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Apostles in Christianity
In Christian theology and ecclesiology, apostles, particularly the Twelve Apostles (also known as the Twelve Disciples or simply the Twelve), were the primary disciples of Jesus according to the New Testament. During the life and ministry of Jesus in the 1st century AD, the apostles were his closest followers and became the primary teachers of the gospel message of Jesus. There is also an Eastern Christian tradition derived from the Gospel of Luke of there having been as many as seventy apostles during the time of Jesus' ministry. The commissioning of the Twelve Apostles during the ministry of Jesus is recorded in the Synoptic Gospels. After his resurrection, Jesus sent eleven of them (minus Judas Iscariot, who by then had died) by the Great Commission to spread his teachings to all nations. This event has been called the Dispersion of the Apostles. In the Pauline epistles, Paul, although not one of the original twelve, described himself as an apostle, saying he was called by the resurrected Jesus himself during his Road to Damascus event. He later describes himself as "the apostle of the Gentiles". In the Book of Acts he and Barnabas were allotted the roles of apostle in the church. In modern usage, missionaries under Pentecostal movements often refer to themselves as apostles, a practice which stems from the Latin equivalent of apostle, i.e. missio, the source of the English word missionary. For example, Saint Patrick (AD 373–463) was the "Apostle of Ireland", Saint Boniface (680–755) was the "Apostle to the Germans", Saint José de Anchieta (1534–1597) was the "Apostle of Brazil" and Saint Peter of Betancur (1626–1667) was the "Apostle of Guatemala". The Church of Jesus Christ of Latter-Day Saints has always had, among its leadership, twelve individuals identified as apostles. Their primary role is to teach and testify of Jesus throughout the world. The period of early Christianity during the lifetimes of the apostles is called the Apostolic Age. During the 1st century AD, the apostles established churches throughout the territories of the Roman Empire and, according to tradition, through the Middle East, Africa, and India . Of the tombs of the apostles, all but two are claimed by premises of the Catholic Church, half of them located in the Diocese of Rome.
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  • 25 Oct 2022
Topic Review
Thus Have I Heard
Thus have I heard (Pali: Evaṃ me suttaṃ; Sanskrit: Evaṃ mayā śrūtaṃ) is the common translation of the first line of the standard introduction (Pāli and Sanskrit: nidāna) of Buddhist discourses. This phrase serves to confirm that the discourse is coming from the Buddha himself, as a "seal of authenticity". Buddhist tradition maintains that the disciple Ānanda used the formula for the first time, as a form of personal testimony, but this is disputed by some scholars. It is also disputed how the phrase relates to the words that follow, and several theories have been developed with regard to how the text was originally intended to be read. The formula has also been used in later Mahāyāna and Vajrayāna discourses.
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  • 25 Oct 2022
Topic Review
Pressure Ulcer
Pressure ulcers, also known as pressure sores, bed sores or pressure injuries, are localised damage to the skin and/or underlying tissue that usually occur over a bony prominence as a result of usually long-term pressure, or pressure in combination with shear or friction. The most common sites are the skin overlying the sacrum, coccyx, heels, and hips, though other sites can be affected, such as the elbows, knees, ankles, back of shoulders, or the back of the cranium. Pressure ulcers occur due to pressure applied to soft tissue resulting in completely or partially obstructed blood flow to the soft tissue. Shear is also a cause, as it can pull on blood vessels that feed the skin. Pressure ulcers most commonly develop in individuals who are not moving about, such as those who are on chronic bedrest or consistently use a wheelchair. It is widely believed that other factors can influence the tolerance of skin for pressure and shear, thereby increasing the risk of pressure ulcer development. These factors are protein-calorie malnutrition, microclimate (skin wetness caused by sweating or incontinence), diseases that reduce blood flow to the skin, such as arteriosclerosis, or diseases that reduce the sensation in the skin, such as paralysis or neuropathy. The healing of pressure ulcers may be slowed by the age of the person, medical conditions (such as arteriosclerosis, diabetes or infection), smoking or medications such as anti-inflammatory drugs. Although often prevented and treatable if detected early, pressure ulcers can be very difficult to prevent in critically ill people, frail elders and individuals with impaired mobility such as wheelchair users (especially where spinal injury is involved). Primary prevention is to redistribute pressure by regularly turning the person. The benefit of turning to avoid further sores is well documented since at least the 19th century. In addition to turning and re-positioning the person in the bed or wheelchair, eating a balanced diet with adequate protein and keeping the skin free from exposure to urine and stool is important. The rate of pressure ulcers in hospital settings is high; the prevalence in European hospitals ranges from 8.3% to 23%, and the prevalence was 26% in Canadian healthcare settings from 1990 to 2003. In 2013, there were 29,000 documented deaths from pressure ulcers globally, up from 14,000 deaths in 1990.
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  • 25 Oct 2022
Topic Review
Proto-Austronesian
Proto-Austronesian (commonly abbreviated as PAN or PAn) is a proto-language. It is the reconstructed ancestor of the Austronesian languages, one of the world's major language families. Lower-level reconstructions have also been made, and include Proto-Malayo-Polynesian, Proto-Oceanic, and Proto-Polynesian. Recently, linguists such as Malcolm Ross and Andrew Pawley have built large lexicons for Proto-Oceanic and Proto-Polynesian.
