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Topic Review
Bioremediation Techniques
Bioremediation is a process that uses biological organisms to remove or re-treat an environmental pollutant through metabolic processes and plants to eradicate hazardous pollutants and restore the ecosystem to its original condition.
  • 5.9K
  • 24 Apr 2023
Topic Review
Livery
A livery /ˈlɪvəri/ is a uniform, insignia or symbol adorning, in a non-military context, a person, an object or a vehicle that denotes a relationship between the wearer of the livery and an individual or corporate body. Often, elements of the heraldry relating to the individual or corporate body feature in the livery. Alternatively, some kind of a personal emblem or badge, or a distinctive colour, is featured. The word itself derives from the French livrée, meaning dispensed, handed over. Most often it would indicate that the wearer of the livery was a servant, dependant, follower or friend of the owner of the livery, or, in the case of objects, that the object belonged to them. In the late medieval phenomenon of bastard feudalism, livery badges worn by the "retainers" of great lords, sometimes in effect private armies, became a great political concern in England.
  • 5.9K
  • 01 Dec 2022
Topic Review
SRY Gene
SRY: Sex determining region Y. The SRY gene provides instructions for making a protein called the sex-determining region Y protein.
  • 5.9K
  • 22 Dec 2020
Topic Review
Proto-Slavic
Proto-Slavic is the unattested, reconstructed proto-language of all the Slavic languages. It represents Slavic speech approximately from the 2nd millennium B.C. through the 6th century A.D. As with most other proto-languages, no attested writings have been found; scholars have reconstructed the language by applying the comparative method to all the attested Slavic languages and by taking into account other Indo-European languages. Rapid development of Slavic speech occurred during the Proto-Slavic period, coinciding with the massive expansion of the Slavic-speaking area. Dialectal differentiation occurred early on during this period, but overall linguistic unity and mutual intelligibility continued for several centuries, into the 10th century or later. During this period, many sound changes diffused across the entire area, often uniformly. This makes it inconvenient to maintain the traditional definition of a proto-language as the latest reconstructable common ancestor of a language group, with no dialectal differentiation. (This would necessitate treating all pan-Slavic changes after the 6th century or so as part of the separate histories of the various daughter languages.) Instead, Slavicists typically handle the entire period of dialectally-differentiated linguistic unity as Common Slavic. One can divide the Proto-Slavic/Common-Slavic time of linguistic unity roughly into three periods: Authorities differ as to which periods should be included in Proto-Slavic and in Common Slavic. The language described in this article generally reflects the middle period, usually termed Late Proto-Slavic (sometimes Middle Common Slavic) and often dated to around the 7th to 8th centuries. This language remains largely unattested, but a late-period variant, representing the late 9th-century dialect spoken around Thessaloniki in Greek Macedonia, is attested in Old Church Slavonic manuscripts.
  • 5.9K
  • 11 Oct 2022
Topic Review
Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related morbidity and mortality worldwide. Most patients are diagnosed with advanced disease, limiting their options for treatment. While current treatments are adequate for lower staged disease, available systemic treatments are limited, with marginal benefit at best. The below section reviews the incidence, prevalence, healthcare associated cost, and etiologies of HCC. In addition, an overview of the classification, treatment algorithm, and treatment modalities are provided.
  • 5.9K
  • 07 Jan 2021
Topic Review
Steroid-Induced Iatrogenic Adrenal Insufficiency
This entry focuses on steroid-induced adrenal insufficiency (SIAI) in children and discusses the latest findings by surveying recent studies. SIAI is a condition involving adrenocorticotropic hormone (ACTH) and cortisol suppression due to high doses or prolonged administration of glucocorticoids. While its chronic symptoms, such as fatigue and loss of appetite, are nonspecific, exposure to physical stressors, such as infection and surgery, increases the risk of adrenal crisis development accompanied by hypoglycemia, hypotension, or shock. The low-dose ACTH stimulation test is generally used for diagnosis, and the early morning serum cortisol level has also been shown to be useful in screening for the condition. 
  • 5.9K
  • 20 Jan 2021
Topic Review
Mindsponge Mechanism
The mindsponge mechanism (mindsponge framework, mindsponge concept, or mindsponge process) provides a way to explain how and why an individual observes and ejects cultural values conditional on the external setting. The term “mindsponge” derives from the metaphor that the mind is analogized to a sponge that squeezes out unsuitable values and absorbs new ones compatible with its core value. Thanks to the complexity and well-structuring, the mechanism has been used to develop various concepts in multiple disciplines. One such concept is "cultural additivity" (https://www.nature.com/articles/s41599-018-0189-2). Recently, the mindsponge mechanism has been developed into mindsponge theory based on various evidence from natural sciences.
