Summary

On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Caused by SARS-CoV-2, COVID-19 continues nearly 18 months later to present significant challenges to health systems and public health in both hemispheres, as well as the economies of every country. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed many hospitals and clinics and continue to do so in many countries. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This entry collection aims to gather diverse fields about COVID-19, including in epidemiology, public health, medicine, genetics, systems biology, informatics, data science, engineering, sociology, anthropology, nursing, environmental studies, statistics, and psychology.

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Entries
Topic Review
Thrombotic Disorders and COVID-19 Vaccines
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has affected hundreds of millions worldwide, leading to nearly 7 million deaths globally, although now declared not a worldwide concern anymore. Strenuous research and analysis of various vaccine advances led to the development of multiple COVID-19 vaccines in less than a year from the pandemic’s beginning. Different types of vaccines, such as mRNA vaccines, DNA vaccines, viral vector vaccines, and inactivated virus vaccines have been approved and have shown a high degree of efficacy with variable protective levels of up to 95% (70–95% range) in vaccinated individuals against COVID-19.
  • 932
  • 01 Nov 2023
Topic Review
Drug Remedies and Host Cell Responses for COVID-19
In light of the COVID-19 global pandemic caused by SARS-CoV-2, ongoing research has centered on minimizing viral spread either by stopping viral entry or inhibiting viral replication. Repurposing antiviral drugs, typically nucleoside analogs, has proven successful at inhibiting virus replication. 
  • 874
  • 20 Oct 2023
Topic Review
Accessible Higher-Education: A Framework for Continuous Improvement
The SARS-CoV-2 Coronavirus pandemic (COVID-19) forced educational institutions to move their programs to the virtual world, revealing needs such as the lack of accessibility of online resources and content. In this context, the Erasmus+ project "Technological Assistance to Accessibility in Virtual Higher Education (EduTech)”, proposed tools and knowledge focused on improving accessibility in Higher Education Institutions (HEIs). In this article, a framework that integrates all the findings of the EduTech project is presented. The proposed framework is aimed at facilitating the adoption of good practices related to technological accessibility in HEI. The framework considers the limitations and needs of the institutions in terms of governance and resources for improving accessibility. The framework was adopted by four Latin American HEIs to establish a continuous improvement strategy according to their needs and current level of accessibility focus. This research also shows the results and suggests that the proposal is adaptable to the needs of HEIs, allowing its implementation regardless of their organizational structure and their current level of attention to accessibility.
  • 1.6K
  • 16 Oct 2023
Topic Review
Disseminated Intravascular Coagulopathy and Venous Thromboembolism in COVID-19
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China, causes acute atypical respiratory symptoms and has led to profound changes in  lives. COVID-19 is characterized by a wide range of complications, which include pulmonary embolism, thromboembolism and arterial clot formation, arrhythmias, cardiomyopathy, multiorgan failure, and more. The disease has caused a worldwide pandemic, and despite various measures such as social distancing, various preventive strategies, and therapeutic approaches, and the creation of vaccines, the novel coronavirus infection (COVID-19) still hides many mysteries for the scientific community.
  • 1.0K
  • 11 Oct 2023
Biography
Wenliang Li
Wenliang Li, Manchu ethnic Chinese, was an ophthalmologist in Wuhan Central University. He reported the notice on the SARS-structured virus found in patients in the hospital and his advice for caution was soon spread on Chinese social media [1]. Although a member of the Communist Party of China, Wenliang Li was soon called on by the local police for admonition for "spreading rumors harmful to t
  • 1.1K
  • 15 Oct 2023
Topic Review
Pandemic-Resilient Energy-Hub-Based Smart Cities
Although the severity of the COVID-19 pandemic has appears to have subsided in most parts of the world, nevertheless, in addition to six million deaths, it has yielded unprecedented challenges in the economy, energy, education, urban services, and healthcare sectors. Meanwhile, according to reports, smart solutions and technologies have manifested considerable success in achieving pandemic-resilient cities. 
  • 872
  • 25 Sep 2023
Topic Review
IoMT Based Big Data Framework for COVID-19
The Internet of Medical Things (IoMT) is transforming modern healthcare systems by merging technological, economical, and social opportunities and has recently gained traction in the healthcare domain. The severely contagious respiratory syndrome coronavirus called COVID-19 has emerged as a severe threat to public health. COVID-19 is a highly infectious virus that is spread by person-to-person contact.
  • 694
  • 22 Sep 2023
Topic Review
Africa Vaccine Technology Transfer
The rampant spread of the COVID-19 infection poses a grave and formidable challenge to global healthcare, with particular concern to the inhabitants of the African continent. In response to these pressing concerns, different strategies have been employed to combat the emergence of this insidious disease, encompassing crucial measures such as physical distancing, the utilization of face masks, meticulous hand hygiene, and widespread vaccination campaigns.
  • 1.4K
  • 15 Sep 2023
Topic Review
Endothelial Function Evaluation on Pregnant COVID-19 Patients
Pregnancy with SARS-CoV-2 infection can raise the risk of many complications, including severe COVID-19 and maternal–fetal adverse outcomes. Additionally, endothelial damage occurs as a result of direct SARS-CoV-2 infection, as well as immune system, cardiovascular, and thrombo-inflammatory reactions. The endothelium is the key regulator of vascular homeostasis, as it determines vascular tone, smooth muscle cell proliferation, vessel wall inflammation, and platelet aggregation.
  • 706
  • 14 Sep 2023
Topic Review
Antimicrobial Resistance with Infectious Diseases during Hajj
Hajj pilgrimage is a large mass gathering global event that may facilitate the spread and emergence of various infectious diseases as well as antimicrobial resistance (AMR) in a local and global scenario. Planning and preparing for these public health issues is a challenging and complex process for the Kingdom of Saudi Arabia (KSA) health authorities. Despite multiple efforts for the prevention and treatment of infectious diseases through longtime funding in education and medical care, the prevalence of infectious disease is still high among Hajj pilgrims. The commonly observed infectious diseases during Hajj include respiratory tract infections (influenza and pneumonia), urinary tract infections and skin infections that may necessitate the use of antimicrobials. Beta-lactams are used as a first-line treatment for hospital acquired infections as well as community acquired infections due to their broad-spectrum activity. However, most of the bacterial isolates such as Staphylococcus spp., Pseudomonas spp. and E. coli are resistant to beta-lactams. Irrational use of antimicrobials, lack of infection prevention practices and suboptimal healthcare access further exacerbate the risk of spreading AMR among Hajj pilgrims.
  • 1.7K
  • 08 Sep 2023
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