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Topic Review
Glutamatergic System in Depression
Major depressive disorder (MDD) is a heterogeneous neuropsychological disorder characterized by a combination of symptoms that negatively impact the productivity and well-being of inflicted patients, including impairments in cognition, emotional regulation, memory, motor function, motivation, and possible suicidal ideation. Glutamate is the major excitatory neurotransmitter in the central nervous system. It plays an important role in several physiological functions.
  • 2.8K
  • 11 May 2022
Topic Review
Austenite Stability
The austenite stability represents the potential of metastable austenite grains in resisting the martensitic phase transformation under an applied either thermal or mechanical driving force. 
  • 2.8K
  • 18 Aug 2020
Topic Review
West African Lion
The West African lion is a Panthera leo leo population in West Africa. It is listed as Critically Endangered on the IUCN Red List. This population is isolated and probably comprises fewer than 250 mature individuals. Already in 2004, the lion population in West and Central Africa was fragmented and estimated as comprising at most 1,800 individuals. The West African lion was formerly considered a distinct lion subspecies with the scientific name P. l. senegalensis. Results of phylogenetic research indicate that the West African lion population forms a distinct clade and is closely related to Central African, North African and Asian lion populations. The lion populations in North, West and Central Africa and Asia were therefore subsumed to P. l. leo in 2017.
  • 2.8K
  • 17 Oct 2022
Topic Review
Bio-Signals in Medical Applications
Artificial Intelligence (AI) has broadly connected the medical field at various levels of diagnosis based on the congruous data generated. Different types of bio-signal can be used to monitor a patient’s condition and in decision making. Medical equipment uses signals to communicate information to care staff. AI algorithms and approaches will help to predict health problems and check the health status of organs, while AI prediction, classification, and regression algorithms are helping the medical industry to protect from health hazards. The early prediction and detection of health conditions will guide people to stay healthy.
  • 2.8K
  • 03 Mar 2022
Topic Review
Ghazal
The ghazal (Bengali: গজল, Sylheti: ꠊꠏꠟ, Punjabi: ਗ਼ਜ਼ਲ, Urdu: غزَل , Hindi: ग़ज़ल, Persian: غزل‎, Azerbaijani: qəzəl, Turkish: gazel, Uzbek: gʻazal, Pashto: غزل‎, Template:Lang-gu,) is a form of amatory poem or ode, originating in Arabic poetry. A ghazal may be understood as a poetic expression of both the pain of loss or separation and the beauty of love in spite of that pain. The ghazal form is ancient, tracing its origins to 7th-century Arabic poetry. The ghazal spread into South Asia in the 12th century due to the influence of Sufi mystics and the courts of the new Islamic Sultanate, and is now most prominently a form of poetry of many languages of the Indian subcontinent and Turkey. A ghazal commonly consists of between five and fifteen couplets, which are independent, but are linked – abstractly, in their theme; and more strictly in their poetic form. The structural requirements of the ghazal are similar in stringency to those of the Petrarchan sonnet. In style and content, due to its highly allusive nature, the ghazal has proved capable of an extraordinary variety of expression around its central themes of love and separation.
  • 2.8K
  • 24 Nov 2022
Topic Review
Research on COVID-19
As of March, most of the world is under the order of a “lockdown” or “restricted movement control” whereby world leaders and medical experts believe that social isolation is the best option at reducing the spread of the highly infectious and novel disease, that is Coronavirus Disease (COVID-19). While this preventive measure is in place, various diagnostic kits and treatment strategies are being researched daily to diagnose and curb this disease quickly. This report summarizes the characteristics of the SARS-CoV-2 virus and evaluates the diagnostic kits and treatment drugs as well as vaccines that are either currently being used (RT-PCR) or in the clinical pipeline for safety and efficacy testing, respectively. The sooner efficient diagnosis and treatment can be made, the greater the number of lives will be saved.
  • 2.8K
  • 30 Oct 2020
Topic Review
Swissindo World Trust International Orbit
This article is about a new religious movement in Indonesia. For more information regarding religion in Indonesia, see Religion in Indonesia. Swissindo World Trust International Orbit is a religious movement established in 2010 concerned with eliminating the debt of every individual on Earth. It originated in West Java, Indonesia and is led by Sino Soegihartonotonegoro. The organisation has members from a vast array of nations including the United States , Australia and the Netherlands. Due to its illegal financial practices, the Cirebon office of the Financial Services Authority has conducted an investigation into Swissindo. The organisation has been criticised for targeting poor and marginalised communities. Swissindo asserts its mission is to create “Heaven on Earth” through various means.
  • 2.8K
  • 16 Nov 2022
Topic Review
Maize/Sorghum as Raw Brewing Materials
Brewing is among the oldest biotechnological processes, in which barley malt and—to a lesser extent—wheat malt are used as conventional raw materials. Other cereals as corn and sorghum could also be used in  brewing.
  • 2.8K
  • 06 May 2021
Topic Review
Plants as anti-inflammatory drugs
Plants represent the main source of molecules for the development of new drugs, which intensifies the interest of transnational industries in searching for substances obtained from plant sources, especially since the vast majority of species have not yet been studied chemically or biologically, particularly concerning anti-inflammatory action. Anti-inflammatory drugs can interfere in the pathophysiological process of inflammation, to minimize tissue damage and provide greater comfort to the patient. Therefore, it is important to note that due to the existence of a large number of species available for research, the successful development of new naturally occurring anti-inflammatory drugs depends mainly on a multidisciplinary effort to find new molecules. Although many review articles have been published in this regard, the majority presented the subject from a limited regional perspective.
  • 2.8K
  • 25 Aug 2020
Topic Review
Salt Bridges investigated by NMR
Salt bridges are interactions, electrostatic combined with hydrogen bonding, between oppositely charged residues, typically carboxylic acid anions and ammonium ions, provided they are close together.  For an illustration see Fig. 1. Salt bridges are of particular interest in proteins and other biomolecules.  In the present contribution salt bridges are investigated by means of 1H chemical shifts, determination of pKa values and deuterium isotope effect on 15N and 1H chemical shifts.  In the latter case model compounds like ammonium ions are also investigated and the use of deuterium isotope effects on chemical shifts are supported by Density Functional Theory (DFT) calculations.  The use of isotope effects on chemical shifts enables a distinction between salt bridges observed in the solid state by X-ray diffraction and those actually present in solution.
  • 2.8K
  • 27 Oct 2020
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