  • 5.9K
  • 01 Sep 2022
Topic Review
L-Carnitine in Mitochondria
Mitochondria control cellular fate by various mechanisms and are key drivers of cellular metabolism. Although the main function of mitochondria is energy production, they are also involved in cellular detoxification, cellular stabilization, as well as control of ketogenesis and glucogenesis. Conditions like neurodegenerative disease, insulin resistance, endocrine imbalances, liver and kidney disease are intimately linked to metabolic disorders or inflexibility and to mitochondrial dysfunction. Mitochondrial dysfunction due to a relative lack of micronutrients and substrates is implicated in the development of many chronic diseases. l-carnitine is a vital molecule that is found in all living cells. It is a quaternary amine (3-hydroxy-4-N-trimethylaminobutyrate) whose main function in mammalian cells is the transfer of long chain fatty acids across the inner mitochondrial membrane for β- oxidation and generation of ATP energy. 
  • 5.9K
  • 11 Mar 2022
Topic Review
Twin-Screw Granulation
Twin-screw granulation (TSG) is a pharmaceutical process that has gained increased interest from the pharmaceutical industry for its potential for the development of oral dosage forms. The technology has evolved rapidly due to the flexibility of the equipment design, the selection of the process variables and the wide range of processed materials. Most importantly, TSG offers the benefits of both batch and continuous manufacturing for pharmaceutical products, accompanied by excellent process control, high product quality which can be achieved through the implementation of Quality by Design (QbD) approaches and the integration of Process Analytical Tools (PAT). 
  • 5.9K
  • 18 May 2021
Topic Review
Authenticity in Art
Authenticity in art is the different ways in which a work of art or an artistic performance may be considered authentic. Denis Dutton distinguishes between nominal authenticity and expressive authenticity. The first refers to the correct identification of the author of a work of art, to how closely a performance of a play or piece of music conforms to the author's intention, or to how closely a work of art conforms to an artistic tradition. The second sense refers to how much the work possesses original or inherent authority, how much sincerity, genuineness of expression, and moral passion the artist or performer puts into the work. A quite different concern is the authenticity of the experience, which may be impossible to achieve. A modern visitor to a museum may not only see an object in a very different context from that which the artist intended, but may be unable to understand important aspects of the work. The authentic experience may be impossible to recapture. Authenticity is a requirement for inscription upon the UNESCO World Heritage List. According to the Nara Document on Authenticity, it can be expressed through 'form and design; materials and substance; use and function; traditions and techniques; location and setting; spirit and feeling; and other internal and external factors.'
  • 5.9K
  • 09 Nov 2022
Topic Review
Distance Measures (Cosmology)
Distance measures are used in physical cosmology to give a natural notion of the distance between two objects or events in the universe. They are often used to tie some observable quantity (such as the luminosity of a distant quasar, the redshift of a distant galaxy, or the angular size of the acoustic peaks in the cosmic microwave background (CMB) power spectrum) to another quantity that is not directly observable, but is more convenient for calculations (such as the comoving coordinates of the quasar, galaxy, etc.). The distance measures discussed here all reduce to the common notion of Euclidean distance at low redshift. In accord with our present understanding of cosmology, these measures are calculated within the context of general relativity, where the Friedmann–Lemaître–Robertson–Walker solution is used to describe the universe.
  • 5.9K
  • 19 Oct 2022
Topic Review
Unintended Consequences
In the social sciences, unintended consequences (sometimes unanticipated consequences or unforeseen consequences) are outcomes of a purposeful action that are not intended or foreseen. The term was popularised in the twentieth century by American sociologist Robert K. Merton and expanded by economist Thomas Sowell and psychologist Stuart Vyse. Unintended consequences can be grouped into three types: Unexpected benefit: A positive unexpected benefit (also referred to as luck, serendipity or a windfall). Unexpected drawback: An unexpected detriment occurring in addition to the desired effect of the policy (e.g., while irrigation schemes provide people with water for agriculture, they can increase waterborne diseases that have devastating health effects, such as schistosomiasis). Perverse result: A perverse effect contrary to what was originally intended (when an intended solution makes a problem worse).
  • 5.8K
  • 14 Oct 2022
Topic Review
LD-Steelmaking
Basic Oxygen Furnace (BOF) steelmaking is, worldwide, the most frequently applied process. According to the world steel organization statistical report, 2021, it saw a total production share of 73.2%, or 1371.2 million tons per year of the world steel production in 2020. The rest is produced in Electric Arc Furnace (EAF)-based steel mills (26.3%), and only a very few open-hearth and induction furnace-based steel mills. The BOF technology remains the leading technology applied based on its undoubted advantages in productivity and liquid steel composition control. The BOF technology started as the LD process 70 years ago, with the first heat applied in November 1952 in a steel mill in Linz, Austria. The name LD was formed from the first letters of the two sites with the first industrial scale plants, Linz and Donawitz, both in Austria. The history and development of the process have been honored in multiple anniversary publications over the last few decades. Nevertheless, the focus of the steel industry worldwide is significantly changing following a social and political trend and the requirement for fossil-free energy generation and industrial production to be in accordance with the world climate targets committed to in relation to the decades leading up to 2050.
