Summary

Gastrointestinal disease is a very common and frequently occurring disease, with a wide range of types and a total incidence of about 20% of the population. The cause of gastrointestinal disease is the imbalance between the protective mechanism and the injury mechanism of the human body. While traditional medicine kills harmful bacteria in the stomach, it also kills the beneficial bacteria necessary for the stomach. Although the symptoms are alleviated and inflammation is eliminated, the reduction of beneficial bacteria reduces the gastrointestinal immunity. Once the drug is stopped, it is easy to re-infect. There are many reasons for stomach problems, including genetics, environment, diet, drugs, bacterial infections, etc., as well as smoking and excessive alcohol consumption. This collection of entries aims to collect various items related to the topic of gastrointestinal diseases, such as clinical care, case cases, disease research, etc., to help people increase their knowledge and understanding of this common disease

Expand All
Entries
Topic Review Video
‘Teratoid’ Hepatoblastoma
Liver neoplasms are quite rare in childhood. They often involve 6.7 cases per 10 million children aged 18 years or younger. Hepatoblastoma (HB) is the most frequent tumor, but this neoplasm’s rarity points essentially to the difficulty of performing biologic studies and large-scale therapeutic trials. On the pathological ground, HB is separated into an entirely epithelial neoplasm or a mixed neoplasm with epithelial and mesenchymal components. This last category has been further subdivided into harboring teratoid features or not. The ‘teratoid’ HB includes a mixture of components with heterologous origin.
  • 789
  • 24 Apr 2022
Topic Review
Lipids and Gut Microbiota Alterations
Advances in sequencing technologies over the past 15 years have led to a substantially greater appreciation of the importance of the gut microbiome to the health of the host. Recent outcomes indicate that aspects of nutrition, especially lipids (exogenous or endogenous), can influence the gut microbiota composition and consequently, play an important role in the metabolic health of the host. Thus, there is an increasing interest in applying holistic analytical approaches, such as lipidomics, metabolomics, (meta)transcriptomics, (meta)genomics, and (meta)proteomics, to thoroughly study the gut microbiota and any possible interplay with nutritional or endogenous components.
  • 771
  • 21 Apr 2022
Topic Review
Biotics and the Gut Barrier
Increased gut permeability is suggested to be involved in the pathogenesis of a growing number of disorders. The altered intestinal barrier and the subsequent translocation of bacteria or bacterial products into the internal milieu of the human body induce the inflammatory state. Gut microbiota maintains intestinal epithelium integrity. Since dysbiosis contributes to increased gut permeability, the interventions that change the gut microbiota and correct dysbiosis are suggested to also restore intestinal barrier function
  • 1.1K
  • 27 Apr 2022
Topic Review
Inflammatory Bowel Disease and Reproductive Health
Despite the fact that knowledge on obstetrical management of Inflammatory Bowel Diseases (IBDs) has greatly improved over the years, many patients still actively avoid pregnancy for fear of adverse maternal or neonatal outcomes, of adverse effects of pregnancy on the disease activity, of eventual IBD inheritance, or of an increased risk of congenital malformations. Indeed, though data prove that fertility is hardly affected by the disease, a reduced birth rate is nevertheless observed in patients with IBD. Misconceptions on the safety of drugs during gestation and breastfeeding may influence patient choice and negatively affect their serenity during pregnancy or lactation.
  • 471
  • 20 Apr 2022
Topic Review
Anisakiasis
Anisakiasis is a zoonosis caused by the ingestion of raw or undercooked seafood infected with third-stage larvae (L3) of the marine nematode Anisakis. Based on L3 localization in human accidental hosts, gastric, intestinal or ectopic (extra-gastrointestinal) anisakiasis can occur, in association with mild to severe symptoms of gastrointestinal and/or allergic nature.
  • 582
  • 20 Apr 2022
Topic Review
Intestinal ‘Infant-Type’ Bifidobacteria
To utilize host-derived nutrients, intestinal infant-type bifidobacteria have evolved a series of complex genetic pathways to metabolize human milk oligosaccharides (HMOs).
  • 700
  • 18 Apr 2022
Topic Review
Anal Stenosis
Anal stenosis (AS) is defined as anatomical or functional narrowing of the anal canal, which can result from inflammatory bowel diseases, radiation therapy, congenital malformations, or excisional hemorrhoidectomy. The anatomical AS is related to the increased fibrous scar tissue forming, which disables stretching of the anal canal. The leading cause of the anatomical AS is excisional hemorrhoidectomy that is often the chosen treatment for grade III and IV hemorrhoidal disease.
  • 2.0K
  • 18 Apr 2022
Topic Review
Microbiota Interventions and Autism Spectrum Disorders
The alteration of the microbiota–gut–brain axis has been recently recognized as a critical modulator of neuropsychiatric health and a possible factor in the etiopathogenesis of autism spectrum disorders (ASD).
  • 627
  • 18 Apr 2022
Topic Review
Norovirus
Noroviruses (NoVs) are one of the emerging and rapidly spreading groups of pathogens threatening human health.  A reduction in sporadic NoV infections was noted following the start of the COVID-19 pandemic, but the return of NoV gastroenteritis during the COVID-19 pandemic has been noted recently. Research in recent years has shown that different virus strains are associated with different clinical characteristics; moreover, there is a paucity of research into extraintestinal or unusual complications that may be associated with NoV. 
  • 777
  • 14 Apr 2022
Topic Review
Association between Dietary Inflammatory Index and Colorectal Cancer
The advent of the Dietary Inflammatory Index (DII) provides a quantitative means to study the relationship between the pro-inflammatory diet and CRC. It allows the assessment of the inflammatory potential of individual food items using an FFQ, by which a DII score can be calculated. A higher DII score suggests a stronger inflammatory potential of a food item. The Dietary Inflammatory Index (DII) was extensively used to examine the inflammatory potential of diet related to colorectal cancer (CRC).
  • 429
  • 13 Apr 2022
  • Page
  • of
  • 39

Featured Entry Collections

>>