Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Bulk and Microfluidic-Based pH Sensors
The determination of pH is of paramount importance in environmental, pharmaceutical, and medicinal sciences, etc., for accurate controlling, monitoring, and adjusting whole processes on microscale and macroscale. Therefore, the pH measurements have drawn continuous efforts from a great deal of research. The bulk pH determination can tackle part of the demands from laboratories and industrial applications.
  • 1.2K
  • 01 Dec 2022
Topic Review
Click Fraud
Click fraud is a type of fraud that occurs on the Internet in pay-per-click (PPC) online advertising. In this type of advertising, the owners of websites that post the ads are paid an amount of money determined by how many visitors to the sites click on the ads. Fraud occurs when a person, automated script or computer program imitates a legitimate user of a web browser, clicking on such an ad without having an actual interest in the target of the ad's link. Click fraud is the subject of some controversy and increasing litigation due to the advertising networks being a key beneficiary of the fraud. Media entrepreneur and journalist John Battelle describes click fraud as the intentionally malicious, "decidedly black hat" practice of publishers illegitimately gaming paid search advertising by employing robots or low-wage workers to repeatedly click on each AdSense ad on their sites, thereby generating money to be paid by the advertiser to the publisher and to Google.
  • 1.2K
  • 10 Nov 2022
Topic Review
American International Health Alliance
American International Health Alliance (AIHA) is a nonprofit organisation aiming for assisting the global health. The organisation has managed more than 175 partnerships and project across the globe. In 2012, AIHA obtained the support of President's Emergency Plan for AIDS Relief [PEPFAR] project  to strengthen the blood service in Central Asia, Ukraine, and Cambodia. Due to its structure based on the programmatic modal and dynamic condition, this organisation is suitable to assist the community or worldwide countries which have limited resources, and it is beneficial for sustainable evolution. AIHA is contributing to improve the worldwide health conditions. This organisation has been associated and largely contributed in the HIV-related area since 2000.
  • 1.2K
  • 14 Nov 2022
Topic Review
Robitussin
Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The term encompasses a broad array of drugs, including analgesics, antihistamines and decongestants, among many others. It also includes drugs which are marketed as cough suppressants or antitussives, but their effectiveness in reducing cough symptoms is unclear or minimal. While they have been used by 10% of American children in any given week, they are not recommended in Canada or the United States in children six years or younger because of lack of evidence showing effect and concerns of harm. One version with codeine, guaifenesin, and pseudoephedrine was the 213th most commonly prescribed medication in 2017, in the United States, with more than two million prescriptions.
  • 1.2K
  • 25 Nov 2022
Topic Review
Anthocyanin Delivery Systems
Anthocyanins (ACNs) are polyphenolic, water-soluble pigments, and phytochemicals, which in recent years, have garnered the interest of consumers, researchers, and industries for their various potential preventative and/or therapeutic health benefits and applications in the food industry. ACN-based processed foods have emerged as functional foods with significant therapeutic potential against various health conditions. ACNs can be stabilized by embedding them in nanocarrier systems to produce microcapsules, acylating their reactive groups, or forming copigments with other macromolecules
  • 1.2K
  • 05 Dec 2022
Topic Review
Sympathetic Nerve in Chronic Pain-Associated Cardiovascular Disease
Chronic pain affects many people world-wide, and this number is continuously increasing. There is a clear link between chronic pain and the development of cardiovascular disease through activation of the sympathetic nervous system.
  • 1.2K
  • 13 Apr 2023
Topic Review
Sobrerol
Respiratory tract infections (RTIs) are usually characterized by mucus hypersecretion. This condition may worsen and prolong symptoms and signs. For this reason, reducing mucus production and improving mucus removal represent relevant aspects of managing patients with RTIs. In this regard, mucoactive drugs may be effective. Mucoactive agents constitute a large class of compounds characterized by different mechanisms of action. Sobrerol is a monoterpene able to fluidify mucus, increase mucociliary clearance, and exert antioxidant activity. Sobrerol is available in various formulations (granules, syrup, nebulized, and suppository). Sobrerol has been on the market for over 50 years.
  • 1.2K
  • 18 Jul 2023
Topic Review
Textile Electrodes for Wearable Biopotential Signal Monitoring
The technology of wearable medical equipment has advanced to the point where it is now possible to monitor the electrocardiogram and electromyogram comfortably at home. The transition from wet Ag/AgCl electrodes to various types of gel-free dry electrodes has made it possible to continuously and accurately monitor the biopotential signals. Fabrics or textiles, which were once meant to protect the human body, have undergone significant development and are now employed as intelligent textile materials for healthcare monitoring. The conductive textile electrodes provide the benefit of being breathable and comfortable.
