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Topic Review
99mTc-Aprotinin in Diagnosis of Cardiac Amyloidosis
Aprotinin is a serine protease inhibitor. Several studies investigated the use of 99mTc-labelled Aprotinin as an amyloid seeker. In vitro tests showed high binding affinity for several types of amyloid fibrils accompanied by an excellent specificity. Initial human studies demonstrated good accuracy in detecting cardiac involvement. Scintigraphy results were confirmed in a group of 28 endomyocardial biopsies. Unfortunately, clinical studies were halted because of a temporary suspension of the vector protein (Trasylol) and public health concerns over prion contamination of the bovine origin compound. To obviate these limitations, efforts have been made to label a recombinant Aprotinin with 99mTc, which exhibits the same affinity for h-insulin fibrils.
  • 297
  • 20 Jun 2022
Topic Review
9Dragons
9Dragons is a martial arts-themed massively multiplayer online role playing game, developed by Korean video game company Indy21. The game features 3D graphics and traditional Massively multiplayer online game control schemes. Set in China during the Ming Dynasty, it includes actual Chinese geography and historical features such as the Great Wall of China and the famous Shaolin Monastery.
  • 855
  • 17 Nov 2022
Topic Review
9K111 Fagot
The 9K111 Fagot (Russian: Фагот; "bassoon") is a second-generation tube-launched SACLOS wire-guided anti-tank missile system of the Soviet Union for use from ground or vehicle mounts. The 9K111 Fagot missile system was developed by the Tula KBP Design Bureau for Instrument Building. "9M111" is the GRAU designation of the missile. Its NATO reporting name is AT-4 Spigot.
  • 3.0K
  • 21 Oct 2022
Topic Review
9M133 Kornet
The 9M133 Kornet (Russian: Корнет; "Cornet", NATO reporting name AT-14 Spriggan, export designation Kornet-E) is a modern Russian man-portable anti-tank guided missile (ATGM) intended for use against main battle tanks. It was first introduced into service with the Russian army in 1998. The Kornet is among the most capable Russian ATGMs. It is not intended to fully replace previous systems, due to its high cost. The Kornet comes in variants with thermobaric warheads for use against soft targets. It was further developed into the 9M133 Kornet-EM, which has increased range, fire-and-forget capability, and an improved warhead. The Kornet has been widely exported and is produced under license in several countries. It was first used in combat in 2003 and has since been used in many conflicts. The NATO reporting name AT-14 Spriggan is derived from the spriggan, a legendary creature from Cornish faery lore.
  • 5.5K
  • 08 Nov 2022
Topic Review
9q22.3 Microdeletion
9q22.3 microdeletion is a chromosomal change in which a small piece of chromosome 9 is deleted in each cell. The deletion occurs on the long (q) arm of the chromosome in a region designated q22.3. This chromosomal change is associated with delayed development, intellectual disability, certain physical abnormalities, and the characteristic features of a genetic condition called Gorlin syndrome.
  • 613
  • 23 Dec 2020
Topic Review
A 4.0-based soft transducer for vitals telemonitoring
This work addresses the design, development and implementation of a 4.0-based wearable soft transducer for patient-centered, vitals telemonitoring. In particular, first, the soft transducer measures hypertension-related vitals (heart rate, oxygen saturation and systolic/diastolic pressure), and sends the data to a remote database (which can be easily consulted both by the patient and the physician). In addition to this, a dedicated deep learning algorithm, based on a Long-Short-Term-Memory Autoencoder, was designed, implemented and tested for providing an alert when the patient's vitals exceed certain thresholds, which are automatically personalized for the specific patient. Furthermore, a mobile application (EcO2u) was developed to manage the entire data flow and facilitate the data fruition; this application also implements an innovative face-detection algorithm that ensures the identity of the patient. The robustness of the proposed soft transducer was validated experimentally on five individuals, who used the system for 30 days. Experimental results demonstrated an accuracy in anomaly detection greater than 93 %, with a true positive rate of more than 94 %.
  • 424
  • 19 Apr 2022
Topic Review
A Beginner's Python Tutorial
Python is an interpreted programming language.
  • 882
  • 04 Nov 2022
Topic Review
A Benchmark Dataset for Wearable Low-Light Pedestrian Detection
Detecting pedestrians in low-light conditions is challenging, especially in the context of wearable platforms. Infrared cameras have been employed to enhance detection capabilities, whereas low-light cameras capture the more intricate features of pedestrians. With this in mind, a low-light pedestrian detection (called HRBUST-LLPED) dataset by capturing pedestrian data on campus using wearable low-light cameras is introduced.
  • 246
  • 19 Dec 2023
Topic Review
A Bioinformatics Workflow of Metabolomics Analysis
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The key purpose of metabolomics is to identify the metabolites corresponding to each biological phenotype, and then provide an analysis of the mechanisms involved. Although metabolomics is important to understand the involved biological phenomena, the approach’s ability to obtain an exhaustive description of the processes is limited. Thus, an analysis-integrated metabolomics, transcriptomics, proteomics, and other omics approach is recommended. Such integration of different omics data requires specialized statistical and bioinformatics software. 
  • 1.8K
  • 25 May 2022
Topic Review
A Blockchain Prototype on Container Shipping Operations
Blockchain technology has been proposed as a solution to these concerns. It is a decentralised ledger system that can record and track transactions in a secure and transparent manner. Moreover, it is possible to create a tamper-proof record of the container’s movements and status throughout the shipping process using blockchain to record the data from e-seals.
  • 336
  • 09 Aug 2023
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