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Topic Review
Geography and Cartography in Medieval Islam
Medieval Islamic geography and cartography refer to the study of geography and cartography in the Muslim world during the Islamic Golden Age (variously dated between the 8th century and 16th century). Muslim scholars made advances to the mapmaking traditions of earlier cultures, particularly the Hellenistic geographers Ptolemy and Marinus of Tyre,:193 combined with what explorers and merchants learned in their travels across the Old World (Afro-Eurasia). Islamic geography had three major fields: exploration and navigation, physical geography, and cartography and mathematical geography. Islamic geography reached its apex with Muhammad al-Idrisi in the 12th century.
  • 2.6K
  • 26 Oct 2022
Topic Review
Atropa Belladonna
Atropa belladonna, commonly known as belladonna or deadly nightshade, is a toxic perennial herbaceous plant in the nightshade family Solanaceae, which also includes tomatoes, potatoes, and eggplant (aubergine). It is native to Europe, North Africa, and Western Asia. Its distribution extends from Great Britain in the west to western Ukraine and the Iranian province of Gilan in the east. It is also naturalised or introduced in some parts of Canada and the United States. The foliage and berries are extremely toxic when ingested, containing tropane alkaloids. These toxins include atropine, scopolamine, and hyoscyamine, which cause delirium and hallucinations, and are also used as pharmaceutical anticholinergics. Tropane alkaloids are of common occurrence not only in the Old World tribes Hyoscyameae (to which the genus Atropa belongs) and Mandragoreae, but also in the New World tribe Datureae - all of which belong to the subfamily Solanoideae of the plant family Solanaceae. Atropa belladonna has unpredictable effects. The antidote for belladonna poisoning is physostigmine or pilocarpine, the same as for atropine.
  • 2.6K
  • 25 Nov 2022
Topic Review
Ibrexafungerp
Ibrexafungerp is a first-in-class IV/oral triterpenoid antifungal agent. Similar in mechanism of action to echinocandins, ibrexafungerp inhibits (1→3)-β-D-glucan synthase, a key component of the fungal cell wall, resulting in fungicidal activity against Candida spp. Ibrexafungerp demonstrates broad in vitro activity against Candida spp.,Aspergillus spp., dimorphic fungi Pneumocystis and other emerging yeasts and mold pathogens including azole and echinocandin-resistant isolates. It is currently in late clinical development for treatment and prevention of vulvovaginal candidiasis. Other ongoing trials include treatment of serious fungal infections, including, invasive candidiasis, Candida auris infections, invasive aspergillosis and refractory fungal disease in patients not responding to or who are intolerant to standard of care .
  • 2.6K
  • 17 Mar 2021
Topic Review
BeiDou Navigation Satellite System
The BeiDou Navigation Satellite System (BDS) is a Chinese satellite navigation system. It consists of two separate satellite constellations. The first BeiDou system, officially called the BeiDou Satellite Navigation Experimental System and also known as BeiDou-1, consists of three satellites which since 2000 has offered limited coverage and navigation services, mainly for users in China and neighboring regions. Beidou-1 was decommissioned at the end of 2012. The second generation of the system, officially called the BeiDou Navigation Satellite System (BDS) and also known as COMPASS or BeiDou-2, became operational in China in December 2011 with a partial constellation of 10 satellites in orbit. Since December 2012, it has been offering services to customers in the Asia-Pacific region. In 2015, China started the build-up of the third generation BeiDou system (BeiDou-3) in the global coverage constellation. The first BDS-3 satellite was launched on 30 March 2015. As of January 2018, nine BeiDou-3 satellites have been launched. BeiDou-3 will eventually consist of 35 satellites and is expected to provide global services upon completion in 2020. When fully completed, BeiDou will provide an alternative global navigation satellite system to the United States owned Global Positioning System (GPS), and is expected to be more accurate than the GPS. It was claimed in 2016 that BeiDou-3 will reach millimeter-level accuracy (with post-processing), which is ten times more accurate than the finest level of GPS. According to China Daily, in 2015, fifteen years after the satellite system was launched, it was generating a turnover of $31.5 billion per annum for major companies such as China Aerospace Science and Industry Corp, AutoNavi Holdings Ltd, and China North Industries Group Corp.
  • 2.6K
  • 29 Nov 2022
Topic Review Peer Reviewed
Louis XI of Valois (1461–1483)
Louis XI (1461–1483) was the sixth king of the Valois branch of the Capetian dynasty in France; he ruled from 1463 until his death in 1483. Louis was the son of Charles VII (1403–1461) and Marie of Anjou (1404–1463). While Dauphin, he married first Margaret of Scotland (1424–1445) and then Charlotte of Savoie (c.1441–1483), who bore him four surviving children: Anne de France, Jeanne de France, François de France, and the future Charles VIII. Louis’ key challenge as monarch was to pick up the pieces of a kingdom ravaged by the Hundred Years War between England and France (1337–1453). His legacy was to have repaired the kingdom’s depleted coffers through a combination of frugality and territorial expansion. His historiography paints him as a paranoid, manipulative, and obsessively pious ruler, a simplistic portrait that is undermined by a close examination of his artistic patronage. This entry will focus on the iconography he employed across a variety of media to promote the sacred legitimacy of his rule and to unify the peoples of France’s newly acquired territories. 
  • 2.6K
  • 07 Jun 2022
Topic Review
CEO Power
In management research, CEO power refers to the power that can override objections to influence key decision outcomes within the company. This power can be obtained in formal or informal ways. 
  • 2.6K
  • 27 Aug 2021
Topic Review
Domain Fronting
Domain fronting is a technique for Internet censorship circumvention that uses different domain names in different communication layers of an HTTPS connection to discreetly connect to a different target domain than is discernable to third parties monitoring the requests and connections. Due to quirks in security certificates, the redirect systems of the content delivery networks (CDNs) used as 'domain fronts', and the protection provided by HTTPS, censors are typically unable to differentiate circumvention ("domain-fronted") traffic from overt non-fronted traffic for any given domain name. As such they are forced to either allow all traffic to the domain front—including circumvention traffic—or block the domain front entirely, which may result in expensive collateral damage and has been likened to "blocking the rest of the Internet".[note 1] Domain fronting does not conform to HTTP standards that require the SNI extension and HTTP Host header to contain the same domain. Large cloud service providers, including Amazon and Google, now actively prohibit domain fronting, which has made it "largely non-viable"[note 1] as a censorship bypass technique.
  • 2.6K
  • 06 Oct 2022
Topic Review
Drone Detection and Defense Systems
Drones are small and low-cost unmanned aerial vehicles (UAVs). With the decrease in the cost and size of drones in recent years, their number has also increased exponentially. As such, the concerns regarding security aspects that are raised by their presence are also becoming more serious.
  • 2.6K
  • 10 Mar 2022
Topic Review
Hole-Transporting Layer in Perovskite Solar Cells
Organic-inorganic halide perovskite solar cells (PSCs) have received particular attention because of the high-power conversion efficiencies (PCEs), facile fabrication route and low cost. The hole-transporting layer (HTL) play an important role in PSCs to effectively extract holes from the perovskite film and to transport holes to the metal electrode in normal PSCs. 
  • 2.6K
  • 09 Aug 2022
Topic Review
Ultra-Heat Treatment on Milk Proteins
Milk contains approximately 3.5% by weight protein, which is a highly complex system. This milk protein is usually divided into two main fractions based on their solubility nature. Casein proteins are about 75% to 80% of the total protein in the milk and precipitate at pH 4.6 at 20 °C, while 20% of the protein remains in the serum.
  • 2.6K
  • 07 Oct 2021
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