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Topic Review
Salt Lake Aerosols' Chemical Composition and Health Effects
Salt Lakes, having a salt concentration higher than that of seawater and hosting unique extremophiles, are predominantly located in drought-prone zones worldwide, accumulating diverse salts and continuously emitting salt dust or aerosols. Salt Lake aerosols are produced through various processes, including lake-water spray, evaporation-induced salt crystallization, wind-driven dust emissions, microbial activities, chemical reactions, and anthropogenic influences. The primary mechanism involves the breaking of wind-driven waves at the lake surface. As the wind blows across the water, it generates waves. When these waves reach a critical size, they break and release tiny droplets into the air, which become airborne particles and form aerosols.
  • 1.4K
  • 29 Feb 2024
Topic Review Peer Reviewed
Biorefinery Based on Multiple Raw Materials and Wastes for the Production of Energy: A Proposal Tailored to Southwestern Europe
In this entry, the possibility of the implementation of a biorefinery based on multiple raw materials (from agricultural wastes, vegetable oils, etc.) is covered, pointing out the available technology to interconnect different processes so that the atom economy of the process is as high as possible, reducing the environmental impact and improving the efficiency of the energy or products obtained. For this purpose, this model is based on previous works published in the literature. The role of biorefineries is becoming more and more important in the current environmental scenario, as there is a global concern about different environmental issues such as climate change due to GHG emissions, among others. In this sense, a biorefinery presents several advantages such as the use of natural raw materials or wastes, with high atom economy values (that is, all the products are valorized and not released to the environment). As a consequence, the concept of a biorefinery perfectly fits with the Sustainable Development Goals, contributing to the sustainable growth of different regions or countries, regardless of their stage of development. The aim of this entry is the proposal of a biorefinery based on multiple raw materials, using different technologies such as transesterification to produce both biodiesel and biolubricants, steam reforming to produce hydrogen from glycerol or biogas, hydrothermal carbonization of sewage sludge to produce hydrochar, etc. As a result, these technologies have potential for the possible implementation of this biorefinery at the industrial scale, with high conversion and efficiency for most processes included in this biorefinery. However, there are some challenges like the requirement of the further technological development of certain processes. In conclusion, the proposed biorefinery offers a wide range of possibilities to enhance the production of energy and materials (hydrogen, biodiesel, biolubricants, different biofuels, hydrochar, etc.) through green technologies, being an alternative for petrol-based refineries.
  • 1.4K
  • 30 Sep 2024
Topic Review
Corynebacterium Glutamicum Mechanosensing
Corynebacterium glutamicum is a workhorse for industrial amino acid production, and the most striking feature of this bacterium is L-glutamate secretion. L-glutamate secretion is triggered by altering cell surface structures by biotin limitation, adding surfactants, penicillin, etc. Mechanosensing by MscCG-type mechanosensitive channels is the central physiological phenomenon for the L-glutamate secretion, and understanding the structural and functional diversity of MscS bacterial mechanosensitive channel superfamily will solve long-puzzling questions in Corynebacterium glutamicum.
  • 1.4K
  • 25 Feb 2021
Topic Review
AVIC UAVs
AVIC UAVs are Chinese UAVs developed by Aviation Industry Corporation of China (AVIC), some of which has entered service with Chinese military.
  • 1.4K
  • 02 Dec 2022
Topic Review
Kynurenine Pathway
Tryptophan metabolism plays an essential role in human health. In mammals, about 95% of dietary tryptophan is metabolized through the kynurenine pathway, which is associated with the development of several pathologies, including neurodegeneration. Some of the kynurenine pathway metabolites are agonists of the aryl hydrocarbon receptor involved in metabolic functions, inflammation, and carcinogenesis. 
  • 1.4K
  • 30 Nov 2023
Topic Review
Inherited Bone Marrow Failure Syndromes
Inherited bone marrow failure syndromes (IBMFS) are a group of cancer prone genetic diseases characterized by hypocellular bone marrow with impairment in one or more hematopoietic lineages. The pathogenesis of IBMFS involves mutations in several genes which encode for proteins involved in DNA repair, telomere biology and ribosome biogenesis. Unofrtunately, no pharmacological therapies have been developed for IBMFS so far and bone marrow hematopoietic stem cell transplant remains the unique option to correct bone marrow failure and prevent myeloid neoplasia.
  • 1.4K
  • 19 Nov 2020
Topic Review
Learning for Unmanned Ground Vehicles
The problem of autonomous navigation of a ground vehicle in unstructured environments is both challenging and crucial for the deployment of this type of vehicle in real-world applications. We present a review on the recent contributions in the roboticsliterature adopting learning-based methods to solve the problem of environment perception andinterpretation with the final aim of the autonomous context-aware navigation of ground vehicles inunstructured environments.