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  • 25 Oct 2022
Topic Review
Torrance Tests of Creative Thinking
The Torrance Tests of Creative Thinking is a test of creativity.
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  • 25 Oct 2022
Topic Review
AMPT
Alpha-methyl-p-tyrosine (AMPT) is a tyrosine hydroxylase enzyme inhibitor and is therefore a drug involved in inhibiting the catecholamine biosynthetic pathway. AMPT inhibits tyrosine hydroxylase whose enzymatic activity is normally regulated through the phosphorylation of different serine residues in regulatory domain sites. Catecholamine biosynthesis starts with dietary tyrosine, which is hydroxylated by tyrosine hydroxylase and it is hypothesized that AMPT competes with tyrosine at the tyrosine-binding site, causing inhibition of tyrosine hydroxylase. It has been used in the treatment of pheochromocytoma. It has been demonstrated to inhibit the production of melanin.
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  • 25 Oct 2022
Topic Review
Mohammed Bin Rashid Space Centre
The Mohammed Bin Rashid Space Centre (MBRSC) (Arabic: مركز محمد بن راشد للفضاء), is a Dubai government organisation working on the UAE space program, which includes various space satellite projects, the Emirates Mars Mission, and the UAE astronaut programme. The centre actively works to promote space science and research in the region. The centre encompasses the Emirates Institution for Advanced Science and Technology (EIAST).
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  • 25 Oct 2022
Topic Review
Cousin
Most generally, in the lineal kinship system used in the English-speaking world, a cousin is a type of familial relationship in which two relatives are two or more familial generations away from their most recent common ancestor. Commonly, "cousin" refers to a first cousin – a relative of the same generation whose most recent common ancestor with the subject is a grandparent. Degrees and removals are separate measures used to more precisely describe the relationship between cousins. Degree measures the separation, in generations, from the most recent common ancestor(s) to a parent of one of the cousins (whichever is closest), while removal measures the difference in generations between the cousins themselves, relative to their most recent common ancestor(s). To illustrate usage, a second cousin is a cousin with a degree of two; there are three (not two) generations from the common ancestor(s). When the degree is not specified, first cousin is assumed. A cousin "once removed" is a cousin with one removal. When the removal is not specified, no removal is assumed. Various governmental entities have established systems for legal use that can precisely specify kinship with common ancestors any number of generations in the past; for example, in medicine and in law, a first cousin is a type of third-degree relative.
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  • 25 Oct 2022
Topic Review
Substance Dependence
Substance dependence, also known as drug dependence, is a biopsychological situation where-by an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance, because of an adaptive state that has developed with the individual from psychoactive substance consumption, which results in the experience of withdrawal, which necessitates the re-consumption of the drug. A drug addiction, a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences. An addictive drug is a drug which is both rewarding and reinforcing. ΔFosB, a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral and drug addictions, but not dependence. The International Classification of Diseases classifies substance dependence as a mental and behavioural disorder. Within the framework of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), substance dependence is redefined as a drug addiction, and can be diagnosed without the occurrence of a withdrawal syndrome. It was described accordingly: "When an individual persists in use of alcohol or other drugs despite problems related to use of the substance, substance dependence may be diagnosed. Compulsive and repetitive use may result in tolerance to the effect of the drug and withdrawal symptoms when use is reduced or stopped. This, along with Substance Abuse are considered Substance Use Disorders." In the DSM-5 (released in 2013), substance abuse and substance dependence have been merged into the category of substance use disorders and they no longer exist as individual diagnoses.
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  • 25 Oct 2022
Topic Review
Multiply (Website)
{{Multiple issues| Multiply was a social networking service with an emphasis on allowing users to share media – such as photos, videos and blog entries – with their "real-world" network. The website was launched in March 2004 and was privately held with backing by VantagePoint Venture Partners, Point Judith Capital, Transcosmos, and private investors. Multiply had over 11 million registered users. The company was headquartered in Boca Raton, Florida but moved to Jakarta, Indonesia early in 2012 and recently announced intentions to switch to e-commerce, dropping the social networking aspect entirely. Quantcast estimates Multiply had 2.47 million monthly U.S. unique visitors at their peak on July 30, 2012. On Multiply, a user's network was made up of their direct contacts, as well as others who are closely connected to them through their first-degree relationships. Additionally, users were encouraged to specify the nature of their relationship with one another, making it possible to share content with their entire network of closely related people, or subsets thereof including friends, family, professional contacts, and so on. May 31, 2013 officially marked the closing of their operations after more than 9 years and 2 months following its inability to make a profit and was later dissolved and have its assets redistributed after filing articles of dissolution due to financial difficulties whilst expressing the hope that the website might reorganize, retain Jakarta, Indonesia as headquarters, and reopen as a social networking service in the future. When business stabilized, the management began to re-open the site and to recovering hosted blogs, videos, photos and messaging.
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  • 26 Oct 2022
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