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Topic Review
Nano-Scaled Materials and Polymer Integration in Biosensing Tools
The evolution of biosensors and diagnostic devices has been thriving in its ability to provide reliable tools with simplified operation steps. These evolutions have paved the way for further advances in sensing materials, strategies, and device structures. Polymeric composite materials can be formed into nanostructures and networks of different types, including hydrogels, vesicles, dendrimers, molecularly imprinted polymers (MIP), etc. Due to their biocompatibility, flexibility, and low prices, they are promising tools for future lab-on-chip devices as both manufacturing materials and immobilization surfaces. Polymers can also allow the construction of scaffold materials and 3D structures that further elevate the sensing capabilities of traditional 2D biosensors.
  • 516
  • 19 Jun 2022
Topic Review
Nano-Scaffolds in Bone Tissue Engineering
Numerous surgeries are carried out to replace tissues that have been harmed by an illness or an accident. Due to various surgical interventions and the requirement of bone substitutes, the emerging field of bone tissue engineering attempts to repair damaged tissues with the help of scaffolds. These scaffolds act as template for bone regeneration by controlling the development of new cells. For the creation of functional tissues and organs, there are three elements of bone tissue engineering that play very crucial role: cells, signals and scaffolds. For the achievement of these aims, various types of natural polymers, like chitosan, chitin, cellulose, albumin and silk fibroin, have been used for the preparation of scaffolds. Scaffolds produced from natural polymers have many advantages: they are less immunogenic as well as being biodegradable, biocompatible, non-toxic and cost effective. The hierarchal structure of bone, from microscale to nanoscale, is mostly made up of organic and inorganic components like nanohydroxyapatite and collagen components. 
  • 186
  • 10 Jan 2024
Topic Review
Nano-Enzymes in Electrochemical Detection of Reactive Oxygen Species
Reactive oxygen species (ROS) play an important role in maintaining human health and are recognized as indicators of oxidative stress linked to various conditions such as neurodegenerative and cardiovascular diseases, as well as cancer. Consequently, detecting ROS levels in biological systems is crucial for biomedical and analytical research. Electrochemical approaches offer promising opportunities for ROS determination due to their exceptional sensitivity, speed, and simplicity of equipment. 
  • 282
  • 30 Aug 2023
Topic Review
Nano-Enabled Platforms and Depression
Nanotechnology has aided in the advancement of drug delivery for the treatment of several neurological disorders including depression. Depression is a relatively common mental disorder which is characterized by a severe imbalance of neurotransmitters. Several current therapeutic regimens against depression display drawbacks which include low bioavailability, delayed therapeutic outcome, undesirable side effects and drug toxicity due to high doses.
  • 658
  • 19 May 2021
Topic Review
Nano-Drug Delivery to Target Macrophages
Macrophages are the most important innate immune cells that participate in various inflammation-related diseases. Therefore, macrophage-related pathological processes are essential targets in the diagnosis and treatment of diseases. Since nanoparticles (NPs) can be preferentially taken up by macrophages, NPs have attracted most attention for specific macrophage-targeting. 
  • 969
  • 10 Jun 2022
Topic Review
Nano-Biomaterials for Retinal Regeneration
Nanoscience and nanotechnology have revolutionized key areas of environmental sciences, including biological and physical sciences. Nanoscience is useful in interconnecting these sciences to find new hybrid avenues targeted at improving daily life. Pharmaceuticals, regenerative medicine, and stem cell research are among the prominent segments of biological sciences that will be improved by nanostructure innovations. Nanoparticles, nanowires, hybrid nanostructures, and nanoscaffolds, that have been useful in mice for ocular tissue engineering and regeneration.
  • 768
  • 22 Sep 2021
Topic Review
Nano-(Q)SAR for Cytotoxicity Prediction of Engineered Nanomaterials
Nanomaterials and nanoparticles (NPs) possess unique physico-chemical properties (size, shape, chemical composition, physiochemical stability, crystal structure, surface area, surface energy, and surface roughness), which give them beneficial characteristics. Quantitative structure-activity relationship, or QSAR, is an area of molecular modeling that studies relationships between structure and activity using mathematical statistics and machine learning methods. QSAR is efficiently used to predict toxicity of chemical substances.
  • 486
  • 20 Dec 2021
Topic Review
Nano-, Micro- and Macro-Scale Impact Tests
Impact resistance is critical in many applications of coating systems involving highly loaded mechanical contact. Nano-impact testing utilises the depth-sensing capability of a multifunctional nanomechanical test system (NanoTest system, Micro Materials Ltd., Wrexham, UK) to perform impact testing at strain rates that are several orders of magnitude higher than those in quasi-static indentation tests.
  • 607
  • 21 Jun 2022
Topic Review
Nano Skin Care Formulations
The term “cosmeceutical” was first mentioned in 1984 by Dr. Albert Kligman (University of Pennsylvania), who used it to describe a new category of products that could be classified as more than just cosmetics or pharmaceuticals. According to Dr. Kligman, a cosmeceutical is “a topical preparation that is sold as a cosmetic but has performance characteristics suggestive of a pharmaceutical effect” and therefore might have a pharmaceutical therapeutic effect, but not essentially a biological therapeutic benefit. Since the discovery of the anti-ageing effects of tretinoin, the use of alpha hydroxy acids as exfoliants and for skin rejuvenation, and the use of vitamin C in topical formulations as an antioxidant, the market for cosmeceuticals has grown exponentially and has taken over the personal care industry. Since the term “cosmeceutical” is not yet well established, it is often used in the cosmetic industry to emphasise the specific mechanism of action of the ingredients included in modern skin care formulations. Despite the confusion about their definition and scope, about 40% of dermatologist prescriptions around the world are cosmeceuticals. Nowadays, the use of nanotechnology to improve the efficacy of APIS is a great success.
  • 1.0K
  • 21 Oct 2021
Topic Review
N,N-Dimethylacrylamide-Based Hydrogels
N,N-dimethylacrylamide produces hydrogel when polymerized with cross-linkers. Moreover, poly(N,N-dimethylacrylamide) has gotten a lot of attention as it is commonly used as the hydrophilic side of copolymers due to its unique properties and high water solubility. In addition, van der Waals interactions between N,N-dimethylacrylamide and dye molecules even more increase the applicability of DMAA hydrogels.
  • 1.7K
  • 03 Dec 2021
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