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Topic Review
Coram Nobis
The writ of coram nobis (also known as writ of error coram nobis, writ of coram vobis, or writ of error coram vobis) is a legal order allowing a court to correct its original judgment upon discovery of a fundamental error that did not appear in the records of the original judgment’s proceedings and would have prevented the judgment from being pronounced. The term "coram nobis" is Latin for "before us" and the meaning of its full form, quae coram nobis resident, is "which [things] remain in our presence". The writ of coram nobis originated in the English court of common law in the English legal system during the sixteenth century. The writ of coram nobis still exists today in a few courts in the United States. In 1907, the writ became obsolete in England and replaced by other means of correcting errors; however, the writ survives in the United States in various forms in the federal courts, in fifteen state courts, and the District of Columbia courts. For those courts with the authority to issue a writ of coram nobis, the rules and guidelines differ – sometimes significantly. Each state is free to operate its own coram nobis procedures independent of other state courts as well as the federal court system. In other words, the criteria required to issue the writ in one state (or federal) court system are different from the criteria required to issue the writ in a different court system. A writ can be granted only by the court where the original judgment was entered, so those seeking to correct a judgment must understand the criteria required for that specific court.
  • 1.4K
  • 14 Oct 2022
Topic Review
Co-operation (Evolution)
In evolution, co-operation is the process where groups of organisms work or act together for common or mutual benefits. It is commonly defined as any adaptation that has evolved, at least in part, to increase the reproductive success of the actor's social partners. For example, territorial choruses by male lions discourage intruders and are likely to benefit all contributors. This process contrasts with intragroup competition where individuals work against each other for selfish reasons. Cooperation exists not only in humans but in other animals as well. The diversity of taxa that exhibits cooperation is quite large, ranging from zebra herds to pied babblers to African elephants. Many animal and plant species cooperate with both members of their own species and with members of other species.
  • 1.4K
  • 23 Oct 2022
Biography
Dagmar Schipanski
Dagmar Elisabeth Schipanski (born 3 September 1943) is a German physicist, academic, and politician from the State of Thuringia. Best known for 1999 nomination as President of Germany by the conservative Christian Democratic Union (CDU) and its sister party, the Christian Social Union of Bavaria (CSU), Schipanski has held a variety of political and academic roles her during four-decade-long care
  • 1.4K
  • 15 Nov 2022
Topic Review
Ketoprofen Lysine Salt as Pharmacological Treatment for SARS-CoV-2
COVID-19 is an infective disease resulting in widespread respiratory and non-respiratory symptoms prompted by SARS-CoV-2 infection. Interaction between SARS-CoV-2 and host cell receptors prompts activation of pro-inflammatory pathways which are involved in epithelial and endothelial damage mechanisms even after viral clearance. Since inflammation has been recognized as a critical step in COVID-19, anti-inflammatory therapies, including both steroids and non-steroids as well as cytokine inhibitors, have been proposed. Early treatment of COVID-19 has the potential to affect the clinical course of the disease regardless of underlying comorbid conditions. Non-steroidal anti-inflammatory drugs (NSAIDs), which are widely used for symptomatic relief of upper airway infections, became the mainstay of early phase treatment of COVID-19.
  • 1.4K
  • 11 Jan 2023
Topic Review
Formation of Oxidative Compounds in Fish Protein Hydrolysates
There is a significant potential to increase the sustainability of the fishing and aquaculture industries through the maximization of the processing of byproducts. Enzymatic hydrolysis provides an opportunity to valorize downstream fish industry byproducts for the production of protein hydrolysates (FPH) as a source of bioactive peptides (BAP) with health benefits. Deteriorative oxidative reactions may occur during the enzymatic hydrolysis of byproducts, influencing the safety or bioactivities of the end product. Lipid oxidation, autolysis mediated by endogenous enzymes in viscera, protein degradation, and formation of low-molecular-weight metabolites are the main reactions that are expected to occur during hydrolysis and need to be controlled. 
  • 1.4K
  • 10 Mar 2023
Topic Review
Consumer Behavior, Sunscreens, and Tools for Photoprotection
Sunscreens and photoprotection tools along with consumer habits and behaviors, can mitigate the skin damage caused by excessive solar radiation. For example, protecting oneself in the shade, avoiding inadequate sun exposure at times of higher incidence of UVB radiation (between 10:00 a.m. and 4:00 p.m.), wearing clothes with sun protection factors, applying sunscreens at the correct amounts and intervals, and wearing glasses with anti-UVA and UVB lenses are effective measures for protecting an individual.