  • 1.4K
  • 29 Apr 2021
Topic Review
Neuron–Glia Interaction in ENS
The enteric nervous system (ENS) constitutes the largest part of the peripheral nervous system.
  • 1.4K
  • 19 Jan 2021
Topic Review
Grief Iconography
Is the evolving practice of online posting of photographs and images, often accompanied by emotional comments about deceased loved ones. It is frequently used to express mourning and sorrow, maintain a continuing bond with the deceased, cope with grief, pay homage to the deceased  and provide the mourner opportunities to receive empathic support from other users. Grief iconography is observable across various Social Network Sites and various cultures (see Cupit, Sapelli, & Testoni, 2021). This practice may be considered as the online evolution of past visual displays of loss and grief,  such as post-mortem photography or mourning portraits.
  • 1.4K
  • 30 Sep 2021
Topic Review
Imaging of Biofilms and Diversity of Detection Methods
Bacterial biofilms are defined as complex aggregates of bacteria that grow attached to surfaces or are associated with interfaces. Bacteria within biofilms are embedded in a self-produced extracellular matrix made of polysaccharides, nucleic acids, and proteins. It is recognized that bacterial biofilms are responsible for the majority of microbial infections that occur in the human body, and that biofilm-related infections are extremely difficult to treat. This is related with the fact that microbial cells in biofilms exhibit increased resistance levels to antibiotics in comparison with planktonic (free-floating) cells. 
  • 1.4K
  • 20 Dec 2021
Topic Review
Acyclic Nucleic Acids with Phosphodiester Linkages
The pseudo-rotational flexibility of the ribonucleotide is considerably limited due to the anomeric effect, and RNA/RNA and RNA/DNA duplexes are generally more thermally stable than DNA/DNA duplexes. The rigidity of the cyclic scaffold has been considered important for the formation of thermally stable duplexes, and the unexpectedly high thermal stability of duplexes formed with the participation of LNA oligomers could serve as an excellent justification for this point of view. However, this generalization is not consistent with the behavior of Peptide Nucleic Acids (PNA), in which the heterocyclic bases are attached to a linear peptide-like backbone, since duplexes composed of RNA or DNA and PNA strands are far more stable than RNA/RNA and DNA/DNA ones. This phenomenon may be attributed to the absence of a negative charge in the backbone, such that the absence of repulsive interactions balances the entropic cost of proper spatial organization of the flexible PNA scaffolds. Nonetheless, the widely accepted importance of the cyclic sugar components for the stability of the duplexes could be questioned. There is another perspective that can be applied to the acyclic analogs of nucleic acids that is related to the origin of life. The synthetic efforts on acyclic analogs of nucleic acids and provides information on the most interesting features of selected classes of such compounds, are here described. The selection includes the following types of analogs: Flexible (FNA), Unlocked (UNA), Glycol (GNA), Butyl (BuNA), Threoninol (TNA) and Serinol Nucleic Acids (SNA). These classes of analogs are discussed in terms of their synthetic methods, the thermal stability of their homo- and hetero-duplexes and their applicability in biological and biochemical research and nanotechnology.
  • 1.4K
  • 10 Feb 2022
Topic Review
Automated Tracking Systems for Assessment of Farmed Poultry
One of the most commonly farmed livestock is poultry and their significance is felt on a global scale. Current poultry farming practices result in the premature death and rejection of billions of chickens on an annual basis before they are processed for meat. This loss of life is concerning regarding animal welfare, agricultural efficiency, and economic impacts. The best way to prevent these losses is through the individualistic and/or group level assessment of animals on a continuous basis. On large-scale farms, such attention to detail was generally considered to be inaccurate and inefficient, but with the integration of artificial intelligence (AI)-assisted technology individualised, and per-herd assessments of livestock became possible and accurate.
  • 1.4K
  • 15 Feb 2022
Topic Review
Phonomyography on Perioperative Neuromuscular Monitoring
Muscle contraction by lateral movement of muscle fibers can create acoustic signals with a low frequency, and the signals that occur can be transmitted to the surface of the skin. After collection and filtration, these sound signals will be transferred into electric signals, which can be evaluated quantitatively for perioperative neuromuscular monitoring.
  • 1.4K
  • 12 Apr 2022
Topic Review
Photoacoustic-Based Communication and Localization
The photoacoustic mechanism is commonly used in medical imaging. Yet, it has great potential as a means of air to underwater communication. The use of photoacoustic as a cross-medium communication has high potential to morph the classical way of approaching a solution in underwater applications.
