Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Hybrid Biocomposites
Bio-based composites are reinforced polymeric materials in which one of the matrix and reinforcement components or both are from bio-based origins. The biocomposite industry has recently drawn great attention for diverse applications, from household articles to automobiles. This is owing to their low cost, biodegradability, being lightweight, availability, and environmental concerns over synthetic and nonrenewable materials derived from limited resources like fossil fuel. The focus has slowly shifted from traditional biocomposite systems, including thermoplastic polymers reinforced with natural fibers, to more advanced systems called hybrid biocomposites. Hybridization of bio-based fibers/matrices and synthetic ones offers a new strategy to overcome the shortcomings of purely natural fibers or matrices. By incorporating two or more reinforcement types into a single composite, it is possible to not only maintain the advantages of both types but also alleviate some disadvantages of one type of reinforcement by another one. 
  • 2.2K
  • 13 Dec 2020
Topic Review
Hybrid Azine Derivatives
Infectious diseases caused by microorganisms are a major threat to human health, mostly because of drug resistance, multi-drug resistance and extensive-drug-resistance phenomena to microbial pathogens. During the past, obtaining hybrid azaheterocyclic drugs represents a powerful and attractive approach in modern antimicrobial therapy with very promising results including overcoming microbial drug resistance.
  • 537
  • 01 Dec 2022
Topic Review
Hyaluronic Acid-Mediated Phenolic Compound Nanodelivery for Cancer Therapy
Phenolic compounds are bioactive phytochemicals showing a wide range of pharmacological activities, including anti-inflammatory, antioxidant, immunomodulatory, and anticancer effects. Moreover, they are associated with fewer side effects compared to most currently used antitumor drugs. Combinations of phenolic compounds with commonly used drugs have been largely studied as an approach aimed at enhancing the efficacy of anticancer drugs and reducing their deleterious systemic effects. In addition, some of these compounds are reported to reduce tumor cell drug resistance by modulating different signaling pathways. However, often, their application is limited due to their chemical instability, low water solubility, or scarce bioavailability. Nanoformulations, including polyphenols in combination or not with anticancer drugs, represent a suitable strategy to enhance their stability and bioavailability and, thus, improve their therapeutic activity. 
  • 381
  • 20 Jun 2023
Topic Review
Hyaluronic Acid-Conjugated Carbon Nanomaterials
Hyaluronic acid (HA) has been implemented for chemo and photothermal therapy to target tumour cells overexpressing the CD44+ receptor. HA-targeting hybrid systems allows carbon nanomaterial (CNM) carriers to efficiently deliver anticancer drugs, such as doxorubicin and gemcitabine, to the tumour sites. 
  • 657
  • 07 Jan 2022
Topic Review
Hyaluronic acid-based theranostic nanomedicines
Hyaluronic acid (HA) is a natural mucopolysaccharide and has many useful advantages, including biocompatibility, non-immunogenicity, chemical versatility, non-toxicity, biodegradability, and high hydrophilicity. Numerous tumor cells overexpress several receptors that have a high binding affinity for HA, while these receptors are poorly expressed in normal body cells. HA-based drug delivery carriers can offer improved solubility and stability of anticancer drugs in biological environments and allow for the targeting of cancer treatments. Based on these benefits, HA has been widely investigated as a promising material for developing the advanced clinical cancer therapies in various formulations, including nanoparticles, micelles, liposomes, and hydrogels, combined with other materials.
  • 1.5K
  • 31 Dec 2020
Topic Review
Hyaluronic Acid-Based Scaffolds
There are HA-based scaffolds that can be used in wound healing as potential bioactive dressings such as bandages, topical gels, microspheres, nanoparticles, hydrocolloids, foams, transdermal/matrix patches, etc. Hussain et al. reported HA-functionalized nanoparticles for the co-delivery of resveratrol and curcumin for chronic diabetic wound treatment. 
  • 765
  • 14 Jul 2021
Topic Review
Hyaluronic Acid in Treating IVD
High molecular weight hyaluronic acid (HMW HA) and HA-based biomaterials used as therapeutic delivery platforms have been trialled in preclinical models and clinical trials. 
  • 1.2K
  • 12 Oct 2020
Topic Review
Hyaluronic Acid Hydrogels
Hyaluronic acid (HA) hydrogels display a wide variety of biomedical applications ranging from tissue engineering to drug vehiculization and controlled release. This entry compiles the currently used approaches for the development of hyaluronic acid hydrogels under physiological/mild conditions.
  • 1.3K
  • 15 Sep 2021
Topic Review
Hyaluronic Acid for Tissue Engineering
Polysaccharides such as hyaluronic acid (HA) which is omnipresent in the human body and exert pleiotropic biological functions such as tissue repair and tissue regeneration, may be exploited for cosmetics development, esthetic medicine, tissue engineering and regenerative medicine. In this work, the authors describe the excellent biocompatibility and biodegradability of HA-derived hydrogels with make them ideal materials for tissue engineering applications.
  • 1.3K
  • 27 May 2021
Topic Review
Hyaluronic Acid
Hyaluronic acid, as a natural linear polysaccharide, has attracted researchers’ attention from its initial detection and isolation from tissues in 1934 until the present day. Due to biocompatibility and a high biodegradation of hyaluronic acid, it finds wide application in bioengineering and biomedicine: from biorevitalizing skin cosmetics and endoprostheses of joint fluid to polymeric scaffolds and wound dressings. However, the main properties of aqueous polysaccharide solutions with different molecular weights are different. Moreover, the therapeutic effect of hyaluronic acid-based preparations directly depends on the molecular weight of the biopolymer. The present entry collects the information about hyaluronic acid and its original properties. Particular emphasis is placed on the structural, physical and physico-chemical properties of hyaluronic acid in water solutions, as well as their degradability.
  • 5.2K
  • 31 Aug 2020
  • Page
  • of
  • 467
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
ScholarVision Creations
Feedback