Topic Review
A Framework for Developing Environmental Justice Indicators
Environmental justice (EJ) is a broad discipline that attempts to understand and redress unfair exposure to unhealthy environmental conditions. EJ is often made measurable with indicators, however the capabilities and the limitations of EJ indicators can be difficult for policy makers to understand. Useful EJ indicators are invariably made up of at least two measures from a combination of the environment, demography, epidemiology or procedures elements. Furthermore, the way that measures are combined determines the type of EJ indicator that is created, enabling different facets of an issue to be understood.  
  • 758
  • 12 Apr 2022
Topic Review
A Functional Minigenome of Parvovirus B19
Parvovirus B19 (B19V) is a human pathogenic virus of clinical relevance, characterized by a selective tropism for erythroid progenitor cells in bone marrow. Relevant information on viral characteristics and lifecycle can be obtained from experiments involving engineered genetic systems in appropriate in vitro cellular models. Previously, a B19V genome of defined consensus sequence was designed, synthesized and cloned in a complete and functional form, able to replicate and produce infectious viral particles in a producer/amplifier cell system.
  • 460
  • 17 Jan 2022
Topic Review Peer Reviewed
A General Description of Karst Types
This study includes a general description of the Earth’s karst types based on literary data and field observations. An improved classification of karst types distinguishes the main group, group, and subgroup; and, a division of karst types involves a main karst type, karst type, subtype, variety, and non-individual karst type. The relation between karst type and karst area is described. The role of various characteristics of karsts in the development of primary, secondary, and tertiary karst types is analyzed. Their structure is studied, which includes a geomorphic agent, process, feature, feature assemblage, karst system and the characteristics of the bearing karst area. Dominant, tributary, and accessory features are distinguished. The conditions of the stability and the development of types are studied, transformation ways are classified, and the effect of climate on types is described.
  • 460
  • 26 Sep 2022
Topic Review
A Generative Adversarial Network Technique for Ransomware Behavior Prediction
The ransomware attacks threaten not only personal files but also critical infrastructure like smart grids, necessitating early detection before encryption occurs. Current methods, reliant on pre-encryption data, suffer from insufficient and rapidly outdated attack patterns, despite efforts to focus on select features. Such an approach assumes that the same features remain unchanged. This approach proves ineffective due to the polymorphic and metamorphic characteristics of ransomware, which generate unique attack patterns for each new target, particularly in the pre-encryption phase where evasiveness is prioritized. 
  • 384
  • 30 Oct 2023
Topic Review
A Glimpse of Silver Nanoparticles
Silver (Ag) is a chemical element that has provided promising results in various fields such as medicine, electronics, and household applications, e.g., silver sulfadiazine has been used as a standard treatment for burn wounds to prevent the formation of biofilm on the wound area, thus enhancing the wound recovery progress. Silver is a part of transition metals and has been classified as a precious metal due to its decreasing availability. Silver has interesting properties, yet the uses of the materials are limited due to silver instability towards oxygen. Silver metal will oxidize spontaneously when exposed to free oxygen molecules. In these past few years, there has been an unprecedented rise in the application of nanoscience and nanotechnologies which lead to substantial progress in the production of nanomaterials. Thus, it had made possible to produce silver in nanoscale and these emerging nanoparticle products have attracted interest due to their physical, chemical, and biological properties in comparison with their macro-scaled counterparts. These properties are being assessed through various analytical techniques.
  • 580
  • 19 Feb 2021
Topic Review
A Graphene-PEDOT
A graphene and poly (3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) modified conductive paper-based electrochemical impedance spectroscopy (EIS) aptasensor has been successfully fabricated by a simple and continuous coating process. A graphene/PEDOT:PSS modified paper electrode forms the nanocomposite providing a conductive and sensitive substrate for further aptamer functionalization of the biosensor. This low-cost paper-based aptasensor exhibits its sensitivity to carcinoembryonic antigens (CEA) in standard buffer solutions and human serum samples in a linear range of 0.77–14 ng·mL−1. The limit of detection (LOD) is found to be 0.45 ng·mL−1 and 1.06 ng·mL−1 for CEA in both samples, separately. This aptamer-based sensing device was also evaluated and received a good correlation with the immunoassay detection method. The proposed paper-based aptasensor has demonstrated its potential as a rapid simple point-of-care analytical platform for early cancer diagnosis in less developed areas where manufacturing facilities, analytical instruments, and trained specialists are limited.
  • 1.1K
  • 01 Nov 2020
Topic Review
A healthy socioemotional foundation in education
In the early school years, the emphasis is more and more on cognitive output factors. Non-cognitive development is receiving less attention than before, though such factors are important determinants of academic success. This study focuses on socioemotional characteristics, more specifically, on attitudes, behavior, and relationships of 6500 grade 2 pupils who participated in the representative Dutch large-scale cohort study COOL5-18. The results showed that the teachers rated their pupil’s work attitude as lower than their behavior and popularity. They were more positive regarding their relationship with the pupils. More important was that there were differences according to the pupils’ social and ethnic/immigrant backgrounds: ethnic minority/immigrant pupils scored less positive on all non-cognitive characteristics than native Dutch pupils, and the higher the parental educational level, the more favorable their children performed on the non-cognitive characteristics. These findings are discussed and possible solutions are presented.
  • 670
  • 20 Apr 2022
Topic Review
A History of Myology
Myology is the science that studies muscles, their physical structure, type of fibers, specific function, and the connections with nerves and between different muscle groups. Interest in Myology includes also neuromuscular disorders. For most of the 20th century, Myology was considered a part of Neurology, while currently it is recognized as an autonomous discipline both at the research and the medical level. From a research point of view, we have witnessed the birth and flourishing of new scientific societies, such as the European Society for Muscle Research (1970), the Mediterranean Society of Myology (1993), the World Muscle Society (1995), the Institute of Myology (1996), the Italian Association of Myology (2000), the British Myology Society (2009), the French Society of Myology(2011), and numerous conferences concerning neuromuscular disorders, In particular, the annual meetings of the World Muscle Society and the Italian Association of Myology will have this year at their future meetings respectively in Charleston and Padova.
  • 855
  • 09 May 2023
Topic Review Peer Reviewed
A Journey to Hear: The Evolution of Cochlear Implants
Cochlear implants (CIs), a revolutionary breakthrough in auditory technology, have profoundly impacted the lives of individuals with severe hearing impairment. Surgically implanted behind the ear and within the delicate cochlea, these devices represent a direct pathway to restoring the sense of hearing. Implanting hope alongside innovation, their captivating history unfolds through pivotal dates and transformative milestones. From the first human implantation by Drs. William House and John Doyle in 1961 to FDA approval in 1984, each step in their evolution mirrors a triumph of human ingenuity. The 1990s witnessed significant miniaturization, enhancing accessibility, while the 21st century brought about improvements in speech processing and electrode technology. These strides have elevated CIs beyond functional devices to life-changing instruments, enriching both auditory experiences and communication skills. This entry delves into the captivating history of CIs, spotlighting key dates that paint a vivid picture of challenges overcome and remarkable progress achieved. It explores the people and moments that defined their development, ultimately shaping these implants into indispensable tools that continually redefine the landscape of hearing assistance.
  • 689
  • 12 Jan 2024
Topic Review
A Journey to Produce Functional Beta Cells
Due to a pressing worldwide situation with diabetes, ideas to use direct differentiation from embryonic stem cells (ESCs) and pluripotent stem cells (PSCs) to produce beta cells have surfaced. Stem cells are thought to be an ideal source of all cell types including pancreatic beta cells. 
  • 383
  • 28 Jun 2022
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