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Topic Review
Biography
Topic Review
Transdermal Drug Delivery System
Transdermal drug delivery system (TDDS) is an attractive method for drug delivery with convenient application, less first-pass effect, and fewer systemic side effects. Among all generations of TDDS, transdermal nanocarriers show the greatest clinical potential because of their non-invasive properties and high drug delivery efficiency. However, it is still difficult to design optimal transdermal nanocarriers to overcome the skin barrier, control drug release, and achieve targeting. Hence, surface modification becomes a promising strategy to optimize and functionalize the transdermal nanocarriers with enhanced penetration efficiency, controlled drug release profile, and targeting drug delivery.
964
14 Dec 2022
Topic Review
Tragia L. Genus
Tragia L. is a genus of plants belonging to the Euphorbiaceae family with worldwide intertropical distribution, composed of more than 150 species.
1.1K
16 May 2022
Topic Review
Traditional Group-IV Material Batteries through Ion Migration
Ion migration refers to the process of ions moving within a medium driven by an external electric field or a chemical gradient. The prerequisite for the implementation of ion migration technology lies in the construction of suitable electrodes, electrolytes, and media. Group-IV materials, due to their abundant raw materials, low production costs, non-toxic nature, and excellent electrochemical properties, serve as ideal anode materials for various ion migration-based batteries. Group-IV materials, as crucial components of ion migration-driven energy storage technologies, have been a focal point of research for decades. Various studies encompass the design and fabrication of rational structures, as well as selecting metal ions with different valence states (Li+, Na+, K+, Zn2+, Mg2+, Al3+, etc.) to enhance the performance of ion batteries.
97
19 Dec 2023
Topic Review
Tracing the Glycine from Quantum Chemical Simulations
Glycine (Gly), NH2CH2COOH, is the simplest amino acid. Although it has not been directly detected in the interstellar gas-phase medium, it has been identified in comets and meteorites, and its synthesis in these environments has been simulated in terrestrial laboratory experiments. Likewise, condensation of Gly to form peptides in scenarios resembling those present in a primordial Earth has been demonstrated experimentally. Thus, Gly is a paradigmatic system for biomolecular building blocks to investigate how they can be synthesized in astrophysical environments, transported and delivered by fragments of asteroids (meteorites, once they land on Earth) and comets (interplanetary dust particles that land on Earth) to the primitive Earth, and there react to form biopolymers as a step towards the emergence of life.
525
24 Jun 2022
Topic Review
Trabecular Tantalum
Tantalum has known ever wider applications for the production of endosseous implantable devices in the orthopedic and dental fields. Its excellent performances are due to its capacity to stimulate new bone formation, thus improving implant integration and stable fixation. Tantalum’s mechanical features can be mainly adjusted by controlling its porosity thanks to a number of versatile fabrication techniques, which allow obtaining an elastic modulus similar to that of bone tissue, thus limiting the stress-shielding effect.
369
27 Feb 2023
Topic Review
Toxicological Risks of the Cobalt–Chromium Alloys in Dentistry
Cobalt–chromium (Co-Cr) alloys have been used for a long period of time in dentistry, but several risk factors remain involved. The toxicological risk of Co-Cr dental alloys is actually a sensitive subject with the European regulatory changes, namely regulation (EU) 2017/745 and annex VI to the CLP regulation (EC) 1972/2008. Studies assessing Co-Cr dental alloys’ biocompatibility are urgently needed.
1.9K
22 Feb 2023
Topic Review
Toxicity of Titanium Compounds
Titanium and its compounds are broadly used in both industrial and domestic products, including jet engines, missiles, prostheses, implants, pigments, cosmetics, food, and photocatalysts for environmental purification and solar energy conversion. Although titanium/titania-containing materials are usually safe for human, animals and environment, increasing concerns on their negative impacts have been postulated. We have reported the state of knowledge about toxicity of titanium, its alloys and oxides. Due to the alarming increase in titania/titanium applications in various daily care products and medical treatment (e.g. dental implants) the possible toxicity and environmental impact should be considered. The collected data might allow to identify some harms associated with using of titania and titanium compounds.
4.3K
21 Feb 2021
Topic Review
Towards the Commercialization of Solid Oxide Fuel Cells
The solid oxide fuel cell (SOFC) has become a promising energy conversion technology due to its high efficiency and low environmental impact. Though there are several reviews on SOFCs, comprehensive reports that simultaneously combine the latest developments in materials and integration strategies are very limited. This paper addresses those issues and discusses SOFCs working principles, design types, the fuels used, and the required features for electrodes and electrolytes.
511
21 Dec 2021
Topic Review
Toughening Approaches of Recycled Polystyrene
Several environmental and techno-economic assessments highlighted the advantage of placing polystyrene-based materials in a circular loop, from production to waste generation to product refabrication, either following the mechanical or thermochemical routes.
1.0K
22 Nov 2022
Topic Review
Total Polyphenol Content in Food Samples and Nutraceuticals
Total polyphenol content and antioxidant capacity were estimated in various food and nutraceutical samples. These were analyzed by using two antioxidant assays—ferric reducing antioxidant power (FRAP) and Folin–Ciocalteu (FC)—and a reversed-phase high performance liquid chromatography (HPLC), with a focus on providing compositional fingerprints dealing with polyphenolic compounds. A preliminary data exploration via principal component analysis (PCA) revealed that HPLC fingerprints were suitable chemical descriptors to classify the analyzed samples according to their nature. Moreover, chromatographic data were correlated with antioxidant data using partial least squares (PLS) regression.
532
06 Apr 2022
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