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Topic Review
Digital Removable Dentures
Digital dentistry, an offspring of digital technology and robotics that emerged in the 1980s, has revolutionized various aspects of dental practice, including the creation of CDs. Computer-aided design and computer-aided manufacturing (CAD/CAM) techniques have been used for crafting CDs. The application of CAD/CAM methods in CD fabrication has attracted considerable attention, driving advancements in both design and production, promising quicker and higher-quality outcomes
  • 122
  • 11 Jan 2024
Topic Review
Hydrogen in Transplantation
Hydrogen gas, renowned for its antioxidant properties, has emerged as a novel therapeutic agent with applications across various medical domains, positioning it as a potential adjunct therapy in transplantation. 
  • 187
  • 11 Jan 2024
Topic Review
Kirsten Rat Sarcoma Virus Detection
Non-small-cell lung cancer (NSCLC) is a prevalent and often fatal malignancy. Kirsten rat sarcoma virus (KRAS) is a commonly mutated oncogene in NSCLC, contributing to tumorigenesis and proliferation.
  • 70
  • 11 Jan 2024
Topic Review
Approaches for Atrial Fibrillation Detection
Atrial Fibrillation (AFib) is a Cardiovascular Disease (CVD) characterized by the uncoordinated activity of the heart chambers, with the atria exhibiting irregular and high-rate electrical activity. Autoencoders (AEs) can be used as an automatic feature extraction tool, tailoring the resulting features to a specific classification task. By coupling an encoder to a classifier, it is possible to reduce the dimension of the Electrocardiogram (ECG) heartbeat waveforms and classify them. 
  • 85
  • 11 Jan 2024
Topic Review
Pregnancy, Breastfeeding, and Vitamin D
Vitamin D metabolism manifests significant changes in pregnant women in comparison to the non-pregnant state, but several questions about the role of vitamin D in pregnancy remain unanswered. Vitamin D deficiency has been reported among pregnant women and nursing mothers globally, constituting a risk group for vitamin D deficiency. Vitamin D deficiency during pregnancy has been associated not only with pregnancy outcomes but also with the posterior physical and mental health of the offspring.
  • 96
  • 11 Jan 2024
Topic Review
The Role of Magnesium in Muscle Health
Magnesium is an essential mineral that plays a central role in approximately 800 biochemical reactions within the human body. Its distinctive physical and chemical attributes render it an indispensable stabilizing factor in the orchestration of diverse cellular reactions and organelle functions, thereby rendering it irreplaceable in processes directly impacting muscle health.
  • 167
  • 11 Jan 2024
Topic Review
Multimodality Imaging Diagnosis in Infective Endocarditis
Imaging is an important tool in the diagnosis and management of infective endocarditis (IE). Echocardiography is an essential examination, especially in native valve endocarditis (NVE), but its diagnostic accuracy is reduced in prosthetic valve endocarditis (PVE). The diagnostic ability is superior for transoesophageal echocardiography (TEE), but a negative test cannot exclude PVE. Both transthoracic echocardiography (TTE) and TEE can provide normal or inconclusive findings in up to 30% of cases, especially in patients with prosthetic devices.
  • 127
  • 11 Jan 2024
Topic Review Video
Acetaminophen and Neurodevelopment
Based on available data that include approximately 20 lines of evidence from studies in laboratory animal models, observations in humans, correlations in time, and pharmacological/toxicological considerations, it has been concluded without reasonable doubt and with no evidence to the contrary that exposure of susceptible babies and children to acetaminophen (paracetamol) induces many, if not most, cases of autism spectrum disorder (ASD).
  • 173
  • 11 Jan 2024
Topic Review
Anterior Skull Base Reconstruction Using the Nasoseptal Flap
The nasoseptal flap (NSF) has become a workhorse reconstructive option in the endonasal repair of anterior skull base defects. The flap is pedicled on the posterior septal nasal artery, which branches off the sphenopalatine artery and courses along the posterior nasal cavity and inferior sphenoid face. Due to its versatile nature and customizability, the NSF can be utilized for a range of different defects extending from the frontal recess to the low clivus in the sagittal plane. 
  • 170
  • 11 Jan 2024
Topic Review
Treatment of Heart Failure with Preserved Ejection Fraction
Heart failure is a clinical syndrome associated with poor quality of life, substantial healthcare resource utilization, and premature mortality, in large part related to high rates of hospitalizations. The clinical manifestations of heart failure are similar regardless of the ejection fraction. Unlike heart failure with reduced ejection fraction, there are few therapeutic options for treating heart failure with preserved ejection fraction. Molecular therapies that have shown reduced mortality and morbidity in heart failure with reduced ejection have not been proven to be effective for patients with heart failure and preserved ejection fraction. The study of pathophysiological processes involved in the production of heart failure with preserved ejection fraction is the basis for identifying new therapeutic means.
  • 181
  • 11 Jan 2024
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