  • 5.8K
  • 09 Jun 2022
Topic Review
Disse (Space of Disse)
Space of Disse: a thin perisinusoidal area between the endothelial cells and hepatocytes filled with blood plasma, nutrients and oxygen, but also debris from our organism, that have acquired great importance in liver disease
  • 5.8K
  • 20 Feb 2021
Topic Review
Bone Structure, Its Properties, and Bone Healing Mechanism
Bones are categorized into two major groups, namely cortical bones, and cancellous bones. Cortical bones are compact bones and are responsible for providing mechanical strength, structural rigidity, and movement. They account for 80% of the mass of the bones in the human body. Cancellous bones, also known as trabecular bones, are soft, spongy bones and are responsible for providing structural support to the cortical bones, flexibility, and reduction in weight. 
  • 5.8K
  • 21 Apr 2022
Topic Review
DRDO Rustom
The DRDO Rustom (English: Warrior) is a Medium Altitude Long Endurance unmanned air vehicle (UAV) being developed by Defence Research and Development Organisation for the three services, Indian Army, Indian Navy and the Indian Air Force of the Indian Armed Forces. Rustom is derived from the NAL's LCRA (Light Canard Research Aircraft) developed by a team under the leadership of late Prof Rustom Damania in the 1980s. The UAV will have structural changes and a new engine. Rustom will replace/supplement the Heron UAVs in service with the Indian armed forces.
  • 5.8K
  • 02 Nov 2022
Topic Review
Two-Dimensional Silicon Carbide
Two-dimensional silicon carbide (2D SiC) is a single/few atomic layer of silicon carbide.   2D SiC has a graphene-like honeycomb structure consisting of alternating Si and C atoms. In the monolayer SiC, the C and Si atoms bond through  sp2 hybridization to form the SiC sheet.  As a direct wide bandgap semiconducting material, 2D SiC has the potential to bring revolutionary advances into power electronics, optoelectronic and other SiC-based devices. It can overcome current limitations with silicon, bulk SiC, and gapless graphene. In addition to SiC, which is the most stable form of monolayer silicon carbide, other compositions, i.e. SixCy, are also predicted to be energetically favorable. Depending on the stoichiometry and bonding, monolayer SixCy may behave as a semiconductor, semimetal or topological insulator. With different Si/C ratios, the emerging 2D silicon carbide materials could attain novel electronic, optical, magnetic, mechanical, and chemical properties that go beyond those of graphene, silicene, and already discovered 2D semiconducting materials.
  • 5.8K
  • 08 May 2022
Topic Review
Bongo Drum
Bongos (Spanish: bongó) are an Afro-Cuban percussion instrument consisting of a pair of small open bottomed hand drums of different sizes. They are struck with both hands, most commonly in an eight-stroke pattern called martillo (hammer). They are mainly employed in the rhythm section of son cubano and salsa ensembles, often alongside other drums such as the larger congas and the stick-struck timbales. Bongo drummers (bongoseros) emerged as the only drummers of son cubano ensembles in eastern Cuba toward the end of the 19th century. The instrument remained important as son groups evolved into larger conjuntos and orchestras in Havana in the 1940s, at which point they began to share the stage with congas. Bongos later reached the United States, where they are commonly played in salsa, Afro-Cuban jazz, Latin rock and other genres. Bongo drums are about 20 centimetres (8 in) high and have diameters of approximately 20 centimetres (8 in) and 25 centimetres (10 in) (the smaller drum is called macho, male, and the larger drum, hembra, female). They are the smallest drums in Latin percussion, some models being only 15 centimetres (6 in) in diameter. The shells of the drums and the bridge (the small block that joins them) are usually made of wood, although fiberglass is also common. The heads are typically made of calfskin and attached to the shells via steel hardware that enables their tuning. Originally, metal tacks were used, so tuning had to be done by heating the skins.
  • 5.8K
  • 02 Nov 2022
Topic Review Peer Reviewed
Two-Lane Highways: Indispensable Rural Mobility
Two-lane highways refer to roadways consisting of two lanes in the cross section, one for each direction of travel. Occasionally, passing lanes may be added to one or two sides of the roadway extending the cross section to three or four lanes at those locations. In this entry, two-lane highways strictly refer to roads in rural areas meeting the previous definition and do not include urban and suburban streets.
  • 5.8K
  • 13 Apr 2022
Topic Review
Smart Systems and IoT for Aquaponics Automation
Aquaponics is an innovative, smart, and sustainable agricultural technology that integrates aquaculture (farming of fish) with hydroponics in growing vegetable crops symbiotically. The correct implementation of aquaponics helps in providing healthy organic foods with low consumption of water and chemical fertilizers. Numerous research attempts have been directed toward real implementations of this technology feasibly and reliably at large commercial scales and adopting it as a new precision technology. For better management of such technology, there is an urgent need to use the Internet of things (IoT) and smart sensing systems for monitoring and controlling all operations involved in the aquaponic systems.
  • 5.8K
  • 11 Aug 2022
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