  • 1.2K
  • 11 Aug 2023
Topic Review
Sustainable Interior Design Practices in Jordan
Interior designers play a pivotal role in shaping the built environment and catalyzing positive change through the adoption of sustainable design practices. Within the context of Jordan, a nation experiencing rapid urbanization and robust economic development, the integration of sustainable principles into interior design emerges as a critical imperative.
  • 1.2K
  • 16 Oct 2023
Topic Review
Autism Spectrum Disorder and Screen Time
There is growing evidence that prevalence rates of autism spectrum disorder (ASD) are increasing. A number of factors appear to contribute to this increase, including excessive screen time. Screen time seems to be linked to the severity of the symptoms of ASD. 
  • 1.2K
  • 26 Feb 2024
Topic Review
Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer in both adult and pediatric populations, occurring more commonly in women at ages 50-59. PTC is characterized by the presence of cells arranged into papillae, presenting clear or ground-glass nuclei. It is further subdivided based on histological variants, such as the classic (CVPTC), follicular (FVPTC), solid (SVPTC), and diffuse sclerosing (DSVPTC) variants.
  • 1.2K
  • 18 Nov 2020
Topic Review
TRIM
The tripartite motif (TRIM) gene family is a large group of E3 ubiquitin ligase proteins that can also have proteasome-independent functions. TRIM/RBCC are a large family of proteins that include more than 80 proteins, most of which act as E3 ligases and catalyze the direct transfer of Ubiquitin, SUMO and ISG15 on specific protein substrates. They are involved in oncogenesis processes and in cellular immunity.
  • 1.2K
  • 19 May 2022
Topic Review
Land Cover Change Detection
Land cover patterns in sub-Saharan Africa are rapidly changing. This study aims to quantify the land cover change and to identify its major determinants by using the Drivers, Pressures, State, Impact, Responses (DPSIR) framework in the Ethiopian Gozamin District over a period of 32 years (1986 to 2018). Satellite images of Landsat 5 (1986), Landsat 7 (2003), and Sentinel-2 (2018) and a supervised image classification methodology were used to assess the dynamics of land cover change. Land cover maps of the three dates, focus group discussions (FGDs), interviews, and farmers’ lived experiences through a household survey were applied to identify the factors for changes based on the DPSIR framework. Results of the investigations revealed that during the last three decades the study area has undergone an extensive land cover change, primarily a shift from cropland and grassland into forests and built-up areas. Thus, quantitative land cover change detection between 1986 and 2018 revealed that cropland, grassland, and bare areas declined by 10.53%, 5.7%, and 2.49%. Forest, built-up, shrub/scattered vegetation, and water bodies expanded by 13.47%, 4.02%, 0.98%, and 0.25%. Household surveys and focus group discussions (FGDs) identified the population growth, the rural land tenure system, the overuse of land, the climate change, and the scarcity of grazing land as drivers of these land cover changes. Major impacts were rural to urban migration, population size change, scarcity of land, and decline in land productivity. The outputs from this study could be used to assure sustainability in resource utilization, proper land use planning, and proper decision-making by the concerned government authorities.
  • 1.2K
  • 27 Oct 2020
Topic Review
Micro RNA in Osteoporosis
Osteoporosis is a major concern worldwide and can be attributed to an imbalance between osteoblastic bone formation and osteoclastic bone resorption due to the natural aging process. Heritable factors account for 60–80% of optimal bone mineralization; however, the finer details of pathogenesis remain to be elucidated. Micro RNA (miRNA) and long-non-coding RNA (lncRNA) are two targets that have recently come into the spotlight due to their ability to control gene expression at the post-transcriptional level and provide epigenetic modification. miRNAs are a class of non-coding RNAs that are approximately 18–25 nucleotides long. It is thought that up to 60% of human protein-coding genes may be regulated by miRNAs. They have been found to regulate gene expression that controls osteoblast-dependent bone formation and osteoclast-related bone remodeling. lncRNAs are highly structured RNA transcripts longer than 200 nucleotides that do not translate into proteins. They have very complex secondary and tertiary structures and the same degradation processes as messenger RNAs. The fact that they have a rapid turnover is due to their sponge function in binding the miRNAs that lead to a degradation of the lncRNA itself. They can act as signaling, decoy, and framework molecules, or as primers. Current evidence suggests that lncRNAs can act as chromatin and transcriptional as well as post-transcriptional regulators. With regards to osteoporosis, lncRNA is thought to be involved in the proliferation, apoptosis, and inflammatory response of the bone. This review, which is based on a systematic appraisal of the current literature, provides current molecular and genetic opinions on the roles of miRNAs and lncRNAs in osteoporosis. Further research into the epigenetic modification and the regulatory roles of these molecules will bring us closer to potential disease-modifying treatment for osteoporosis.
