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Topic Review
In Vitro Growth of Human Follicles
Ovarian tissue cryopreservation is gaining importance as a successful method to restore fertility to girls and young women at high risk of sterility. However, there are concerns regarding the safety of transplantation after ovarian tissue cryopreservation due to the high risk of reintroducing cancer cells and causing disease recurrence. In these cases, the development of culture systems that support oocyte development from the primordial follicle stage is required.
  • 190
  • 19 Mar 2024
Topic Review
MicroRNAs as Potential Graft Rejection or Tolerance Biomarkers
Allograft rejection is a widespread complication in allograft recipients with chronic kidney disease. Undertreatment of subclinical and clinical rejection and later post-transplant problems are caused by an imperfect understanding of the mechanisms at play and a lack of adequate diagnostic tools. Many different biomarkers have been analyzed and proposed to detect and monitor these crucial events in transplant outcomes. In this sense, microRNAs may help diagnose rejection or tolerance and indicate appropriate treatment, especially in patients with chronic allograft rejection. As key epigenetic regulators of physiological homeostasis, microRNAs have therapeutic potential and may indicate allograft tolerance or rejection. However, more evidence and clinical validation are indispensable before microRNAs are ready for clinical prime time.
  • 84
  • 19 Mar 2024
Topic Review
Energy-Efficient Driving
The transportation sector remains a major contributor to greenhouse gas emissions. The understanding of energy-efficient driving behaviors and utilization of energy-efficient driving strategies are essential to reduce vehicles’ fuel consumption. However, there is no comprehensive investigation into energy-efficient driving behaviors and strategies. Furthermore, many state-of-the-art AI models have been applied for the analysis of eco-friendly driving styles, but no overview is available.
  • 147
  • 19 Mar 2024
Topic Review
Cultural Heritage of Montilla
The printing press was key for the dissemination of culture and knowledge in the Modern Age. It was used to produce books, documents, and etchings, which are key elements for the dissemination of knowledge and the preservation of human heritage.
  • 201
  • 19 Mar 2024
Topic Review
DNA-Based Artificial Transmembrane Channels for Biomedical Applications
Biomolecular channels on the cell membrane are essential for transporting substances across the membrane to maintain cell physiological activity. Artificial transmembrane channels used to mimic biological membrane channels can regulate intra/extracellular ionic and molecular homeostasis, and they elucidate cellular structures and functionalities. Due to their program design, facile preparation, and high biocompatibility, DNA nanostructures have been widely used as scaffolds for the design of artificial transmembrane channels and exploited for ionic and molecular transport and biomedical applications. DNA-based artificial channels can be designed from two structural modules: DNA nanotubes/nanopores as transport modules for mass transportation and hydrophobic segments as anchor modules for membrane immobilization. 
  • 147
  • 19 Mar 2024
Topic Review
Management of Insomnia in Menopausal Women
Insomnia is one of the major complaints of menopausal women with advancing age and may be complexly related to a variety of causes.
  • 166
  • 19 Mar 2024
Topic Review
Agricultural Produce Supply Chain Network of Capsicum
Vegetables are important for both nutritional and economic stability and contribute significantly to the agricultural landscape of India. The demand for vegetables is rising, driven by population growth and increased awareness of their benefits. 
  • 233
  • 19 Mar 2024
Topic Review
Functional Foods and Beverages with Promising Gut-Health-Related Outcomes
The notion of food as medicine can be traced back thousands of years, when the use of plants, herbs, and foods to treat disease and restore health was commonplace. Today, it is well understood that diet interacts with human physiology and health. Healthy dietary patterns that favour plant-based foods have been shown to offset the risk of chronic disease. Furthermore, components of plant-based diets have been shown to influence human physiology via effects on the gut microbiome. The innovation opportunity to design functional foods to support a resilient gut microbiota with a view to safeguarding against wider pathologies associated with gut dysbiosis extends the concept of functional foods into a new sphere. Bioactive food ingredients, through their interactions with the gut microbiota, may contribute to microbiota resilience, thus supporting the body’s adaptive capacity.
  • 83
  • 19 Mar 2024
Topic Review
Multi-View Stereo Method
As a 3D reconstruction method, multi-view stereoscopic (MVS) plays a vital role in 3D computer vision, and has a wide range of applications in the fields of virtual reality, augmented reality, and autonomous driving. With the rapid development of deep learning technology in the field of computer vision, the learning-based multi-view stereo method has produced advanced results.
  • 238
  • 18 Mar 2024
Topic Review
Role of Methionine Restriction in Gastric Cancer
Gastric cancer is ranked as the fifth most prevalent cancer globally and has long been a topic of passionate discussion among numerous individuals. However, the incidence of gastric cancer in society has not decreased, but instead has shown a gradual increase in recent years. For more than a decade, the treatment effect of gastric cancer has not been significantly improved. This is attributed to the heterogeneity of cancer, which makes popular targeted therapies ineffective. Methionine is an essential amino acid, and many studies have shown that it is involved in the development of gastric cancer. Our study aimed to review the literature on methionine and gastric cancer, describing its mechanism of action to show that tumor heterogeneity in gastric cancer does not hinder the effectiveness of methionine-restricted therapies. This research also aimed to provide insight into the inhibition of gastric cancer through metabolic reprogramming with methionine-restricted therapies, thereby demonstrating their potential as adjuvant treatments for gastric cancer.
  • 211
  • 18 Mar 2024
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