  • 1.4K
  • 20 Jun 2022
Topic Review
Matrix Metalloproteinases in Dental and Periodontal Tissues
Matrix metalloproteinases (MMPs) are significant proteases, of evident contribution in dental and periapical tissue development, health and disease processes, with promising potential for use as diagnostic and prognostic disease biomarkers. Continuing understanding of their role in pathogenesis and progress of different dental, periapical and periodontal lesions, as well as in dentine-pulp wound healing could be a keystone to future diagnostic and therapeutic regimens.
  • 1.4K
  • 25 Aug 2022
Topic Review
Management System (Open Source)
Management System (Open Source) is a socio-technical system that leverages the cumulative knowledge of management practitioners and evidenced based research from the past 130 years. The system was developed by DoD components in partnership with industry experts and academic researchers and builds off of the US Department of Wars version 1.0 open source management system - Training Within Industry. The system integrates the four organizational components of Product, Structure, Process and People. In addition, the system is based on the 4 capabilities of rapid problem solving underlying the Toyota Production System: Derived from the original research of Steven J. Spear (Harvard Business School, Massachusetts Institute for Technology), the system balances the two dimensions of high performing organizations: integrate the whole (product, structure, process & people); and increase the rate of problem solving to manage the whole (4 capabilities outlined above). Fundamentally, the system sets the standards of management by outlining a doctrine of rules, tactics, techniques, procedures & terms. The standards are intended to motivate change by creating a tension between the organization's "current condition" and the "ideal condition" (i.e. True North). The objective of the system is to deliver more value, in less time, at less cost relative to the competition (better, faster, cheaper). For the DoD, competition is defined by the threats posed by current and potential adversaries.
  • 1.4K
  • 02 Oct 2022
Topic Review
Moser–De Bruijn Sequence
In number theory, the Moser–De Bruijn sequence is an integer sequence named after Leo Moser and Nicolaas Govert de Bruijn, consisting of the sums of distinct powers of 4, or equivalently the numbers whose binary representations are nonzero only in even positions. These numbers grow in proportion to the square numbers, and are the squares for a modified form of arithmetic without carrying. No two doubled sequence members differ by a square, and every non-negative integer has a unique representation as the sum of a sequence member and a doubled sequence member. This decomposition into sums can be used to define a bijection between the integers and pairs of integers, to define coordinates for the Z-order curve, and to construct inverse pairs of transcendental numbers with simple decimal representations. A simple recurrence relation allows values of the Moser–De Bruijn sequence to be calculated from earlier values, and can be used to prove that the Moser–De Bruijn sequence is a 2-regular sequence.
  • 1.4K
  • 10 Oct 2022
Topic Review
OpenCog
OpenCog is a project that aims to build an open source artificial intelligence framework. OpenCog Prime is an architecture for robot and virtual embodied cognition that defines a set of interacting components designed to give rise to human-equivalent artificial general intelligence (AGI) as an emergent phenomenon of the whole system. OpenCog Prime's design is primarily the work of Ben Goertzel while the OpenCog framework is intended as a generic framework for broad-based AGI research. Research utilizing OpenCog has been published in journals and presented at conferences and workshops including the annual Conference on Artificial General Intelligence. OpenCog is released under the terms of the GNU Affero General Public License. OpenCog is in use by more than 50 companies, including Huawei and Cisco.
  • 1.4K
  • 28 Oct 2022
Topic Review Peer Reviewed
All-Liquid Metal Battery
A secondary battery (accumulator) employing molten metals or molten metal alloys as active masses at both electrodes and a molten salt as electrolyte in between is called an all-liquid-metal accumulator battery (LMB). Separation of the electrodes and the liquid electrolyte based on segregation caused by different densities and immiscibility of the materials is a characteristic feature. High coulometric storage capabilities of the molten-metal electrodes combined with the relatively low cell voltage and the high stability of the system and the operational principle yield a secondary battery suitable for grid applications and, in particular, for power-quality management and large-scale stationary storage. 
  • 1.4K
  • 04 Feb 2024
Topic Review
Iron-Series Electrocatalysts for Water Splitting
The development of non-noble metal-based electrocatalysts with high performance for hydrogen evolution reaction and oxygen evolution reaction is highly desirable in advancing electrocatalytic water-splitting technology but proves to be challenging. One promising way to improve the catalytic activity is to tailor the d-band center. This approach can facilitate the adsorption of intermediates and promote the formation of active species on surfaces.
  • 1.4K
  • 26 Dec 2022
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