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Topic Review
Work-Related Burnout among Corporate Employees
Work is an essential part of our daily life. It has been estimated that on average, full-time workers in OECD countries spend about 37% of their time working in a normal day.  Burnout is classified as an occupational phenomenon, not as a medical condition, in the 11th version of the International Classification of Diseases (ICD-11). It is defined as: ”a syndrome conceptualized as resulting from chronic workplace stress that has not been successfully managed”.
  • 1.1K
  • 27 Jan 2022
Topic Review
Energy Emissions Reduction in South African National Parks
South African National Parks (SANParks) aimed to contribute to national targets by reducing their fossil-fuel-generated energy consumption by 2% per year until achieving carbon neutrality. SANParks achieved 1% year-on-year energy emissions reduction through its renewable base; however, an ambitious target of 8% would be appropriate for a 1.5 °C future based on the energy scenario planning.
  • 1.1K
  • 14 Feb 2022
Topic Review
High Altitude Cerebral Edema Management
High altitude illness in its most severe form can lead to high altitude cerebral edema (HACE). The strategies have focused on prevention with graduated ascents, pharmacologic prophylaxis, and descent at first signs of symptoms. Little is understood regarding treatment with steroids and oxygenation being commonly utilized. Pre-clinical studies with turmeric derivatives have offered promise due to its anti-inflammatory and antioxidant properties, but they warrant validation clinically. 
  • 1.1K
  • 25 Mar 2022
Topic Review
Lessons from Global Spread of Conservation Agriculture
Since 2008/2009, Conservation Agriculture (CA) cropland area has been expanding globally at an annual rate of more than 10 M ha per year. In 2015/2016, the total CA cropland area was 180.4 M ha, corresponding to 12.5% of global cropland area. In 2018/2019, the total cropland area was 205.4 M ha, corresponding to 14.7% of global cropland area. The spread of CA has been expanding in Asia, Africa, and Europe in recent years because farmers are becoming better organized in working together and networking. More attention and resources are being allocated by stakeholders towards supporting farmers to adopt CA and in generating new knowledge to improve their performance.
  • 1.1K
  • 15 Apr 2022
Topic Review
Tumor Microenvironment of Pancreatic Ductal Adenocarcinoma
Pancreatic cancer has a complex tumor microenvironment which engages in extensive crosstalk between cancer cells, cancer-associated fibroblasts, and immune cells. Many of these interactions contribute to tumor resistance to anti-cancer therapies. Using targeted drugs to disrupt interactions between these cells which can support cancer cell growth, invasion, and immune suppression has become an important area of exploration in the pancreatic cancer field.  Pancreatic ductal adenocarcinoma (PDAC) is the most common histology of pancreatic cancer, representing >85% of all pancreatic cancer diagnoses.
  • 1.1K
  • 08 Sep 2022
Topic Review
Ground Level Ozone
Ground level ozone (O3), also known as tropospheric ozone, is a trace gas of the troposphere (the lowest level of the Earth's atmosphere), with an average concentration of 20–30 parts per billion by volume (ppbv), with close to 100 ppbv in polluted areas. Ozone is also an important constituent of the stratosphere, where the ozone layer exists which is located between 10 and 50 kilometers above the Earth's surface. The troposphere extends from the ground up to a variable height of approximately 14 kilometers above sea level. Ozone is least concentrated in the ground layer (or planetary boundary layer) of the troposphere. Ground level or tropospheric ozone is created by chemical reactions between oxides of nitrogen (NOx gases) and volatile organic compounds (VOCs). The combination of these chemicals in the presence of sunlight form ozone. Its concentration increases as height above sea level increases, with a maximum concentration at the tropopause. About 90% of total ozone in the atmosphere is in the stratosphere, and 10% is in the troposphere. Although tropospheric ozone is less concentrated than stratospheric ozone, it is of concern because of its health effects. Ozone in the troposphere is considered a greenhouse gas, and may contribute to global warming. Photochemical and chemical reactions involving ozone drive many of the chemical processes that occur in the troposphere by day and by night. At abnormally high concentrations (the largest source being emissions from combustion of fossil fuels), it is a pollutant, and a constituent of smog. Its levels have increased significantly since the industrial revolution, as NOx gasses and VOCs are some of the byproducts of combustion. With more heat and sunlight in the summer months, more ozone is formed which is why regions often experience higher levels of pollution in the summer months. Although the same molecule, ground level ozone can be harmful to our health, unlike stratospheric ozone that protects the earth from excess UV radiation. Photolysis of ozone occurs at wavelengths below approximately 310–320 nanometres. This reaction initiates the chain of chemical reactions that remove carbon monoxide, methane, and other hydrocarbons from the atmosphere via oxidation. Therefore, the concentration of tropospheric ozone affects how long these compounds remain in the air. If the oxidation of carbon monoxide or methane occur in the presence of nitrogen monoxide (NO), this chain of reactions has a net product of ozone added to the system.
