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Topic Review
Activity of Kalanchoe pinnata in Cancer
Kalanchoe pinnata (Lam) Pers. (syn. Bryophyllum pinnatum Lam.), belonging to the genus Kalanchoe, is a succulent plant cultivated in gardens, which can be found as a herb or shrub. The bioactive ingredients in Kalanchoe pinnata, a succulent herb with ethnomedical applications for several diseases, including cancer, and reveal its anticancer mechanisms through a molecular approach.
  • 2.8K
  • 17 Oct 2022
Topic Review
Urban Land Use Planning
Urbanization is persistent globally and has increasingly significant spatial and environmental consequences. It is especially challenging in developing countries due to the increasing pressure on the limited resources, and damage to the bio-physical environment.
  • 2.8K
  • 13 Oct 2021
Topic Review
Naturopathy
Naturopathy, or naturopathic medicine, is a form of alternative medicine. It employs an array of pseudoscientific practices branded as "natural", "non-invasive", or promoting "self-healing". The practices of naturopaths, the practitioners of naturopathic medicine, vary widely and are difficult to generalize. Treatments range from outright quackery, like homeopathy, to widely accepted practices like psychotherapy. The ideology and methods of naturopathy are based on vitalism and folk medicine rather than evidence-based medicine (EBM), although some practitioners may use techniques supported by EBM. Naturopathic practitioners commonly recommend against following modern medical practices, including but not limited to medical testing, drugs, vaccinations, and surgery. Instead, naturopathic practice relies on unscientific notions, often leading naturopaths to diagnoses and treatments that have no factual merit. Naturopathy is considered by the medical profession to be ineffective and harmful, raising ethical issues about its practice. In addition to condemnations and criticism from the medical community, such as the American Cancer Society, naturopaths have repeatedly been denounced as and accused of being charlatans and practicing quackery. Naturopaths are known for their frequent campaigning for legal recognition in the United States . It is illegal in two U.S. states and tightly regulated in many others. Some states have lax regulations, however, and may allow naturopaths to perform minor surgery or even prescribe drugs. While some schools exist for naturopaths, and some jurisdictions allow such practitioners to call themselves doctors, the lack of accreditation and scientific medical training means they lack the competency of true medical doctors.
  • 2.8K
  • 24 Oct 2022
Topic Review
Lalitaditya Muktapida of Kashmir
Lalitaditya Muktapida of Kashmir, an eminent 8th-century ruler, is a significant yet often overlooked figure in Indian history. Known for his unparalleled military prowess, Lalitaditya never lost a battle, whether against the Arabs or his contemporaries. Beyond his martial achievements, he was a prolific builder, responsible for the construction of numerous cities and monumental structures, including the grand Martand Sun Temple and his capital, Parihaspura. His reign in Kashmir was characterised by wide territorial control and cultural flowering.
  • 2.8K
  • 02 Jul 2024
Topic Review
Acronis True Image
Acronis True Image is a software product produced by Acronis that provides data protection for personal users including, backup, archive, access and recovery for Windows, macOS, iOS, and Android operating systems. As disk imaging software, True Image can restore the previously captured image to another disk, replicating the structure and contents to the new disk, also allowing disk cloning and partition resizing, even if the new disk is of a different capacity. The backups are in a proprietary format which saves using a .tib filename format. Acronis was launched in 2003 and in December 2014 claimed to have over 5 million consumer and 500,000 businesses users.
  • 2.8K
  • 15 Nov 2022
Topic Review
Lagrangian Point
In celestial mechanics, the Lagrangian points (/ləˈɡrɑːndʒiən/ also Lagrange points, L-points, or libration points) are the points near two large bodies in orbit where a smaller object will maintain its position relative to the large orbiting bodies. At other locations, a small object would go into its own orbit around one of the large bodies, but at the Lagrangian points the gravitational forces of the two large bodies, the centripetal force of orbital motion, and (for certain points) the Coriolis acceleration all match up in a way that cause the small object to maintain a stable or nearly stable position relative to the large bodies. There are five such points, labeled L1 to L5, all in the orbital plane of the two large bodies, for each given combination of two orbital bodies. For instance, there are five Lagrangian points L1 to L5 for the Sun–Earth system, and in a similar way there are five different Lagrangian points for the Earth–Moon system. L1, L2, and L3 are on the line through the centers of the two large bodies, while L4 and L5 each act as the third vertex of an equilateral triangle formed with the centers of the two large bodies. L4 and L5 are stable, which implies that objects can orbit around them in a rotating coordinate system tied to the two large bodies. Several planets have trojan satellites near their L4 and L5 points with respect to the Sun. Jupiter has more than a million of these trojans. Artificial satellites have been placed at L1 and L2 with respect to the Sun and Earth, and with respect to the Earth and the Moon. The Lagrangian points have been proposed for uses in space exploration.
