Topic Review
Separation and Analytical Techniques Used in Snake Venomics
The deleterious consequences of snake envenomation are due to the extreme protein complexity of snake venoms. Therefore, the identification of their components is crucial for understanding the clinical manifestations of envenomation pathophysiology and for the development of effective antivenoms. In addition, snake venoms are considered as libraries of bioactive molecules that can be used to develop innovative drugs. Numerous separation and analytical techniques are combined to study snake venom composition including chromatographic and electrophoretic techniques.
  • 657
  • 28 Jul 2022
Topic Review
Laser-Induced Breakdown Spectroscopy for Food Quality Evaluation
Laser-induced Breakdown Spectroscopy (LIBS) is becoming an increasingly popular analytical technique for characterizing and identifying various products; its multi-element analysis, fast response, remote sensing, and sample preparation is minimal or nonexistent, and low running costs can significantly accelerate the analysis of foods with medicinal properties (FMPs). 
  • 683
  • 28 Jul 2022
Topic Review
In Vitro Drug Release Methods for Drug-Eluting Stents
The drug release profile of drug-eluting stents (DESs) is affected by a number of factors, including the formulation, design, and physicochemical properties of the utilized material. DES has been around for twenty years and despite its widespread clinical use, and efficacy in lowering the rate of target lesion restenosis, it still requires additional development to reduce side effects and provide long-term clinical stability. Unfortunately, for analyzing these implants, there is still no globally accepted in vitro test method. This is owing to the stent’s complexity as well as the dynamic arterial compartments of the blood and vascular wall. The former is the source of numerous biological, chemical, and physical mechanisms that are more commonly observed in tissue, lumen, and DES. As a result, universalizing bio-relevant apparatus, suitable for liberation testing of such complex implants is difficult.
  • 299
  • 27 Jul 2022
Topic Review
Analysis Methodology of Precursors to 3-Sulfanylhexan-1-ol in Wine
Volatile polyfunctional thiol compounds, particularly 3-sulfanylhexan-1-ol (3SH) and 3-sulfanylhexyl acetate (3SHA), are key odorants contributing to the aroma profile of many wine styles, generally imparting tropical grapefruit and passionfruit aromas. 3SH and 3SHA are present in negligible concentrations in the grape berry, juice, and must, suggesting that they are released from non-volatile precursors present in the grape. The exploration of the nature and biogenesis of these precursors to 3SH and 3SHA has proven important for the elucidation of polyfunctional thiol biogenesis during alcoholic fermentation.
  • 691
  • 27 Jul 2022
Topic Review
Analytical Techniques for Detection of Quantum Dots
Since the discovery of Quantum Dots (QDs) by Alexey I. Ekimov in 1981, the interest of researchers in that particular type of nanomaterials (NMs) with unique optical and electrical properties has been increasing year by year. Thus, since 2009, the number of scientific articles published on this topic has not been less than a thousand a year. The increasing use of QDs due to their biomedical, pharmaceutical, biological, photovoltaics or computing applications, as well as many other high-tech uses such as for displays and solid-state lighting (SSL), has given rise to a considerable number of studies about its potential toxicity. However, there are a really low number of reported studies on the detection and quantification of QDs, and these include ICP–MS and electrochemical analysis, which are the most common quantification techniques employed for this purpose. Keeping in mind both human health and environmental risks of QDs as well as the scarcity of analytical techniques and methodological approaches for their detection, the adaptation of existing techniques and methods used with other NMs appears necessary. 
  • 617
  • 27 Jul 2022
Topic Review
Perovskite Semiconductor Field–Effect Transistors
Perovskite materials are considered as the most alluring successor to the conventional semiconductor materials to fabricate solar cells, light emitting diodes and electronic displays. However, the use of the perovskite semiconductors as a channel material in field effect transistors (FET) are much lower than expected due to the poor performance of the devices. Despite low attention, the perovskite FETs are used in widespread applications on account of their unique opto-electrical properties. 
  • 1.6K
  • 27 Jul 2022
Topic Review
Ionic Liquids in Liquid–Liquid Microextraction
Ionic liquids (ILs) are a new chemical medium and soft functional material developed under the framework of green chemistry and possess many unique properties, such as low melting points, low-to-negligible vapor pressures, excellent solubility, structural designability and high thermal stability. 
  • 910
  • 26 Jul 2022
Topic Review
Modification of Glucomannan as an Excipient
Glucomannan (GM) is a polysaccharide generally extracted from the tuber of Amorphophallus konjac. It consists of mannose and glucose residues linked by β-(1-4) and exhibits hydrocolloid characteristics which can be applied as thickening and gelling agents. However, it has poor water resistance and low mechanical strength when used as an excipient in solid form. Several physical and chemical modifications have been carried out to improve these drawbacks. Chemical modification involves the substitution of functional groups in GM’s structure including esterification and etherification. It causes a decrease in its high hydrophilic film behavior and produce water-resistant films. Physical modification involves mixing native GM with other excipients through processes involving milling, moisture, temperature, pressure, radiation, etc. It causes variations to particle size, shape, surface properties, porosity, density, and to functional properties such as swelling capacity and gelation ability
  • 767
  • 26 Jul 2022
Topic Review
Bio-Lubricants
An extremely efficient lubrication system is achieved in synovial joints by means of bio-lubricants and sophisticated nanostructured surfaces that work together.
  • 638
  • 25 Jul 2022
Topic Review
Design and Challenges of Antibiotic Molecularly Imprinted Polymers
Antibiotics constitute one of the emerging categories of persistent organic pollutants, characterised by their expansion of resistant pathogens. Antibiotic pollutants create a major public health challenge, with already identifiable detrimental effects on human and animal health. A fundamental aspect of controlling and preventing the spread of pollutants is the continuous screening and monitoring of environmental samples. Molecular imprinting is a state-of-the-art technique for designing robust biomimetic receptors called molecularly imprinted polymers (MIPs), which mimic natural biomolecules in target-selective recognition. When integrated with an appropriate sensor transducer, MIP demonstrates a potential for the needed environmental monitoring, thus justifying the observed rise in interest in this field of research. 
  • 564
  • 25 Jul 2022
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