  • 1.1K
  • 28 Sep 2022
Topic Review
DASH7 Alliance
The DASH7 Alliance (D7A) is a group of companies and universities managing the evolution of the Dash7 Alliance protocol. The goal of the group is to create a complete interoperable RF technology to exchange data for wireless sensor networks and devices at a block scale (300m–1 km). Initially created with the participation of the US DoD and Lockheed Martin in 2009, the group evolved from RFID military needs (ISO-18000-7 support group role), to an industrial generic requirement. The Dash7 Alliance continued to forge an extensive experience in high reliability 433 MHz networks and extended it to 868/915 MHz. Unlike other protocols, Dash7 Alliance published layered based protocols to ensure interoperability up to the file exchange layers. A complete Open Source implementation, OSS-7, as well as industrial implementations enabled to create a certification lab and organize regular plugfest. The DASH7 Alliance was a privately held, 501(c)3 not-for-profit trade association founded in February 2009 and headquartered in San Ramon, California. Since 2015, it is a European NGO based in Brussels, Belgium.
  • 1.1K
  • 29 Sep 2022
Topic Review
Soyuz 4
Soyuz 4 (Russian: Союз 4, Union 4) was launched on 14 January 1969, carrying cosmonaut Vladimir Shatalov on his first flight. The aim of the mission was to dock with Soyuz 5, transfer two crew members from that spacecraft, and return to Earth. The previous Soyuz flight (Soyuz 3) was also a docking attempt but failed for various reasons. The radio call sign of the crew was Amur, while Soyuz 5 was Baikal. This referred to the trans-Siberian railway project called the Baikal-Amur Mainline, which was in development at the time.
  • 1.1K
  • 03 Nov 2022
Topic Review
G-Quadruplex Structures in Plants
G-quadruplex (G4) oligonucleotides are higher-order DNA and RNA secondary structures of enormous relevance due to their implication in several biological processes and pathological states in different organisms.  Plants offer a cornucopia of phytocompounds that, in many cases, are effective in binding and modulating the thermal stability of G4s and, on the other hand, contain almost unexplored G4 motifs in their genome that could inspire new biotechnological strategies.
  • 1.1K
  • 10 Nov 2022
Topic Review
Systems Designs of Phase Change Materials
The development of Phase Change Materials (PCMs) applications and products is closely related to the market penetration of the renewable energy technologies. With the initial aim of matching the phase shift between resource availability and demand in solar energy systems, the range of PCM applications expanded rapidly, entering economic sectors where some form of passive thermal regulation was required. 
  • 1.1K
  • 09 Dec 2022
Topic Review
Carbon Quantum Dots Optical
Carbon quantum dots are the materials of a new era with astonishing properties such as high photoluminescence, chemical tuneability and high biocompatibility.
  • 1.1K
  • 22 Mar 2023
Topic Review
Artificial Intelligence in Microgrid Control and Safety
Cyber attacks in microgrid systems not only cause issues with data integrity and confidentiality, but cause huge economic losses. Communication of sensor and operational data between each node is essential to attain the efficient operation of microgrid systems. Therefore, monitoring and analyzing the data continuously plays a major role in attaining data integrity. This becomes challenging when the attack is made at the device level rather than the network level. In this scenario, the basic network-level security used in the classical CPS fails to identify the attacks.  Artificial Intelligence (AI) can detect and mitigate cyber attacks.
  • 1.1K
  • 07 Jul 2023
Topic Review
AI-Based Surface Roughness Prediction for Additively Manufactured Components
Additive manufacturing has gained significant popularity from a manufacturing perspective due to its potential for improving production efficiency. However, ensuring consistent product quality within predetermined equipment, cost, and time constraints remains a persistent challenge. Surface roughness, a crucial quality parameter, presents difficulties in meeting the required standards, posing significant challenges in industries such as automotive, aerospace, medical devices, energy, optics, and electronics manufacturing, where surface quality directly impacts performance and functionality. Artificial intelligence (AI) is one of the methods used by researchers to predict the surface quality of additively fabricated parts. 
  • 1.1K
  • 23 Oct 2023
Topic Review
Eukaryotic DNA Polymerases
DNA polymerases constitute a versatile group of enzymes that not only perform the essential task of genome duplication but also participate in various genome maintenance pathways, such as base and nucleotide excision repair, non-homologous end-joining, homologous recombination, and translesion synthesis. Polymerases catalyze DNA synthesis via the stepwise addition of deoxynucleoside monophosphates to the 3′ primer end in a partially double-stranded DNA.
