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All Topic Review Biography
Topic Review
Treatment Algorithm for Cancerous Wounds
Cancerous wound can be defined as non-healing compound chronic painful wound that arises from cancers and due to increased necrosis and infection, the quantity of malodorous discharge is highly increased. In advanced cancer stage the incidence of cancerous wounds is about 5%, and the estimated life expectancy is not more than 6 to 12 months. 
  • 3.8K
  • 11 Mar 2022
Topic Review
Treatment Advances in Sepsis and Septic Shock
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, and it affects over 25 million people every year. Even more severe, septic shock is a subset of sepsis defined by persistent hypotension, and hospital mortality rates are higher than 40%. As new pathophysiological mechanisms have been uncovered, immunostimulatory therapy has emerged as a promising path forward. Highly investigated treatment strategies include cytokines and growth factors, immune checkpoint inhibitors, and even cellular therapies.
  • 306
  • 04 May 2023
Topic Review
Treating Traumatic Brain Injuries
Traumatic brain injury (TBI) is defined as an injury caused by an external force that results in the disruption of normal brain function. In the United States, between 2016–2017, there were approximately 451,000 cases of TBI that resulted in hospitalization. The most common mechanisms of injury contributing to TBI were unintentional falls and motor vehicle crashes.
  • 955
  • 05 Aug 2021
Topic Review
Treating Epilepsy with Natural Products
Epilepsy is a neurological disease characterized by recurrent seizures that can lead to uncontrollable muscle twitching, changes in sensitivity to sensory perceptions, and disorders of consciousness. Although modern medicine has effective antiepileptic drugs, the need for accessible and cost-effective medication is urgent, and products derived from plants could offer a solution.
  • 234
  • 10 Aug 2023
Topic Review
Treating Early and Advanced Stage of Diabetic Retinopathy
A brief overview about the advances in the experimental field on the treatment of early stages of diabetic retinopathy (ESDR), as well as the main gaps to be filled will be given. In addition, a critical view on the current clinical practice for treating advanced stages of diabetic retinopathy (ASDR) will be provided.
  • 367
  • 23 Aug 2022
Topic Review
Treating Delusional Disorder with Antipsychotics
Delusional disorder (DD) has been considered a treatment-resistant disorder, with antipsychotics acknowledged as the best. It is possible that the discovery of the right drug could turn treatment resistance into treatment response.
  • 1.2K
  • 29 Dec 2022
Topic Review
Treating Chronic Pain of COVID-19
Careful triage of patients is mandatory in order to avoid overcrowding of hospital spaces. Telemedicine could represent a promising tool to replace in-person visits and as a screening tool prior to admitting patients to hospitals. Opioid medications can affect the immune response, and therefore, care should be taken prior to initiating new treatments and increasing dosages. Epidural steroids should be avoided or limited to the lowest effective dose. Non urgent interventional procedures such as spinal cord stimulation and intrathecal pumps should be postponed. The use of personal protective equipment and disinfectants represent an important component of the strategy to prevent viral spread to operators and cross-infection between patients due to the SARS-CoV-2 outbreaks. 
  • 369
  • 24 Nov 2021
Topic Review
Treat-to-Target in Systemic Lupus Erythematosus
Treat-to-target is a therapeutic approach based on adjustments to treatment at set intervals in order to achieve well-defined, clinically relevant targets. This approach has been successfully applied to many chronic conditions, and in rheumatology promising results have emerged for rheumatoid arthritis. For systemic lupus erythematosus (SLE), defining the most meaningful treatment targets has been challenging, due to disease complexity and heterogeneity. Control of disease activity, the reduction of damage accrual and the patient’s quality of life should be considered as the main targets in SLE, and several new drugs are emerging to achieve these targets. 
  • 233
  • 13 Jun 2023
Topic Review
Treat Preeclampsia by Targeting NFĸB by Drugs
Preeclampsia (PE) is characterised by high levels and activity of the transcription factor Nuclear Factor kappa B (NFĸB) in the maternal blood and placental cells. This factor is responsible for the regulation of over 400 genes known to influence processes related to inflammation, apoptosis and angiogenesis, and cellular responses to oxidative stress and hypoxia. Although high NFĸB activity induces hypoxia and inflammation, which are beneficial for the process of implantation, NFĸB level should be reduced in the later stages of physiological pregnancy to favour maternal immunosuppression and maintain gestation. It is believed that the downregulation of NFĸB activity by pharmacotherapy might be a promising way to treat preeclampsia. 
  • 706
  • 10 May 2022
Topic Review
Treat COVID-19 through Mass Spectrometry and Next-Generation Sequencing
COVID-19 is caused by a coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The difficulty in containing SARS-CoV-2 has underscored the need for techniques such as mass spectrometry in the diagnosis and treatment of COVID-19. Mass spectrometry-based methods have been employed in several studies to detect changes in interactions among host proteins, and between host and viral proteins in COVID-19 patients. The methods have also been used to characterize host and viral proteins, and analyze lipid metabolism in COVID-19 patients. Information obtained using the above methods are complemented by high-throughput analysis of transcriptomic and epigenomic changes associated with COVID-19, coupled with next-generation sequencing.
  • 514
  • 22 Nov 2021
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