  • 1.4K
  • 03 Apr 2023
Topic Review
Environmental Valuation Research
Environmental valuation (EV) research has advanced significantly as a method of assigning value to environmental goods, many of which lack readily discernible market values. The term “environmental valuation” describes a number of methods for putting monetary values on environmental effects, particularly non-market effects. There has been a continuous increase in the number of publications on the topic. According to searches via the Scopus and Web of Science (WoS) databases, the phrase “environmental valuation” first occurred in 1987.
  • 1.4K
  • 14 Apr 2023
Topic Review
Soluble Guanylyl Cyclase Activators
The guanylyl cyclase (sGC) is heme-containing enzyme, which causes an increase in the level of cyclic 3′-5′-guanosine monophosphate (cGMP) in smooth muscle and subsequent vascular relaxation.
  • 1.4K
  • 10 May 2023
Topic Review
Application of Probiotics for Acne Vulgaris Topical Therapies
The skin microbiome is an essential barrier for preventing the invasion of pathogens and regulating the immune responses. When this barrier is disrupted, several dermatoses, including acne vulgaris, may arise. Probiotics have proven to be an alternative to the use of antibiotics, often associated with undesirable effects, in the treatment and prevention of dermatological disorders such as acne. 
  • 1.4K
  • 30 May 2023
Topic Review
Human Emotion Recognition System
Emotion recognition becomes an important aspect in the development of human-machine interaction (HMI) systems. Positive emotions impact our lives positively, whereas negative emotions may cause a reduction in productivity. Emotionally intelligent systems such as chatbots and artificially intelligent assistant modules help make our daily life routines effortless. Moreover, a system which is capable of assessing the human emotional state would be very helpful to assess the mental state of a person.
  • 1.4K
  • 28 Jun 2023
Topic Review
Heterogeneous Catalysts Used in Hydrothermal Gasification
Supercritical water gasification has emerged as a promising technology to sustainably convert waste residues into clean gaseous fuels rich in combustible gases such as hydrogen and methane. The composition and yield of gases from hydrothermal gasification depend on process conditions such as temperature, pressure, reaction time, feedstock concentration, and reactor geometry. However, catalysts also play a vital role in enhancing the gasification reactions and selectively altering the composition of gas products. Catalysts can also enhance hydrothermal reforming and cracking of biomass to achieve desired gas yields at moderate temperatures, thereby reducing the energy input of the hydrothermal gasification process. 
  • 1.4K
  • 04 Jul 2023
Topic Review
Semi-Supervised Image Stitching from Unstructured Camera Arrays
Image stitching involves combining multiple images of the same scene captured from different viewpoints into a single image with an expanded field of view. While this technique has various applications in computer vision, traditional methods rely on the successive stitching of image pairs taken from multiple cameras. While this approach is effective for organized camera arrays, it can pose challenges for unstructured ones, especially when handling scene overlaps.
  • 1.4K
  • 14 Dec 2023
Topic Review
Photovoltaic Integration with the Saudi Electricity Grid
Due to uncertain photovoltaic (PV) power generation, analyzing the voltage stability of transmission networks with a large PV plant is challenging. The stability of PV output power is a critical factor in establishing PV penetration levels in active transmission networks when assessing loading capabilities. 
  • 1.4K
  • 29 Feb 2024
Topic Review
Energy Intake in CKD-MBD
This study is aimed to review current knowledge about the influence of energy intake on mineral metabolism focussing on four aspects of major interest for the chronic kidney disease-metabolic bone disease (CKD-MBD) patient: (a) phosphate (P) handling, (b) fibroblast growth factor 23 (FGF23) and calcitriol synthesis and secretion, (c) metabolic bone disease, and (d) vascular calcification (VC). High caloric intake promotes P retention, while caloric restriction decreases plasma P concentrations. A direct correlation between energy intake and FGF23 has been shown in animals and humans while plasma calcitriol concentrations are inversely proportional to caloric intake. The effect of energy intake on bone is controversial. High caloric intake has been reported to increase bone mass, but the associated changes in adipokines and cytokines may as well be deleterious for bone. Low caloric intake tends to reduce bone mass but also may provide indirect beneficial effects on bone. Finally, while VC has been shown to be exacerbated by diets with high energy content, the opposite has not been demonstrated with low calorie intake. In conclusion, although prospective studies in humans are needed, when planning caloric intake for a CKD-MBD patient, it is important to take into consideration the associated changes in mineral metabolism.