  • 1.1K
  • 04 Jan 2024
Topic Review
Non-Renewable Energy Efficiency and Renewable Energy
Policymakers and environmental scientists have proposed numerous measures toward achieving a sustainable environment. Some of these measures include the efficient use of energy and a scaling up of clean energy transition.
  • 1.1K
  • 18 Jan 2024
Topic Review
Environmental Impact of Electricity Generation Technologies
The transformation of the energy sector, based on the development of low-carbon technologies, is essential to achieve climate neutrality. The Life Cycle Assessment (LCA) is a powerful methodology for assessing the environmental impact of energy technologies, which proves to be a useful tool for policy makers. 
  • 1.1K
  • 20 Feb 2024
Topic Review
The Digestive Vacuole of the Malaria Parasite
The malaria parasite resides within erythrocytes during one stage of its life cycle. During this intraerythrocytic period, the parasite ingests the erythrocyte cytoplasm and digests approximately two-thirds of the host cell hemoglobin. This digestion occurs within a lysosome-like organelle called the digestive vacuole. Several proteases are localized to the digestive vacuole and these proteases sequentially breakdown hemoglobin into small peptides, dipeptides, and amino acids. The peptides are exported into the host cytoplasm via the chloroquine-resistance transporter and an amino acid transporter that has also been identified on the digestive vacuole membrane. The environment of the digestive vacuole also provides appropriate conditions for the biocrystallization of toxic heme into non-toxic hemozoin by a poorly understood process. Hemozoin formation is an attribute of Plasmodium and Haemoproteus and is not exhibited by other intraerythrocytic protozoan parasites. The efficient degradation of hemoglobin and detoxification of heme likely plays a major role in the high level of replication exhibited by malaria parasites within erythrocytes. Unique features of the digestive vacuole and the critical importance of nutrient acquisition provide therapeutic targets for the treatment of malaria.
  • 1.1K
  • 29 Feb 2024
Topic Review Peer Reviewed
Barriers and Facilitators to Binge-Watching Using the Theoretical Domains Framework
Using the Theoretical Domains Framework (TDF), this rapid review coded the barriers and facilitators to binge-watching and identified corresponding behaviour change techniques (BCTs) for intervention purposes. Twenty-nine studies reporting influences on binge-watching fulfilled the inclusion criteria and passed quality appraisal checks. Data were extracted and coded accordingly, as informed by the TDF. Findings indicate that most facilitators focused on the goals of binge-watching, such as escapism, and the social influences, such as companionship, while most barriers related to behavioural regulation, such as self-control and self-regulation. BCTs included ‘Goal setting (outcome)’, ‘Social comparison’, and ‘Self-monitoring of behaviour’. Results suggest intervention strategies targeting facilitators to binge-watching by incorporating the identified BCTs may succeed in inhibiting binge-watching behaviours. However, accounting for the intensity of binge-watching was not an objective of the present review; therefore, future research should take into account the varying levels of engagement in binge-watching when developing interventions.
  • 1.1K
  • 13 Aug 2024
Topic Review
Beginning of Meiosis in Mammalian Female Germ Cells
Meiosis is the unique division of germ cells resulting in the recombination of the maternal and paternal genomes and the production of haploid gametes. In mammals, it begins during the fetal life in females and during puberty in males. In both cases, entering meiosis requires a timely switch from the mitotic to the meiotic cell cycle and the transition from a potential pluripotent status to meiotic differentiation. Revealing the molecular mechanisms underlying these interrelated processes represents the essence in understanding the beginning of meiosis. Meiosis facilitates diversity across individuals and acts as a fundamental driver of evolution. Major differences between sexes and among species complicate the understanding of how meiosis begins.
  • 1.1K
  • 30 Oct 2022
Topic Review
Location-Aware Wi-Fi Authentication Scheme
Advanced wireless technology in Internet of Things (IoT) devices is increasing and facing various security threats. The authentication of IoT devices is the first line of defense for the wireless network. Especially in a Wi-Fi network, the existing authentication methods mainly use a password or digital certificate, these methods are inconvenient to manage due to certificate issuance or prone to be attacked because passwords are easily cracked. A location-aware authentication scheme was proposed, using smart contracts to ensure that IoT devices can securely perform Wi-Fi network authentication. The scheme adopts the concept of secondary authentication and consists of two phases: the registration phase, which is mainly designed to complete the generation of the public and private keys, and to link the device information with its related device information; the authentication phase, which is mainly designed to determine whether the requesting device is within a legal location range. The smart contract to ensure the credibility and irreparability of the authentication process. Analysis of the attack model and the attacks at different stages proves that this certification scheme is assured, and the simulation results show that the overhead introduced by this scheme is acceptable, this scheme can provide greater security for the Wi-Fi authentication of IoT devices.
  • 1.1K
  • 01 Nov 2020
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