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Topic Review
Afro-Ethnic Hairstyling Trends, Risks, Recommendations
Hair is an essential part of a person’s identity, self-perception, and can be a way they communicate with those around them. It can reflect not only someone’s health but their sense of style, and can be changed often and easily to portray an individual’s changing attitudes and trends. Hairstyles among women of African descent, thus, vary considerably by country, region, occupation, generation, and personal style. Today, the Black hair care industry is a half-trillion-dollar industry. In fact, Black women spend more on their hair than any other ethnic group. There has been substantial debate and discussion regarding the association between certain hairstyles worn by Black women and their connection to hair disorders and other health conditions common to this population.
  • 512
  • 18 Feb 2022
Topic Review
Plant-Based Diets effects on Skin Diseases
A plant-based diet refers to a way of eating that primarily focuses on consuming foods derived from plants. This includes a wide variety of vegetables, fruits, beans, lentils, legumes, nuts, seeds, fungi, and whole grains. Animal products and processed foods are limited or avoided in this dietary approach. Plant-based diets have been found to have benefits for various conditions and diseases and specific plant-based functional foods can play a role in supporting skin health. One of the targets of this dietary pattern is the gut microbiota, the community of microorganisms residing in our digestive system. Improving the health of the gut microbiota may contribute to some of the positive effects observed on overall health, including the skin. By adopting a plant-based diet, individuals can provide their bodies with a rich array of nutrients, antioxidants, and fiber that are abundant in plant foods. These components can support overall health and may have a positive impact on the condition of the skin. However, it's important to note that individual results may vary, and maintaining a balanced diet, as well as considering other factors like skincare routines and overall lifestyle, is essential for optimal skin health.
  • 510
  • 10 Jul 2023
Topic Review
Wound-Microenvironment Engineering
In patients with comorbidities, a large number of wounds become chronic, representing an overwhelming economic burden for healthcare systems. Engineering the microenvironment is a paramount trend to activate cells and burst-healing mechanisms. The extrusion bioprinting of advanced dressings was performed with novel composite bioinks made by blending adipose decellularized extracellular matrix with plasma and human dermal fibroblasts. Rheological and microstructural assessments of the composite hydrogels supported post-printing cell viability and proliferation over time.
  • 508
  • 16 Mar 2022
Topic Review
Cutaneous Squamous Cell Carcinoma in Epidermolysis Bullosa
Inherited epidermolysis bullosa (EB) is a complex clinical and pathological entity that includes over 30 phenotypically and/or genotypically distinct inherited diseases, all sharing an intrinsic common tendency toward mechanical skin fragility and bullae formation. Based on cleavage level, four major types of inherited EB have been described: EB simplex (EBS), junctional EB (JEB), dystrophic EB (DEB), and Kindler syndrome (KS). Therefore, intraepidermal blistering is the most characteristic feature of EBS, while in JEB and DEB blisters arise from the lamina lucida and the sub-lamina densa, respectively. On the other hand, in KS, multiple cleavage planes have been described and may be present at the same time in the same patient.
  • 508
  • 26 Apr 2022
Topic Review
Skin Conditions during COVID-19 Era
The most frequent inflammatory skin diseases are psoriasis, atopic dermatitis, hidradenitis suppurativa, and acne. Their management is challenging for dermatologists since their relapsing chronic clinical course is associated with a great impact on quality of life.
  • 504
  • 16 Mar 2022
Topic Review
The Pathogenesis of Alopecia Areata
Alopecia areata is a multifactorial autoimmune-based disease with a complex pathogenesis. As in all autoimmune diseases, genetic predisposition is key. The collapse of the immune privilege of the hair follicle leading to scalp loss is a major pathogenic event in alopecia areata. The microbiota considered a bacterial ecosystem located in a specific area of the human body could somehow influence the pathogenesis of alopecia areata, as it occurs in other autoimmune diseases. Moreover, the Next Generation Sequencing of the 16S rRNA bacterial gene and the metagenomic methodology have provided an excellent characterization of the microbiota.
  • 500
  • 04 Nov 2022
Topic Review
Genetics of Female Pattern Hair Loss
Pattern hair loss can occur in both men and women, and the underlying molecular mechanisms have been continuously studied in recent years. Male androgenetic alopecia (M-AGA), also termed male pattern hair loss, is the most common type of hair loss in men. M-AGA is considered an androgen-dependent trait with a background of genetic predisposition.
  • 497
  • 04 Jul 2023
Topic Review
Metabolomics in Atopic Eczema
Atopic eczema (AE) is an inflammatory skin disorder affecting approximately 20% of children worldwide and early onset can lead to asthma and allergies. Metabolomics, the analysis of small molecules in the skin produced by the host and microbes, opens a window to observe the mechanisms of the disease which then may lead to new drug targets for AE treatment. 
  • 494
  • 27 Sep 2022
Topic Review
House Dust Mite Allergy
The house dust mite (HDM) is globally ubiquitous in human habitats. The present entry summarizes information about the role of Der p 1 as key coordinator of the HDM-induced allergic response and reports a series of Italian patients allergic to HDM. Our study offers insights into the role of Der p groups in a population of patients with allergic rhinitis and asthma who were candidate for ITS. Interestingly, Der p1 positivity was associated with bronchial asthma and co-sensitization.
  • 492
  • 27 Apr 2021
Topic Review
Influence of Sleep and Western Diet in Psoriasis
The World Health Organization (WHO) reports psoriasis (PsO) as one of the five diseases that drastically influence patients’ quality of life. PsO is a systemic, chronic inflammatory skin disease related to epidermal keratinocyte hyperplasia and epidermal immune cell over-activation via the interleukin (IL)-23/IL-17 axis. It is one of the most common chronic inflammatory skin diseases, with a prevalence of 1–2% worldwide, and almost 6–11% of patients with PsO may have inflammatory arthropathy (psoriatic arthritis). 
  • 491
  • 21 Oct 2022
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