop multiple chronic diseases and experience a decline in some of their physical and cognitive functions, leading to the decrease in their ability to live independently. Innovative technology-based interventions tailored to older adults’ functional levels and focused on healthy lifestyles are considered imperative. 
  • 1.2K
  • 15 Feb 2022
Topic Review
Telehealth and Artificial Intelligence during the COVID-19 Pandemic
Telemedicine enables clinical services to use information technology, video imaging, and telecommunication links to deliver healthcare services at a distance. In contrast to telemedicine, which is defined as the provision of medical services at a distance by a physician, telehealth is an umbrella word that encompasses telemedicine as well as a number of nonphysician services such as telenursing and telepharmacy. Telemedicine is often used for controlling chronic diseases such as cardiovascular diseases, diabetes mellitus, cancer, and mental disorders.
  • 1.2K
  • 07 Mar 2022
Topic Review
Healthcare Waste Management
Healthcare waste (HCW) disposal includes a multitude of disposal methods, including incineration, landfilling and chemical treatments. These rudimentary methods and their growing use present their own problems that negatively impact both the environment and, in turn, damage public health, thus contributing to a global healthcare crisis.
  • 1.2K
  • 28 Apr 2021
Topic Review
Pathogenetic Mechanisms of Hypertension–Brain-Induced Complications
Hypertension is well known to alter the structure and function of cerebral blood vessels not only through its haemodynamics effects but also for its relationships with endothelial dysfunction, oxidative stress and inflammation.
  • 1.2K
  • 09 Mar 2022
Topic Review
Hotspots and Frontiers of Urban Floods
Current research shows that the number of papers published in the field of urban flooding is generally increasing year by year, and the research focus has shifted from exploring hydrological processes to adopting advanced management measures to solve urban flooding problems. 
  • 1.2K
  • 15 Dec 2021
Topic Review
Short Vestibular and Cognitive Training for Dyslexia
Dyslexia is a common learning difficulty that does not compromise oral or nonverbal reasoning skills, and it is reported in 5–10% of school-aged children. In the literature, different theories have tried to explain the etiology of this disorder. Phonological impairment is the most known hypothesis for dyslexia; however, others researchers suggested that dyslexia could be due to cerebellar impairments. Interestingly, reading performance and arithmetic skills have been suggested to also be related to cerebellar activity. Several subsequent studies from our group and others examining postural performances in the dyslexia population supported this hypothesis, even if other researchers suggested that such an impairment occurred not only in dyslexia but also in subjects having other types of developmental disorders. A visual attentional deficit has also been reported by Facoetti et al.  and our group showed an abnormal oculomotor pattern in children with dyslexia. Based on these different theories, several researchers have tried to develop different training types in order to improve the reading abilities in children with dyslexia. 
  • 1.2K
  • 05 Nov 2021
Topic Review
Arboviral Disease Outbreaks in the Pacific Islands Countries
Arthropod-borne viral (arboviral) diseases are a significant global health problem accounting for >17% of all infectious disease cases and 1 million deaths worldwide annually. Arboviral diseases are infections caused by over 100 viruses belonging to the Flaviviridae, Togaviridae, Reoviridae, Bunyaviridae, Rhabdoviridae and Orthomyxoviridae families. These viruses are spread to humans through arthropods, including mosquitos, ticks, and flies.
  • 1.2K
  • 17 Jan 2022
Topic Review
Safety Training
The purpose of safety training in acquiring knowledge about safety at work is to obtain information about the hazards present in the workplace and the necessary measures worn or kept by employees to protect him/her from one or more hazards associated with the presence of dangerous or harmful factors in the work environment (types of PPE). 
  • 1.2K
  • 27 Oct 2021
Topic Review
Adverse Perinatal Outcomes in COVID-19 Infected Pregnant Women
Several adverse maternal, fetal, and neonatal effects were significantly higher in COVID-19 infected pregnant women than non-infected. These included maternal death, preeclampsia, cesarean section delivery, fetal distress, preterm birth, low birth weight, stillbirth, low Apgar score at the fifth minute, and admission to NICU. The comorbidity conditions had no added risk of being infected with COVID-19 infection during pregnancy. Therefore, a COVID-19 infected pregnant woman should be treated with special precautions to avoid and minimize the identified adverse events during perinatal care. 
  • 1.2K
  • 24 Jan 2022
Topic Review
Vascular Smooth Muscle Cells Model
Vascular remodeling is a prominent feature of pulmonary hypertension. This process involves increased muscularization of already muscularized vessels as well as neo-muscularization of non-muscularized vessels. The cell-of-origin of the newly formed vascular smooth muscle cells has been a subject of intense debate in recent years. Identifying these cells may have important clinical implications since it opens the door for attempts to therapeutically target the progenitor cells and/or reverse the differentiation of their progeny. 