  • 1.2K
  • 16 Sep 2023
Topic Review
PEX1 Gene
peroxisomal biogenesis factor 1
  • 1.2K
  • 25 Dec 2020
Topic Review
Health Benefit Components in Grain
Cereal grains provide half of the calories consumed by humans. In addition, they contain important compounds beneficial for health. During the last years, a broad spectrum of new cereal grain-derived products for dietary purposes emerged on the global food market. Special breeding programs aimed at cultivars utilizable for these new products have been launched for both the main sources of staple foods (such as rice, wheat, and maize) and other cereal crops (oat, barley, sorghum, millet, etc.). The breeding paradigm has been switched from traditional grain quality indicators (for example, high breadmaking quality and protein content for common wheat or content of protein, lysine, and starch for barley and oat) to more specialized ones (high content of bioactive compounds, vitamins, dietary fibers, and oils, etc.).
  • 1.2K
  • 11 Jan 2021
Topic Review
Adoptive Immunotherapy beyond CAR T-Cells
The aging of the world population leads to a constant increase of cancer-related morbidity and mortality. Treatment of late-stage tumors has become a significant burden on the healthcare system globally. Adoptive cell immunotherapy is supposed to prolong life with cancer and ideally cure cancer after a single infusion of the cell product. Arguably, the most impressive clinical therapy in this field is based on chimeric antigen receptor (CAR) T-cells capable of curing up to 25–50% of previously incurable patients with B-cell malignancies. Diverse cell therapies are already efficiently used in clinics for cancer treatment (such as tumor infiltrating lymphocytes, transgenic αβ T-cells) and several novel promising cell therapies are in development (such as CAR M-cells, transgenic γδ T-cells, CAR NK-cells). Here, we summarize the recent literature data with the focus on T-cell receptor-based therapies and overview the most advanced systems for manufacturing of clinical grade cell products. 
  • 1.2K
  • 22 Dec 2021
Topic Review
SARS-CoV-2 Genomics
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a great threat to public health, being a causative pathogen of a deadly coronavirus disease (COVID-19). It has spread to more than 200 countries and infected millions of individuals globally. Although SARS-CoV-2 has structural/genomic similarities with the previously reported SARS-CoV and MERS-CoV, the specific mutations in its genome make it a novel virus. Available therapeutic strategies failed to control this virus. Despite strict standard operating procedures (SOPs), SARS-CoV-2 has spread globally and it is mutating gradually as well.
  • 1.2K
  • 02 Mar 2021
Topic Review
Oxidative Stress/Inflammation in SARS-CoV-2 Infection
Oxidative stress (OS) has a potential key role in the COVID-19 pathogenesis by triggering the NOD-like receptor family pyrin domain containing 3 inflammasome and nuclear factor-kB (NF-kB). While exposure to many pro-oxidants usually induces nuclear factor erythroid 2 p45-related factor2 (NRF2) activation and upregulation of antioxidant related elements expression, respiratory viral infections often inhibit NRF2 and/or activate NF-kB pathways, resulting in inflammation and oxidative injury. Hence, the use of radical scavengers like N-acetylcysteine and vitamin C, as well as of steroids and inflammasome inhibitors, has been proposed. The NRF2 pathway has been shown to be suppressed in severe SARS-CoV-2 patients. Pharmacological NRF2 inducers have been reported to inhibit SARS-CoV-2 replication, the inflammatory response, and transmembrane protease serine 2 activation, which for the entry of SARS-CoV-2 into the host cells through the angiotensin converting enzyme 2 receptor.
  • 1.2K
  • 18 Mar 2021
Topic Review
Virtual Reality in the Rehabilitation
Over the past two decades, virtual reality technology (VRT)-based rehabilitation has been increasingly examined and applied to assist patient recovery in the physical and cognitive domains. The advantages of the use of VRT in the neurorehabilitation field consist of the possibility of training an impaired function as a way to stimulate neuron reorganization (to maximize motor learning and neuroplasticity) and restoring and regaining functions and abilities by interacting with a safe and nonthreatening yet realistic virtual reality environment (VRE). Furthermore, VREs can be tailored to patient needs and provide personalized feedback on performance. VREs may also support cognitive training and increases patient motivation and enjoyment. Despite these potential advantages, there are inconclusive data about the usefulness of VRT in neurorehabilitation settings, and some issues on feasibility and safety remain to be ascertained for some neurological populations.
  • 1.2K
  • 07 May 2021
  • Page
  • of
  • 2729
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback