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Topic Review
Muscle Tone Physiology
The simple definition of tone as the resistance to passive stretch is physiologically a complex interlaced network encompassing neural circuits in the brain, spinal cord, and muscle spindle. Disorders of muscle tone can arise from dysfunction in these pathways and manifest as hypertonia or hypotonia. The loss of supraspinal control mechanisms gives rise to hypertonia, resulting in spasticity or rigidity. On the other hand, dystonia and paratonia also manifest as abnormalities of muscle tone, but arise more due to the network dysfunction between the basal ganglia and the thalamo-cerebello-cortical connections. 
  • 3.0K
  • 19 May 2021
Topic Review
Pelagic Zone
The pelagic zone consists of the water column of the open ocean, and can be further divided into regions by depth (as illustrated on the right). The word pelagic is derived from grc πέλαγος (pélagos) 'open sea'. The pelagic zone can be thought of as an imaginary cylinder or water column between the surface of the sea and the bottom. Conditions in the water column change with depth: pressure increases; temperature and light decrease; salinity, oxygen, micronutrients (such as iron, magnesium and calcium) all change. Marine life is affected by bathymetry (underwater topography) such as the seafloor, shoreline, or a submarine seamount, as well as by proximity to the boundary between the ocean and the atmosphere at the ocean surface, which brings light for photosynthesis, predation from above, and wind stirring up waves and setting currents in motion. The pelagic zone refers to the open, free waters away from the shore, where marine life can swim freely in any direction unhindered by topographical constraints. The oceanic zone is the deep open ocean beyond the continental shelf, which contrasts with the inshore waters near the coast, such as in estuaries or on the continental shelf. Waters in the oceanic zone plunge to the depths of the abyssopelagic and further to the hadopelagic. Coastal waters are generally the relatively shallow epipelagic. Altogether, the pelagic zone occupies 1,330 million km3 (320 million mi3) with a mean depth of 3.68 km (2.29 mi) and maximum depth of 11 km (6.8 mi). Pelagic life decreases as depth increases. The pelagic zone contrasts with the benthic and demersal zones at the bottom of the sea. The benthic zone is the ecological region at the very bottom, including the sediment surface and some subsurface layers. Marine organisms such as clams and crabs living in this zone are called benthos. Just above the benthic zone is the demersal zone. Demersal fish can be divided into benthic fish, which are denser than water and rest on the bottom, and benthopelagic fish, which swim just above the bottom. Demersal fish are also known as bottom feeders and groundfish.
  • 3.0K
  • 14 Nov 2022
Topic Review
Holika
Holika (Sanskrit: होलिका) was a demoness in Hindu Vedic scriptures, who was burnt to death with the help of God Vishnu. She was the sister of King Hiranyakashipu and aunt of Prahlad. The story of Holika Dahan (Holika's death) signifies the triumph of good over evil. Holika is associated with the annual bonfire on the night before Holi, the Hindu festival of colors.
  • 3.0K
  • 29 Nov 2022
Topic Review
Electromyography
Electromyography (EMG) is a bioelectrical signal to assess electrical activity produced by skeletal muscles. In the study of muscle fatigue, the electrophysiological measurement of muscles play a crucial role in collecting electrical signals from skeletal muscles. Since EMG signals usually contain a certain amount of noise, it is essential to obtain high quality data in the early stage. In addition, people prefer a painless and comfortable method when recording muscle contraction signals.  This review addresses the EMG data collection methods with good quality and less pain, their applications, and the examples of actual EMG data analysis.
  • 3.0K
  • 20 Feb 2021
Topic Review
Myeloid-Derived Suppressor Cells
Myeloid-derived suppressor cells (MDSCs) are heterogeneous cells derived from bone marrow. They are precursors of dendritic cells, macrophages and/or granulocytes. They have the ability to significantly inhibit immune cell responses.
