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Topic Review
DNA-Based Artificial Transmembrane Channels for Biomedical Applications
Biomolecular channels on the cell membrane are essential for transporting substances across the membrane to maintain cell physiological activity. Artificial transmembrane channels used to mimic biological membrane channels can regulate intra/extracellular ionic and molecular homeostasis, and they elucidate cellular structures and functionalities. Due to their program design, facile preparation, and high biocompatibility, DNA nanostructures have been widely used as scaffolds for the design of artificial transmembrane channels and exploited for ionic and molecular transport and biomedical applications. DNA-based artificial channels can be designed from two structural modules: DNA nanotubes/nanopores as transport modules for mass transportation and hydrophobic segments as anchor modules for membrane immobilization. 
  • 147
  • 19 Mar 2024
Topic Review
Management of Insomnia in Menopausal Women
Insomnia is one of the major complaints of menopausal women with advancing age and may be complexly related to a variety of causes.
  • 166
  • 19 Mar 2024
Topic Review
Agricultural Produce Supply Chain Network of Capsicum
Vegetables are important for both nutritional and economic stability and contribute significantly to the agricultural landscape of India. The demand for vegetables is rising, driven by population growth and increased awareness of their benefits. 
  • 233
  • 19 Mar 2024
Topic Review
Functional Foods and Beverages with Promising Gut-Health-Related Outcomes
The notion of food as medicine can be traced back thousands of years, when the use of plants, herbs, and foods to treat disease and restore health was commonplace. Today, it is well understood that diet interacts with human physiology and health. Healthy dietary patterns that favour plant-based foods have been shown to offset the risk of chronic disease. Furthermore, components of plant-based diets have been shown to influence human physiology via effects on the gut microbiome. The innovation opportunity to design functional foods to support a resilient gut microbiota with a view to safeguarding against wider pathologies associated with gut dysbiosis extends the concept of functional foods into a new sphere. Bioactive food ingredients, through their interactions with the gut microbiota, may contribute to microbiota resilience, thus supporting the body’s adaptive capacity.
  • 83
  • 19 Mar 2024
Topic Review
Multi-View Stereo Method
As a 3D reconstruction method, multi-view stereoscopic (MVS) plays a vital role in 3D computer vision, and has a wide range of applications in the fields of virtual reality, augmented reality, and autonomous driving. With the rapid development of deep learning technology in the field of computer vision, the learning-based multi-view stereo method has produced advanced results.
  • 238
  • 18 Mar 2024
Topic Review
Role of Methionine Restriction in Gastric Cancer
Gastric cancer is ranked as the fifth most prevalent cancer globally and has long been a topic of passionate discussion among numerous individuals. However, the incidence of gastric cancer in society has not decreased, but instead has shown a gradual increase in recent years. For more than a decade, the treatment effect of gastric cancer has not been significantly improved. This is attributed to the heterogeneity of cancer, which makes popular targeted therapies ineffective. Methionine is an essential amino acid, and many studies have shown that it is involved in the development of gastric cancer. Our study aimed to review the literature on methionine and gastric cancer, describing its mechanism of action to show that tumor heterogeneity in gastric cancer does not hinder the effectiveness of methionine-restricted therapies. This research also aimed to provide insight into the inhibition of gastric cancer through metabolic reprogramming with methionine-restricted therapies, thereby demonstrating their potential as adjuvant treatments for gastric cancer.
  • 211
  • 18 Mar 2024
Topic Review
Giant Armadillo Optimization
A new bio-inspired metaheuristic algorithm called Giant Armadillo Optimization (GAO) is introduced, which imitates the natural behavior of giant armadillo in the wild. The fundamental inspiration in the design of GAO is derived from the hunting strategy of giant armadillos in moving towards prey positions and digging termite mounds.
  • 197
  • 18 Mar 2024
Topic Review
Micro-Grid Communication Protocols and Standards
A microgrid is a comprehensive system that includes energy storage, different energy sources, and loads within a certain boundary. It functions seamlessly, whether it is linked to, or works independently from, the main electrical grid, ensuring a consistent power supply. Microgrids consist of distributed energy resources (DER) and loads, which may be located in one place or spread throughout an electrical distribution network.
  • 476
  • 18 Mar 2024
Topic Review
Peripheral Arterial Atherosclerotic Disease in Elderly Patients
Atherosclerosis is a generalized and progressive disease. Ageing is a key risk factor for atherosclerosis progression that is associated with the increased incidence of ischemic events in supplied organs, including stroke, coronary events, limb ischemia, or renal failure. Cardiovascular disease is the leading cause of death and major disability in adults ≥ 75 years of age. Atherosclerotic occlusive disease affects everyday activity and quality of life, and it is associated with reduced life expectancy. Although there is evidence on coronary artery disease management in the elderly, there is insufficient data on the management in older patients presented with atherosclerotic lesions outside the coronary territory. Despite this, trials and observational studies systematically exclude older patients, particularly those with severe comorbidities, physical or cognitive dysfunctions, frailty, or residence in a nursing home. This results in serious critical gaps in knowledge and a lack of guidance on the appropriate medical treatment and referral for endovascular or surgical interventions. 
  • 113
  • 18 Mar 2024
Topic Review
Applications of Droplet Microsystems in Optics and Photonics
The micro- and nano-machining techniques applied to solid materials have yielded remarkable success in the semiconductor industry by integrating complex functionalities into microscale devices, thus spearheading the modern electronics revolution. Extending similar miniaturization strategies to process and assemble soft matter for creating multileveled functional structures over various length scales presents significant scientific and practical potential. Soft matter, including liquid crystals (LC), colloids, polymers, and biological substances, exhibits widespread influence across nature, living organisms, daily life, and industry. The biomimetic properties, responsiveness to stimuli, and efficacy in controlled release and sensing make soft matter extensively applicable in biology and chemistry.
  • 617
  • 18 Mar 2024
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