Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Bioactive Polymers via the Biginelli Reaction
Multicomponent reactions (MCRs) have been used to prepare polymers with appealing functions. The Biginelli reaction, one of the oldest and most famous MCRs, has sparked new scientific discoveries in polymer chemistry since 2013. The applications of the Biginelli reaction in developing functional polymers are mainly focusing on polymers that can be used in the biomedical area as antioxidants, anticancer agents, and bioimaging probes.
  • 478
  • 22 Nov 2022
Topic Review
Bioactivity of Bisindolylmaleimides and Derivatives
Bisindolylmaleimide (BIM)-type compounds arise from natural sources such as arcyriarubin and are biosynthetically related to indolocarbazoles. BIMs are commonly the immediate synthetic precursors of indolocarbazoles, lacking a central bond between the two aromatic units and making them more flexible and drug-like. Synthetic endeavours within this class of compounds are broad and have led to the development of both remarkably potent and selective protein kinase inhibitors. Clinical BIM examples include ruboxistaurin and enzastaurin, which are highly active inhibitors of protein kinase C-β. While BIMs are widely recognised as protein kinase inhibitors, other modes of activity have been reported, including the inhibition of calcium signalling and antimicrobial activity. BIMs can be highly functionalised or chemically manipulated, which provides the opportunity to generate new derivatives with unique biological profiles. Critically, structural differences can be used to exploit new bioactivity and therefore it is imperative to discover new chemical entities to address new targets. 
  • 269
  • 13 Sep 2023
Topic Review
Bioactivity of Steroidal Arylidene Derivatives
Steroids constitute a unique class of chemical compounds, playing an important role in physiopathological processes, and have high pharmacological interest. Due to their straightforward preparation and intrinsic chemical reactivity, steroidal arylidene derivatives are important synthetic intermediates for the preparation of other compounds, particularly bearing heterocyclic systems, in addition to their relevant bioactivity with potential pharmacological interest. 
  • 545
  • 29 Apr 2021
Topic Review
Bioadhesive Biomaterials for Medical Application
This entry deliberates about the importance of polymer based bioadhesive biomaterial’s medical application in healthcare and redefining healthcare management. Nowadays application of bioadhesion in health sector is one of the great interest for various researchers, due to its recent advances in their formulation development. Actually, this area of study is considered as an active multidisciplinary research approach, where engineers, scientists—including chemists, physicists, biologists, and medical experts—materials’ producers, and manufacturers combine their knowledge in order to provide a better healthcare. Moreover, while discussing about the implications of value-based healthcare, it is necessary to mention that health comprises three main domains namely: physical, mental, and social health that prioritized not only the quality healthcare, but it also enables to measure the outcomes of medical interventions. In addition, this conceptual article provides an understanding about the consequences of natural or synthetic polymer based bioadhesion of biomaterials and its significance for redefining healthcare management as a novel approach. Furthermore, research assumptions highlights that the quality healthcare concept has recently become a burning topic where, healthcare service providers, private research institutes, government authorities, public service boards, associations and academics took initiative to restructure the health care system to create value for patients and increase their satisfaction, and lead ultimately to a healthier society.
  • 1.4K
  • 28 Sep 2021
Topic Review
Bioapplications of Amphiphilic Janus Dendrimers
Amphiphilic Janus dendrimers (JDs) can be defined as dendritic macromolecules made of two dendrons with opposite polarities, which either differ from each other by their terminal groups, or their structures differ entirely. Amphiphilic JDs are named following a more or less general scheme that encompass in this order, the lipophilic dendrons, the core if exists, and the hydrophilic dendrons. The unique architectures of amphiphilic Janus dendrimers, with multifunctional terminal groups, different structures of branches in a single molecule (beside the capacity of self-assembly in aqueous media forming dendrimersomes, which in turn benefit from properties like predictable size and thickness, stability and biocompatibility), constitute premises for a wide range of biomedical applications where conventional dendrimers have failed.
  • 557
  • 15 Feb 2023
Topic Review
Bioavailability of Lingonberry Polyphenols
Lingonberry (Vaccinium vitis-idaea) is less prevalent in the daily human diet because they are collected from the wild, and plant breeding of lingonberry is still on a small scale. Lingonberries are classed as “superfruits” with the highest content of antioxidants among berries and a broad range of health-promoting effects. Many studies showed various beneficial effects of lingonberries, such as anti-inflammatory, antioxidant, and anticancer activities. Lingonberries have been shown to prevent low-grade inflammation and diet-induced obesity in diabetic animals. Moreover, lingonberry intake has been associated with a beneficial effect on preventing and treating brain aging and neurodegenerative disorders.
  • 917
  • 03 Jun 2021
Topic Review
Biocatalyzed Redox Processes Employing Green Reaction Media
Biocatalysis can be defined in a broad sense as the mediation of chemical reactions by means of biological systems, including isolated enzymes, whole cells or cell-free extracts. In some circumstances, the aqueous buffer medium normally employed in biocatalytic procedures is not the best option to develop these processes, due to solubility and/or inhibition issues, requiring biocatalyzed redox procedures to circumvent these drawbacks, by developing novel green non-conventional media, including the use of biobased solvents, reactions conducted in neat conditions and the application of neoteric solvents such as deep eutectic solvents. 
  • 461
  • 05 Jul 2022
Topic Review
Bioceramic Materials Used in Regenerative Dentistry
To improve the oral and dental health of the population, regenerative dentistry is a very promising approach that aims both to prevent oral–dental deterioration and to restore the anatomy and functionality of diseased teeth. To this end, it draws on new advances in procedures based on cell biology and new biomaterials. Synthetic biomimetic materials, and particularly bioceramics are undoubtedly fundamental elements in the development of these advanced dental therapies, as the calcium phosphate type formulations are the natural bioceramic components of dental and bone tissues. To this must be added the breakthrough achieved with the new silica-based bioactive ceramic compositions, capable of stimulating biological mineralization processes.
  • 346
  • 24 Oct 2023
Topic Review
Biochar and Cementitious Composites
Cementitious materials are one of the most used infrastructure materials worldwide due to their low cost, well-developed production methods, and well adaptability to varying environmental conditions. Cementitious composites are mainly divided into three groups, i.e., concrete, mortar and paste. Being quasi brittle, they are prone to cracking, which greatly compromises their strength and durability. Due significance has been given to mitigate the brittle behavior of cementitious composites in the past: Various studies are available, intended at improving the tensile strain capacity of the cementitious materials. Apart from conventional steel reinforcement, inclusion of fibers has remained the focus of many studies.
  • 681
  • 21 Jun 2021
Topic Review
Biochar as Alternative Material for Heavy Metal Adsorption
Biochar is a specific carbon obtained by a pyrolysis process from different feedstocks, as an alternative material for heavy metal adsorption from groundwater. Many studies have been conducted regarding the application of innovative materials to water decontamination to develop a more sustainable approach to remediation processes. 
  • 197
  • 23 Feb 2024
  • Page
  • of
  • 467
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Video Production Service
Feedback