  • 2.8K
  • 17 Nov 2022
Topic Review
CO2 Activation on Catalyst Surfaces
Utilizing CO2 as a sustainable carbon source to form valuable products requires activating it by active sites on catalyst surfaces. These active sites are usually in or below the nanometer scale. Some metals and metal oxides in this scale dimension can catalyze the CO2 transformation reactions. Herein, CO2 activation on metal-based catalyst surfaces and how their structures impact the activation process are highlighted.
  • 2.8K
  • 13 Dec 2021
Topic Review
List of Oldest Surviving Ships
This is a list of the oldest ships in the world which have survived to this day without significantly losing their original form. It includes warships, yachts, tall ships, and vessels recovered during archaeological excavations. It does not include reconstructions or replicas, partially complete wreckage, or ships which have been located but remain underwater. For example, the Mary Rose, whose remains consist only of a partial hull, is not included here. Vessels listed are sorted by date of launching as most accurately known.
  • 2.8K
  • 07 Nov 2022
Topic Review
Stereolithography
Being the earliest form of Additive manufacturing, Stereolithography (SLA) fabricates 3D objects by selectively solidifying the liquid resin through photopolymerization reaction. The ability to fabricate objects with high accuracy as well as a wide variety of materials brings much attention to stereolithography. Since its invention in 1980s, SLA underwent four generations of major technological innovation over the past 40 years. These innovations have thus result in a diversifies range of stereolithography systems with dramatically improved resolution, throughput, and materials selection for creating complex 3D objects and devices. In this paper, we review the four generations stereolithography processes, which are scanning, projection, continuous and volumetric stereolithography. For each generation, representative stereolithography system configurations are also discussed in detail. In addition, other derivative technologies, such as scanning-projection, multi-material, and magnetically assisted stereolithography processes, are also included in this review.
  • 2.8K
  • 16 Sep 2020
Topic Review
Stress
Stress, either physiological, biological or psychological, is an organism's response to a stressor such as an environmental condition. Stress is the body's method of reacting to a condition such as a threat, challenge or physical and psychological barrier. There are two hormones that an individual produces during a stressful situation, these are well known as adrenaline and cortisol. Stimuli that alter an organism's environment are responded to by multiple systems in the body. In humans and most mammals, the autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis are the two major systems that respond to stress. The sympathoadrenal medullary (SAM) axis may activate the fight-or-flight response through the sympathetic nervous system, which dedicates energy to more relevant bodily systems to acute adaptation to stress, while the parasympathetic nervous system returadrenaliney to homeostasis. The second major physiological stress-response center, the HPA axis, regulates the release of cortisol, which influences many bodily functions such as metabolic, psychological and immunological functions. The SAM and HPA axes are regulated by several brain regions, including the limbic system, prefrontal cortex, amygdala, hypothalamus, and stria terminalis. Through these mechanisms, stress can alter memory functions, reward, immune function, metabolism and susceptibility to diseases. Disease risk is particularly pertinent to mental illnesses, whereby chronic or severe stress remains a common risk factor for several mental illnesses. One system suggests there are five types of stress labeled "acute time-limited stressors", "brief naturalistic stressors", "stressful event sequences", "chronic stressors", and "distant stressors". An acute time-limited stressor involves a short-term challenge, while a brief natural stressor involves an event that is normal but nevertheless challenging. A stressful event sequence is a stressor that occurs, and then continues to yield stress into the immediate future. A chronic stressor involves exposure to a long-term stressor, and a distant stressor is a stressor that is not immediate.
  • 2.8K
  • 28 Oct 2022
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