  • 3.0K
  • 27 Oct 2020
Topic Review
Idolatry in Sikhism
Sikhism prohibits idolatry, in accordance with mainstream Khalsa norms and the teachings of the Sikh Gurus, a position that has been accepted as orthodox. Growing Sikh popular discontent with Gurdwara administration and practices during the 1800s, revivalist movements in the mid-1800s who opposed idol worship like the Nirankaris and the Namdharis (who however have followed a living guru since its inception), and the encroachment of Brahmanical customs in the Golden Temple during that period, led to the establishment of the Singh Sabha Movement in 1873, in which the Tat Khalsa faction, dominant since the early 1880s, pushed to renew and standardize the practice of Sikhism. After a period of political advancement, the Khalsa faction re-established direct control over Gurdwara management over the Udasi and Hindu mahants, who institutionalized idol worship and would eventually identify with the Sanatan Sikhs, who identified with the Brahmanical social structure and considered idol worship as not harmful. The mahants had gained control of Gurdwaras after heavy Mughal persecution forced the Khalsa to relinquish control of the Gurdwaras and vacate the Punjab plains in the 1700s; they were most prominent in the 1800s. The Arya Samaj, opponents of the Sikhs, asserted that many Sikhs accepted idols and their worship within Sikh temples, unlike Khalsa Sikhs who strongly opposed the practice. In 1905, after re-establishing institutional control, the Khalsa managed to have removed the idols installed during the preceding period, as well as ending mahant administration and the practice of other non-Sikh, Brahmanical rituals in the process, considering them "Hindu accretions" and "Brahmanical stranglehold," amidst a major controversy within the Sikh community of that era. The prohibition, state Fenech and McLeod, has also served a means to assert Sikhism differs from Hinduism.
  • 3.0K
  • 04 Nov 2022
Topic Review
Green Chemistry Education
An important goal for sustainability education is to learn negotiation, problem solving and decision-making skills through discussions about ecological, social, economic, and ethical principles concerning local and global responsibility in their own life. Through memorable, experiential, and active processes, students learn to discuss their own value selection and to evaluate phenomena and sources of information critically. In this article, we aim to identify suitable pedagogical approaches to teaching and learning green chemistry among college students and preservice teachers by examining the teaching methods that have been used to promote green chemistry education (GCE) and how these methods have supported green chemistry learning (GCL).
  • 3.0K
  • 11 Nov 2020
Topic Review
Power Electronics for Distributed Generation
Power electronics is formed by technologies that, through advanced controls of semiconductor devices, efficiently convert electrical energy for appropriate use in many areas. Distributed generation (DG), mainly renewable energy, is a group of power sources that can be installed in distinct points of the power system or be isolated, such as: wind power, photovoltaic systems, fuel cells, small hydro, and microturbines. Power converters are a crucial technology for the integration of DG into the modern sustainable power system, including microgrids and smart grids structures. They allow correct adaptation, but also enable DG units to fully realize their potential benefits in their wide variety of configurations.
  • 3.0K
  • 23 Mar 2022
Topic Review
Lysyl oxidase like 2
LOXL2 is a key enzyme that catalyzes the cross-linking of collagen fibers and forms an integral part in collagen homeostasis. It is thus needed for normal functioning of the myocardium and is pertinent to cardiac remodeling [13]. Dysregulation of its expression is a major driver of muscle stiffness through induced cardiac fibrosis [24,25,43], which reduces cardiac output. In fact, it has been proposed that decreasing excessive collagen cross-linking would reduce myocardial fibrosis and stiffness and thereby improve heart function [44].
  • 3.0K
  • 20 Aug 2020
Topic Review
Dewi Sri
Dewi Sri or Shridevi (Javanese: ꦢꦺꦮꦶꦱꦿꦶ), Dewi Sri) (Sundanese: Nyai Pohaci Sanghyang Asri) is the Javanese, Sundanese, and Balinese Hindu Goddess of rice and fertility, still widely worshiped on the islands of Java, Bali and Lombok, Indonesia. The cult of the rice goddess has its origin in the prehistoric domestication, development and propagation of rice cultivation in Asia, possibly brought by Austroasiatic or Austronesian population that finally migrated and settled in the archipelago. Similar but slightly different rice spirits mythologies are widespread among Indonesian ethnicities and also neighboring countries. The mythology of Dewi Sri is native to Java and Sunda and Hinduism in the archipelago since early as the first century. She was equated with the Hindu goddess Shri Lakshmi, and often regarded as an incarnation or one of her manifestations. The goddess is also associated with wealth and prosperity.
  • 3.0K
  • 11 Oct 2022
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