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Topic Review
Vascular Calcification
A variety of actively regulated processes on cellular and systemic level with various contributing and inhibiting factors can result in vascular calcification (VC). Currently, treatment is limited to management of risk factors including regulation of the calcium-phosphate metabolism. Due to the complex pathophysiology, the mechanisms underlying ectopic calcification are studied in various, distinctly different research models. Beside in vitro models using cells of different origin, ex vivo settings using aortic tissue are available. In addition, various in vivo disease-induced animal models are currently used in research. All of these experimental settings depict (patho)physiologic mechanisms within the vascular calcification process.
  • 935
  • 29 Oct 2020
Topic Review
Vascular bundles
Vascular bundles play important roles in transporting nutrients, growth signals, amino acids, and proteins between aerial and underground tissues. 
  • 7.0K
  • 26 Feb 2021
Topic Review
Vascular Anomalies
Vascular anomalies include various diseases, which are classified into two types according to the International Society for the Study of Vascular Anomalies (ISSVA) classification: vascular tumors with proliferative changes of endothelial cells, and vascular malformations primarily consisting of structural vascular abnormalities. Vascular lesions had been habitually termed ‘hemangioma’ or ‘angioma’ in both Japan and Europe/the United States based on the impression that most anomalies are ‘tumors’. On the contrary, hemangioma simplex and cavernous hemangioma, for example, are actually morphological abnormalities of capillary blood vessels or veins, respectively, despite the disease name “hemangioma”. These diseases differ from tumors in a narrow sense, which refers to autonomous cell proliferation. In addition to such problems with disease naming and nomenclature, vascular lesions can occur at various ages and in various organs, meaning they may require treatment in various hospital departments, so improved common terms/language are essential for mutual understanding.
  • 467
  • 11 Mar 2022
Topic Review
Vascular and Cryptogam Flora on Bulgaria’s Ancient Mounds
The mounds are important for the preservation of the native vascular and cryptogam flora. A total of 1059 vascular plants, 58 bryophytes and 61 lichen taxa are recorded. Despite their small area, the mounds were shown to preserve nearly a quarter of the Bulgarian flora. The vegetation cover on the mounds included 61% perennials indicating a long-term persistence and stability. The majority (98%) of the established vascular plants were native species. 
  • 351
  • 18 Mar 2022
Topic Review
Vascular Alterations in Alzheimer’s Disease Brains
Alzheimer’s disease (AD) is the most common degenerative disorder in the elderly in developed countries. Growing evidence is pointing at endothelial dysfunction as a key player in the cognitive decline course of AD. As a main component of the blood–brain barrier (BBB), the dysfunction of endothelial cells driven by vascular risk factors associated with AD allows the passage of toxic substances to the cerebral parenchyma, producing chronic hypoperfusion that eventually causes an inflammatory and neurotoxic response.
  • 378
  • 06 Apr 2023
Topic Review
Vascular Aging
Vascular aging, i.e., the deterioration of the structure and function of the arteries over the life course, predicts cardiovascular events and mortality. Vascular degeneration can be recognized before becoming clinically symptomatic; therefore, its assessment allows the early identification of individuals at risk. This opens the possibility of minimizing disease progression. Vascular remodeling with advancing age is characterized by arterial stiffening and calcification. Arterial stiffening affects the macro- and micro-vasculature in unique ways. The main function of large arteries is to dampen the pulsatility of cardiac contraction by elastic recoiling after systolic expansion, so that constant, rather than pulsatile, blood flow is propelled to organs and tissues, including the coronary arteries.
  • 558
  • 06 Sep 2023
Topic Review
Vascular Access in Children with Short Bowel Syndrome
Short Bowel Syndrome and intestinal failure are chronic and severe conditions that may require life-long parenteral nutrition in children. Survival of these children relies on the correct functioning of central venous catheters; therefore, careful management, prevention, and treatment of complications is of paramount importance. Despite a growing awareness on preserving the vascular real estate, a certain number of patients still experience a progressive and life-threatening exhaustion of vascular access. 
  • 610
  • 31 May 2022
Biography
Varun Grover
Varun Grover (born 1959) is an American Information systems researcher, who is the David D. Glass Endowed Chair and Distinguished Professor at the Walton School of Business, University of Arkansas. From 2002-17, he was the William S. Lee (Duke Energy) Distinguished Professor of Information Systems at Clemson University, where he taught doctoral seminars on methods and information systems.[1] He
  • 407
  • 13 Dec 2022
Topic Review
VARTM Processed Composite Materials
Fiber-reinforced composite structures are used in different applications due to their excellent strength to weight ratio. Due to cost and tool handling issues in conventional manufacturing processes, like resin transfer molding (RTM) and autoclave, vacuum-assisted resin transfer molding (VARTM) is the best choice among industries. VARTM is highly productive and cheap. However, the VARTM process produces complex, lightweight, and bulky structures, suitable for mass and cost-effective production, but the presence of voids and fiber misalignment in the final processed composite influences its strength. Voids are the primary defects, and they cannot be eliminated completely, so a design without considering void defects will entail unreliability. Many conventional failure theories were used for composite design but did not consider the effect of voids defects, thus creating misleading failure characteristics.
  • 4.7K
  • 07 Apr 2021
Topic Review
Varnam
Varnam (meaning ‘colours’) is a social enterprise that has been working with artisans in Channapatna, Karnataka in India , for over 4 years. It has produced a series of designs interpreting this 200-year-old toy-making craft in the home and lifestyle, women's accessories space, giving tradition a contemporary twist. Using traditional lac-turnery methods popularised by the traditional Channapatna toys range, the label produces home and lifestyle products, toys and jewelry.
  • 517
  • 07 Nov 2022
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