  • 1.2K
  • 24 Aug 2021
Topic Review
Erectile Dysfunction and Its Impact on Relationships
Explore how effective partner communication can significantly aid in the treatment of erectile dysfunction (ED) in this insightful article from ED Generic Store. Delving into the importance of emotional connection, open dialogue, and mutual support, this piece offers practical guidance for couples navigating the complexities of ED together. Learn how fostering trust, sharing concerns, and exploring lifestyle changes can enhance intimacy and improve overall relationship satisfaction. Gain valuable insights into the role of professional help and the power of celebrating progress as partners work collaboratively towards overcoming ED and revitalizing their connection.
  • 1.2K
  • 09 May 2024
Topic Review
Natural Milk Microbiota
Profound bioactivities of raw breastmilk include benefits attributed to the dense and diverse natural microbiota, termed natural microbiota hereafter. Infants benefit from breastfeeding not just nutritionally, but by both ‘seeding and feeding’ the infant gut , providing microbes that seed the naïve gastrointestinal (GI or gut) ecosystem and nutritive components that feed both infant and microbial cells.
  • 1.2K
  • 11 Nov 2021
Topic Review
Helminth Management
Understanding and managing the risk posed by helminth eggs (HE) is a key concern for wastewater engineers and public health regulators. The treatment processes that produce recycled water from sewage at wastewater treatment plants (WWTPs) rely on achieving a defined log10 reduction value (LRV) in HE concentration during the production of recycled water from sewage to achieve the guideline concentration of ≤1.0 HE/L.
  • 1.2K
  • 25 Nov 2021
Topic Review
Automated Detection of Sleep Arousals from Polysomnography
Multiple types of sleep arousal account for a large proportion of the causes of sleep disorders. The detection of sleep arousals is very important for diagnosing sleep disorders and reducing the risk of further complications including heart disease and cognitive impairment. Sleep arousal scoring is manually completed by sleep experts by checking the recordings of several periods of sleep polysomnography (PSG), which is a time-consuming and tedious work. The development of efficient, fast, and reliable automatic sleep arousal detection system from PSG may provide powerful help for clinicians. This paper reviews the automatic arousal detection methods in recent years, which are based on statistical rules and deep learning methods.  
  • 1.2K
  • 11 Oct 2021
Topic Review
Receptor-Mediated Targeted Delivery of Surface-ModifiedNanomedicine in Breast Cancer
Breast cancer therapeutic intervention continues to be ambiguous owing to the lack of strategies for targeted transport and receptor-mediated uptake of drugs by cancer cells. In addition to this, sporadic tumor microenvironment, prominent restrictions with conventional chemotherapy, and multidrug-resistant mechanisms of breast cancer cells possess a big challenge to even otherwise optimal and efficacious breast cancer treatment strategies. Surface-modified nanomedicines can expedite the cellular uptake and delivery of drug-loaded nanoparticulate constructs through binding with specific receptors overexpressed aberrantly on the tumor cell.
  • 1.2K
  • 07 Feb 2022
Topic Review
The U.S. Food and Drug Administration (FDA)
The U.S. Food and Drug Administration (FDA) is a pivotal regulatory agency under the Department of Health and Human Services (HHS), responsible for safeguarding public health by ensuring the safety, efficacy, and security of drugs, biologics, medical devices, food, cosmetics, and tobacco products. Established in 1906, the FDA has evolved through significant legislative milestones, such as the Federal Food, Drug, and Cosmetic Act of 1938, expanding its regulatory scope. The agency operates through various centers, including the Center for Drug Evaluation and Research (CDER), the Center for Biologics Evaluation and Research (CBER), and the Center for Devices and Radiological Health (CDRH), each tasked with specific regulatory functions. The FDA's responsibilities encompass drug approval, food safety, medical device regulation, and emergency public health responses, exemplified by its role in the COVID-19 pandemic. Despite facing challenges like balancing regulatory rigor with innovation, transparency concerns, and global supply chain complexities, the FDA remains a global leader in regulatory science. Looking forward, the FDA aims to adapt to technological advances, enhance global collaboration, and ensure equitable access to safe and effective medical products, thereby continuing its crucial role in public health protection.
  • 1.2K
  • 31 Oct 2024
Topic Review
A Multifactorial Approach for Sarcopenia Assessment
Sarcopenia refers to a progressive and generalized weakness of skeletal muscle as individuals age. Sarcopenia usually occurs after the age of 60 years and is associated with a persistent decline in muscle strength, function, and quality. A comparison of the risk factors associated with sarcopenia based on the European Working Group on Sarcopenia (1 and 2) in Older People, the Asian Working Group for Sarcopenia (1 and 2), the International Working Group on Sarcopenia, and the Foundation for the National Institutes of Health revealed no consistent patterns. Accordingly, the identification of a single risk factor for sarcopenia is unpredictable due to its “multifactorial” pathogenesis, with the involvement of a multitude of factors.
  • 1.1K
  • 29 Dec 2021
Topic Review
Essential Oils from Lamiaceae Family
Essential oils from different plant species were found to contain different compounds exhibiting anti-inflammatory effects with the potential to be a valid alternative to conventional chemotherapy that is limited in long-term use due to its serious side effects.
  • 1.1K
  • 29 Mar 2022
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