  • 1.4K
  • 11 Jan 2021
Topic Review
Fluidized Bed Reactors
Fluidized gasification reactors can be used to produce hydrogen. They are operated in three modes including bubbling, circulating, and dual beds, as depicted inC. In a bubbling fluidized bed (BFB), the fuel is introduced from the bottom or side of the bed. The bed starts bubbling when the velocity of gasification agent is beyond the minimum fluidization velocity.
  • 1.4K
  • 18 Sep 2021
Topic Review
Boron Nitride Materials
Boron nitride 2D materials are characterized by several defects which affect their optical properties. A better in-sight of the structure is achieved by theoretical calculations which have been used to investigate the boron-nitride defects and their functionalization on the atomic scale. A brief overview of the main theoretical models used to describe the defects-properties relationship is given in the present entry.
  • 1.4K
  • 26 Oct 2020
Topic Review
Micro combined heat and power
       Micro Combined Heat and Power (µCHP) systems in a DG infrastructure can reduce a building’s primary energy consumption, reduce carbon footprint, and enhance resiliency. The simultaneous production of electrical and thermal energy from a single fuel source at a high overall energy efficiency can reduce primary energy consumption while lowering greenhouse gas (GHG) emissions. A comprehensive overview of various modeling approaches adopted by international researchers is presented. The key objective is to present the state-of-the-art models and approaches while identifying opportunities for further refinement to expand the capabilities of such models for versatile applications.  
  • 1.4K
  • 27 Aug 2020
Topic Review
GALNT14
Members in the polypeptide N-acetylgalactosaminyltransferase (GALNT) family function as the initiating enzymes to catalyze mucin-type O-glycosylation of proteins, of which dysregulated expression can alter cancer cell behaviors such as de novo occurrence, proliferation, migration, metastasis and drug resistance. One of its members, GALNT14, is aberrantly expressed in multiple cancers and involved in a variety of biological functions. Moreover, the single nucleotide polymorphisms (SNPs) of GALNT14-rs9679162 has been shown to predict the therapeutic outcomes in patients with hepatocellular carcinoma as well as several other different types of gastrointestinal cancers. 
  • 1.4K
  • 29 Oct 2020
Topic Review
Cancer Immunotherapy
Cancer treatment has evolved tremendously in the last few decades. Immunotherapy has been considered to be the forth pillar in cancer treatment in addition to conventional surgery, radiotherapy, and chemotherapy. Though immunotherapy has resulted in impressive response, it is generally limited to a small subset of patients. Understanding the mechanisms of resistance toward cancer immunotherapy may shed new light to counter that resistance. In this entry, we highlighted and summarized two major hurdles (recognition and attack) of cancer elimination by the immune system. The mechanisms of failure of some available immunotherapy strategies were also described. Moreover, the significance role of immune compartment for various established cancer treatments were also elucidated . Then, the mechanisms of combinatorial treatment of various conventional cancer treatment with immunotherapy were discussed. Finally, a strategy to improve immune cancer killing by characterizing cancer immune landscape, then devising treatment based on that cancer immune landscape was put forward.
  • 1.4K
  • 21 Oct 2020
Topic Review
Single-Cell RNA Sequencing
Single-cell RNA sequencing (scRNA-seq) technology is a powerful, rapidly developing tool for characterizing individual cells and elucidating biological mechanisms at the cellular level. Cardiovascular disease is one of the major causes of death worldwide and its precise pathology remains unclear. scRNA-seq has provided many novel insights into both healthy and pathological hearts. In this review, we summarize the various scRNA-seq platforms and describe the molecular mechanisms of cardiovascular development and disease revealed by scRNA-seq analysis. We then describe the latest technological advances in scRNA-seq. Finally, we discuss how to translate basic research into clinical medicine using scRNA-seq technology.
  • 1.4K
  • 19 Nov 2020
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